• Title/Summary/Keyword: phase-contrast

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Holographic Recording Versus Holographic Lithography

  • Seungwoo Lee
    • Current Optics and Photonics
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    • v.7 no.6
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    • pp.638-654
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    • 2023
  • Holography is generally known as a technology that records and reconstructs 3D images by simultaneously capturing the intensity and phase information of light. Two or more interfering beams and illumination of this interference pattern onto a photosensitive recording medium allow us to control both the intensity and phase of light. Holography has found widespread applications not only in 3D imaging but also in manufacturing. In fact, it has been commonly used in semiconductor manufacturing, where interference light patterns are applied to photolithography, effectively reducing the half-pitch and period of line patterns, and enhancing the resolution of lithography. Moreover, holography can be used for the manufacturing of 3D regular structures (3D photonic crystals), not just surface patterns such as 1D or 2D gratings, and this can be broadly divided into (i) holographic recording and (ii) holographic lithography. In this review, we conceptually contrast two seemingly similar but fundamentally different manufacturing methods: holographic recording and holographic lithography. We comprehensively describe the differences in the manufacturing processes and the resulting structural features, as well as elucidate the distinctions in the diffractive optical properties that can be derived from them. Lastly, we aim to summarize the unique perspectives through which each method can appear distinct, with the intention of sharing information about this field with both experts and non-experts alike.

Corrosion Behavior of Bimetal Materials (Fe-Ni / Fe-Ni-Mo) for Electromagnetic Switches (전자 개폐기용 바이메탈 소재(Fe-Ni / Fe-Ni-Mo)의 부식거동)

  • Yu-Jeong An;Eun-Hye Hwang;Jae-Yeol Jeon;Sung Jin Kim
    • Corrosion Science and Technology
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    • v.22 no.6
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    • pp.478-483
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    • 2023
  • This study examined the corrosion behavior of bimetal materials composed of Fe-Ni alloy and Fe-Ni-Mo alloy, both suitable for use in electromagnetic switches. Electrochemical polarization and weight loss measurements revealed that, in contrast to Fe-Ni alloy, which exhibited pseudo-passivity behavior, Fe-Ni-Mo alloy had higher anodic current density, displaying only active dissolution and greater weight loss. This indicated a lower corrosion resistance in the Fe-Ni-Mo alloy. Equilibrium calculations for the phase fraction of precipitates suggested that the addition of 1 wt% Mo may lead to the formation of second-phase precipitates, such as Laves and M6C, in the γ matrix. These precipitates might degrade the homogeneity of the passive film formed on the surface, leading to localized attacks during the corrosion process. Therefore, considering the differences in corrosion kinetics between these bimetal materials, the early degradation caused by galvanic corrosion should be prevented by designing a new alloy, optimizing heat treatment, or implementing periodic in-service maintenance.

Diagnostic Value of Computed Tomography in Crohn's Disease Patients Presenting with Acute Severe Lower Gastrointestinal Bleeding

  • Lee, Sunyoung;Ye, Byong Duk;Park, Seong Ho;Lee, Kyung Jin;Kim, Ah Young;Lee, Jong Seok;Kim, Hyun Jin;Yang, Suk-Kyun
    • Korean Journal of Radiology
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    • v.19 no.6
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    • pp.1089-1098
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    • 2018
  • Objective: To investigate the diagnostic yield of contrast-enhanced computed tomography (CT) in Crohn's disease (CD) patients presenting with acute severe lower gastrointestinal bleeding (LGIB), and the role of CT in predicting the risk of rebleeding. Materials and Methods: A consecutive series of 110 CD patients presenting with acute severe LGIB between 2005 and 2016 were analyzed. Among them, 86 patients who had undergone contrast-enhanced CT constituted the study cohort. The diagnostic yield of CT for detecting contrast extravasation was obtained for the entire cohort and compared between different CT techniques. In a subgroup of 62 patients who had undergone CT enterography (CTE) and showed a negative result for extravasation on CTE, the association between various clinical and CTE parameters and the risk of rebleeding during subsequent follow-up was investigated using Cox regression analysis. Results: The diagnostic yield of CT was 10.5% (9 of 86 patients). The yield did not significantly differ between single-phase and multiphase examinations (p > 0.999), or between non-enterographic CT and CTE (p = 0.388). Extensive CD (adjusted hazard ratio [HR], 3.27; 95% confidence interval [CI], 1.09-9.80; p = 0.034) and bowel wall-to-artery enhancement ratio (adjusted HR, 2.81; 95% CI, 1.21-6.54; p = 0.016) were significantly independently associated with increased rebleeding risks, whereas anti-tumor necrosis factor-${\alpha}$ therapy after the bleeding independently decreased the risk of rebleeding (adjusted HR, 0.26; 95% CI, 0.07-0.95; p = 0.041). Conclusion: The diagnostic yield of contrast-enhanced CT was not high in CD patients presenting with acute severe LGIB. Nevertheless, even a negative CTE may be beneficial as it can help predict the risk of later rebleeding.

