• 동의생리병리학회지
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• 제32권2호
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• pp.134-140
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• 2018

This study aims to evaluate healthcare providers' satisfaction and demands pertaining to the collaborative first-stage pilot project between Korean medicine and Western medicine. This survey was conducted via electronic mail among 33 healthcare providers participating in the pilot project. Likert type 5-point scale or Likert type 7-point scale was used to evaluate each item. The response of '${\geq}4$' on the 5-point scale, and '${\geq}5$' on the 7-point scale were analyzed as positive answers. A total of 27 healthcare providers (81.8%) responded, of which 9 were western medical doctors (33.3%) and 18 were Korean medical doctors (66.7%). In respect to satisfaction of the pilot project, 88.9% gave positive responses on improved patients' convenience, 59.3% on treatment efficiency and 55.6% on diagnosis efficiency. In terms of self-evaluation on the pilot project, 70.4% gave positive answers on changes in quality of collaborative treatment, 74.1% on cooperation of results, 63.0% on cooperation of structure and 51.9% on cooperation of process. In terms of demand for collaborative treatment or the pilot project, 'standardized manual' and 'simplification of administrative procedures' showed highest demand, resulting up to 88.9%, followed by 85.2% demanding more public relations and 63.9% demanding enlargement of participating hospitals. This survey revealed that healthcare providers are generally satisfied with patients' convenience and treatment effects. Further studies are needed to develop a standardized manual, simplified administrative procedures, and expanded pilot project contents.

• 한국보육지원학회지
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• 제7권3호
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• pp.43-65
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• 2011

본 연구의 목적은 가정과 학원에서 이루어지는 영아의 조기영어교육 실태를 조사하고 영아어머니들의 영아영어교육에 대한 요구에의 영향 변인을 분석하는 것이었다. 연구대상은 어린이집에 다니는 36개월 미만의 자녀를 둔 어머니 441명이었다. 질문 조사에 의해 수집된 자료로써 빈도분석과 로지스틱 회귀분석을 하였다. 연구결과, 조사대상의 30.9%가 영어교육을 하고 있으며, 주로 어린이집에서의 영어교육을 계기로, 시작시기는 생후 24개월~36개월 이전에 교육을 시작한 것으로 나타났다. 교육실태는 공통적으로 주 1~2회, 회당 30분 미만 실시, 5만원 미만의 월교육비, 교사는 영어를 전공한 한국인, '간단한 회화'를 위해 시청각 자료의 사용, 학습지나 워크북의 높은 활용으로 요약되었다. 한편, 66.0%의 어머니가 영아영어교육에 대해 긍정적 입장을 취하며, 자녀 연령과 월수입이 높을수록, 그리고 신경생리학적, 언어학적, 사회적 영어교육 요구 근거에 동의할수록 교육 요구가 긍정적일 확률이 높았다. 본 연구결과를 통해 영아영어교육에 대한 바람직한 안내가 보다 구체적으로, 시급하게 이루어질 필요가 있다고 시사되었다.

• 원예과학기술지
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• 제33권6호
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• pp.845-853
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• 2015

The objective of this study was to predict the timing of nitrogen (N) demand through analyzing chlorophyll fluorescence (ChlF), soil-plant analysis development (SPAD), and normalized difference vegetation index (NDVI), which are positively correlated with foliar N concentration in star cluster (Pentas lanceolata). The plants were grown in potting soil under optimal conditions for 30 d, followed by weekly irrigation with five concentrations (0, 4, 8, 16, and 24 mM) of N for an additional 30 d. These five N application levels corresponded to leaf N concentrations of 2.62, 3.48, 4.00, 4.23, and 4.69%, respectively. We measured 13 morphological and physiological parameters, as well as the responses of these parameters to various N-fertilizer treatments. The general increases in Dickson's quality index (DQI), above-ground dry weight (DW), total DW, flowering rate, ${\Delta}F/Fm$', and qP in response to treatment with 0 to 8 mM N were similar to those of SPAD, NDVI, and Fv/Fm. Consistent and strong correlations ($R^2$= 0.60 to 0.85) were observed between leaf N concentration (%) and SPAD, NDVI, ${\Delta}F/Fm$', and above-ground DW. Validation of leaf S PAD, NDVI, and ${\Delta}F/Fm$' revealed that these vegetation indices are accurate predictors of leaf N concentration that can be used for non-destructive estimation of the proper timing for N-solution irrigation of P. lanceolata. Moreover, irrigation with 8 mM N-fertilizer i s recommended w hen leaf N concentration, SPAD, NVDI, and ${\Delta}F/Fm$' ratios are reduced from their saturation values of 4.00, 50.68, 0.64, and 0.137%, respectively.

