• Biomolecules & Therapeutics
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• 제13권2호
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• pp.84-89
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• 2005

The purpose of this study was to characterize the putative anxiolytic-like effects of the aqueous extract of the root of Polygala tenuifolia ( AEPT) using an elevated plus maze (EPM) and hole-board apparatus in mice. The AFPT was orally administered at 50, 100, 200 or 400 mg/kg to ICR mice, 1 h before the behavioral evaluation in the EPM respectively. Control mice were treated with an equal volume of saline, and positive control mice with buspirone (2 mg/kg). Single treatments of the AEPT significantly increased the percentage of time spent and arm entries into the open arms of the EPM vedrsus saline controls (P<0.05). Moreover, there were no changes in the locomotor activity and myorelaxant effects in any group compared with the saline controls. In the hole-board test,single treatments of the AEPT (200 and 400 mg/kg) significantly increased the number of headdips versus saline controls (P<0.05). In addition, the anxiolytic-like effects of the AEPT were blocked by WAY 100635(0.3mg/kg, I.p), a5-$HT_{1A}$ receptor antagonist not by flumazenil, a $GABA_{A}$ antagonist. These results indicate that P. tenuifolia is an effective anxiolytic agent, andsuggest that the anxiolytic-like effects of P. tenuifolia is mediated via the serotonergic nervous system.

• Natural Product Sciences
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• 제15권3호
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• pp.115-120
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• 2009

Woohwangcheongsimwon (WHCSW) is a traditional oriental medicinal fomula which has been clinically used for treating strokes, palpitation, loss of consciousness and anxiety. The purpose of this study was to characterize the putative anxiolytic properties of WHCSW using an elevated plus-maze (EPM) and hole-board test. Control mice were orally treated with an equal volume of vehicle (10% Tween 80 solution), and positive control mice were treated with diazepam (1 mg/kg, i.p.). In the EPM test, WHCSW significantly increased the percentage of time-spent in the open arms (200 mg/kg, P < 0.05) and the percentage of open arm entries (200 and 400 mg/kg, P < 0.05). WHCSW also significantly increased the number of head-dips in the hole-board test (200 mg/kg, P < 0.05). In addition, the anxiolytic properties of WHCSW examined in the EPM test were inhibited by flumazenil (10 mg/kg, i.p.), a GABA$_A$ antagonist. However, no changes in spontaneous locomotor activity or myorelaxant effects were observed versus 10% Tween 80 controls. These results suggested that WHCSW is an effective anxiolytic agent, and that its anxiolytic effects are mediated via GABA$_A$ receptors.

• 한국의류학회지
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• 제13권1호
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• pp.49-58
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• 1989

A clothing-erogonomics study was performed to investigate the difference of the upper arm skin skin surface and the relationship among the three aspects of upper arm (height of sleeve rap, sleeve width and armhole girth) by changing arm movements. Plaster cast was used for this experimental research. Arm movements consist of 9 types; just carmly standing on ($0^{\circ}$), and each 4 types ($45^{\circ},\;90^{\circ},\;135^{\circ},\;180^{\circ}$) to the vertical direction in front and in side. The results were as follows; 1) As the arm-movement angle increased, the height of sleeve cap decreased and that ratio was largest in the portion A-B3. 2) The steeve width was enlarged with the increment of movement angle in all portions of upper arm except B1-B5. 3) As increasing the movement angle, the whole armhole girth decreased and the ratio o(front armhole girth (F-A) was larger than that of back. 4) In the vertical direction in front, the height o( the sleeve caps was larger, the sleeve widths were smaller than in the vertical direction in side in all movement types, but there was no significant difference in arm-hole girth between the two cases. 5) There were significantly negative relationships between measurements in height of sleeve cap and those in sleeve width, and also between those in height of sleeve cap and in arm-hole girth. And significantly positive relationships were found between neasurements in height of sleeve cap and those in arm-hole girth.