Comparative effects of corn-based diet and phase-fed cassava-based diet on growth rate, carcass characteristics and lipid profile of meat-type ducks

  • Saree, Saowalak;Bunchasak, Chaiyapoom;Rakangtong, Choawit;Sakdee, Jessada;Krutthai, Nuttawut;Poeikhampha, Theerawit
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.6
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    • pp.843-848
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    • 2017
  • Objective: This experiment was conducted to evaluate the effects of a corn- or cassava- based diet on the production of meat-type ducks. Methods: Four hundred day-old ducks were used in this experiment. They were divided into five groups with each group replicated eight times. The ducks fed the corn-based diets served as the control group. The four other groups comprised different treatments, with each one given the cassava-based diet based on phase-feeding. Three treatments were fed the cassava-based diet from 16, 28, and 35 d; respectively up to 42 d of age and the other group was fed the cassava-based diet from 1 to 42 d of age. Results: The results indicated that ducks on either the corn- or cassava-based diets were similar in growth during 1 to 9 d of age. However, toward 35 to 42 d, the cassava-diet produced a higher weight gain (p<0.05). The cassava-based diet was better than the corn-based diet at increasing the outer and inner breast weights at 28, 35, or 42 d (p<0.05). In contrast, the corn-based diet was better at increasing abdominal fat (p<0.05). The two diets did not differ in their effects on the serum triglyceride, cholesterol, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, very-low-density lipoprotein-cholesterol, and liver cholesterol. The corn-based diet, however, caused a highly significantly greater level of liver triglyceride (p<0.01). Conclusion: The results of this study suggest that both the cassava- and corn- based diets are similar in their effect on meat-type ducks during the starter stage but toward the finisher stage, the cassava-based diet has a better influence on weight gain and carcass characteristics.

Changes in Nerve Excitability During Neural Stretching (신경 신장 적용 시간에 따른 신경흥분성 변화)

  • Lee, Dong-Rour;Rhee, Min-Hyung;Eom, Ju-Ri;Kim, Jong-Soon
    • PNF and Movement
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    • v.16 no.2
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    • pp.287-294
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    • 2018
  • Purpose: The neurodynamic test used to implicate symptoms arising from the nerve is proposed to selectively increase the strain of the nerve without increasing the strain of adjacent tissue, although this has not yet been established in the time of nerve tension application. This study aimed to investigate the acute effects of nerve stretching time on nerve excitability using compound nerve action potential (CNAP) analysis. Methods: Thirty healthy young adults (mean age=23.10 years) with no medical history of neurological or musculoskeletal disorder voluntarily participated in this study. Nerve excitability was assessed using the median nerve conduction velocity test. The amplitude of the CNAP was measured under three conditions: resting phase (supra-maximal stimulus, without nerve stretching), baseline phase (two-thirds of the supra-maximal stimulus, without nerve stretching), and stretch phase (two-thirds of the supra-maximal stimulus, with 1-5 minutes nerve stretching). One-way repeated measures ANOVA was conducted to compare the latency and amplitude of CNAP. A post-hoc test was analyzed using the contrast test. Results: The latency was significantly delayed after 1 min. of nerve stretching in comparison with the baseline test. However, no significant difference was found during the nerve stretching (1-5 min.). The amplitude was significantly increased by nerve stretching. Conclusion: Nerve stretching can induce nerve excitability without any nerve injury. Based on the results, more than 1 min. of nerve stretching as a neurodynamic test can be a useful method in the clinical setting.

