• 제목/요약/키워드: probe level analysis

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Finding Interesting Genes Using Reliability in Various Gene Expression Models

  • Lee, Eun-Kyung;Cook, Dianne;Hoffman, Heike
    • Genomics & Informatics
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    • 제9권1호
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    • pp.28-36
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    • 2011
  • Most statistical methods for finding interesting genes are focusing on the summary values with large fold-changes or large variations. Very few methods consider the probe level data. We developed a new measure to detect reliability that incorporates the probe level data. This reliability measure is useful for exploring the microarray data without ignoring the probe level data. It is easy to calculate, and it can be used for all the other statistical methods as a good guideline to find real differentially expressed genes. Instead of filtering out genes before the analysis, we use whole genes in the analysis and make decisions with new reliability measures.

A Technique for Analyzing LSI Failures Using Wafer-level Emission Analysis System

  • Higuchi, Yasuhisa;Kawaguchi, Yasumasa;Sakazume, Tatsumi
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제1권1호
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    • pp.15-19
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    • 2001
  • Current leakage is the major failure mode of semiconductor device characteristic failures. Conventionally, failures such as short circuit breaks and gate breakdowns have been analyzed and the detected causes have been reflected in the fabrication process. By using a wafer-level emission-leakage failure analysis method (in-line QC), we analyzed leakage mode failure, which is the major failure detected during the probe inspection process for LSIs, typically DRAMs and CMOS logic LSIs. We have thus developed a new technique that copes with the critical structural failures and random failures that directly affect probe yields.

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울릉도 특별관측 수행평가 및 강수특성 분석 (The Performance Assessment of Special Observation Program (ProbeX-2009) and the Analysis on the Characteristics of Precipitation at the Ulleungdo)

  • 김기훈;김연희;김도우;장동언
    • 대기
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    • 제21권2호
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    • pp.185-196
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    • 2011
  • The performance assessment in radiosonde observation on the special observation program (ProbeX-2009) is performed and the characteristics of precipitation using Auto Weather System (AWS) and radiosonde data in 2009 at the Ulleungdo are investigated. The launching time, observation time, and maximum altitude of radiosonde are satisfied with the regulation from Korea Meteorological Administration (KMA) and World Meteorological Organization (WMO) but the duration of observational time of radiosonde is much shorter than that of the ProbeX-2007 because the altitude of launching site is higher than others in 2007. From the analysis of trajectories of radiosonde, most radiosondes at the Ulleungdo tend to move into the east because the westerly prevail at the middle latitude. However, when the Okhotsk high is expanded to the Korean peninsula and the north-westerly winds strengthen over the East Sea as the subtropical high is retreated, radiosonde tends to move into the south-west and south-east, respectively. Maximum distance appears at the end of observation level before May but the level of maximum distance is changed into 100 hPa after June because the prevailing wind direction is reversed from westerly to easterly at the stratosphere during summer time. The condition of precipitation was more correlated with the dynamic instability except Changma season. Precipitation in 2009 at the Ulleungdo occurred under the marine climate so that total precipitation amounts and precipitation intensity were increased and intensified during nighttime. The local environment favorable for the precipitation during nighttime was while the wind speed at the surface and the inflow from the shoreline were strengthened. Precipitation events also affected by synoptic condition but the localized effect induced by topography was more strengthened at the northern part of Ulleungdo.

거시교통류 모니터링 지표산출을 위한 적정 프로브차량 비율 결정에 관한 연구 (An Application of Sampling to Determine a Proper Rate of Probe Vehicles for Macroscopic Traffic Flow Monitoring Indices)

  • 심정숙;허현무;엄기종;이청원;안수한
    • 한국ITS학회 논문지
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    • 제9권2호
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    • pp.33-40
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    • 2010
  • 본 논문에서는 거시교통류 모니터링을 위한 세 가지 지표를 다루고 신뢰성 있는 지표산출에 필요한 적정 프로브차량 비율을 결정하기 위해 샘플링 기법을 이용하는 방법에 대하여 연구한다. 모니터링 세 가지 지표로는 Travel Time Index(TTI), Acceleration Noise(AN) 그리고 Two Fluid(TF)를 살펴보고, 적정 프로브 차량 비율의 결정방법으로는 절대오차를 이용한 표본크기의 결정방법과 상대오차를 이용한 표본크기의 결정방법에 대하여 고찰한다. 그리고 표본추출비율에 따른 지표 값 변동을 비교 검토하기 위해 서울시 강남지역의 대규모 자료를 이용하여 모의실험을 실시하였다. 모의실험 결과 교통수요 단계(Demand Level)가 증가함에 따라 상대오차를 이용한 표본 추출비율이 줄어들며, 추출비율은 허용오차, 링크통과차량의 수와 반비례 관계이므로 추출비율을 증가시킬수록 허용오차를 줄일 수 있음을 알 수 있었다.

