BACGROUND: To examine effect of omahwan(烏麻丸)-赤何首烏(Polygonum multiflorum THUNB.), 白何首烏(Cynanchum wilfordii H.), 黑芝流(Sesamum indicum L.)-on the aged human immune system a series of humoral immunological parameters was compared in aged female (age 60-70 years) before and after administration of omahwan(烏麻丸). METHODS: Peripheral blood was obtained from fifteen healthy young (age 20-29, mean=66.3) female volunteers. B cell, T cell(T cells, T helper, and T suppressor/ cytotoxic) subsets was examined with specific monoclonal antibodies and isotype controls, using dural color flow cytometer IL-2 was examined with ELISA kit RESULT: By comparing the immune characteristics of the younger and elder groups the total ratio of T-cell, CD8 T-cell and quantify of IL-2 was significantly lower while CD4/CDB ratio was considerably greater in the elder group. ( p(0.05, student t-test) After giving Omahwan for 30 days to the elder group, by comparing the ratio before and after Prescription the total T cell and CD8 T cell ratio was considerably greater after prescription (p(0.05, Paired t-test) The quantity of IL-2 tended to increase after prescription but has no statistical meaning. CONCLUSION: The results indicate that administration of Omahwan(烏麻丸) differentially affects various aspects of the immune system in aged human.
Journal of Korean Society of Industrial and Systems Engineering
/
v.42
no.4
/
pp.145-152
/
2019
All machines deteriorate in performance over time. The phenomenon that causes such performance degradation is called deterioration. Due to the deterioration, the process mean of the machine shifts, process variance increases due to the expansion of separate interval, and the failure rate of the machine increases. The maintenance model is a matter of determining the timing of preventive maintenance that minimizes the total cost per wear between the relation to the increasing production cost and the decreasing maintenance cost. The essential requirement of this model is that the preventive maintenance cost is less than the failure maintenance cost. In the process mean shift model, determining the resetting timing due to increasing production costs is the same as the maintenance model. In determining the timing of machine adjustments, there are two differences between the models. First, the process mean shift model excludes failure from the model. This model is limited to the period during the operation of the machine. Second, in the maintenance model, the production cost is set as a general function of the operating time. But in the process mean shift model, the production cost is set as a probability functions associated with the product. In the production system, the maintenance cost of the equipment and the production cost due to the non-confirming items and the quality loss cost are always occurring simultaneously. So it is reasonable that the failure and process mean shift should be dealt with at the same time in determining the maintenance time. This study proposes a model that integrates both of them. In order to reflect the actual production system more accurately, this integrated model includes the items of process variance function and the loss function according to wear level.
Journal of agricultural medicine and community health
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v.9
no.1
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pp.39-45
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1984
This research was done to gain the health information in one of the target areas(rural area) of the Korea University Community Health Project, and to improve and standardize the methodology of the health interview survey. There were two types of questions;one was the simple open-ended question and the other was check list in the interview survey for a total of 1,406 inhabitants. And so the result obtained from the above survey was analysed. The results as follows; 1) The morbidity rate in general was 11.2% by simple open-ended question and 32.5% by check list during recent 20 days in interview method. 2) Women had higher morbidity rate in both kinds of method. 3) The most prevalent diseases in the interview method using check list were the ones of the musculo-skeletal system and connective tissue (22.5%), and diseases of the respiratory system (19.8%) and digestive system (13.7%) were in order of frequency. 4) By the position in the family, housewives had highest morbidity rate in the interview method unrespectedly, and the reason seemed that the respondents were houseweives themselves and the morbidity rate was the one by spell not by person. But morbidity rate by the socio-economic status had no significant difference in both methods. 5) The agreement rate on simple open-ended question and check list was 72.5%, but if limiting respondents themselves only, the rate was falled to 54%. 6) The morbidities were diverse in the review of the results of previous morbidity surveies, but the morbidity rate was higher and less variable in case of using check list and getting the replies individually than using simple open-ended question and proxy respondents.
