• International Journal of Contents
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• v.8 no.4
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• pp.74-77
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• 2012

Radiation has been an effective tool for treating cancer for a long time. Radiation therapy induces DNA damage within cancer cells and destroys their ability to reproduce. Radiation therapy is often combined with other treatments, like surgery and chemotherapy. Here, we describe the effects of radiation and histone deacetylase inhibitor, Trichostain A, on cell cycle regulation in hepatoma cells. The combinatorial treatment of radiation and Trichostain A induced cell cycle arrest and thereby increasing the hepatoma cell death. Furthermore, the regulatory effects of radiation and Trichostatin A on cell cycle applied in cell type specifically. These results suggest that the treatment of radiation and Trichostatin A may play a central role in hepatoma cell death and might be a good remedy to improve the efficiency of radiation therapy.

• 한국전산유체공학회:학술대회논문집
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• 1998.05a
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• pp.190-201
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• 1998

The numerical methodology for computing the impact forces of the water entry bodies has been developed. The present method assumed the impact occurs within a very short time interval and the viscous effects do not have time enough to play a significant role in the impact forces, that is, the flow around a water-entry object was assumed as an inviscid potential flow and is solved by the source panel method. The elements fully submerged into the water are routinely treated, but the elements intersected with the effective planar free surface are redefined and reorganized to be amendable to the source panel method. To validate the present code, it has been applied to disk and ogive model and compared with experimental data. Good agreement has been obtained.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.179.2-179.2
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• 2014

Carbon nanotubes (CNT)-metal contacts play an important role in nanoelectronics applications such as field-effect transistor (FET) devices. Using Al and (10,0) CNT, we have recently showed that the CNT-metal contacts mediated via topological defects within CNT exhibits intrinsically low contact resistance, thanks to the preservation of the sp2 bonding network at the metal-CNT contacts.[1] It is well-established that metals with good wetting property such as Pd consistently yield good contacts to both metallic and semiconducting CNTs. In this work, the electronic and charge transport properties of the interfaces between capped CNT and Pd will be investigated based on first-principles computations and compared with previous results obtained for the Al electrodes.

• Proceedings of the KIEE Conference
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• 2002.11b
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• pp.206-208
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• 2002

Distributed generation (DG) is predicted to play an increasing role in the electric power system of the near future. Distributed generation is by definition that is of limited size (roughly 10MW or less) and interconnected at the substation, distribution feeder or customer load levels. The effects of generation sources within a distribution network on the system losses are investigated in this paper. WLAV state estimation is performed with the composite distribution system containing DG. Simulations with test cases are performed and the results are presented, using IEEE34 bus radial distribution system.

• Journal of Korean Society on Water Environment
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• v.23 no.6
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• pp.872-880
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• 2007

For effective management of sediment-related diffuse pollution, it is of utmost importance to estimate spatial variation of sediment transport processes within a catchment. A mathematical model can play a critical role in estimating sediment transport processes at the catchment scale provided that the model structure is appropriate for representing major sediment transport processes of the catchment of interest. This paper introduces a distributed catchment model River Basin Water Quality Simulator (RBWQS) and presents some results of its application to a small rural catchment in Korea. The model has been calibrated and validated for a wet period using hourly hydrographs and sediment concentrations observed at the catchment outlet. Based on the model simulation results, the spatial variation of sediment transport processes across the catchment and the effects of paddy fields and small reservoirs on hydrology and sediment transport have been analyzed at the catchment scale.

• Research in Mathematical Education
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• v.15 no.2
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• pp.141-158
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• 2011

In recent years, an increasing number of viewpoints hold that students should be engaged in a learning environment where understanding and knowledge transfer take place. This study introduces Mathematics Created by You (MCY)-mentoring program, which allows students to construct artefacts that are required to learn. This program is online-based and so can be shared by several people and mathematics leaning takes place through interactions within this carefully designed environment. Also, MCY intends to provide students a series of sequential activities related to creative play, creative learning and creative inquiry based on a Constructive and interactive environment. Furthermore, a creative activity- constructing a creative product using building blocks- was presented as an example. Finally, we investigate the pedagogical implications and suggest directions for the further development.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.30 no.9 s.252
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• pp.891-897
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• 2006

The SRS method is applied to a turbulent flame with radiation/turbulence interaction to invert the temperature and concentration profile. The flame is conditioned as optically thin per each fluctuation length and the flame spectral intensity is measured for inversion. From inversion result, we find that SRS can successfully invert the coupled temperature/concentration fluctuation amplitudes. For two cases of experiments, inverted values are within approximately 1% over the full range of fluctuation amplitude. However, SRS cannot find the detailed local fluctuation parameters such as pattern and phase, etc. as far as they do not affect the resulting radiation intensity. Important available parameters are the mean temperature and the temperature fluctuation amplitude. The radiation/turbulence interaction effect is verified to play an important role in the radiation.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.17 no.3
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• pp.209-219
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• 2013

The present paper deals with the extension of AUSMPW+ scheme into two-fluid model for multiphase flow. AUSMPW+ scheme is the improvement of a single-phase AUSM+ scheme by designing pressure-based weighting functions to prevent oscillations near a wall and shock instability after a strong shock. Recently, Kitamura and Liou assessed a family of AUSM-type schemes with two-fluid model governing equations [K. Kitamura and M.-S. Liou, Comparative study of AUSM-Family schemes in compressible multi-phase flow simulations, ICCFD7-3702 (2012)]. It was observed that the direct application of the single-phase AUSMPW+ did not provide satisfactory results for most of numerical test cases, which motivates the current study. It turns out that, by designing pressure-based weighting functions, which play a key role in controlling numerical diffusion for two-fluid model, problems reported in can be overcome. Various numerical experiments validate the proposed modification of AUSMPW+ scheme is accurate and robust to solve multiphase flow within the framework of two-fluid model.

• The Mathematical Education
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• v.31 no.2
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• pp.121-132
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• 1992

The pointwise convergence define the relation-ship between the mesh-size and the tolerance. This will play an important role in improving quality of finite element approximate solution. In this paper, We evaluate the convergence on a certaon unknown point with a 1-irregular mesh refinement. This m that the degree of freedom is minimized within a tolerance.

• Genomics & Informatics
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• v.7 no.2
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• pp.111-121
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• 2009

Cell membrane proteins play crucial roles in the cell's molecular interaction with its environment and within itself. They consist of membrane-bound proteins and many types of transmembrane (TM) proteins such as receptors, transporters, channel proteins, and enzymes. Membrane proteomes of cellular organisms reveal some characteristics in their global topological distribution according to their evolutionary positions, and show their own information transfer complexity. Predicted transmembrane segments (TMSs) in membrane proteomes with HMMTOP showed near power-law distribution and frequency characteristics in 6-TMS and 7-TMS proteins in prokaryotes and eukaryotes, respectively. This reaffirms the important roles of membrane receptors in cellular communication and biological evolutionary history.