• Journal of Korean Institute of Industrial Engineers
• /
• v.1 no.1
• /
• pp.41-56
• /
• 1975

In the past the pattern of business down-trend usually appeared in the form of, first, decrease in facility investment, then decrease in inventory level, followed by reduced level of consumption. But the pattern nowadays is becoming just the opposite, that is, first, consumption decrease, then inventory level increase, followed by restriction of facility investment. Also in the past, the greater effort was placed in strengthening of hardware areas through optimization and modernization of production means on the premise of sales. But lately software areas take most of the main effort to establish production mean with sales as its objective. Under these circumstances one of the real problems facing production activities today is the conflicting relationship between sales and production functions. This occurs due to differences of their view points. Then, in order to achieve maximum profit at the least cost, which is the ultimate objective of a production activity, the need arises to effectively coordinate sales demand and plant production capacity. For this purpose strong control means and function must be devised. In our case study example we illustrate a management technique for a combined planning function, of optimal coordination of product mixes utilizing a computerized linear programming model as control means of attaining maximum profit. It is hoped that this example help achieve some of corporate objectives.

• The Korean Journal of Food And Nutrition
• /
• v.19 no.3
• /
• pp.327-331
• /
• 2006

Zingiber officinale and Hizikia fusiforme(sea weed fusiforme) have long been used for food sources in Korea. The present study was performed to investigate the ex vivo effect of Zingiber officinale and Hizikia fusiforme on NO production in macrophage of mice. Seven to eight week old mices(Balb/c) were fed chew diet ad libitum and water extract of Zingiber officinale and Hizikia fusiforme was administrated orally at two different concentrations (50 and 500 mg/kg B.W.). every other day for two or four weeks NO(nitric oxide) production by activated macrophage was assessed by measuring nitrite, the stable NO metabolite, using Griess reaction assay. NO production were significantly enhanced in Zingiber officinale group at 500 mg/kg B.W. and in Hizikia fusiforme group at 50 mg/kg B.W. compared to the coresponding control groups. In conclusion, this study may suggest that Zingiber officinale and Hizikia fusiforme(sea weed fusiforme) extracts enhance the immune function by regulating NO production in macrophages of mice.

• Journal of the Korean Institute of Gas
• /
• v.21 no.3
• /
• pp.61-69
• /
• 2017

The commercial development of unconventional gas is pursued in North America because it is more feasible owing to the technology required to improve productivity. Shale reservoir have low permeability and gas production can be carried out through cracks generated by hydraulic fracturing. The decline rate during the initial production period is high, but very low latter on, there are significant variations from the initial production behavior. Therefore, in the prediction of the production rate using deterministic decline curve analysis(DCA), it is not possible to consider the uncertainty in the production behavior. In this study, production rate of the Eagle Ford shale is predicted by Arps Hyperbolic and Modified SEPD. To minimize the uncertainty in predicting the Estimated Ultimate Recovery(EUR), Monte Carlo simulation is used to multi-wells analysis. Also, kernel density function is applied to determine probability distribution of decline curve factors without any assumption.

• Journal of Technology Innovation
• /
• v.5 no.1
• /
• pp.150-180
• /
• 1997

This article introduces the five functions of the national innovation system(NIS). As one of social systems in the national level, the five generic functions of open system - production, boundary spanning, maintenance, adaptation, management functions - are applied to the NIS. The production function is the primary process, which produces innovative products and services of the NIS. The boundary spanning function is the function of procuring input and disposing the innovation output or aiding in these processes. Experienced R&D human resources, R&D funds, technology etc. are some of the components of the input of the NIS. The maintenance function is responsible for maintaining smooth operation and upkeeping the system in terms of various conditions. The adaptation function is to help the system change and adapt, and scan the environment for problems, opportunites, and technological developments. It has outward orientation, from the long-term view for the survival of the system. The management function carries out planning and control of the overall activities for the other four functions in order to effectiving run the system as a whole. Finally, this article discusses implications of the diagnosis of the national innovation system and the decision making process of S&T policy.

• Environmental and Resource Economics Review
• /
• v.13 no.4
• /
• pp.717-734
• /
• 2004

This paper examined the statistical goodness-of-fit tests for biological growth model in bioeconomic analysis. Some authors estimated usually growth function for fish in the world. However, few studies have estimated growth equations for the bivalve species. Thus, this paper studied the common functional forms of fitting growth equations for cham scallops considering environmental factors and production styles. The following functional forms are considered: linear, log-reciprocal, double log, polynomial and linear with interactions. Results of fitting these various functional forms with real data are compared and evaluated using standard statistical goodness-of-fit tests. Results also indicate that log-reciprocal function is statistically the best fit to the real data. Therefore, the log-reciprocal function is decided the best function describing cham scallop biological growth and hence might be useful for economic evaluation(i.e., optimal harvesting time).

