• Imaging Science in Dentistry
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• 제51권2호
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• pp.107-115
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• 2021

Purpose: This study aimed to demonstrate the presence of dental caries through a photoacoustic imaging system with visible and near-infrared wavelengths, highlighting the differences between the 2 spectral regions. The depth at which carious tissue could be detected was also verified. Materials and Methods: Fifteen permanent molars were selected and classified as being sound or having incipient or advanced caries by visual inspection, radiography, and optical coherence tomography analysis prior to photoacoustic scanning. A photoacoustic imaging system operating with a nanosecond pulsed laser as the light excitation source at either 532 nm or 1064 nm and an acoustic transducer at 5 MHz was developed, characterized, and used. En-face and lateral(depth) photoacoustic signals were detected. Results: The results confirmed the potential of the photoacoustic method to detect caries. At both wavelengths, photoacoustic imaging effectively detected incipient and advanced caries. The reconstructed photoacoustic images confirmed that a higher intensity of the photoacoustic signal could be observed in regions with lesions, while sound surfaces showed much less photoacoustic signal. Photoacoustic signals at depths up to 4 mm at both 532 nm and 1064 nm were measured. Conclusion: The results presented here are promising and corroborate that photoacoustic imaging can be applied as a diagnostic tool in caries research. New studies should focus on developing a clinical model of photoacoustic imaging applications in dentistry, including soft tissues. The use of inexpensive light-emitting diodes together with a miniaturized detector will make photoacoustic imaging systems more flexible, user-friendly, and technologically viable.

• Neurospine
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• 제15권4호
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• pp.306-322
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• 2018

This review introduces the current technique of photoacoustic imaging as it is applied in imaging-guided surgery (IGS), which provides the surgeon with image visualization and analysis capabilities during surgery. Numerous imaging techniques have been developed to help surgeons perform complex operations more safely and quickly. Although surgeons typically use these kinds of images to visualize targets hidden by bone and other tissues, it is nonetheless more difficult to perform surgery with static reference images (e.g., computed tomography scans and magnetic resonance images) of internal structures. Photoacoustic imaging could enable real-time visualization of regions of interest during surgery. Several researchers have shown that photoacoustic imaging has potential for the noninvasive diagnosis of various types of tissues, including bone. Previous studies of the surgical application of photoacoustic imaging have focused on cancer surgery, but photoacoustic imaging has also recently attracted interest for spinal surgery, because it could be useful for avoiding pedicle breaches and for choosing an appropriate starting point before drilling or pedicle probe insertion. This review describes the current instruments and clinical applications of photoacoustic imaging. Its primary objective is to provide a comprehensive overview of photoacoustic IGS in spinal surgery.

• 한국광학회지
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• 제28권4호
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• pp.158-165
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• 2017

광 흡수체로부터 측정되는 광음향 신호의 크기가 광 흡수계수 값의 증가에 따라 증가하다가 포화되는 광음향 비선형성에 대한 기존의 분석에서는 초음파 측정기의 물리적 형태를 고려하지 않았다. 이 논문에서는 초음파 측정기의 구면 초점 형태가 광음향 비선형성에 미치는 영향을 분석하였다. 구면 초점 초음파 측정기의 공간 필터링에 의한 광음향 공명 현상을 고려하고 기존의 광음향 비선형성에 대한 연구 방법을 보완하여 구면 초점 초음파 측정기로 측정한 광음향 신호에 대한 해석식을 이론적으로 유도하였다. 이 해석식에 의한 결과는 광음향 신호가 특정한 광 흡수계수 값에서 최대값을 나타내고 최대값 이후로는 광 흡수계수 값의 증가에 따라 오히려 감소함을 보였다. 주파수 영역에서 구면 초점 초음파 측정기에 의해 측정된 광음향 신호의 공명 스펙트럼과 초음파 측정기의 주파수 전달 함수를 비교하여 이 기존의 통념과는 다른 특징을 보이는 광음향 비선형성을 이해하였다. 또한, 이 주파수 영역에서의 물리적 해석으로 인해 광음향을 발생시키는 광 흡수체 내부의 광 조도 형태도 광음향 비선형성에 영향을 미친다는 것을 알 수 있었다.

• 한국자동차공학회논문집
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• 제11권2호
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• pp.111-118
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• 2003

Recently, environmental damage to urban area becomes serious problem due to the exhaust emissions by increasing the number of vehicle. Especially, exhaust emission from diesel vehicles are blown to be harmful to human health and environment. Photoacoustic Spectroscopy system is very useful technology for simultaneous and continuous measurement of the various components of the automotive exhaust gas. In this study, in order to reduce emission gases from automobile, we tried to develop the measurement system of Photoacoustic Spectroscopy. To improve performance of high sensitive Photoacoustic Spectroscopy system for automotive exhaust emissions, the shape of Photoacoustic Spectroscopy cell was optimized to use the flow analysis. And Exhaust emission data of the 1,500cc gasoline engine was fixed the working fluid. The characteristics of fluid flow for cell were analyzed by various conditions in detail.

