• Physical Therapy Korea
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• v.20 no.4
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• pp.55-64
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• 2013

The first purpose was to identify the plantar pressure distributions (peak pressure, pressure integral time, and contact area) during level walking, and stair ascent and descent in asymptomatic flexible flatfoot (AFF). The second purpose was to investigate whether peak pressure data during level walking could be used to predict peak pressure during stair walking by identifying correlations between the peak pressures of level walking and stair walking. Twenty young adult subjects (8 males and 12 females, age $21.0{\pm}1.7$ years) with AFF were recruited. A distance greater than 10 mm in a navicular drop test was defined as flexible flatfoot. Each subject performed at least 10 steps during level walking, and stair ascent and descent. The plantar pressure distribution was measured in nine foot regions using a pressure measurement system. A two-way repeated analysis of variance was conducted to examine the differences in the three dependent variables with two within-subject factors (activity type and foot region). Linear regression analysis was conducted to predict peak pressure during stair walking using the peak pressure in the metatarsal regions during level walking. Significant interaction effects were observed between activity type and foot region for peak pressure (F=9.508, p<.001), pressure time integral (F=5.912, p=.003), and contact area (F=15.510, p<.001). The regression equations predicting peak pressure during stair walking accounted for variance in the range of 25.7% and 65.8%. The findings indicate that plantar pressures in AFF were influenced by both activity type and foot region. Furthermore the findings suggest that peak pressure data during level walking could be used to predict the peak pressure data during stair walking. These data collected for AFF can be useful for evaluating gait patterns and for predicting pressure data of flexible flatfoot subjects who have difficulty performing activities such as stair walking. Further studies should investigate plantar pressure distribution during various functional activities in symptomatic flexible flatfoot, and consider other predictors for regression analysis.

• Journal of Pharmaceutical Investigation
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• v.40 no.3
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• pp.193-200
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• 2010

The objective of this study was to investigate the effects of sample preparation, HPLC conditions and peak measurement methods upon determining progesterone content of poly-d,l-lactide-co-glycolide microspheres. A series of the microspheres with different formulations was first prepared. To determine their actual drug contents, the microspheres were dissolved in tetrahydrofuran and diluted with various amounts of methanol to precipitate the polymer. After removal of polymeric precipitates, the filtrates were subject to HPLC analysis under versatile experimental conditions. Interestingly, the composition of a sample solution (e.g., the ratio of methanol to tetrahydrofuran) affected the magnitudes of both peak fronting and peak broadening of progesterone. Its peak became broader and more asymmetrical at lower methanol:tetrahydrofuran ratios. Furthermore, its peak height was influenced by the proportion of tetrahydrofuran in a sample solution. Such problems encountered with tetrahydrofuran were exacerbated when a larger volume of the sample solution was injected onto an analytical column. Under our experimental conditions a peak area measurement provided more accurate and reliable determination of progesterone content in various microspheres than a peak height determination. Optimizing the composition of a sample solution, HPLC chromatographic conditions and peak analysis methods was a prerequisite to an accurate determination of progesterone encapsulated within microspheres.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.67 no.10
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• pp.1278-1285
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• 2018

For saving electricity bill, energy storage system(ESS) is being installed in factories, public building and commercial building with a Time-of-Use(TOU) tariff which consists of demand charge(KRW/kW) and energy charge(KRW/kWh). However, both of peak reduction and ESS special tariff are not considered in an analysis of initial cost payback period(ICPP) on ESS. Since it is difficult to reflect base rate by an amount of uncertain peak demand reduction during mid-peak and on-peak periods in the future days. Therefore, the ICPP on ESS can be increased. Based on this background, this paper presents the advanced analysis method for the ICPP on ESS. In the proposed algorithm, the representative days of monthly electricity consumption pattern for the amount of peak reduction can be found by the k­means clustering algorithm. Moreover, the total expected energy costs of representative days are minimized by optimal daily ESS operation considering both peak reduction and the special tariff through a mixed-integer linear programming(MILP). And then, the amount of peak reduction becomes a value that the sum of the expected energy costs for 12 months is maximum. The annual benefit cost is decided by the amount of annual peak reduction. Two simulation cases are considered in this study, which one only considers the special tariff and another considers both of the special tariff and amount of peak reduction. The ICPP in the proposed method is shortened by 18 months compared to the conventional method.

• Korean Journal of Metals and Materials
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• v.48 no.12
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• pp.1123-1129
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• 2010

In order to apply the Sievert's type automatic apparatus to thermal analysis of hydrogen absorbing materials, the dehydrogenation of the Mg-H system was investigated. As the initial wt% of hydrogen was increased to 4.4, the peak temperature of evolution rate shifted to higher temperature. However, with the initial wt% of hydrogen higher than 4.4, peak temperature of evolution rate did not change. The peak temperatures of evolution rate obtained by automatic apparatus were almost the same as those measured by a manual apparatus. As the heating rate was increased, the peak temperatures increased; the peak temperatures for heating rates 1, 2 and 3 K/min were 664, 687 and 702 K, respectively. The activation energy for the decomposition of Mg hydride was 101 kJ/mol. The Sievert's type automatic apparatus can be successively applied to the thermal analysis of metal hydride.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.38 no.2
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• pp.6-12
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• 2001

When CBR source traffics are loaded to ATM switch and broadband network termination, CTD values of ATM switch and broadband network termination are measured and then the values of CTD in the domestic region arc estimated. The estimation values of CTD satisfy the objective of CTD in the domestic region allocated by allocation rules of 1.356. The peak-to-peak CDV allocation method based On Chernoff accumulation method is proposed and applied to the nodes of national portion. From the result of numerical analysis, the proposed method is more accurate than the equal allocation method for peak -to-peak CDV in case that the CDVs at each node and the number of ATM nodes on the path increase.

