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The Effect of (-)-Hydroxycitrate on Weight Control Program in Obese Women -I : Effect on Anthropometric Parameters- ((-)-Hydroxycitrate를 이용한 비만 여성의 체중 조절 프로그램 실시 및 효과 평가에 관한 연구(I))

  • 문수재
    • Journal of Nutrition and Health
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    • v.30 no.2
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    • pp.155-169
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    • 1997
  • This study investigated the effect of weight control by using the commercial appetite suppressant ((-)-hydroxycitric acid(HCA) formula) and nutrition education on 72 obese women over a period of 8 weeks. During the study it conducted nutritional education for women to control their weight, thus analyzed their changes in anthropometric variables. All obese women were randomized in a double-blind method to consume either HCA(HCA group : experimental group) or placebo(placebo group : control group). Two groups were also divided randomly into 2 groups combined with commercial formula diet in 1 meal a day(HD group and PD group : HCA + gormula diet and placebo + formula diet) or not(HO group and conducted with 4 groups(HD, HO, PD, and PO group). All subjects were assigned to consume 800-1500kcal/d balanced diet which is 500kcal less than their usual energy requirement. To evaluate the effect of the weight control program, weight, percent of body fat, waist and hip circumferences, and 5 skinfold thickness were measured up to 5 times in all obese women. The mean weight of the subjects at the onset of the study was 76.5$\pm$10.6kg. The mean body mass index(BMI) wa 30.1$\pm$3.8 and it was in the upper 5 percentile of mean BMI of Korean women. At the end of the program, mean weight loss was 3.5kg after 2 weeks(p<0.001), and 5.8kg after 4 weeks(p<0.001). The waist, hip ratio(WHR) and skinfold thickness measurements of biceps, triceps, subscapular, suprailiac and abdominum showed significant reduction over the entire study period(p<0.05). These outcome were evaluated by effect of nutritional education and counselling. The reduction of % of body fat was significantly different among the 4 groups. Women who administrated HCA demonstrated more change in weight, BMI than the placebo group. There was also significant reduction in body composition (% of body fat, WHR, and skinfold thickness) than the other groups. The HD group which was administrated HCA combined with formula diet was more decreased than other groups. It showed that this program using commercial HCA and formula diet induced not only a change in weight but also a change in body composition. The outcome of this study suggests that HCA has a more effctive change on weight control which is carried out with nutritional education and counselling.

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The Relationship of Depressive Symptomatology with a Glycemic Control in Korean Women (한국 여성에서 우울증상과 혈당 조절의 연관성)

  • Yoon, Dae-Hyun;Park, Jin-Ho;Park, Min-Jeong;Shin, Chan-Soo;Cho, Sang-Heon;Oh, Byung-Hee
    • Korean Journal of Psychosomatic Medicine
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    • v.14 no.1
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    • pp.47-52
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    • 2006
  • Backgrounds : Depression has been prevalent in women and maintaining optimal glycemic control is an important goal of diabetes management. Although depression is common in adults with diabetes, its relationship to glycemic control remains unclear, espacilly in Korean women. The current study examined the relationship of depressive symptomatology with glycemic control in Korean women. Methods : Beck depression inventory (BDI), $HbA_{1c}$ as an index of long-term glycemic control, fasting glucose level and body mass index (BMI) were measured in sample of 4,567 women of whom 4.7%, 216 women had diabetes, and the relationship between depression and glycemic control was analyzed. BDI Scores of 16 and above is a cut off point to indicate possible clinical depression. Results The frequency of depressed women (p<0.001) and the mean score of BDI (p<0.001) were significantly higher in diabetic women. The mean level of $HbA_{1c}$ (p<0.01) and fasting glucose (p<0.05) were higher in depressed women. There was a graded relationship between the percentile of depressed women and a degree of glycemic control impairment (p=0.001). Conclusion : The current study found the relationship of depressive symptomatology with glycemic control in Korean women. This relationship may be mediated by decreased self-care behaviors or by neurobiological dysregulation. Improving identification and treatment of depression in women with diabetes might have favorable effects on diabetic outcomes.