Microstructures and Mechanical Properties of SiC Containing $SiC_{platelet}$ Seeds of Various Size (여러 가지 크기의 $SiC_{platelet}$ Seed를 함유한 SiC 세라믹스의 미세구조 및 기계적 특성)

  • Choi, Myoung-Je;Park, Chan;Park, Dong-Soo;Kim, Hai-Doo
    • Journal of the Korean Ceramic Society
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    • v.36 no.10
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    • pp.1094-1101
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    • 1999
  • Liquid phase sintered silicon carbides were obtained by sintering of $\alpha$-SiC and $\beta$-SiC powders as starting materials at 2173K and 2273K respectively. The SiCplatelet seeds of different sizes were obtained by a repeated ball milling and sedimentation. Their mean size (d50) were 2.217 ${\mu}{\textrm}{m}$ 13.67 ${\mu}{\textrm}{m}$, 22.17${\mu}{\textrm}{m}$ respectively 6wt%Al2O3-4 wt% Y2O3 was used as the sintering additives for the liquid phase sintering. The two silicon carbides had a bimodal microstructure consisting of small matrix grains and large platelike grains when the SiCplatelet seeds were added. In the case of the $\beta$-SiC the appreciable phase transformation occurred as sintering temperature increased from 2173K to 2273K and resulted in matrix shape change from equiaxed into platelike grains. In contrast there was no shape change for the $\alpha$-SiC. The size of large grains in the $\alpha$-SiC of large grains in the $\alpha$-SiC was larger than that of the large grains in the $\beta$-SiC These results suggested that the growth of the $\alpha$-SiCplatelet in the $\alpha$-SiC matrix was more favored than that of the $\alpha$-SiCplatelet in the $\beta$-SiC matix. The three point flexural strength decreased as the added seed size increased. Fracture toughness values of samples sintered at 2273K were higher than those of samples sintered at 2173K.

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Effects of Fertilization on Physiological Parameters in American Sycamore (Platanus occidentalis) during Ozone Stress and Recovery Phase

  • Han, Sim-Hee;Kim, Du-Hyun;Lee, Jae-Cheon;Kim, Pan-Gi
    • Journal of Ecology and Environment
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    • v.32 no.3
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    • pp.149-158
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    • 2009
  • American sycamore seedlings were grown in chambers with two different ozone concentrations ($O_3$-free air and air with additional $O_3$) for 45 days. Both the control and the $O_3$ chambers included non-fertilized and fertilized plants. After 18 days of $O_3$ fumigation, seedlings were placed in a clean chamber for 27 days. Seedlings under ozone fumigation showed a significant decrease in pigment contents and photosynthetic activity, and a significant increase in lipid peroxidation. Fertilization enhanced physiological damage such as the inhibition of photosynthetic activity and the increase of lipid peroxidation under ozone fumigation. During the recovery phase, the physiological damage level of seedlings increased with ozone fumigation. In addition, physiological damage was observed in the fertilized seedlings. Superoxide dismutase (SOD) and glutathione reductase (GR) activities of $O_3$-treated seedlings increased up to 33.8% and 16.3% in the fertilized plants. The increase of SOD activity was higher in the fertilized plants than in the non-fertilized plants. Negative effects of ozone treatment were observed in the biomass of the leaves and the total dry weight of the fertilized sycamore seedlings. The $O_3$-treated seedlings decreased in stem, root and total dry weight, and the loss of biomass was statistically significant in the fertilized plants. In conclusion, physiological disturbance under normal nutrient conditions has an effect on growth response. In contrast, in conditions of energy shortage, although stress represents a physiological inhibition, it does not seem to affect the growth response.

GTP Induces S-phase Cell-cycle Arrest and Inhibits DNA Synthesis in K562 Cells But Not in Normal Human Peripheral Lymphocytes

