• 한국도서관정보학회지
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• 제5권
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• pp.1-31
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• 1978

This thesis is to discuss and prove the identity of the acts of the library and the character of the library which regards these as its objects. And this study is analyzed in view of per ceptual problems and scientific problems and scientific problems, in order to make clear the character of the acts of the library. In these processes, some basic propositions are extracted. First, culture can be found in arranged order. Second, human being can create culture by the acquisition of accmulated culture. Third, an individual is purposely related with culture. Fourth, culture is antonomous to mankind. And in this thesis, library science is defined as the systematic formation of mankind's pursuing acts, and to identify this definition, some theoretical models of library science have been offered as follows : Model I 1. Theory of making culture assets informative. 2. Theory of making culture assets empirical; that of imformation treatment. 3. Theory of medial acts of librarians. Model II 4. Theory of organic systems of libraries. Model III 5. Theory of guiding school activities. 6. Theory of extending the inhabitants' interests of communities. 7. Theory of a kind of resources in social improvement. Model IV 8. Theory of a means of principal approach to the succession of culture. In conclusion, this study is to prove that acts of libraries are the universal ones of those human being that are gualified to be the unique means to the creation of culture and, library science is a science that shapes concepts and rules to describe, to make explanation and to foretell these acts.

• Asian Pacific Journal of Cancer Prevention
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• 제15권3호
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• pp.1085-1091
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• 2014

Matrix metalloproteinases (MMPs) are a family of zinc dependent extracellular matrix (ECM) remodelling endopeptidases having the ability to degrade almost all components of extracellular matrix and implicated in various physiological as well as pathological processes. Carcinogenesis is a multistage process in which alteration of the microenvironment is required for conversion of normal tissue to a tumour. Extracellular matrix remodelling proteinases such as MMPs are principal mediators of alterations observed in the microenvironment during carcinogenesis and according to recent concepts not only have roles in invasion or late stages of cancer but also in regulating initial steps of carcinogenesis in a favourable or unfavourable manner. Establishment of relationships between MMP overproduction and cancer progression has stimulated the development of inhibitors that block proteolytic activity of these enzymes. In this review we discuss the MMP general structure, classification, regulation roles in relation to hallmarks of cancer and as targets for therapeutic intervention.

• Radiation Oncology Journal
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• 제32권3호
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• pp.103-115
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• 2014

To summarize current knowledge regarding mechanisms of radiation-induced normal tissue injury and medical countermeasures available to reduce its severity. Advances in radiation delivery using megavoltage and intensity-modulated radiation therapy have permitted delivery of higher doses of radiation to well-defined tumor target tissues. Injury to critical normal tissues and organs, however, poses substantial risks in the curative treatment of cancers, especially when radiation is administered in combination with chemotherapy. The principal pathogenesis is initiated by depletion of tissue stem cells and progenitor cells and damage to vascular endothelial microvessels. Emerging concepts of radiation-induced normal tissue toxicity suggest that the recovery and repopulation of stromal stem cells remain chronically impaired by long-lived free radicals, reactive oxygen species, and pro-inflammatory cytokines/chemokines resulting in progressive damage after radiation exposure. Better understanding the mechanisms mediating interactions among excessive generation of reactive oxygen species, production of pro-inflammatory cytokines and activated macrophages, and role of bone marrow-derived progenitor and stem cells may provide novel insight on the pathogenesis of radiation-induced injury of tissues. Further understanding the molecular signaling pathways of cytokines and chemokines would reveal novel targets for protecting or mitigating radiation injury of tissues and organs.

• International Journal of Advanced Culture Technology
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• 제6권3호
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• pp.27-36
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• 2018

This is qualitative research using grounded theory to examine the experiences that mothers of children with epilepsy can have. Data were collected through in-depth interviews, observation, and memo-taking with a total of 13 participants in this study-10 mothers taking care of children with epilepsy and 3 principal informants-and the data were analyzed using the method developed by Strauss and Corbin (1998). As a result of data analysis, 163 concepts, 26 subcategories and 8 categories were formed through open coding. Such categories were analyzed by the paradigm of the grounded theory, and as a result the experiences of the mothers of epileptic children were based on a causal condition of 'confrontation' and the central phenomenon of 'Wandering around the forest under a yoke'. The contextual conditions, which exerted influence on phenomena, were 'stigma cognition', 'personality traits' and 'health of children.' The action/interaction strategy selected by participants was 'Quietly pulling through: Bracing myself, Getting to know my enemy and myself, Taking care while hiding, Putting out one step at a time, Establishing a foothold. The intervening condition affecting action/interaction was 'the support system', and its result was 'watching.'

• 대한임상검사과학회지
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• 제44권4호
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• pp.178-183
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• 2012

We investigated the latest trend of u-Health and relations with clinical technologist. Since 2000, Korea has become an aging society. Korea will become an aged society by 2018, and it is expected to enter the ultra-high aged society by 2026. Increase in over 65 years population means that the desire of medical service and care demand for the elderly is greatly required. In addition, many predicted Korean national health insurance would falter financially. Medical suppression policies and regulations are also amended continuously. U-Health based on the IT industry and development of related technologies and industries contains the variety concepts of telemedicine, telehealth, e-health, u-healthcare and POCT. Especially, the use of POCT supplied quick clinical examination is extending steadily in medical center and hospital, which will generate the field friction between nurses and medical technologists. In the transition situation from provider-centric service to consumer-driven health care system, this study recommended the principal role and correspondence of clinical laboratory workers and offered information about changes in healthcare market and the basic concept of expert system, measurement and the diagnosis principle to clinical technicians throughout the investigation of the recent research and government policy trends.