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Trace-level Determination of N-nitrosodimethylamine(NDMA) in Water Samples using a High-Performance Liquid Chromatography with Fluorescence Derivatization (HPLC와 Fluorescence Derivatization 기법을 이용한 극미량 NDMA의 수질분석)

  • Cha, Woo-Suk;Fox, Peter;Nalinakumari, Brijesh;Choi, Hee-Chul
    • Journal of Korean Society of Environmental Engineers
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    • v.28 no.2
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    • pp.223-228
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    • 2006
  • High-performance liquid chromatography(HPLC) and fluorescence derivatization were applied for a trace-level N-nitrosodimethylamine(NDMA) analysis of water samples. Fluorescence intensity was optimized with the excitation wavelength of 340 nm and the emission wavelength of 530 nm. pH adjustment after denitrosation was necessary to get a maximum intensity at pH between 9 and 12. Maximum intensity was found with a dansyl chloride concentration of 330 to 500 mg/L. Percentile error in the water sample analyses through solid phase extraction was 12-162% and 6-23% for the lower concentration level(10-200 ng/L NDMA) and the higher level(100-1000 ng/L NDMA), respectively, showing more discrepancy in lower level. However, the average ratios of estimated NDMA to the standard NDMA were close to 1 for both concentration ranges, presenting this HPLC method could detect from tens to hundreds nanograms NDMA per liter. Accurate determination of NDMA, which was injected to a wastewater effluent, revealed the selectivity of fluorescence derivatization for the target compound(NDMA) in the presence of complex interfering compounds. The HPLC with fluorescence derivatization may be applicable for determining NDMA of water and wastewater samples fur various research purposes.

Effect of nutritional supplement formula on catch-up growth in young children with nonorganic faltering growth: a prospective multicenter study

  • Shim, Jung Ok;Kim, Seung;Choe, Byung-Ho;Seo, Ji-Hyun;Yang, Hye Ran
    • Nutrition Research and Practice
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    • v.14 no.3
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    • pp.230-241
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    • 2020
  • BACKGROUND/OBJECTIVES: Inadequate nutrition in infants and young children affects physical growth and neurocognitive development. Therefore, early nutritional intervention is important to promote catch-up growth in young children with faltering growth. The aim of this study was to evaluate the effect of nutritional supplementation with a pediatric concentrated and balanced nutritional supplement formula on promoting growth and improving nutritional status in children with nonorganic faltering growth. SUBJECTS/METHODS: Children aged 12-36 months whose body weight-for-age was < 5th percentile on the Korean Growth Charts were enrolled. Children born premature or having organic diseases were excluded. Children were instructed to consume 400 mL of formula per day in addition to their regular diet for 6 months. Pediatricians and dietitians educated the parents and examined the subjects every 2 months. Anthropometric parameters were measured at baseline and at 2, 4, and 6 months, and laboratory tests were done at baseline and 6 months. The good consumption group included children who consumed ≥ 60% of the recommended dose of formula. RESULTS: Total 82 children completed the 6-month intervention. At baseline, there were no significant differences in all variables between the good consumption and poor consumption groups. Weight and weight z-scores were significantly improved in the good consumption group compared to the poor consumption group at the end of the intervention (P = 0.009, respectively). The good consumption group showed a significant trend for gaining weight (P < 0.05) and weight z-score (P < 0.05) compared to the poor consumption group during 6 months of formula intake. The concentration of blood urea nitrogen was significantly increased in the good consumption group (P = 0.001). CONCLUSIONS: Nutritional supplementation with a concentrated and balanced pediatric nutritional formula along with dietary education might be an effective approach to promote catch-up growth in children with nonorganic faltering growth.