• 생물환경조절학회지
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• 제2권1호
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• pp.27-36
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• 1993

Carbon dioxide enrichment for greenhouse crops has generally been a standard commercial practice for many years. Vegetable crops such as tomato, cucumber, and lettuce respond positively to the $CO_2$ enrichment. But improper $CO_2$ enrichment leads to physiological damage and economical loss. This study was carried out to develop a $CO_2$ concentration control algorithm considering growth stage and efficiency. The measurand was $CO_2$ consumption rate and top fresh weight that represents growth stage. The weight of top fresh lettuce as a whole in the tray was measured through a non-destructive method. The demand in $CO_2$ concentration according to growth stage was investigated. The results are summarized as follows. 1. The $CO_2$ consumption rate could be measured within the error of $\pm$ 15.4mg$CO_2$/hr in the range of $CO_2$ concentration of 500-1500ppm. 2. The weight of top fresh lettuce could be measured within the error $\pm$ 4.3g in the range of 0-1400g. 3. The $CO_2$ control model developed could determine an economical $CO_2$ supply rate considering $CO_2$ consumption rate and leakage rate. 4. The $CO_2$ control algorithm based on the control model was composed of feedforward control for maintaining a stable $CO_2$ concentration level, and feedback control with $CO_2$ consumption rate and top fresh weight for adapting to the change in $CO_2$ demand by growth stage. 5. For the performance test with the developed control algorithm on lettuce the decrease in $CO_2$ supply rate was obtained without a significant decrease in top fresh weight.

• 생명과학회지
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• 제26권6호
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• pp.727-736
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• 2016

쌀은 인류가 가장 많이 먹고 있는 주식이다. 최근 백색미, 적색미, 갈색미, 녹색미 그리고 흑색미 등 다양한 품종들이 소비되고 있다. 고농도의 안토시아닌이 함유되어 있는 흑미는 영양가뿐만 아니라 암 발생 예방 효과가 있어 세계적으로 그 소비가 증가되고 있다. 유전학적으로 흑미는 cyanidin-3-O-glucoside (C3G)의 합성경로를 조절하는 두 개의 유전자 Pb와 Pp가 관여하는 Purple Pericarp (Prp) 유전형질에 의하여 종자과피의 색이 결정된다. 1921년 Nagai가 흑미의 유전현상을 일으키는 Prp 형질을 보고한 이 후 Prp 형질에 관여하는 유전자들과 그 기능 분석에 관한 많은 연구가 보고 되었으나 아직도 많은 부분이 밝혀지지 않았다. 그러나 안토시아닌의 함량이 높은 기능성 흑미의 소비는 증가하고 있는 반면 흑미는 일반 재배 벼에 비하여 상대적인 수확량이 매우 적어 농경제적인 문제가 있다. 본 논문에서는 흑미 종자가 성숙하는 과정에서 Prp 유전자의 유전현상의 특성과 안토시아닌 합성 경로 그리고 수확량에 관한 유전학적 관점에서 내용을 정리하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제27권1호
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• pp.147-154
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• 2014

This review focuses on modulation of growth hormone (GH) and its downstream actions on periparturient dairy cows undergoing physiological and metabolic adaptations. During the periparturient period, cows experience a negative energy balance implicating that the feed intake does not meet the total energy demand for the onset of lactation. To regulate this metabolic condition, key hormones of somatotropic axis such as GH, IGF-I and insulin must coordinate adaptations required for the preservation of metabolic homeostasis. The hepatic GHR1A transcript and GHR protein are reduced at parturition, but recovers on postpartum. However, plasma IGF-I concentration remains low even though hepatic abundance of the GHR and IGF-I mRNA return to pre-calving value. This might be caused by alternation in IGFBPs and ALS genes, which consequently affect the plasma IGF-I stability. Plasma insulin level declines in a parallel manner with the decrease in plasma IGF-I after parturition. Increased GH stimulates the lipolytic effects and hepatic glucose synthesis to meet the energy requirement for mammary lactose synthesis, suggesting that GH antagonizes insulin-dependent glucose uptake and attenuates insulin action to decrease gluconeogenesis.