아크 플라즈마 유동에 삽입된 엔탈피 탐침의 동작특성 실험 (Experimental analysis on the characteristics of enthalpy probe immersed in arc plasma flow)

  • 서준호;남준석;최성만;홍봉근;홍상희
    • 한국항공우주학회지
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    • 제38권12호
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    • pp.1240-1246
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    • 2010
  • 내경 1.5 mm, 외경 4.8 mm를 갖는 엔탈피 탐침을 설계 제작하고, 17 kW급 비이송식 직류 아크히터로부터 나오는 고엔탈피 Ar 아크 플라즈마 유동의 중심축을 따라 삽입하면서 탐침 첨두가 파괴될 때까지 온도와 속도를 측정하였다. 이 실험으로부터, 설계된 엔탈피 탐침은 대기압 조건에서 최대 12,000 K 의 온도와 600 m/s 의 속도를 갖는 고엔탈피아크 플라즈마 유동장에 대해 탐침 첨두의 파괴 없이 동작할 수 있음을 관찰하였다. 탐침첨두에서 형성되는 비압축성 열경계층 및 열속 방정식으로부터 이 경우의 아크 플라즈마 유동은 약 ${\sim}5{\times}10^7\;W/m^2$의 열속 부하를 전달한 것으로 추측되었다. 이로부터, 설계된 엔탈피 탐침은 $0{\sim}5{\times}10^7\;W/m^2$의 열속 범위 내에서 다양한 형태의 아크히터로부터 발생되는 넓은 범위의 플라즈마 온도, 속도 및 농도를 동시에 측정할 수 있을 것으로 기대된다.

CDMA 역방향 링크에서 OPEN LOOP 전력제어 알고리즘 분석 (Analysis of OPEN LOOP Power Control in CDMA Reverse Link)

  • 이철희;박종안
    • 한국통신학회논문지
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    • 제22권4호
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    • pp.804-811
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    • 1997
  • In the CDMA mobile communication system, reverse power control can be used to minimize the interference level for a good quality of the voice channel, and used to maxmize the system capacity. In this paper, we have analyed the environment of the K-parameter and the access procedure for the mobile station, and proposed a new algorithm for the access probe procedure of the station. K-parameter is determined according to the environment of the base station and access probe can adaptively control the power according to the position changes of the mobile station or the rapid and various state changes of the channel. Simulation results in the limited test environment show that it can increase the system capacity and decrease the power comsumption of the mobile station while maintaining the good and stable quality of the voice channel.

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Improving data reliability on oligonucleotide microarray

  • Yoon, Yeo-In;Lee, Young-Hak;Park, Jin-Hyun
    • 한국생물정보학회:학술대회논문집
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    • 한국생물정보시스템생물학회 2004년도 The 3rd Annual Conference for The Korean Society for Bioinformatics Association of Asian Societies for Bioinformatics 2004 Symposium
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    • pp.107-116
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    • 2004
  • The advent of microarray technologies gives an opportunity to moni tor the expression of ten thousands of genes, simultaneously. Such microarray data can be deteriorated by experimental errors and image artifacts, which generate non-negligible outliers that are estimated by 15% of typical microarray data. Thus, it is an important issue to detect and correct the se faulty probes prior to high-level data analysis such as classification or clustering. In this paper, we propose a systematic procedure for the detection of faulty probes and its proper correction in Genechip array based on multivariate statistical approaches. Principal component analysis (PCA), one of the most widely used multivariate statistical approaches, has been applied to construct a statistical correlation model with 20 pairs of probes for each gene. And, the faulty probes are identified by inspecting the squared prediction error (SPE) of each probe from the PCA model. Then, the outlying probes are reconstructed by the iterative optimization approach minimizing SPE. We used the public data presented from the gene chip project of human fibroblast cell. Through the application study, the proposed approach showed good performance for probe correction without removing faulty probes, which may be desirable in the viewpoint of the maximum use of data information.

