• 제목/요약/키워드: personalized nutrition

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과체중과 비만 여성의 HbA1c 지표에 따른 당뇨병 예방을 위한 영양상담의 효과 (Benefits of Nutrition Consultation for Preventing Diabetes According to HbA1c Levels in Overweight and Obese Women)

  • 권용진;선우섭;문황운;박유경
    • 대한영양사협회학술지
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    • 제19권2호
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    • pp.112-123
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    • 2013
  • HbA1c was recently adopted as a reliable indicator for screening diabetes. This study investigated the ability of nutrition consultation to prevent diabetes in overweight women (BMI 23 $kg/m^2$ or more) using HbA1c as an indicator. Twenty overweight and obese women (with $HbA1c{\geq}5.7$%) completed the 12-week nutritional study, with individual and personalized nutrition counseling performed every 2 weeks. The main study guidelines involved the following: 1) reducing the intake of high fat foods and alcohol, 2) consuming a large amount of vegetables, 3) reducing the intake of simple sugars and empty-calorie foods, and 4) increasing physical activity to ${\geq}30$ min/day. Anthropometric (height, weight, BMI, body muscle (kg), body fat (%), waist and hip circumference, blood pressure) and biochemical parameters (fasting blood sugar (FBS), HbA1c, lipid profiles, hs-CRP) were measured before and after the nutrition consultation. After 12 weeks, the HbA1c<5.7% group had significant decreases in BMI, WC, HC, WHR, HbA1c, hs-CRP and also dietary intake of energy (P<0.01), carbohydrates, lipids (P<0.01), proteins (P<0.01) and cholesterol was significantly decreased (P<0.05). In the HbA1c ${\geq}5.7$% group, HbA1c, TC, LDL, NON-HDL, hs-CRP and dietary intake of energy, carbohydrate, lipid, protein, and cholesterol significantly decreased (P<0.05). These results suggest that nutrition consultation effectively helps to prevent diabetes in overweight and obese women after applying HbA1c standards. Overall, the improvement in all markers measured suggest that HbA1c is a good indicator for blood glucose regulation, helping to prevent diabetes.

소금민감성유전자와 비만 (Salt-sensitive genes and their relation to obesity)

  • 전용필;이명숙
    • Journal of Nutrition and Health
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    • 제50권3호
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    • pp.217-224
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    • 2017
  • Purpose: Although it is well known thatmortality and morbidity due to cardiovascular diseases are higher in salt-sensitive subjects than in salt-resistant subjects, their underlying mechanisms related to obesity remain unclear. Here, we focused on salt-sensitive gene variants unrelated to monogenic obesity that interacted with sodium intake in humans. Methods: This review was written based on the modified $3^rd$ step of Khans' systematic review. Instead of the literature, subject genes were based on candidate genes screened from our preliminary Genome-Wide Association Study (GWAS). Finally, literature related to five genes strongly associated with salt sensitivity were analyzed to elucidate the mechanism of obesity. Results: Salt sensitivity is a measure of how blood pressure responds to salt intake, and people are either salt-sensitive or salt-resistant. Otherwise, dietary sodium restriction may not be beneficial for everyone since salt sensitivity may be associated with inherited susceptibility. According to our previous GWAS studies, 10 candidate genes and 11 single nucleotide polymorphisms (SNPs) associated with salt sensitivity were suggested, including angiotensin converting enzyme (ACE), ${\alpha}$-adducin1 (ADD1), angiotensinogen (AGT), cytochrome P450 family 11-subfamily ${\beta}$-2 ($CYP11{\beta}$-2), epithelial sodium channel (ENaC), G-protein b3 subunit (GNB3), G protein-coupled receptor kinases type 4 (GRK4 A142V, GRK4 A486V), $11{\beta}$-hydroxysteroid dehydrogenase type-2 (HSD $11{\beta}$-2), neural precursor cell-expressed developmentally down regulated 4 like (NEDD4L),and solute carrier family 12(sodium/chloride transporters)-member 3 (SLC 12A3). We found that polymorphisms of salt-sensitive genes such as ACE, $CYP11{\beta}$-2, GRK4, SLC12A3, and GNB3 may be positively associated with human obesity. Conclusion: Despite gender, ethnic, and age differences in genetics studies, hypertensive obese children and adults who are carriers of specific salt-sensitive genes are recommended to reduce their sodium intake. We believe that our findings can contribute to the prevention of early-onset of chronic diseases in obese children by facilitating personalized diet-management of obesity from childhood to adulthood.