Estimation of the Probability of Exceeding PM2.5 Standards in Busan (부산지역에서의 PM2.5 기준치 미달성확률 추정)

  • Chang, Jae-Soo;Cheong, Jang Pyo
    • Journal of Korean Society for Atmospheric Environment
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    • v.28 no.6
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    • pp.697-705
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    • 2012
  • Particulate matter (PM) data collected from the Urban Air Monitoring Network in Busan during the period from 2006 through 2010 were statistically examined and analyzed to estimate the probability of exceeding $PM_{2.5}$ 24 hour and annual standard to be implemented from January $1^{st}$, 2015. For Jangrimdong, Yeonsandong, Kijangeup, and Jwadong where simultaneous measurement of $PM_{10}$ and $PM_{2.5}$ was conducted, the probability of exceeding $PM_{2.5}$ standards was estimated using $PM_{2.5}$ data measured on site. For other areas where there were no measured $PM_{2.5}$ data available, the probability of exceeding $PM_{2.5}$ standards was statistically estimated using $PM_{10}$ measured on site and $PM_{2.5}/PM_{10}$ ratios obtained from the four stations where both $PM_{2.5}$ and $PM_{10}$ were monitored simultaneously. At Jangrimdong, Yeonsandong, Kijangeup, and Jwadong, mean value of annual 99 percentile of 24 hr average $PM_{2.5}$ for 5 years from 2006 through 2010 was 99.3, 74.5. 57.0, and $62.5{\mu}g/m^3$, respectively, and the probability of exceeding $PM_{2.5}$ 24 hr standard was estimated at 100%. For areas where there were no measured $PM_{2.5}$ data available, the estimated probability of exceeding $PM_{2.5}$ 24 hr standard was more than 0.82. Mean value of annual average $PM_{2.5}$ from 2008 through 2010 was 31.7 and $27.6{\mu}g/m^3$ for Jangrimdong and Yeonsandong, respectively, which exceeded $PM_{2.5}$ annual standard of $25{\mu}g/m^3$. Mean value of annual average $PM_{2.5}$ during the same period for Kijangeup and Jwadong was 19.2 and $20.7{\mu}g/m^3$, respectively, which satisfied $PM_{2.5}$ annual standard. For other areas where there were no measured $PM_{2.5}$ data available, the probability of exceeding $PM_{2.5}$ annual standard was more than 0.95 except Taejongdae and Kwangahndong. With $PM_{10}$ and $PM_{2.5}$ data measured at 17 Urban Air Monitoring Stations in Busan, the probability of exceeding $PM_{2.5}$ standards was estimated to be very high for almost all areas. This result indicates that proper measures to mitigate $PM_{2.5}$ in Busan should be investigated and established as soon as possible.

Family history of chronic renal failure is associated with malnutrition in Korean hemodialysis patients

  • Hwang, Ji-Yun;Cho, Ju-Hyun;Lee, Yoon-Jung;Jang, Sang-Pil;Kim, Wha-Young
    • Nutrition Research and Practice
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    • v.3 no.3
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    • pp.247-252
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    • 2009
  • The present study was to investigate the nutritional status and factors related to malnutrition in end-stage renal disease (ESRD) patients requiring hemodialysis (HD) in South Korea. Subjects were ESRD outpatients from general hospitals or HD centers in Seoul referred to the dialysis clinic for maintenance HD care. A total of 110 patients (46 men and 64 women; mean ages $58.6{\pm}1.0y$) were eligible for this study. The family history of chronic renal failure (CRF) was considered positive if a patient reported having either a first-degree or second-degree relative with CRF. Malnutrition was defined as a triceps skinfold thickness or mid-ann muscle circumference below the fifth percentile for age and sex and forty-seven of the 110 patients were malnourished. Almost all (94%) patients had anemia (hemoglobin: <13 g/dL for men and <12 g/dL for women). Energy intake was below the recommended intake levels of energy [30-35 kcal/kg ideal body weight (IBW)] and protein (1.2 g/kg IBW) in 60% of patients. The duration of HD was longer in malnourished HD patients (P=0.0095). Malnutrition was more prevalent in women (P=0.0014), those who never smoked (P=0.0007), nondiabetic patients (P=0.0113), and patients with bone diseases (P=0.0427), adequate HD (spKt/$V{\geq}1.2$) (P=0.0178), and those with a family history of CRF (P=0.0255). Multiple logistic regression was used to examine the relationship between malnutrition and potential risk factors. After adjusting for age, sex, and other putative risk factors for malnutrition, the OR for malnutrition was greater in HD patients with a family history of CRF (OR, 3.290; 95% CI, $1.003{sim}10.793$). Active nutrition monitoring is needed to improve the nutritional status of HD patients. A family history of CRF may be an independent risk factor for malnutrition in Korean HD patients. A follow-up study is needed to investigate whether there is a causal relationship between a family history of CRF and malnutrition in Korean ESRD patients.

