• Journal of Plant Biology
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• 제15권1호
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• pp.33-41
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• 1972

Nine shrub layer communities under two relatively well conserved natural summer green forests in the central region of Korean Peninsula were studied for the pattern of stem distribution in terms of Greig-Smith's multiple split-plot experiment and for the association between the population of the two main species in terms of Kershaw's covariance analysis respectively. Four contiguous belt transects, $4{\times}64m size with 1{\times}1m$ basic unit, were set in each shrub layer communities. Significant primary clumps with $1{\times}1m or 1{\times}2m$ dimension wer observed consistently throughout the nine study sites. The primary clumps themselves were significantly distributed either regularly or at random. The association between the two principal species of each shrub layer is highly significantly either positive or negative in $1{\times}1m or 1{\times}2m$ dimension. As the plot size increases from $1{\times}1m to 8{\times}8m$ the associational trends were changed from negative to positive direction in one forests. But the change from positive to negative direction and the consistent negative association were also observed from the other forest. All of the association trends were observed only from $1{\times}1m to 4{\times}4m$ dimension. These results are suggestive that the distributional pattern of the shrub layer species under the summer green forest is simple mosaic fashioned with $1{\times}1m or 1{\times}2m$ dimension. The rest of the principal species are located in that matrix. The simple mosaic pattern of two principal species are located in that matrix. The simple mosaic pattern of two principal species seems to be controlled by change in micro-environmental pattern. Differences between the primary random group and clumped group among sites also suggest that competition exists for light or/and soil between primary clumped groups.

• 한국식품영양과학회지
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• 제33권5호
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• pp.797-802
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• 2004

L-Ascorbic acid (AsA), commonly known as vitamin C, which is one of the antioxidant vitamins, plays a role in cellular oxidant quenching. Some of the biochemical reactions in which it takes part have been traced through organ culture technique. But in cell cultured system, views on stimulatory and inhibitory action of AsA on cell growth are conflicting. Therefore, this study aimed to clarify the inhibitory action of high concentration AsA on the cell growth in Primary chondrocyte isolated from rat ribs. Cells were exposed to ascorbate at various concentrations. Supplement of AsA induced stimulation of cell growth in primary cultured cells of chondrocytes. Most remarkable stimulation of cell growth by AsA was found in primary cultured chondrocytes. However, it showed that they were dead in the medium which contained AsA at the concentration higher than 1.0 mM. This lethal effect of AsA causing the cell death was inhibited by the addition of catalase in the medium. This supposed that hydroxyl radical (ㆍOH) induced from $H_2O$$_2$ was actively cytotoxic agent. Based on the results, when AsA was added in medium at normal concentrations, the cell growth was stimulated by inducing the formation of extracellular matrix. On the contrary, if added in medium at excess concentrations, the cell growth was inhibited because $H_2O$$_2$ were generated from AsA in medium. Therefore, addition of AsA at the normal concentrations stimulates cell growth, but excess concentrations of AsA induces cell death.

• 한방재활의학과학회지
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• 제29권2호
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• pp.101-113
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• 2019

Objectives Bogol-tang has clinically been used to protect joint cartilage and to treat osteoarthritis. Our objective was to study the protective effect of Bogol-tang extract (BGT) in functional impairment, behavioral disorders, cartilage loss and pathological changes in a monoiodoacetate (MIA)-induced murine osteoarthritis (OA) model and interleukin (IL)-$1{\beta}$ -treated primary rat chondrocytes. Methods Mouse knee joints were injected with MIA, a chemical that inhibits glycolysis and causes joint inflammation and matrix loss. MIA-OA induced mice orally administered BGT or acetaminophen (AAP) for 18 days by daily. Primary rat chondrocytes were pretreated with BGT or dexamethasone (DEX) and followed by co-incubation with IL-$1{\beta}$ (10 ng/mL). Results In MIA-OA mice model, BGT led to delayed response on hot plate analysis, and suppressed the cartilage loss and damages in joint tissues. BGT suppressed the elevated levels of inflammatory mediators, nitrite and $PGE_2$, the gene expression of matrix degrading enzymes, and extracellular-signal-regulated kinases 1/2 and c-JunN-terminal kinase phosphorylation in IL-$1{\beta}$-treated primary rat chondrocytes. Conclusions Our results suggest that BGT improve the knee joint function and delay the cartilage damages by anti-nociceptive, anti-inflammatory and ant-catabolic effects, which indicate BGT could be a potential candidate for osteoarthritis treatment.

• 한국지능정보시스템학회:학술대회논문집
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• 한국지능정보시스템학회 1999년도 추계학술대회-지능형 정보기술과 미래조직 Information Technology and Future Organization
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• pp.121-130
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• 1999

The objective of this paper is to apply Extended AND-OR Graph (EAOG)-related techniques to extract knowledge from a specific problem-domain and perform analysis in complicated decision making area. Expert systems use expertise about a specific domain as their primary source of solving problems belonging to that domain. However, such expertise is complicated as well as uncertain, because most knowledge is expressed in causal relationships between concepts or variables. Therefore, if expert systems can be used effectively to provide more intelligent support for decision making in complicated specific problems, it should be equipped with real-time inference mechanism. We develop two kinds of EAOG-driven inference mechanisms(1) EAOG-based forward chaining and (2) EAOG-based backward chaining. and The EAOG method processes the following three characteristics. 1. Real-time inference : The EAOG inference mechanism is suitable for the real-time inference because its computational mechanism is based on matrix computation. 2. Matrix operation : All the subjective knowledge is delineated in a matrix form, so that inference process can proceed based on the matrix operation which is computationally efficient. 3. Bi-directional inference : Traditional inference method of expert systems is based on either forward chaining or backward chaining which is mutually exclusive in terms of logical process and computational efficiency. However, the proposed EAOG inference mechanism is generically bi-directional without loss of both speed and efficiency.

