• Title/Summary/Keyword: pH agent

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Tumor Uptake Rate of Alkaline $^{99m}Tc-DMSA$ in Walker Carcinosarcoma 256 Bearing Wistar Rats (염기성 $^{99m}Tc-DMSA$의 Walker 256 암육종 이식백서에서 종양섭취율에 관한 연구)

  • Lim, S.M.;Hong, S.W.;Awh, O.D.;Lee, M.C.;Koh, C.S.
    • The Korean Journal of Nuclear Medicine
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    • v.22 no.1
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    • pp.65-76
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    • 1988
  • High affinity complexes for the tumor were obtained by changing pH and composition in the preparation of $^{99m}Tc-DMSA$. The purpose of this study was to investigate the tumor affinity, and in vitro and in vivo characteristics of these complexes. The results obtained were as follows; 1) Tumor imaging agent was formed successfully at pH $6.0\sim9.0$ and renal imaging agent at pH $2.0\sim5.0$. 2) The serum protein binding of $^{99m}Tc-DMSA$ was $89.1\sim92.8%$ at pH $2.0\sim5.0$ and $11.8\sim30.5%$ at pH $6.0\sim9.0$ respectively, and it was not changed with time. 3) The T 1/2 of tumor affinity complex in blood between 3 and 6 hours after injection was $187{\pm}29$ minutes $(mean{\pm}SD)$. 4) In the blood, the radioactivity was mainly in the plasma, and less than 1% was in the cellular components. 5) In the Walker carcinosarcoma 256 bearing Wistar rats, the radioactivity in the kidney increased, and decreased in the skeleton with time. The radioactivity in the tumor showed the peak in 6 hours after injection and decreased thereafter. 6) In the tumor cell, the radioactivity localized mainly in the cytosol, the soluble fraction of the cytoplasm. This study provides the basic knowledge about tumor affinity and usefulness of $^{99m}Tc-DMSA$ in the diagnosis of malignant disease.

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Adsorption Analysis of Fluorescent Whitening Agent on Cellulosic Fibers by Zeta Potential Measurement (지료의 제타전위 측정을 통한 형광증백제의 흡착 평가)

  • Lee, Ji Young;Kim, Eun Hea;Kim, Chul Hwan;Park, Jong Hye
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.47 no.6
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    • pp.106-112
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    • 2015
  • Many researchers have proposed analytical methods to measure the adsorption of di-sulpho fluorescent whitening agents (D-FWAs), but practical methods for D-FWA utilization in an actual paper mill have not been established. In particular, the D-FWA adsorption behavior must be monitored in paper mills to ensure the effective use of D-FWAs. This study used the zeta-potential of pulps as an indicator of the adsorption behavior of a D-FWA. We identified the relationship between the actual adsorption of the D-FWA and the zeta-potential of the pulps as a function of D-FWA addition. zeta-potential measurements were then used to analyze the D-FWA adsorption behavior under different conditions of pulp type, conductivity, and pH. The actual adsorption of a D-FWA was proportional to the ${\Delta}zeta-potential$ of the pulps (i.e., the difference between the zeta-potential of a pulp containing no D-FWA and one containing the D-FWA). The ${\Delta}zeta-potential$ of the pulps was therefore adopted for adsorption analysis. A higher adsorption of the D-FWA was observed onto Hw-BKP than onto Sw-BKP because of the shorter fiber length and higher fines content of Hw-BKP. A high conductivity and an acidic pH decreased the D-FWA adsorption because of direct effects of high ion concentrations and low pH on the D-FWA solubility. Therefore, a D-FWA must be added to Hw-BKP under low conductivity conditions and at neutral or alkaline pH to optimize the D-FWA adsorption.

The Quality Characteristics of Kimchi as Affected by the Addition of Xanthan Gum (증점안정제로 사용한 Xanthan Gum첨가가 김치의 품질에 미치는 영향)

  • Park, Woo-Po
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.31 no.3
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    • pp.423-427
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    • 2002
  • Xanthan gum (XG) was investigated for use as a thickening and stabilizing agent in kimchi during fermentation at 10$\^{C}$. The mixing ratios of XG to salted Chinese cabbage were 0.1, 0.3 and 0.5%. Quality characteristics of kimchi such as pH, titratable acidity, reducing sugar content and microbial loads were measured. pH and reducing sugar content showed abrupt decreases after 5 day lag time until 20 days, while titratable acidity steadily increased during fermentation. The addition with 0.5% XG retarded the change rates of pH and titratable acidity showing the slowest change. Kimchi samples added with 0.1% and 0.3% XG maintained a higher reducing sugar content during the whole fermentation period of 30 days. Microbial loads showed an abrupt increase from 5 to 10 days, and maintained a nearly same load thereafter. Kimchi sample added with 0.3% XG showed better scores in color, aroma and taste.