위장질환 예방을 위한 다중회귀분석을 이용한 식이지식 예측 (Prediction of Dietary Knowledge using Multiple Regression Analysis for Preventing Stomach Diseases)

  • 최소영;김주창;정경용
    • 한국융합학회논문지
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    • 제10권7호
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    • pp.1-6
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    • 2019
  • 현대사회는 1인가구가 증가함에 따라 불규칙한 식습관으로 인해 영양이 불균형하게 포진되어있다. 이러한 식습관은 위장질환, 소화기 질환 등 만성질환의 발병률을 증가시켰다. 본 논문은 위장질환 예방을 위한 다중회귀분석을 이용한 식이지식 예측을 제안한다. 제안하는 방법은 식이지식 예측을 통해 사용자의 위장질환과 식이영양을 관리하는 방법이다. 헬스 플랫폼에서 스마트 기기를 통해 수집된 사용자의 PHR을 통합한다. 통합된 데이터로부터 다중회귀분석을 이용하여 사용자의 식이와 활동량 변화를 분석한다. 사용자의 식이 성분과 소모 칼로리, 기초대사와 같은 상황정보를 입력으로 적절한 식이성분, 위장질환 수치의 변화를 예측하고 필요할 것으로 나타나는 영양성분을 사용자에게 권장한다. 이를 통해 현대인들은 균형 잡힌 식사를 통해 위장질환을 관리할 수 있다.

식품 3D-프린팅 기술과 식품 산업적 활용 (Food 3D-printing Technology and Its Application in the Food Industry)

  • 김종태;맹진수;신원선;심인철;오승일;조영희;김종훈;김철진
    • 산업식품공학
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    • 제21권1호
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    • pp.12-21
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    • 2017
  • Foods are becoming more customized and consumers demand food that provides great taste and appearance and that improves health. Food three-dimensional (3D)-printing technology has a great potential to manufacture food products with customized shape, texture, color, flavor, and even nutrition. Food materials for 3D-printing do not rely on the concentration of the manufacturing processes of a product in a single step, but it is associated with the design of food with textures and potentially enhanced nutritional value. The potential uses of food 3D-printing can be forecasted through the three following levels of industry: consumer-produced foods, small-scale food production, and industrial scale food production. Consumer-produced foods would be made in the kitchen, a traditional setting using a nontraditional tool. Small-scale food production would include shops, restaurants, bakeries, and other institutions which produce food for tens to thousands of individuals. Industrial scale production would be for the mass consumer market of hundreds of thousands of consumers. For this reason, food 3D-printing could make an impact on food for personalized nutrition, on-demand food fabrication, food processing technologies, and process design in food industry in the future. This article review on food materials for 3D-printing, rheology control of food, 3D-printing system for food fabrication, 3D-printing based on molecular cuisine, 3D-printing mobile platform for customized food, and future trends in the food market.

노인 당뇨병 인지자의 연령에 따른 삶의 질 수준 분석: 국민건강영양조사를 이용하여 (Health-related quality of life in elderly patients with diabetes mellitus according to age: based on Korea National Health and Nutrition Examination Survey)