• Journal of Microbiology and Biotechnology
• /
• v.13 no.6
• /
• pp.892-896
• /
• 2003

High-level expression of the lipase B26 gene from Bacillus pumilus was achieved using Bacillus subtilis Chungkookjang isolated from the Korean traditional fermented bean paste, Chungkookjang. For the secretory production of recombinant lipase B26 in a Bacillus host system, pLipB26 was constructed by ligating the lipase B26 gene into the recently designed Escherichia coli-Bacillus shuttle vector, pLipSM, and that was then transformed into B. subtilis Chungkookjang. Among the various vector, medium, and host combinations, B. subtilis Chungkookjang harboring the pLipB26 exhibited the highest lipase activity in PY medium, and B. subtilis Chungkookjang secreted two times more enzymes than B. subtilis DB 104 under the same condition. When B. subtilis Chungkookjang harboring the pLipB26 was cultured in a 5-1 jar-fermentor containing 21 of a PY medium, the maximum lipase activity (140 U/ml) and production yield (0.68 g/l) were obtained during the late exponential phase from a cell-free culture broth. Although B. subtilis Chungkookjang also secreted extracellular proteases at the late exponential phase, these results suggested the potential of B. subtilis Chungkookjang as a host for the secretory production of foreign proteins.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.29 no.2B
• /
• pp.173-179
• /
• 2009

Industrial water supplied by water resource project is essential input materials along with labor, capital and land for companies. It is very important to stably secure these input materials in order for the industry to generate additional values. If the supply of industrial water is stopped, it is known damage for the industry is greater than domestic water or agriculture water based on same amount of supply. Like this, the actual value of industrial water has been highly acknowledged from the intuitive perspective, but study on the value and benefits of industrial water has been rarely conducted. Therefore, this study verified the value of industrial water supplied from water resource project, and used marginal production value as a measure to estimate the benefits of industrial water in the analysis of economic efficiency. As a result of empirical analysis using Cobb-Douglas production function and Translog production function, industries' average marginal production value was $5,427KRW/m^3$ and $5,583KRW/m^3$ respectively. The marginal production value for eleven industries were estimated by using same method. The marginal production value by industries presented by this study will be used as important data to calculate benefits of industrial water in the future. Moreover, the result of this study will provide reasonable criteria for decision making on the allocation of water in emergency situation, and problem of resource supply from water resource project.

• Archives of design research
• /
• v.11 no.1
• /
• pp.43-52
• /
• 1998

In reflection of the current trend of times requiring the harmonization of nature, human being and scientific technologies, science museum has become more and more familiar to public and demand on it is also increasing. Information on the culture of science and technology is an engine for exploiting the future, particularly in the industrialized, informationalized and specialized society. Thus the science museum, the function of which is to convey such information, should be planned with the purpose of active and progressive communication. This purpose of planning can be achieved through well established process of the exhibition space production. This study focuses on the importance of the exhibition space production in the design of the science museum and proceeds as follows. 1. The concept of the exhibition space production is established following the review of function and the role of science museum. 2. The methods and the media used in the exhibition space production are suggested and the case study is made. 3. The scenarios for the exhibition space production planning are suggested and the effect and importance of the space production is enlightened. The result of this study shows that the space production increases the effectiveness of the exhibition in the science museum and that space production process should be reflected in planning the project.

• Journal of Korean Society of Transportation
• /
• v.24 no.5 s.91
• /
• pp.45-56
• /
• 2006

In order to construct an information pool on the production characteristics and efficiency of Korean railroad industry, various alternative approaches have to be applied. In this paper we present an empirical application of the distance function to measure the technical efficiency and the production characteristics of Korean railroad industry, The distance function firstly introduced by Shephard (1953) provides the advantage that it does not need information about prices, so it can accommodate the multiple output nature of the railway only using the quantifies as data. This is of great relevance in the context of the public sector such as railroad industry where there are often distinct control mechanisms on input prices. Also the distance function allows us to obtain a measure of technical efficiency as well as a measure of production characteristics. From annual data on Korean railroad industry during 1964-2004, multiple output distance function is estimated using quadratic programming model. The resulting technical efficiency estimates has tended to be improved over the period $1980{\sim}2004$. The indirect Morishima elasticities of substitution indicate that the substitutabilities for labor are relatively very low or impossible. The average scale elasticity is 2.7 which means that increasing the scale by 1per cent will result in an output increase by 2.7 percent. This result indicates that economies of scale are present in the Korean railroad industry.

• YAKHAK HOEJI
• /
• v.43 no.6
• /
• pp.851-860
• /
• 1999

The effects of antimycin A(AA), dodium azide ($NaN_3$) and 2,4-dinitrophenol (DNP), which inhibit mitochondrial ATP production, on cellular functions of cultured astrocytes were studied. High concentrations of AA $(50{\;}\mu\textrm{g}/ml),{\;}NaN_3$ (100mM) and DNP (20mM) significantly decreased 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) reduction, which was known to be related to mitochondrial function and then cel viability. AA ($50{\;}\mu\textrm{g}/ml$) increased lactate dehydrogenase (LDH) release and decreased [$^3H$] glutamate uptake, suggesting severe damage of cellular function by the concentrations of the compounds. Meanwhile, low concentrations of AA $(\leq{;\}10{\;}\mu\textrm{g}/ml),{\;}NaN_3{;\}(\leq{\;}50mM)$ and DNP ($\leq{\;}5mM$) significantly increased MTT reduction, the effect of which was specific to astrocytes. AA (5 and $10{\;}\mu\textrm{g}/ml$) did not affect LDH release and [$^3H$] glutamate uptake, indicating that these compounds increased MTT reduction at the low concentrations without cellular membrane damage. However, the low concentrations of AA produced significant decrease of MTT reduction in a glucose-free medium. Low concentrations of AA (1 and $5{\;}\mu\textrm{g}/ml$) did not change ATP production of astrocytes in the medium containing 10 mM glucose, but completely inhibited in a glucose-free medium, suggesting marked increase of cytosolic ATP production by the blockade of mitochondrial ATP production with low concentrations of AA. These results suggest that astrocytes have ability to enhance neuronal function or survival under conditions of incomplete ischemia or early by enhancement of glycolysis, and that cellular reduction of MTT occurs not only mitochondrially but also extramitchondrially.