• 한국약용작물학회:학술대회논문집
• /
• 2010.10a
• /
• pp.439-440
• /
• 2010

• The Korean Journal of Ecology
• /
• v.17 no.4
• /
• pp.485-499
• /
• 1994

This study was focused on the effect of the altitude on the geographical variations of germination characteristics in the populations of Plantago asiatica L. distribute in Mt. Chiri. There was a significant difference among the 14 groups in the phenological pattern in relation to altitudes. When the altitude becomes higher, the thermal time which was required for 10 to 80% germination rate showed higher and wider distribution. On the other hand, the germination response of increasing temperature (IT) and secreasing temperature (DT) regime was classified into 3 group. The first group was the spering germination type. This group showed that the IT regime hadhigher germination rate than that of the DT regime, and was distributed in Macheon(300m) and Packmudong (500m). The second was the spring-fall germination type which was distributed in Hadong (900m) and Saemt대 (1100m). This group also showed higher germination rate in the IT regime, but the difference of the germination rate between IT and DT regime was less than that in the first group (the spring type). The third group was the early fall germination type which was found in the Nogodan (1507m), Changetomok (1750m) and Cheonwangbong (1915m). The germination rate of this group showed almost 100% similarity between IT and DT regime. These data suggested that the geographical varations of germination characteristics within species was an important ecological strategy for the survival from severe environmental conditions.

• The Korea Journal of Herbology
• /
• v.29 no.4
• /
• pp.77-82
• /
• 2014

Objectives : The effects of ethanol extract of Plantago asiatica L. were investgated on adipocyte differentiation, lipopogenesis, lipolysis and apoptosis using differnentiated 3T3-L1 adipocytes. Methods : Plantago asiatica L. was extracted with ethanol (CCE). We carried on MTT assay for cell proliferation, Oil Red O staining for determination of cell differentiation and intracelluar adipogenesis. TUNEL staining assay for cell apoptosis, and Western blot analysis for measurement of pAMPK and pACC, $C/EBP{\alpha}$, $PPAR{\gamma}$ protein expressions were performed. Results : The addition of CCE up to 0.2 mg/ml into cell culture media showed no cytotoxicity. Treatment of 0.2 mg/ml CCE significantly inhibited differentiation in 3T3-L1 preadipocytes. Lipid accumulation of the CCE treated cells was decreased compared with that of control. Induction of cell apoptosis was increased in CCE treated cells compared with that of control. AMPK and ACC levels of the cells with 0.2 mg/ml CCE were led to phosphorylation and also expressions of $C/EBP{\alpha}$ and $PPAR{\gamma}$, as adipogenic transcription factors, were suppressed compared with those of control. Conclusions : Taken together, these results provide evidence that CCE has a regulatory role in lipid metabolism that is related to differentiation into adipocytes, adipogenesis and apoptosis.

• The Korean Journal of Ecology
• /
• v.9 no.1
• /
• pp.91-101
• /
• 1986

To investigate the distribution of Plantago asiatica Linne, almost, restricted on the road-side, the plant growth analyzed by experimental cultivation under the condition of tread-pressure; 10 times/day (7.33kg/$cm^2$ ), 20 times/day (12.27kg/$cm^2$), 30 times/day (20.05kg/$cm^2$ ) and the control plot (1.68kg/$cm^2$ ). The matter production in the 10-time-per-diem plot (7.33kg/$cm^2$ ) of tread-pressure howed more large value than that inthe control one (1.68kg/$cm^2$ ) and those in the 20-0time-per-diem plot (12.27kg/$cm^2$ ) and the 30-time-per-diem one (20.05kg/$cm^2$ ) small values than that of the control plot. Especially, the growth of roots and spikes was extremely repressed. The number of leaves, scapes and lateral buds tend to increase in the tread-pressure of 20 times/day (12.27kg/$cm^2$ ) and 30 times/day (20.05kg/$cm^2$ ). The water contents of roots along the increase of tread-pressure to continuosly decreased. By the increase of tread-pressure, T/R ratio and C/F ratio their group decreased. The plant growth (7.33kg/$cm^2$ ) in the 10-time-per-diem plot increased more than that in the control one is regarded as the effect of tread-pressure affection on the road-side distribution of this plant.

• Korean Journal of Pharmacognosy
• /
• v.38 no.4
• /
• pp.376-381
• /
• 2007

Seven compounds were isolated from the MeOH extract of the seeds of Plantago asiatica L. and their structures were identified as ${\beta}-sitosterol$ (1), (24R)-6${\beta}$-hydroxy-24-ethyl-cholest-4-en-3-one (2), acteoside (3), geniposidic acid (4), 1-octen-3-ol 3-O-${\beta}$-D-xylopyranosyl$(1{\rightarrow}6)-{\beta}-D-glucopyranoside$ (5), plantainoside D (6) and plantamajoside (7) on the spectroscopic analysis. Among them, $(24R)-6{\beta}$-hydroxy-24-ethyl-cholest-4-en-3-one (2) and 1-octen-3-ol 3-O-${\beta}$-D-xylopyranosyl ($1{\rightarrow}6)-{\beta}-D-glucopyranoside$ (5) were first isolated from this plant. Among them, geniposidic acid (4) showed the most potent inhibitory effect on melanogenesis, with inhibition rate of 41%.