• 한국재료학회지
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• 제29권3호
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• pp.155-159
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• 2019

Surface plasmon resonance is the resonant oscillation of conduction electrons at the interface between negative and positive permittivity material stimulated by incident light. In particular, when light transmits through the metallic microhole structures, it shows an increased intensity of light. Thus, it is used to increase the efficiency of devices such as LEDs, solar cells, and sensors. There are various methods to make micro-hole structures. In this experiment, micro holes are formed using a wet chemical etching method, which is inexpensive and can be mass processed. The shape of the holes depends on crystal facets, temperature, the concentration of the etchant solution, and etching time. We select a GaAs(100) single crystal wafer in this experiment and satisfactory results are obtained under the ratio of etchant solution with $H_2SO_4:H_2O_2:H_2O=1:5:5$. The morphology of micro holes according to the temperature and time is observed using field emission - scanning electron microscopy (FE-SEM). The etching mechanism at the corners and sidewalls is explained through the configuration of atoms.

• 상하수도학회지
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• 제12권1호
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• pp.88-95
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• 1998

The Electron/Hole Pair is generated when the Activation Energy produces by Ultraviolet Ray illumination to the Semiconductor. And $OH^-$ ion produces by Water Photo-Cleavage reacts with Positive Hole. As a result, OH Radical acting as strong oxidant is generated and then Photocatalytic Oxidation Reaction occurs. The Photocatalytic Oxidation can oxidize the chlorophenol to Chloride and Carbon Dioxide easier, safer and shorter than conventional Water Treatment Process With the same degree of chlorination, the $Cl^-$ ion at para (C4) position is most easily replaced by the OH radical. And then, the blocking effect of $OH^-$ ion between the $Cl^-$ ions and $Cl^-$ ions at symmetrical location is easily replaced by the OH radical. For mono-, di-, tri-chlorophenols, there is no obvious difference in decomposition rate, decomposition efficiency and completeness of the decomposition reaction except for 2,3-dichloropheno, 2,4,5-, 2,3,4-trichlorophenol. The decomposition efficiency is higher than 75% and completeness of the decomposition reaction is higher than 70%. Therefore, continuous flow photocatalytic reactor is promising process to remove the chlorinated aromatic compounds which is more toxic than non-chlorinated aromatic compound.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제9권11호
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• pp.4644-4661
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• 2015

Wireless sensor networks are often organized in the form of clusters leading to the new framework of WSN called cluster or hierarchical WSN where each cluster head is responsible for its own cluster and its members. These hierarchical WSN are prone to various routing layer attacks such as Black hole, Gray hole, Sybil, Wormhole, Flooding etc. These routing layer attacks try to spoof, falsify or drop the packets during the packet routing process. They may even flood the network with unwanted data packets. If one cluster head is captured and made malicious, the entire cluster member nodes beneath the cluster get affected. On the other hand if the cluster member nodes are malicious, due to the broadcast wireless communication between all the source nodes it can disrupt the entire cluster functions. Thereby a scheme which can detect both the malicious cluster member and cluster head is the current need. Abnormal energy consumption of nodes is used to identify the malicious activity. To serve this purpose a learning based energy prediction algorithm is proposed. Thus a two level energy prediction based intrusion detection scheme to detect the malicious cluster head and cluster member is proposed and simulations were carried out using NS2-Mannasim framework. Simulation results achieved good detection ratio and less false positive.

• Journal of Electrochemical Science and Technology
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• 제10권3호
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• pp.271-275
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• 2019

Anodic $TiO_2$ nanotubes were simultaneously grown and doped with $RuO_2$ by single-step anodization in a negatively-charged $RuO_4{^-}$ precursor. Subsequently, a high positive voltage was imposed on the nanotubes in an $F^-$-based electrolyte (a process referred to as potential shock), which led to the formation of a through-hole $RuO_2$-doped $TiO_2$ nanotube membrane without significant loss of the $RuO_2$ catalyst. XPS results confirmed that the doped Ru metal was converted into $RuO_2$ as the potential shock voltage increased. Further increases in the potential shock voltage led to the formation of $RuO_x/Ru$ in the $TiO_2$ nanotubes. All of our results clearly showed that a through-hole catalyst-doped $TiO_2$ nanotube membrane can be produced by a sequence consisting of single-step anodization and the potential shock process.