  • Moosavi, Mohammad Amin;Yazdanparast, Razieh;Lotfi, Abbas
    • BMB Reports
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    • v.39 no.5
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    • pp.492-501
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    • 2006
  • Since differentiation therapy is one of the promising strategies for treatment of leukemia, universal efforts have been focused on finding new differentiating agents. In that respect, we used guanosine 5'-triphosphate (GTP) to study its effects on K562 cell line. GTP, at concentrations between 25-200 ${\mu}M$, inhibited proliferation (3-90%) and induced 5-78% increase in benzidine-positive cells after 6-days of treatments of K562 cells. Flow cytometric analyses of glycophorine A (GPA) showed that GTP can induce expression of this marker in more mature erythroid cells in a time- and dose-dependent manner. These effects of GTP were also accompanied with inhibition of DNA synthesis (measured by [$^3H$]-thymidine incorporation) and early S-phase cell cycle arrest by 96 h of exposure. In contrast, no detectable effects were observed when GTP administered to unstimulated human peripheral blood lymphocytes (PBL). However, GTP induced an increase in proliferation, DNA synthesis and viability of mitogen-stimulated PBL cells. In addition, growth inhibition and differentiating effects of GTP were also induced by its corresponding nucleotides GDP, GMP and guanosine (Guo). In heat-inactivated medium, where rapid degradation of GTP via extracellular nucleotidases is slow, the anti-proliferative and differentiating effects of all type of guanine nucleotides (except Guo) were significantly decreased. Moreover, adenosine, as an inhibitor of Guo transporter system, markedly reduced the GTP effects in K562 cells, suggesting that the extracellulr degradation of GTP or its final conversion to Guo may account for the mechanism of GTP effects. This view is further supported by the fact that GTP and Guo are both capable of impeding the effects of mycophenolic acid. In conclusion, our data will hopefully have important impact on pharmaceutical evaluation of guanine nucleotides for leukemia treatments.

Impact of Cumulus Parameterization Schemes on the Regional Climate Simulation for the Domain of CORDEX-East Asia Phase 2 Using WRF Model (WRF 모형의 적운 모수화 방안이 CORDEX 동아시아 2단계 지역의 기후 모의에 미치는 영향)

  • Choi, Yeon-Woo;Ahn, Joong-Bae
    • Atmosphere
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    • v.27 no.1
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    • pp.105-118
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    • 2017
  • This study assesses the performance of the Weather Research and Forecasting (WRF) model in reproducing regional climate over CORDEX-East Asia Phase 2 domain with different cumulus parameterization schemes [Kain-Fritch (KF), Betts-Miller-Janjic (BM), and Grell-Devenyi-Ensemble (GD)]. The model is integrated for 27 months from January 1979 to March 1981 and the initial and boundary conditions are derived from European Centre for Medium-Range Weather Forecast Interim Reanalysis (ERA-Interim). The WRF model reasonably reproduces the temperature and precipitation characteristics over East Asia, but the regional scale responses are very sensitive to cumulus parameterization schemes. In terms of mean bias, WRF model with BM scheme shows the best performance in terms of summer/winter mean precipitation as well as summer mean temperature throughout the North East Asia. In contrast, the seasonal mean precipitation is generally overestimated (underestimated) by KF (GD) scheme. In addition, the seasonal variation of the temperature and precipitation is well simulated by WRF model, but with an overestimation in summer precipitation derived from KF experiment and with an underestimation in wet season precipitation from BM and GD schemes. Also, the frequency distribution of daily precipitation derived from KF and BM experiments (GD experiment) is well reproduced, except for the overestimation (underestimation) in the intensity range above (less) then $2.5mm\;d^{-1}$. In the case of the amount of daily precipitation, all experiments tend to underestimate (overestimate) the amount of daily precipitation in the low-intensity range < $4mm\;d^{-1}$ (high-intensity range > $12mm\;d^{-1}$). This type of error is largest in the KF experiment.

Alternative Evaluation Method of GFI-based Construction Value Engineering (GFI를 활용한 건설공사 시공VE 대안평가 방법)

  • Kim, Sooyong;Lee, Youngrok;Yang, Jinkook
    • Korean Journal of Construction Engineering and Management
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    • v.16 no.3
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    • pp.3-10
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    • 2015
  • Value engineering (VE) of the construction project is classified into design phase value engineering and construction phase value engineering. Design phase value engineering must apply to over 10 billion public construction projects by government law. Therefore, the design value engineering apply to actively in construction projects. In contrast, the construction value engineering apply to a limited certain construction project. The reason is that construction value engineering process can not reflect practical demands quality. The construction value engineering can implement to positive impact through the feasibility verification for constructability. In this research, we propose a method of construction value engineering that reflect the practical demands. This method is experts alternative evaluation of using by GFI-based. And, this study was applied to the practical cases to verify the applicability of the proposed method. As a result, proposed alternative evaluation method were analyzed highly efficient in terms of applying the process as well as the method compare to the conventional method.