  • 강예지;박경
    • Journal of Nutrition and Health
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    • 제53권2호
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    • pp.129-140
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    • 2020
  • 본 연구는 국민건강영양조사 2008-2016년 자료를 이용하였고, 그중 자신이 당뇨병을 앓고 있다는 것을 인지하고 있는 65세 이상 노인들을 대상으로 분석을 실시하였다. 총 2,353명을 대상으로 세부 연령 그룹별 정신건강 특성, 식이 섭취수준 및 HRQoL 수준을 비교하였다. 노인 당뇨병 인지자들을 65-69세, 70-74세, ≥ 75세로 분류하여 EQ-5D 개별 항목과 index 수준을 비교 분석한 결과 5가지 항목 중, 연령이 높을수록 운동능력, 자기관리, 일상활동, 통증/불편 항목의 수준이 낮은 결과를 보였고, EQ-5D index 또한 가장 낮은 것으로 나타났다. 노인 당뇨병 환자의 경우, 질환을 통해 직접적인 영향을 받는 것과 노화로 인해 나타나는 여러 기능장애들이 함께 동반되는 경우가 많기 때문에 이를 반영한 개별적인 치료 및 관리가 필요한 실정이다. 이에 따라 노인 당뇨병 환자들의 건강관리에서 HRQoL 측정의 중요성은 강조되며, 지속적인 추적 조사를 통해 노인 당뇨병 환자들의 건강에 영향을 주는 특정 요인에 대한 체계적인 관리 및 파악이 가능할 것으로 생각된다. 또한 이를 고려하여 국내 당뇨병 환자의 HRQoL 수준을 향상시키는 것은 개인의 건강관리뿐만 아니라 국가의 보건복지정책에 이바지할 수 있을 것으로 사료된다.

식생활 라이프스타일 유형이 다이어트 도시락 선택속성의 중요도에 미치는 영향 (Effects of Food-related Lifestyle on the Importance of Selected Attributes of Diet Lunch Box)

  • 김빛나;심기현
    • 한국식품영양학회지
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    • 제30권3호
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    • pp.413-426
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    • 2017
  • The study subjects were 302 adult males and females aged more than 20 years living in the metropolitan area of South Korea. This study was conducted to obtain baseline data to establish proper development and marketing strategies by examining the effects of food-related lifestyles on the importance of diet, purchasing behavior towards diet lunch boxes, and their selected attributes such as menu, packaging, and services. With respect to food-related lifestyle, a cluster analysis was performed by using five factors such as convenience factor, health factor, safety factor, taste factor, and economy factor obtained from factor analysis to derive the economy type, the taste and economy type, the convenience type, the safety type, and the health type. As a result, the respondents regarded 'food hygiene (4.59)', 'freshness (4.47)', 'taste (4.28)', and 'nutrient balance (4.19)' as the selected attributes of diet lunch box menus. Moreover, the importance of diet lunch box menus (${\beta}=0.179$) was increased with increasing safety orientation. 'Shelf life label (4.42)' was the most important selected attribute of diet lunch boxes, followed by 'ingredient label (4.19)', 'nutrition facts label (4.16)', and 'indication of origin (4.15)'. In particular, the importance of packaging for diet lunch boxes (${\beta}=0.203$) was increased with increasing safety orientation. With respect to the selected attributes of services in purchasing diet lunch boxes, 'provision of personalized menus (4.07)' was the most important, and the importance of services for diet lunch box (${\beta}=0.160$) was increased with increasing taste and economy orientation. Based on the above results, the respondents gave importance to the selected attributes related to food safety and health such as hygiene and, freshness. In addition, they also placed emphasis on hygiene and safe factors such as shelf life, ingredients, and nutrition facts labels. Therefore, it is considered necessary to develop diet lunch boxes by taking these factors into account. Furthermore, in services for diet lunch boxes, it is considered necessary to establish a service system capable of providing consumers with specialized menu or nutrition counseling according to the food-related lifestyle for their proper health management. Particularly, because consumers place emphasis on both food hygiene and safety, and health, it is considered necessary to thoroughly manage hygiene, safety, and nutrition in menu or packaging so that it is possible to enhance customer satisfaction by considering these selected attributes in greater detail.