• The Journal of Korean Physical Therapy
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• 제22권4호
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• pp.83-89
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• 2010

Purpose: The goal of this study was to investigate the feasibility for the early diagnosis of inflammatory arthritis by the reconstruction of three-dimensional photoacoustic imaging with a tissue phantom. Methods: Q-switched Nd:YAG laser (l = 532 nm) was applied to a tissue phantom to generate photoacoustic waves, and the acquired photoacoustic signals at different positions around the sample were used to recombine the distribution of the optical absorption and the images were subsequently generated through a reconstruction algorithm. Results: From the acquired photoacoustic signals, the surface andinner core of the phantom was clearly distinguished. Furthermore, the back-projection algorithm was able to reconstruct two-dimensional and three-dimensional photoacoustic images that contained the optical absorption property information of the tissue phantom. Conclusion: The results indicate that the photoacoustic imaging technique has many advantages such as high optical contrast and high acoustic resolution. The acquired images can be used for the early diagnosis of inflammatory arthritis by the structural information obtained from the region of interest.

• Journal of the Optical Society of Korea
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• 제18권2호
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• pp.151-155
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• 2014

Although various ophthalmic imaging methods, including fundus photography and optical coherence tomography, have been applied for effective diagnosis of ocular diseases with high spatial resolution, most of them are limited by shallow imaging penetration depth and a narrow field of view. Also, many of those imaging modalities are optimized to provide microscopic anatomical information, while functional or cellular information is lacking. Compared to other ocular imaging modalities, photoacoustic imaging can achieve relatively deep penetration depth and provide more detailed functional and cellular data based on photoacoustic signal generation from endogenous contrast agents such as hemoglobin and melanin. In this paper, array-based ultrasound and photoacoustic imaging was demonstrated to visualize pigmentation in the eye as well as overall ocular structure. Fresh porcine eyes were visualized using a real-time ultrasound micro-imaging system and an imaging probe supporting laser pulse delivery. In addition, limited photoacoustic imaging field of view was improved by an imaging probe tilting method, enabling visualization of most regions of the retina covered in the ultrasound imaging.

• 한국광학회지
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• 제30권2호
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• pp.48-58
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• 2019

구면 초점 초음파 측정기에 의해 구형의 광 흡수체로부터 측정된 시간(즉, 펄스 형태 광원) 및 주파수 영역(즉, 처프 형태 광원) 광음향 신호의 신호 대 잡음비(signal-to-noise ratio)를 이론 및 시뮬레이션으로 분석하였다. 이전 문헌과 마찬가지로 시간 영역 광음향 측정에 의한 신호 대 잡음비 값이 주파수 영역 광음향 측정의 경우보다 더 높았는데 이 근본적인 이유를 최대허용노광량(maximum permissible exposure)에 따른 광원의 세기와 주파수 필터링을 통한 두 측정 모드의 광음향 스펙트럼들에 대한 분석을 통해 이해하였다. 또한, 분석의 결과로서 주파수 영역 광음향의 처프 형태 광원에 대한 정합 필터링에 더해 DC 스펙트럼 부분을 제거하니 신호 대 잡음비가 5 dB 정도 상승하는 것을 발견하였다. 특히, 주파수 필터 함수의 주파수 상한 값의 변화에 따라 신호대 잡음비 값이 급격하게 변동하였는데 신호 대 잡음비가 최대가 되는 주파수 상한 값이 두 광음향 측정 모드에서 서로 다르게 나타남을 관찰하였다.

• 한국음향학회:학술대회논문집
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• 한국음향학회 1984년도 추계학술발표회 논문집
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• pp.33-35
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• 1984

A new type single beam photoacoustic spectrometer suitable for measuring optical absorption of condensed powder matter with the automatic calibration capability of a source power spectrum is introduced. The signal processing until of this spectrometer consists of a photoacoustic cell a lock-in amp., a switching circuit and a personal computer. The measured optical absorption spectra of a few material by this method are good agreement with the results obtained by the double-beam photoacoustic spectrometer.

• 대한화학회지
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• 제61권4호
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• pp.139-142
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• 2017

Ethene ($C_2H_4$), which is produced in plants as they mature, was used to study its photoacoustic properties using photoacoustic spectroscopy. Detection of trace amounts, with $N_2$ gas, of $C_2H_4$ gas was also applied. The gas was tested in various conditions-temperature, concentration of the gas, gas cell length, and power of the laser- to determine their effect on the photoacoustic signal, the ideal conditions to detect trace gas amounts, and concentration of $C_2H_4$ produced by an avocado and a banana. A detection limit of 10 ppm was determined for pure $C_2H_4$. A detection of 5% and 13% (by volume) concentration of $C_2H_4$ was produced for a ripening avocado and banana, respectively, in closed space.

• 한국음향학회지
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• 제13권6호
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• pp.24-30
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• 1994

본 논문에서는 금속에서의 광음향신호를 분석하기 위해 CW $CO_{2}$ 레이저를 사용하여 광음향 신호검출 시스템을 구성하였으며 알루미늄, 탄소강 및 활동을 샘플로 선택하고 레이저 변조주파수, 록인앰프의 시정수를 변화시키면서 샘플의 종류 및 두께에 따른 수 nA정도의 광음향 신호를 검출하여 신호처리 기법에 의해 금속에서의 광음향 신호의 특성을 분석하였다. 실험결과 시정수를 조정하여 광음향 신호를 안정화시킬 수 있었고 광음향 신호는 금속고유의 열팽창계수에 대한 열용량에 비례하여 증가하고 샘플두께 및 변조주파수에 대하여 지수함수적으로 감소함을 확인하였다.