• 경영과정보연구
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• 제8권
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• pp.147-166
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• 2002

This study investigated four universities in Busan and compared each other about the dimensions of service qality and relevant concepts. For empirical study, 288 respondents re sampled and six hypotheses are analyzed by using regression analysis and ANOVA. A survey was conducted with four university's students to see if there were significant differences in their perception(expectation, performance, perceived service quality, customer satisfaction, intention of repurchase) of a university administration service quality. The principal findings of this study are as follows: (1) A comparison of universities in terms of their expectations about university administration service revealed no differences, but performance revealed differences in specialization and reliability. (2) All of service dimensions, tangibles, reliability and specialization had significant impact on overall service quality. Specialization had the most significant impact on overall service Quality in A and D university, but tangibles had the most significant impact in B university. (3) Overall service Quality has a significant positive effect on customer satisfaction, but the degree of effect is different from each other. (4) Customer satisfaction has a significant positive effect on intention of repurchase, but the degree of effect is different from each other. In conclusion this study, however has a limitation about questionnaire, offers some strategic directions for developing the specific marketing strategies of university.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2008년도 추계학술대회B
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• pp.3181-3188
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• 2008

The supercritical $CO_2$ Brayton cycle energy conversion system is presented as a promising alternative to the present Rankine cycle. The principal advantage of the S-$CO_2$ gas is a good efficiency at a modest temperature and a compact size of its components. The S-$CO_2$ Brayton cycle coupled to a SFR also excludes the possibilities of a SWR (Sodium-Water Reaction) which is a major safety-related event, so that the safety of a SFR can be improved. KAERI is conducting a feasibility study for the supercritical carbon dioxide (S-$CO_2$) Brayton cycle power conversion system coupled to KALIMER(Korea Advanced LIquid MEtal Reactor). The purpose of this research is to develop S-$CO_2$ Brayton cycle energy conversion systems and evaluate their performance when they are coupled to advanced nuclear reactor concepts of the type under investigation in the Generation IV Nuclear Energy Systems. This paper contains the research overview of the S-$CO_2$ Brayton cycle coupled to KALIMER-600 as an alternative energy conversion system.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1998년도 제13차 학술회의논문집
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• pp.496-500
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• 1998

Not merely running at the designated constant speed as the classical cruise control, the adaptive cruise control (ACC) maintains safe headway distance when the front is blocked by other vehicles. One of the most essential part of ACC System is the range sensor which can measure the position and speed of all objects in front continuously, ignore all irrelevant objects, distinguish vehicles in different lanes and lock on to the closest vehicle in the same lane. In this paper, the hierarchical object recognition algorithm (HORA) is proposed to process raw scanning laser data and acquire valid distance to target vehicle. HORA contains two principal concepts. First, the concept of life quantifies the reliability of range data to filter off the spurious detection and preserve the missing target position. Second, the concept of conformation checks the mobility of each obstacle and tracks the position shift. To estimate and predict the vehicle position Kalman filter is used. Repeatedly updated covariance matrix determines the bound of valid data. The algorithm is emulated on computer and tested on-line with our ACC vehicle.

• 한국IT서비스학회지
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• 제7권4호
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• pp.45-60
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• 2008

Networked enterprise (NE) is an organization of independent companies that collaborate with each other temporary or permanently for accomplishing common goals. The USA and EU have been developing principal concepts, techniques, and solutions to enhance the competitiveness of traditional industries including small-and-medium enterprises (SMEs). In Korea, however, implementation as well as R&D of NE is very few, which we believe comes from lack of understanding on Its meaning and lack of effective information systems for it. This paper is to suggest an Enterprise Architecture (EA) framework or reference model of NE and an Information Technology Architecture (ITA) of NE. The EA framework will help stakeholder of NE (e,g., policy makers, members of NE, IT solution providers, and researchers) understand structural and behavioral characteristics of NE. The ITA will be used as a guideline of developing information systems for NE that is essential for spreading networked business models, The focus of this paper is not on logical-level design but on conceptual-level modeling of NE. As verification of the suggested framework and architecture is still required, so we'll apply them to various manifestations of NE, e.g., dynamic supply chain, vertical integration of extended enterprises, and P2P-style virtual enterprises.

• International Journal of Computer Science & Network Security
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• 제22권9호
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• pp.271-279
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• 2022

In the discipline of design science, the integration of cognitive, semantic, and affective elements is crucial in the conception and development of a product. Affective components in IT artefacts have attracted researchers' attention, but little attention has been given to Geographic Information Systems (GIS). This research was conducted to identify emotions in web-based GIS, and determine design influences on the emotions using Kansei engineering (KE). In the evaluation procedure, ten web-based GIS were used as specimens, and 20 Kansei words were used as emotional descriptors in the Kansei checklist. 50 participants were asked to rate their emotional responses towards the specimens on the Kansei checklist. Principal Component Analysis was used to discover the semantic structure of Kansei, in which dynamism and spaciousness were identified. Significant Kansei concepts were identified using Factor Analysis, in which dynamic & well-organized, refreshing, spacious, professional, and nautical-look were identified. Partial Least Square analysis has assisted the research in discovering the significant design influence to the Kansei. These findings provide designers and other stakeholders with valuable knowledge for strategizing future web-based GIS designs that incorporate user emotions.