• 센서학회지
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• 제29권2호
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• pp.100-104
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• 2020

Thus far, several in vivo biosensing platforms have been proposed to measure the mechanical contractility of cultured cardiomyocytes. However, the low sensitivity and screening rate of the developed sensors severely limit their practical applications. In addition, intensive research and development in cardiovascular disease demand a high-throughput drug-screening platform based on biomimetic engineering. To overcome the drawbacks of the current state-of-the-art methods, we propose a high-throughput drug-screening platform based on 16 functional high-sensitivity well plates. The proposed system simulates the physiological accuracy of the heart function in an in vitro environment. We fabricated 64 cantilevers using highly flexible and optically transparent silicone rubber and placed in 16 independent wells. Nanogrooves were imprinted on the surface of the cantilever to promote cell alignment and maturation. The adverse effects of the cardiovascular drugs on the cultured cardiomyocytes were systematically investigated. The 64 cantilevers demonstrated a highly reliable and reproducible mechanical contractility of the drug-treated cardiomyocytes. Real-time high-throughput screening and simultaneous evaluation of the cardiomyocyte mechanical contractility under multiple drugs verified that the proposed system could be used as an efficient drugtoxicity test platform.

• Journal of Animal Science and Technology
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• 제58권5호
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• pp.18.1-18.10
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• 2016

Muscle, studied mostly with respect to meat production, represents one of the largest protein reservoirs of the body. As gene expression profiling holds credibility to deal with the increasing demand of food from animal sources, excessive loss due to myopathies and other muscular dystrophies was found detrimental as it aggravates diseases that result in increased morbidity and mortality. Holding key point towards improving the developmental program of muscle in meat producing animals, elucidating the underlying mechanisms of the associated pathways in livestock animals is believed to open up new avenues towards enhancing the lean tissue deposition. To this end, identification of vital candidate genes having no known function in myogenesis, is believed to increase the current understanding of the physiological processes going on in the skeletal muscle tissue. Taking consequences of gene expression changes into account, knowledge of the pathways associated with their activation and as such up-regulation seems critical for the overall muscle homeostasis. Having important implications on livestock production, a thorough understanding of postnatal muscle development seems a timely step to fulfil the growing need of ever increasing populations of the world.

• 대한인간공학회지
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• 제32권1호
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• pp.37-45
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• 2013

Objective: This study describes the change of operator performance in drastic change of illumination level, and proposes an alternative method to cope with it. Background: The control standard of illumination for nuclear power plants(NPPs) is based on the set of limit criteria for maintaining a specific illumination level. However, there is a possibility to cause human errors according to the psychological and physiological influences to operators in the situation of drastic change of illumination such as SBO(Station Black Out), so a basic study is necessary to review the current approach. Method: We assessed the visual fatigue, subjective work load and task performance according to the three illumination situations(Normal Illumination, Emergency Illumination, and Drastic Change of Illumination). Result: Research finding shows that there are not significant differences in task performance between normal illumination (1,000lx level) and emergency illumination (100lx level), only if beyond the dark adaptation limit. However, subjective work load on mental demand and visual fatigue show a potential challenge to visual performance in drastic change of illumination. Conclusion/Application: Several trials can complement this challenge in NPPs by applying 3-way communication, enhancing readability of procedures, and managing the visual factors affecting the operators' performance through a Visual Environment Management Program including visual health aspects, etc.

• 동의생리병리학회지
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• 제26권3호
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• pp.386-391
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• 2012

The purposes of this study were to investigate the difference on activities of daily living(ADL), instrumental activities daily of living(IADL) and quality of life of aged woman with dementia reported by aged woman with dementia and caregivers. From December 2009 to February 2010, 64 subjects in the institutionalized aged woman with dementia, 22 caregivers were surveyed through structured questionnaires. There was no difference ADL and quality of life of aged woman with dementia reported by aged woman with dementia and caregivers. But, there was significant differences in IADL. Also, ADL was positively related to IADL in aged woman with dementia and caregivers. ADL and IADL were negatively related to quality of life in aged woman with dementia and caregivers. In daily activity and life quality, there is no difference recognized by aged woman with dementia and caregivers. So it's not matter for the nursery to recognize the demand of the aged woman with dementia and to care them. It is necessary to study the elderly with dementia at home, and to compare the patients in accordance with severity.