This study was conducted to identify the problems related to operation of the committee system in university hospitals and to propose the direction for reforming it. Data were collected by surveying 138 working-level administration managers of committees from 12 university hospitals in Seoul in October, 1995. The results were as follows: 1. The purposes of the committee were to promote the reasonable dicision making in the hospitals, to satisfy the requirement of Hospital Accreditation Program and, to execute the administrational instructions in due order. The sort of job which was charged of chairmen and the majority of committee member was doctor. 2. The committees which were to be held the meeting frequently in a year were general management committees(8.25 times/year). But in case of operation rate, medical care-related committees showed the most frequent meeting(90.15%). Most of committees made the regulations and reported the results of their meeting to the CEO of their hospitals by written documents. 3. Most doctors thought the medical care-related committees useful. Medical technicians regarded education and research-related committees as useful, while administrators favored the general management committees. 4. The factors related to the perceived performance of the committee were the kind of job, the class of job and the kind of committee. Also, the perceived performance of the committee was positively related to the usefulness in efficient management of work, and negatively to uncertainties in responsibility and a nominal role of the committee. 5. Most of the respondnts thought that the concern of the top manager about the committee was the most important factor for the improvement of committee system at hospitals. They also regarded that formalization of the objectives and regulation rule and composition of committees with members which work in various fields as essential. Further studies on the organizational and operational cjharacteristics which include general hospitals in various areas are required.
At the preliminary survey of Seosan demonstration project for integration of family planning and maternal and child health service, 6 questions about morbid conditions of all household members were included. Definition of morbid condition used at the survey was self-conceived physical or mental infirmity which had been caused by diseases or accidents, resulting in obstacles to ordinary daily life for past 30 days. Analyzing those morbidity data, the following results were obtained. 1. The morbid person rate was 192.2 per 1,000 persons and the morbidity rate 214.2 per 1,000 persons. 2. The percentage of household which had at least one morbid person was 61.9% and average number of morbidity per one household was 1.1. 3. Analyzing the 1st morbid condition of the total 4,433 morbid persons, morbidity rate of male was 194.6 per 1,000 persons and that of female was 189.8 per 1,000 persons. 4. The highest age specific morbidity rate was that of $0{\sim}4$ years of age, and it was 304.3 per 1,000 persons. The lowest was that of $10{\sim}14$ years of age and the rate of 93.8 per 1,000 persons. 5. The following was the order of five major diseases which were classified according to 17 International Classification of Diseases. (1) Symptoms and Ill defined conditions : 17.3% (2) Disease of the Digestive system : 15.7% (3) Infections and Parasitic disease 14.3% (4) Disease of the Respiratory system : 13.7% (5) Disease of the Nervous system and sense organs : 9.4% 6. 30 leading morbid conditions were described in Table III-2 and which composed 70.6% of total morbid conditions. 7. The percentage of the morbid conditions of which duration was longer than 90 days was 40.5%. 8. Of the total 4,433 morbid persons, 4,394 morbid persons responded for the morbid condition management method. Of those, Hospital & clinic (35.3%), drug store (40.0%), herb drug store (3.6%), health center (2.2%) ware selected for the 1st place or method for management morbid condition, and 18.0% did not search for morbid condition management.
Kim Sung-Il;Moon Jin-Young;Kim Kap-Sung;Kim Doo-Hie;Nam Kyung-Soo;Lim Jong-Kook
Journal of Society of Preventive Korean Medicine
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v.1
no.1
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pp.48-54
/
1997
Scutellariae radix, has been used as a natural drug for fever, inflammation, cataract, and liver disease in traditional medicine. This study was performed in order to investigate the antioxidative effects of Scutellariae radix aqua-acupuncture solution (SRAS) on lipid peroxidation by free radicals. Lipid peroxidation levels were determined by TBA method during the autoxidation of linoleic acid. In this linoleic acid autoxidation system, SRAS markedly exhibited antioxidant activity, which inhibited 89% of linoleic acid peroxidation. SRAS showed scavenging effects on ${\alpha},{\alpha}-diphenyl-{\beta}-picrylhydrazyl$(DPPH) radical, inhibited superoxide generation in xanthine-xathine oxidase system, and also inhibited lipid peroxidation of rat liver tissue by hydroxyl radical derived from $H_2O_2-FE^{+2}$ system. These effects were similar to those of $dl-{\alpha}-tocopherol$, BHA and BHT. In addition, SRAS protected the cell death induced by ter-butyl hydroperoxide (t-BHP) and significantly increased cell viability in the normal rat liver cell (Ac2F). On the basis of these results, it is suggested that SRAS might play a protective role in lipid peroxidation by free radicals.
