A Preliminary Study on Developing a Photoacoustic Imaging System for Inflammatory Arthritis Diagnosis

관절염 진단용 광음향 이미징 시스템 개발을 위한 선행 연구

  • Youn, Jong-In (Department of Biomedical Engineering, College of Medical Science, Catholic University of Daegu) ;
  • Park, Ji-Won (Department of Physical Therapy, College of Medical Science, Catholic University of Daegu)
  • 윤종인 (대구가톨릭대학교 의료과학대학 의공학과) ;
  • 박지원 (대구가톨릭대학교 의료과학대학 물리치료학과)
  • Received : 2010.06.23
  • Accepted : 2010.08.08
  • Published : 2010.08.25

Abstract

Purpose: The goal of this study was to investigate the feasibility for the early diagnosis of inflammatory arthritis by the reconstruction of three-dimensional photoacoustic imaging with a tissue phantom. Methods: Q-switched Nd:YAG laser (l = 532 nm) was applied to a tissue phantom to generate photoacoustic waves, and the acquired photoacoustic signals at different positions around the sample were used to recombine the distribution of the optical absorption and the images were subsequently generated through a reconstruction algorithm. Results: From the acquired photoacoustic signals, the surface andinner core of the phantom was clearly distinguished. Furthermore, the back-projection algorithm was able to reconstruct two-dimensional and three-dimensional photoacoustic images that contained the optical absorption property information of the tissue phantom. Conclusion: The results indicate that the photoacoustic imaging technique has many advantages such as high optical contrast and high acoustic resolution. The acquired images can be used for the early diagnosis of inflammatory arthritis by the structural information obtained from the region of interest.

Keywords

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