부산지역 일부병원 치료식 섭취 환자의 영양상담에 대한 인식 및 만족도 (Perception and Satisfaction on Nutrition Counseling Service for Patients Consuming a Therapeutic Diet at Hospitals in Busan)

  • 이정례;손은주;류은순
    • 한국식품영양과학회지
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    • 제39권9호
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    • pp.1305-1312
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    • 2010
  • 본 연구는 병원 영양과에서 실시하고 있는 치료식 섭취환자의 영양상담에 대한 인식과 영양상담 만족도 요인으로서의 지식전달 요인, 인지적 대화요인, 감성적 대화요인, 촉진능력 요인과의 관계를 파악함으로써 앞으로 병원 영양과에서 환자들의 영양상담에 대한 만족도를 높이는데 필요한 기초자료를 제공하고자 시도하였다. 조사대상은 부산지역 400 병상 이상의 병원에 입원중인 치료식 섭취환자를 퇴원하기 직전에 직접 1:1 면담법을 이용하여 설문조사를 실시하였다. 배부된 설문지 중 총 153부(98.7%)를 분석에 사용하였으며 본 조사는 2008년 1월 21일~2월 28일에 진행하였다. 조사대상 환자 중 영양상담을 받은 경험이 있는 환자가 전체의 57.5%로 나타났고, 영양상담을 받은 계기는 의료진이 권해서가 64.1%로 가장 높았고 영양상담 방법은 개별교육이 58.0%로 나타났다. 영양상담에 대한 인식에서 영양상담 이해에 대한 긍정적인 견해는 75.0%, 중요도는 83.0%, 영양관리에 도움이 되는 정도는 78.7%로 나타났다. 영양상담에 대한 전체 만족도 점수는 3.80점이며, 각 세부요인에서 지식전달 요인 3.80점, 인지적 대화 요인 3.71점, 감성적 대화 요인 4.05점, 촉진능력 요인은 3.61점으로 나타났다. 영양상담의 만족도 점수가 낮은 항목은 '퇴원 후 식사요법 정보제공', '맞춤형 영양정보 제공', '구체적인 식단 제시', '식단 작성 방법 설명'으로 나타났다. 영양상담에 대한 인식인 이해도, 중요도 및 영양관리 도움정도는 영양상담에 대한 만족도인 지식전달 요인, 인지적 대화 요인, 감성적 대화 요인, 촉진 능력 요인과 모두 유의적인(p<0.01) 양의 상관관계를 나타냈다. 이상의 결과를 살펴볼 때, 영양사들은 환자들의 영양에 대한 이해도 및 중요도를 높일 수 있는 다양한 영양상담 도구의 개발 및 활용 방안에 대한 노력이 필요하겠다. 환자와의 영양상담시 환자 스스로 영양관리를 독립적으로 실행에 옮길 수 있도록 환자들을 위한 구체적인 식단제시, 조리방법, 맞춤형 영양관리 방법 등의 촉진 요인들에 대해서 영양사들은 더 많은 관심을 가져야 하겠다. 즉, 실제 식사와 관련된 조리체험교실, 시식회 등의 개최를 통해 환자들에게 보다 직접적이고 실질적으로 다가갈 수 있는 환자 중심적인 영양상담이 필요하며 특히, 맞춤형 영양상담을 통해 환자의 치료 효과를 높이기 위해서는 현재로서는 부족한 영양사 인력의 증원이 절실히 필요하겠다.

Biochemical Nutritional Status of Serum Lipids, Protein, and Blood Glucose in School Children in Bucheon

  • Koo Jae Ok;Kim Soon Ki;Shin Dong Mi
    • Journal of Community Nutrition
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    • 제7권1호
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    • pp.3-7
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    • 2005
  • This study was conducted to evaluate nutritional status of school children by biochemical assessment method. Subjects were 308 school children from 4th to 6th grade living in Bucheon city. Their blood glucose, total protein, albumin, total cholesterol, and triglyceride (TG) concentrations were determined. Mean blood glucose concentration was 77.56 mg/dl and $81.2\%$ of children had normal blood glucose concentration. The average proportion of hypoglycemia was $18.8\%$ among the three grades and prevalence of hypoglycemia in 4th grade school children was highest ($21.8\%$). Mean serum total protein and albumin levels were 7.14g/dl and 4.35g/dl, respectively, and all the subjects except only one were in normal range of total protein and albumin. Mean serum TG and total cholesterol concentrations were 145.82mg/dl and 94.50mg/dl. Serum TG and total cholesterol levels showed same pattern that the concentrations decreased in proportion to grade. Especially, there was significant difference between grades in serum total cholesterol. Furthermore, $11.7\%$ of 4th, $6.8\%$ of 5th, and $2.8\%$ of 6th grade school children have borderline hypertriglycemia or hypertriglycemia, risk factors of obesity or cardiovascular disease later in life. Taken together, there was conflict phenomenon that undernutrition of hypertriglycemia and overnutrition of hypertriglycemia existed together. Therefore, it is needed to develop discriminating and personalized nutritional feeding, counseling, and education program to cover the children of under- or over- nutritional status.