Application of Effective Regularization to Gradient-based Seismic Full Waveform Inversion using Selective Smoothing Coefficients (선택적 평활화 계수를 이용한 그래디언트기반 탄성파 완전파형역산의 효과적인 정규화 기법 적용)

  • Park, Yunhui;Pyun, Sukjoon
    • Geophysics and Geophysical Exploration
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    • v.16 no.4
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    • pp.211-216
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    • 2013
  • In general, smoothing filters regularize functions by reducing differences between adjacent values. The smoothing filters, therefore, can regularize inverse solutions and produce more accurate subsurface structure when we apply it to full waveform inversion. If we apply a smoothing filter with a constant coefficient to subsurface image or velocity model, it will make layer interfaces and fault structures vague because it does not consider any information of geologic structures and variations of velocity. In this study, we develop a selective smoothing regularization technique, which adapts smoothing coefficients according to inversion iteration, to solve the weakness of smoothing regularization with a constant coefficient. First, we determine appropriate frequencies and analyze the corresponding wavenumber coverage. Then, we define effective maximum wavenumber as 99 percentile of wavenumber spectrum in order to choose smoothing coefficients which can effectively limit the wavenumber coverage. By adapting the chosen smoothing coefficients according to the iteration, we can implement multi-scale full waveform inversion while inverting multi-frequency components simultaneously. Through the successful inversion example on a salt model with high-contrast velocity structures, we can note that our method effectively regularizes the inverse solution. We also verify that our scheme is applicable to field data through the numerical example to the synthetic data containing random noise.

Application of Rainfall Runoff Model with Rainfall Uncertainty (강우자료의 불확실성을 고려한 강우 유출 모형의 적용)

  • Lee, Hyo-Sang;Jeon, Min-Woo;Balin, Daniela;Rode, Michael
    • Journal of Korea Water Resources Association
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    • v.42 no.10
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    • pp.773-783
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    • 2009
  • The effects of rainfall input uncertainty on predictions of stream flow are studied based extended GLUE (Generalized Likelihood Uncertainty Estimation) approach. The uncertainty in the rainfall data is implemented by systematic/non-systematic rainfall measurement analysis in Weida catchment, Germany. PDM (Probability Distribution Model) rainfall runoff model is selected for hydrological representation of the catchment. Using general correction procedure and DUE(Data Uncertainty Engine), feasible rainfall time series are generated. These series are applied to PDM in MC(Monte Carlo) and GLUE method; Posterior distributions of the model parameters are examined and behavioural model parameters are selected for simplified GLUE prediction of stream flow. All predictions are combined to develop ensemble prediction and 90 percentile of ensemble prediction, which are used to show the effects of uncertainty sources of input data and model parameters. The results show acceptable performances in all flow regime, except underestimation of the peak flows. These results are not definite proof of the effects of rainfall uncertainty on parameter estimation; however, extended GLUE approach in this study is a potential method which can include major uncertainty in the rainfall-runoff modelling.