• Korean Journal of Medicinal Crop Science
• /
• v.7 no.2
• /
• pp.143-146
• /
• 1999

The cytotoxicity-guided fractionation of the seed of Plantago asiatica extracts led to the isolation of four compounds, responsible for the cytotoxicity against four human tumor cell lines, i. e., A431 (Human Epidermoid carcinoma), KHOS-NP (Human Osteosarcoma). SNU-1 (Human stomach carcinoma), SNU-C4 (Human large intestine carcinoma). The structure were elucidated by the phsyco chemical data: ${\beta}-sitosterol(C1)$, $cholest-5-en-3{\beta}-ol(C2)$, rutin(C3), $coumarin-7-O-{\beta}-glucopyranoside(C4)$. $IC_{50}$ values of compound C2 were 14.6, 13.5, 10.3, 17.8 ${\mu}g/ml$, and compound C3 and C4 showed activity, having $IC_{50}$ values ranging from 10.3 to 20.14 ${\mu}g/ml$.

• The Korean Journal of Mycology
• /
• v.13 no.1
• /
• pp.49-51
• /
• 1985

Mycoplasma-like organisms (MLO) were identified from three plants. The disease symptoms show stunting, yellowing and witche's broom on Cnidium officinale Makino collected from Ulreung Island, Bupleurum falcatum L. collected from Jangsu, and Plantago asiatica L. collected from Daegwanreung. The particles of MLO were observed in the phloem tissues by a Hitachi Hu-11E electron microscope. C. officinale infected with MLO was frequently observed in Ulreung Island.

• Food Science and Preservation
• /
• v.18 no.2
• /
• pp.212-218
• /
• 2011

The purpose of this study is to determine the possibility of using Plantago asiatica as natural health food source. To accomplish this purpose. the contents of proximate and anti oxidative nutrients of P. asiatica were measured. The contents of carbohydrate. crude protein. crude fat and crude ash are 63.71%, 18.75%, 1.67% and 6.48%, respectively And the calories and total dietary fiber of P. asiatica was 466.71 Kcal. Total dietary fiber was 22.68%, respectively. The contents of essential and non-essential amino acids were 4.815.22 mg and 6.591.04 mg, respectively. The K was the largest mineral followed by P, Ca, Mg, and Na, which means P. asiatica is alkali material. The EDA of P. asiatica was 59.32~70.30%, and the activity was dependent on the sample concentration. Total phenolic content of P. asiatica was $79.65{\mu}g/g$, and total flavonoids content was $4.43{\mu}g/g$. The P. asiatica extract showed the highest reducing power (3.5) at a concentration of 25 mg/mL. Based on the above results, we deemed that the P. asiatica might have potential antioxidant activities. The general nutrients and other antioxidant bioactive materials in P. asiatica were also potential materials for good health food.

• Journal of Bio-Environment Control
• /
• v.16 no.1
• /
• pp.7-12
• /
• 2007

This study was conducted to clarify the effects of the different concentration of the nutrient solution on the early growth and the nutritional contents of hydroponically grown Aster koraiensis, Hemerocallis fulva and Plantago asiatica at 70 days after transplanting in perlite culture. Balanced nutrient solution formulated by Japanese Horticultural Experiment Station was used as the standard concentration of the nutrient solution. Overall plant growth of Aster koraiensis and Hemerocallis fulva such as plant height, stem diameter, number of loaves, fresh and dry shoot and root weight were significantly increased in 1.5 times concentration of nutrient solution. Shoot and root fresh and dry weight of hydroponically grown Plantago asiatica were significantly increased in the higher concentration of the nutrient solution, however, number of loaves and root length were significantly increased in the standard and the lower concentration of the nutrient solution. The highest contents of calcium, magnesium and sodium in plants were shown in Aster koraienxis which were grown in the 1.5 times concentration of nutrient solution, and Hemerocallis fulva and Plantago asiatica in 0.25 times of that. The contents of potassium in Aster koraiensis and Hemerocallis fulva were significantly increased when the plants were grown in the 0.5 times concentration of the nutrient solution, and that in Plantago asiatica in the 1.5 times concentration of the nutrient solution. The contents of phosphoric acid in plants as affected by the different species of Namul and the different concentration of the nutrient solution were not significant.

• Korean Journal of Organic Agriculture
• /
• v.32 no.1
• /
• pp.91-105
• /
• 2024

Plantago asiatica L. (P. asiatica) is a perennial plant belonging to the plantaginaceae and is useful in treating a various diseases such as wounds, bronchitis, and chronic constipation. The bioactive effects of P. asiatica extract was evaluated to determine its potential for use as a variety materials in the food, pharmaceutical, and agricultural industries. Polyphenol and flavonoid contents, free radical scavenging, reducing power activity, and reactive oxygen species (ROS) expression were measured to identify the antioxidative activity. Anti-inflammatory effects were evaluated via analysis of nitric oxide (NO) and pro-inflammatory protein expression in LPS-induced RAW 264.7 cell. As a result of measuring the antioxidant activities of the P. asiatica extract, the total polyphenol content was 50.91±0.78 mg gallic acid equivalents/g and the flavonoid content was 100.99±0.44 mg rutin equivalents/g, and both DPPH and ABTS radical scavenging activities and reducing power increased depending on the concentration. Also, intracellular ROS production was inhibited by the P. asiatica extract. No cytotoxicity was observed when P. asiatica extract was treated, and NO and inflammatory protein expression were inhibited, and nuclear factor kappa B (NF-κB) phosphorylation was also inhibited in a concentration-dependent manner. In conclusion, P. asiatica is a functional natural resources of antioxidant and anti-inflammatory agents that can be used in various industries, including food and agriculture.