• 한국전기전자재료학회논문지
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• 제37권3호
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• pp.309-313
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• 2024

The key to determining the lifetime of OLED device is how much brightness can be maintained. It can be said that there are internal and external causes for the degradation of OLED devices. The most important cause of internal degradation is bonding and degradation in the excited state due to the electrochemical instability of organic materials. The structure of OLED modeled in this paper consists of a cathode layer, electron injection layer (EIL), electron transport layer (ETL), light emission layer, hole transport layer (HTL), hole injection layer (HIL), and anode layer on a glass substrate from top to bottom. It was confirmed that the temperature generated in OLED was distributed around the maximum of 343.15 K centered on the emission layer. It can be seen that the heat distribution generated in the presented OLED structure has an asymmetrically high temperature distribution toward the cathode, which is believed to be because the sizes of the cathode and positive electrode are asymmetric. Therefore, when designing OLED, it is believed that designing the structures of the cathode and anode electrodes as symmetrically as possible can ensure uniform heat distribution, maintain uniform luminance of OLED, and extend the lifetime. The thermal distribution of OLED was analyzed using the finite element method according to Comsol 5.2.

• 한국컴퓨터정보학회논문지
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• 제14권5호
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• pp.65-75
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• 2009

IT의 발전으로 많은 컴퓨터 사용자들이 인터넷 사용을 생활화하고 있다. HTML 기술을 이용한 웹 기술의 발전은 현대인들의 정보를 빠르고 쉽게 공유할 수 있도록 하고 있으며, 그 이용이 기하급수적으로 증가하고 있는 추세이다. 그러나 그에 따른 부작용으로 중요 시스템에 대한 정보 유출, 전산망 침해 등과 같은 침입 행위 또한 빠른 속도로 증가하고 있다. 이에 본 논문에서 제안하는 공격 트래픽 탐지 기법은 전통적인 네트워크기반 공개 침입탐지시스템인 Snort 탐지한 공격 트래픽 중 false positive 가능성이 있는 패킷을 Nmap 정보를 이용하여 필터링하고, nessus 취약점 정보를 이용하여 2차 필터링을 실시한 후, 운영체제의 적합성, 시그너처 위험도, 보안 취약점을 고려하여 상관성 분석을 최종적으로 실시하여 false positive 경고 메시지를 줄이고 false positive에 의한 오류를 최소화하여 전체적인 공격 탐지 결과를 높였다.

• 한국정보전자통신기술학회논문지
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• 제16권4호
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• pp.180-186
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• 2023

본 논문은 4세대 VNAND 공정으로 만들어진 고전압 SiO2 절연층 nMOSFET의 n⁺ 및 p⁺ poly-Si 게이트에서의 positive bias temperature instability(PBTI) 열화에 대해 비교하고 각각의 메커니즘에 대해 분석한다. 게이트 전극 물질의 차이로 인한 절연층의 전계 차이 때문에 n⁺/nMOSFET의 열화가 p⁺/nMOSFET의 열화보다 더 클 것이라는 예상과 다르게 오히려 p⁺/nMOSFET의 열화가 더 크게 측정되었다. 원인을 분석하기 위해 각각의 경우에 대해 interface state와 oxide charge를 각각 추출하였고, 캐리어 분리 기법으로 전하의 주입과 포획 메커니즘을 분석하였다. 그 결과, p⁺ poly-Si 게이트에 의한 정공 주입 및 포획이 p⁺/nMOSFET의 열화를 가속시킴을 확인하였다.