학생건강체력평가제(PAPS)를 기반으로 한 비만아동관리 프로토콜 (Obesity management Protocol based physical activity promotion system(PAPS) for obese children)

  • 강선영
    • 융합보안논문지
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    • 제15권5호
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    • pp.47-52
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    • 2015
  • 본 연구에서는 학생건강체력평가제(PAPS)기반 데이터를 활용하여 비만아동을 관리하기 위한 효과적인 프로토콜을 제시하였다. 매년 시행되는 PAPS는 비만평가를 포함하고 있는데, 학교에서는 PAPS에서 얻은 데이터를 통해 급증하고 있는 비만아동의 관리를 위한 노력을 하고 있다. 그러나 현실적으로 학교 교사들의 업무 부담과 제공인력 부족으로 인해 비만아동들의 사후관리에는 효율적이지 못했다. 보다 체계적이고 적극적인 관리를 위해서는 web-PAPS 접속을 통해 학생이나 학부모가 건강종합평가나 비만의 유무를 확인하고 신체활동 처방을 확인할 수 있었던 기존의 방식에 스마트 디바이스 전송방식을 결합하여 정보에의 접근을 용이하게 하는 것이 효율적이다. web-PAPS에서 비만아동의 부모에게 자녀의 체력 및 건강, 비만에 관련한 정보를 자동으로 전송하여, 개인의 상태에 적절하게 처방된 운동과 영양에 대한 처방내용 및 교육내용을 부모와 공유하게 될 때 비만관리에 더욱 효과적일 것이다.

Dexamethasone-induced muscle atrophy and bone loss in six genetically diverse collaborative cross founder strains demonstrates phenotypic variability by Rg3 treatment

  • Bao Ngoc Nguyen;Soyeon Hong;Sowoon Choi;Choong-Gu Lee;GyHye Yoo;Myungsuk Kim
    • Journal of Ginseng Research
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    • 제48권3호
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    • pp.310-322
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    • 2024
  • Background: Osteosarcopenia is a common condition characterized by the loss of both bone and muscle mass, which can lead to an increased risk of fractures and disability in older adults. The study aimed to elucidate the response of various mouse strains to treatment with Rg3, one of the leading ginsenosides, on musculoskeletal traits and immune function, and their correlation. Methods: Six Collaborative Cross (CC) founder strains induced muscle atrophy and bone loss with dexamethasone (15 mg/kg) treatment for 1 month, and half of the mice for each strain were orally administered Rg3 (20 mg/kg). Different responses were observed depending on genetic background and Rg3 treatment. Results: Rg3 significantly increased grip strength, running performance, and expression of muscle and bone health-related genes in a two-way analysis of variance considering the genetic backgrounds and Rg3 treatment. Significant improvements in grip strength, running performance, bone area, and muscle mass, and the increased gene expression were observed in specific strains of PWK/PhJ. For traits related to muscle, bone, and immune functions, significant correlations between traits were confirmed following Rg3 administration compared with control mice. The phenotyping analysis was compiled into a public web resource called Rg3-OsteoSarco. Conclusion: This highlights the complex interplay between genetic determinants, pathogenesis of muscle atrophy and bone loss, and phytochemical bioactivity and the need to move away from single inbred mouse models to improve their translatability to genetically diverse humans. Rg3-OsteoSarco highlights the use of CC founder strains as a valuable tool in the field of personalized nutrition.