• Genomics & Informatics
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• v.18 no.4
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• pp.42.1-42.9
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• 2020

Chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-Seq) is a powerful technology to profile the location of proteins of interest on a whole-genome scale. To identify the enrichment location of proteins, many programs and algorithms have been proposed. However, none of the commonly used peak calling programs could accurately explain the binding features of target proteins detected by ChIP-Seq. Here, publicly available data on 12 histone modifications, including H3K4ac/me1/me2/me3, H3K9ac/me3, H3K27ac/me3, H3K36me3, H3K56ac, and H3K79me1/me2, generated from a human embryonic stem cell line (H1), were profiled with five peak callers (CisGenome, MACS1, MACS2, PeakSeq, and SISSRs). The performance of the peak calling programs was compared in terms of reproducibility between replicates, examination of enriched regions to variable sequencing depths, the specificity-to-noise signal, and sensitivity of peak prediction. There were no major differences among peak callers when analyzing point source histone modifications. The peak calling results from histone modifications with low fidelity, such as H3K4ac, H3K56ac, and H3K79me1/me2, showed low performance in all parameters, which indicates that their peak positions might not be located accurately. Our comparative results could provide a helpful guide to choose a suitable peak calling program for specific histone modifications.

• Journal of Electrical Engineering and Technology
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• v.12 no.4
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• pp.1427-1434
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• 2017

Since the late 2000s, there has been growing preparation in South Korea for a sudden reunification of South and North Korea. Particularly in the power industry field, thorough preparations for the construction of a power infrastructure after reunification are necessary. The first step is to estimate the peak load demand. In this paper, we suggest a new peak demand estimation methodology by integrating existing correlation analysis methods between economic indicators and power generation quantities with a power supply interruption model in consideration of power consumption patterns. Through this, the potential peak demand and actual peak demand of the Nation, which experiences power supply interruption can be estimated. For case studies on North Korea after reunification, the potential peak demand in 2015 was estimated at 5,189 MW, while the actual peak demand within the same year was recorded as 2,461 MW. The estimated potential peak demand can be utilized as an important factor when planning the construction of power system facilities in preparation for reunification.

• Journal of Food Hygiene and Safety
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• v.14 no.1
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• pp.67-75
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• 1999

The new approach using the Peak Pattern Method was conducted for the analysis of polychlorinated biphenyls (PCBs) from the papers or paper products to provide certain hygienic data for the recycled papers as well as white papers. The height of the each peak, obtained from the PCBs standards, was transformed to the spectrum to compare with that of the samples. In addition to the results of the single PCBs standards, the pattern of mixed PCBs standards with the adequate concentration and ratios were obtained prior to the analysis of the paper samples. The test showed excellent repetition within 5% variation, and the recoveries of PCBs ranged from 92% to 97%. The PCBs, considered as a hazard material, were analyzed using the Peak Pattern Method from six different types of paper samples including the roll tissue. It could not find the same pattern of the PCBs peaks from all of the paper samples.

• Journal of Power Electronics
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• v.10 no.6
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• pp.680-685
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• 2010

Although LLC resonant converters have the advantages of a wide operation range and high efficiency, the lack of an analytical solution for the peak gain makes it difficult to optimize the resonant tank design, when considering not only the normal condition but also the holdup time requirement. In this paper, based on a mathematical analysis of a LLC resonant converter at the peak gain point, an analytical solution for the peak gain has been developed. By using the developed analytical solution, the peak gain with given resonant tank parameters can be obtained. To confirm the validity of the developed analytical solution, simulations and experimental results are compared.

• Smart Structures and Systems
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• v.18 no.2
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• pp.293-315
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• 2016

Seismic isolation is often used in protecting mission-critical structures including hospitals, data centers, telecommunication buildings, etc. Such structures typically house vibration-sensitive equipment which has to provide continued service but may fail in case sustained accelerations during earthquakes exceed threshold limit values. Thus, peak floor acceleration is one of the two main parameters that control the design of such structures while the other one is peak base displacement since the overall safety of the structure depends on the safety of the isolation system. And in case peak base displacement exceeds the design base displacement during an earthquake, rupture and/or buckling of isolators as well as bumping against stops around the seismic gap may occur. Therefore, obtaining accurate peak floor accelerations and peak base displacement is vital. However, although nominal design values for isolation system and superstructure parameters are calculated in order to meet target peak design base displacement and peak floor accelerations, their actual values may potentially deviate from these nominal design values. In this study, the sensitivity of the seismic performance of structures equipped with linear and nonlinear seismic isolation systems to the aforementioned potential deviations is assessed in the context of a benchmark shear building under different earthquake records with near-fault and far-fault characteristics. The results put forth the degree of sensitivity of peak top floor acceleration and peak base displacement to superstructure parameters including mass, stiffness, and damping and isolation system parameters including stiffness, damping, yield strength, yield displacement, and post-yield to pre-yield stiffness ratio.