Fiscal crisis in the medical insurance has put the pressure upon hospitals by increasing the rate of curtailment, since the implementation of the separation between prescription and dispensing of Drug. The purpose of this study is to analyze the curtailment for antibiotics, injected drug and other drugs expenditure before and after the system of separation between prescribing and dispensing. Data were gathered from 13 general hospitals and used for analysis of trends on antibiotics and injected drug expenditure, and curtailment in 2000-2001 at three months intervals. The results were as follows; The curtailment rate of antibiotics expenditure has been increased in outpatient and inpatient since 2000. The curtailed antibiotics cost and injected drug cost in outpatient under the prescription within the hospital and in inpatient increased. The ratios of curtailment versus expenditure had increased in antibiotics, injected drugs, anticancer drugs, antiulcer drugs, albumine, antiinflammatory drugs. These results suggest that claim review system in social health insurance were over-focused mainly to control the cost and it might to impede the validity of claim review function in health insurance system. Therefore, it's needed to develope the scientific and reasonable parameter & criteria for claim review of drug expenditure.
The objectives of this study are (i) to review current situations and problems of the occupational health care system with emphasis on reforming the organizations and services, (ii) to find out a disirable occupational health system model based on integration of the occupational health system and the general health system, and finally, (iii) to suggest policy implications in occupational health services in the light of objectives of the newly emerging national health insurance reform in Korea. The major policy implications of this study are as follows: 1. In the long-run, within the occupational health system, preventive occupational health services such as employees' physical check-up, working environment examination, etc should financially be integrated with industrial accident compensation insurance. Currently separately paying expenses for each different category of services by the owner of an enterprise should be disbursed once through the payment of contributions of industrial accident compensation insurance. And then, it is necessary to strengthen and expand the role and function of industrial accident compensation insurance to cover preventive occupational health services. 2. The occupational health system should be integrated with general health system for its effective management. For the short-term policy, it is necessary to eliminate fiscal and access barrier between industrial accident compensation insurance and national health insurance by means of ex post facto settlement of accounts. The duplication of employees' physical check- ups between under the health insurance program and under the industrial health services must be coordinated in a manner either through mutual authorization by the two parties concerned or through merge into the health insurance. 3. The intent of current employees' physical check-up system focused on detection of occupational diseases, should be converted to an idea of medical surveillance system or biological moritoring system. The introduction of medical surveillance or biological monitoring system is a necessary condition to build a positive, effective and inexpensive occupational health care system.
Background : The system for collecting and managing the terminologies of Korean oriental medicine is essential to facilitate researches of developing intelligent information architecture based on ontology. Objectives : The purpose of this paper is to develop system for collecting and managing system for terminologies of Korean oriental medicine. Methods : First we defined roles of users used in this system, and define the system workflow based on them. Then we developed web-based collecting and managing system in which multiuser can work simultaneously, and it is compose of relational database system. Results : The terminologies of Korean Oriental Medicine can be efficiently collected, purified, inspected, and utilized by using proposed system. Conclusions : The system, proposed in this paper, can be used the whole field of oriental medicines for basic technology and has great contributions to make intelligent information architecture of oriental medicine based on ontology concept.
The objectives of the study were to provide the basic informations needed in the development of balanced medical services throughout the nation. As the national health care system was expanding rapidly along with the economic growth, quantitative re-evaluation of the system is of great need. For that reason, characteristics of the admitted patients were analyzed for the case-mix and patients' flow within and through regions. Materials were 421,530 cases of inpatients, who were reported through Korea Medical Insurance Corporation(KMIC) for insurance claim, during the period of March 1, 1985 through February 28, 1987. Korean Diagnosis Related Groups(K-DRGs) classification system was adopted for the study of case-mix and 189 cities and counties were classified into 5 district groups by factor analysis results of K-DRGS. The major findings of this study were as follows ; 1) Factor analysis of case-mix, employing K-DRG system, revealed 5 distinct funtional district groups. Group A(18 districts) was prominent for tertiary medical care. In group B(36 districts), rather simple procedures were prevalent. Group C(26 districts) was distinctive for the medical care of well organized internal medicine practices with qualified clinical laboratories. Group D(17 districts) was characterized by relatively high balanced medical care. Group E (92 districts) was with very low level of medical care. 2) Analysis of the case-flow through the districts showed 3 types of flow patterns : inflow, outflow, and balanced types. Inflow type of case-flow was found in Group A, C and D while Group B and E showed outflow type. Inflow was most prominent in Group A and Group E was of typical outflow type. Group B was consistently the outflow type except for Major Diagnostic Category XX regardless of the disease treaters, but Group C and D were inflow or outflow types according to the disease tracers.
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