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${\mu}-PD$ 법으로 성장시킨 near-stoichiometric 조성 $Zn:LiNbO_3$ fiber 단결정 성장 및 광손상 특성 (Crystal growth and optical properties of near-stoichiometric $Zn:LiNbO_3$ fiber single crystal by ${\mu}-PD$ method)

  • 이호준;서중원;신동익;송원영;윤대호
    • 한국결정성장학회지
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    • 제16권6호
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    • pp.235-239
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    • 2006
  • Micro-pulling down$({\mu}-PD)$법을 이용하여 직경 $0.8{\sim}1.0mm$, 길이 $30{\sim}35mm$의 ZnO가 첨가된 near-stoichiometric $LiNbO_3$, 단결정을 성장하였다. 성장된 결정의 결정구조를 powder x-tay diffraction(XRD) patterns으로 확인하였고, electron probe micro analysis(EPMA)를 이용하여 결정내 Zn 이온들이 균일하게 분포되었음을 확인하였다. 또한 2 mol% 이상의 ZnO 첨가시 $OH^-$ 흡수밴드의 특성이 크게 변화함을 관찰함으로써 ZnO 첨가량에 일치한 역치(threshold)가 존재함을 확인하였다.

한방부인과 임상실습교육에서 초음파 팬텀의 활용과 효과 (The Use and Educational Effect of Ultrasonic Phantom in Korean Medicine Obstetrics and Gynecology Clinical Practice Education)

  • 양승정;조성희
    • 대한한방부인과학회지
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    • 제35권2호
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    • pp.16-27
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    • 2022
  • Objectives: The purpose of this study is to analyze educational effect of ultrasound examination training with ultrasonic phantom in the department of Korean Medicine Obstetrics and Gynecology. Methods: All 4th grade students in 2021 and 2022 of school of Korean Medicine, Dong-Shin University must be trained in the department of Korean Medicine Obstetrics and Gynecology according to ultrasound examination training guideline including Objective Structured Clinical Examination (OSCE). After completing ultrasound examination training, we distributed questionnaires to them about a confidence before OSCE and after OSCE, difficulty in using ultrasound, ultrasound reading, difficulty with probe manipulation and computer operation, ultrasound understanding, clinical usefulness. And then, we analyzed the related factors including descriptive statistics, frequency analysis, student's t-test and paired t-test by SPSS 12.0. Results: Confidence in using ultrasound showed differences among students by gender and year, but it was not statistically significant. The difficulty of ultrasound use and ultrasound reading was at a moderate level, and the gender difference was not significant, and the difference between the practical students by year was statistically significant. The difficulty of the operation of the ultrasonic probe was at a normal level, and the difference between the students in practice by gender and year was not statistically significant. Although they answered that they had a very good understanding of the use of ultrasound, there was a gender difference and it was statistically significant, and practical students by year was not statistically significant. They answered that the effect on clinical use was very sufficient, but it was not statistically significant. The appropriateness of the practice time was evaluated at a moderate level. Conclusions: The use and educational effect of ultrasound examination using ultrasonic phantom in the department of Korean Medicine Obstetrics and Gynecology clinical practice education was very effective.

율촌 복합화력발전소 공내 재하 시험 (Pressuremeter Test in YULCHON Combined Cycle Power Plant)

  • 이용길;박경호
    • 한국지반환경공학회 논문집
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    • 제2권1호
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    • pp.5-13
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    • 2001
  • 본 논문의 목적은 율촌 복합화력발전소 부지에 대한 지지력 산정 및 지반 특성 파악을 위한 공내재하시험의 결과를 분석하는 것이다. 율촌 복합화력발전소 부지는 인근의 야산 토취장에서 매립토를 채취 운반하여 강제치환공법으로 성토하였으며, 지질은 상부로부터 산토, 준설매립해성점토, 실트집모래, 원지반해성점토층, 풍화대, 풍화암, 연암의 순으로 존재한다. 공내재하시험은 해성점성토층을 제외한 토층에 대하여 토층의 특성에 따라 각각 다른 크기의 Probe와 Membrane을 사용하여 수행하였으며, 콘시험과의 상관성, 내부 마찰각과의 관계 및 토질 특성을 파악하였다.

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