• 동의신경정신과학회지
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• 제34권4호
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• pp.359-368
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• 2023

Objectives: This study aims to establish a Korean medicine doctor's range of services in the dementia relief primary care system based on the previously developed dementia clinical practice guidelines (CPGs). Developing a dementia relief primary care Clinical Pathway (CP) can aid clinically when the Korean medicine primary care doctor conducts treatment. Methods: We analyzed Dementia Korean Medicine Primary Care Model Data and then applied CP Methodology to develop the configuration of the Korean Medicine Primary Care Model. For patients with Alzheimer's dementia (AD), vascular dementia (VD), and mild cognitive impairment (MCI), the Korean Medicine Primary Care Model focuses on improving cognitive function, everyday living abilities and easing symptoms through interventions described in CPGs. The contents of the draft model later include references to already-existing CPs. Results: The study sites were chosen as Korean medical clinics connected to primary care physicians in the dementia-friendly model. The CP used a time task matrix version to arrange the clinical chronology, which included all examinations, diagnoses, and treatment procedures, from the initial appointment to follow-ups and the end of therapy. Conclusions: It anticipates that Korean primary care doctors familiar with dementia can use the offered therapies for the first time by creating the dementia Korean medicine primary care model in this study. This is expected to maximize the range of medical services provided by Korean medicine and improve the standard of medical treatment.

• Journal of Microbiology
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• 제40권1호
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• pp.70-76
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• 2002

Proviral DNAs from HIV-1-infected CD4+ T cells (Molt/LAV cells) were amplified and detected in infected individual cells using polymerase chain reaction and in rifu hybridization. In this in situ PCR, three parameters were considered to achieve effective amplification and retention of amplificants inside the cells by making high molecular weight PCR products intracellularly, forming agarose matrix against the cells, and maintaining the appropriate PCR temperature profile. Over the cycles of ampliHcationl tailed primers with complementary overhanging sequences at their 5' sides manufactured high molecular weight products by using short primary products as a repeating unit. Agarose matrix could prevent the diffusion of the amplificants from the cells. Use of Thermanox coverslip inside the PCR tube offered target cells a similar temperature profile to that of conventional PCR in solution.

• 제어로봇시스템학회논문지
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• 제4권4호
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• pp.413-419
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• 1998

A novel order-reduction technique for model predictive control(MPC) is proposed based on the singular value decomposition(SVD) of a pulse response circulant matrix(PRCM) of a concerned system. It is first investigated that the PRCM (in the limit) contains a complete information of the frequency response of a system and its SVD decomposes the information into the respective principal directions at each frequency. This enables us to isolate the significant modes of the system and to devise the proposed order-reduction technique. Though the primary purpose of the proposed technique is to diminish the required computation in MPC, the clear frequency decomposition of the SVD of the PRCM also enables us to improve the robustness through selective excitation of frequency modes. Performance of the proposed technique is illustrated through two numerical examples.

• 대한기계학회논문집
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• 제17권7호
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• pp.1751-1760
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• 1993

The squeeze casting process is considered as an attractive way to form the primary product of near net shape metal matrix composites for wide use in automobile industry. To understand for infiltration limit in squeeze casting processes, the SAFFIL short fiber preform of volume fraction $10%{\sim}23%$ were fabricated by vaccum pumping and speed control press, and the optimal condition for fiber preform fabrication had been experimentally obtained. The composite materials were fabricated by forced infiltration of molten metals such as Al6061, Al7075, pure Al, AC8A, and Al2024. The infiltration distance and deformation of fiber preform are observed, and tensile strength were measured from at the room temperature.

• 한국공작기계학회논문집
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• 제15권2호
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• pp.93-98
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• 2006

This study provides a comprehensive experimental study on the dynamic characteristics of a flexible matrix composite(FMC) driveshaft. A primary objective is to verify the analytic results of the FMC drivetrain based on the equivalent complex modulus approach and the classical lamination theory. A test rig has been constructed, which consists of a FMC shaft, a foundation beam, bearings, external dampers and a driving motor. The frequency response functions and transient responses are obtained from the external excitation and the spin-up testings. It turns out that the analytic results are in good agreement with the experimental ones.

• ETRI Journal
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• 제36권4호
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• pp.545-553
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• 2014

This paper proposes an algorithm to sense orthogonal frequency-division multiplexing (OFDM) signals in cognitive radio (CR) systems. The basic idea behind this study is when a primary user is occupying a wireless channel, the covariance matrix is non-diagonal because of the time domain cross-correlation of the cyclic prefix (CP). In light of this property, a new decision metric that measures the power of the data found on two minor diagonals in the covariance matrix related to the CP is introduced. The impact of synchronization errors on the signal detection is analyzed. Besides this, a likelihood-ratio test is proposed according to the Neyman-Pearson criterion after deriving probability distribution functions of the decision metric under hypotheses of signal presence and absence. A threshold, subject to the requirement of probability of false alarm, is derived; also the probabilities of detection and false alarm are computed accordingly. Finally, numerical simulations are conducted to demonstrate the effectiveness of the proposed algorithm.