A Study of the Nursing Needs of Hospitalized medical Patients by Means of Nursing History Form (간호력(Nursing History)을 통해 본 내과 입원환자의 간호요구)

  • 전경애
    • Journal of Korean Academy of Nursing
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    • v.7 no.2
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    • pp.1-10
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    • 1977
  • Personalized Patient centered nursing care is increasingly difficult to achieve despite the fact that it remains one of our consistent goals. So, we must find away to individualized nursing care. One means, to achieve this is by use of the nursing history form, which has been developed to help the nurse make maximum use of her limited time with the patient, by obtaining systematically the information needed to plan his nursing care. The nursing history form can be used to collect data about individual nursing needs but also it lends itself to the collection of epidemiological data relevant to the needs of patient population. So this study was undertaken in an attempt to describe the general characteristics of the population studied, to find out their perceptions and expectations related to their illness and hospitalization, to find out specific basic needs and to examine the relationship between the patients nursing needs and demographic characteristics through the responses to the nursing history questions. The study population defined and selected was all the patients (70) who were admitted to Yonsei University Hospital from October 1 - 15, 1975. The direct interview method was used and the data were categorized by the investigator, according to the nature of responses to each question and were subjected to the percentile and the chi- square tests. The findings can be summarized as follows 11. General characteristics of the study population ; The population was made up mainly of urban patients who were highly educated. The age was equally distributed. 2. Patients, perceptions and expectations related to illness and hospitalization ; 88.6% of the patients knew about the reason for hospitalization but 64. 5% could state symptoms only. 37.5% recognized the cause of illness. Approximately three fourth of the patients expressed on expectation for early recovery. 60.0% of the patient responses indicated, that they expected less than 10 days of hospitalization. Of the total responses regarding hospitalization, 45.7% were negative about the post -hospitalization expectation, 45.7% expected to return to work. As a result of these findings, we can see that there is a great educational need, a psychological need and environmental need for adaptation to the hospital and a socio- economic need for the post - hospitalization period. 3. Specific basic needs : The physical needs include the problem of getting sufficient sleep (50.0%), difficulty in food intake(47.1%), problems with hospital diet (47.0%), abnormal condition of the skin(44.3%), problems with bowel elimination(35.7%), assistance with bathing(35.7%), pain(30.0%), difficulty in walking(30.0%) , difficulty in seeing(30.0%) problems in urinary elimination(20.0%) , and difficulty in hearing(10.0%), 4. Nursing needs and epidemiological characteristics ; Age distribution was related to the rendition of the mouth but no significant differences were observed statistically with the patients responses to the other nursing history questions according to the epidemiological variables of age, sex, education and residence.

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The Relationships between Preschool Teachers' Beliefs about the Purpose of Multicultural Education and Their Attitudes and Teaching Efficacy with Respect to Multicultural Education (유아교육기관 교사의 다문화교육 목표에 대한 관점, 다문화교육에 대한 태도와 다문화 교수효능감과의 관계)

  • Kim, Na Rim;Kwon, Yi Jeong
    • Korean Journal of Childcare and Education
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    • v.10 no.5
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    • pp.83-100
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    • 2014
  • This study aims to explore the relationships between preschool teachers' beliefs about the purpose of multicultural education and their attitudes and teaching efficacy with respect to multicultural education. For this purpose, 296 teachers, who were working at kindergartens and daycare centers, were chosen for this study and the survey method was used to collect data. The TMAS (Teacher Multicultural Attitude Survey), Multicultural Teaching Efficacy Scale, and teachers' belief about the purpose of multicultural education were used to evaluate teachers' multicultural-related variables. To analyze the data, frequency measurements, percentile, one-way ANOVA, and Pearson's product moment correlation coefficient were used. Through this study, these findings were found: 1) Teachers most perceive human relations as the purpose of multicultural education. 2) There is no relationship between the belief in multicultural education and the attitudes and teaching efficacy with respect to multicultural education. However, The attitudes about multicultural curriculum show meaningful differences, depending on the teachers' beliefs about the purpose of multicultural education. 3) The attitudes and teaching efficacy with respect to multicultural education are strongly related to each other. These findings are discussed with respect to the necessity of multicultural education curriculum development for preschool teachers.