Adsorption Characteristics of Al (III), Ni (II), Sm (III) Ions on Resin with Styrene Hazardous Material in Reinforcement Water Fire Extinguishing Agent

  • Kim, Joon-Tae
    • Journal of Integrative Natural Science
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    • v.6 no.3
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    • pp.151-157
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    • 2013
  • The ion exchange resins were synthesized from 1-aza-18-crown-6 macrocyclic ligand attached to styrene (2th petroleum in 4th class hazardous material) divinylbenzene (DVB) copolymer with crosslinks of 1%, 6%, and 15% by substitution reaction. These synthetic resins were confirmed by chlorine content, elementary analysis, surface area, and IR-spectrum. The object of this study was to seperate the metal ion absorbed in reinforcement water fire extinguishing agent. As the results of the effects of pH, equilibrium arrival time, and crosslink of synthetic resin on metal ion adsorption for resin adsorbent, the metal ions were showed high adsorption at pH 3 or over and adsorption equilibrium of metal ions was about 2 hours. In addition, adsorption selectivity for the resin in water was the order of Al (III) > Ni (II) > Sm (III) ions, adsorbability of the metal ions was in the crosslinks order of 1%, 6%, and 15%.

Effect of AcNPV Infection Conditions on Recombinant Protein Production in Spodoptera frugiperda 21 Cells (AcNPV 감염 조건이 Spodoptera frugiperda 21 세포에서의 재조합 단백질 생산에 미치는 영향)

  • 김지선;이기웅;강석권;양재명;정인식
    • Microbiology and Biotechnology Letters
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    • v.21 no.5
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    • pp.504-510
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    • 1993
  • The effect of AcNPV infection conditions such as serum concentration, pH, CaCl2, lysosomotropic agent, cell density at infection, agitation, aeration and nutritional supplementattion on recombinant protein production in Spodoptera frugiperda 21 cells was investigated using tissue culture flask, bottle and spinner flask. It was shown that serum, CaCl2, pH and cell density at infection affected recombinant production. The lysosomotropic agent did not significantly influence recombinant protein production.

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Adsorption Characteristic of Mg(II), Al(III), Pb(II) Metal Ions on Cryptand Ion Exchange Resin from Water Fire Extinguishing Agent (물 소화약제로부터 Cryptand 이온교환수지의 Mg(II), Al(III) 및 Pb(II) 흡착특성)

  • Kim, Joon-Tae;Kim, Kwan-Chun
    • Journal of environmental and Sanitary engineering
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    • v.23 no.1
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    • pp.57-65
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    • 2008
  • Resins were synthesized with 1-aza-15-crown-5 macrocyclic ligand attached to styrene(dangerous matter) divinylbenzene(DVB) copolymer with crosslink of 1, 2, 6 and 15% by substitution reaction. The synthesis of these resins was confirmed by content of chlorine, element analysis, and IR-spectrum. The effects of pH, time and crosslink on adsorption of metal ion from water fire extinguishing agent by the synthetic resin adsorbent were investigated. The metal ion was showed fast adsorption on the resins above pH 3. The optimum equilibrium time for adsorption of metallic ions was about two hours. The adsorption selectivity determined in water was in increasing order of $Mg^{2+}>Al^{3+}>Pb^{2+}$. The adsorption was in the order of 1, 2, 6, and 15% crosslink resin.

Properties of Gel-like Compounds Containing Flammable Solvents (Gel형 인화성 용제 Compound의 특성)

  • 강영구;김정훈
    • Journal of the Korean Society of Safety
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    • v.18 no.3
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    • pp.94-100
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    • 2003
  • Gel-like compounds containing flammable solvents were prepared to use fur cleaning agents in field of innovative industries and general purposes. And experiments were conducted to improve the defects of liquified flammable solvents from the view point of safety and health hazards. Flammable solvents used in this study were several single component flammable solvents(turpentine oil, N-methyl-2-pyrrolidone(NMP), d-limonene) and multi component flammable solvent(gasoline and ethanol). For gelation of flammable solvents, commercially Known as Aerosil(equation omitted) 200 fumed silica and triethanolamine(TEA) were used as gelation agent dispersant. The analyses on properties of gel-like compounds was studied by gelation and viscosity test pH test, volatility test and differential scanning calorimetry(DSC) measurement. The experimental results indicate that gel-like compounds containing flammable solvents have pH stability, high viscosity, volatile organic compounds(VOC) control by the decrease of volatility and odor component generation, fluidity control etc. From the experimental values, it can be predicted that the safety in the working place is improved by manufacturing flammable solvents into gel-like compounds.

A Study on the Corrosion Effects by Addition of Complexing Agent in the Copper CMP Process

  • Kim, Sang-Yong;Kim, Nam-Hoon;Kim, In-Pyo;Chang, Eui-Goo;Seo, Yong-Jin;Chung, Hun-Sang
    • Transactions on Electrical and Electronic Materials
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    • v.4 no.6
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    • pp.28-31
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    • 2003
  • Copper CMP in terms of the effect of slurry chemicals (oxidizer, corrosion inhibitor, complexing agent) on the process characteristics has been performed. Corrosion inhibitors, benzotriazole (BTA) and tolytriazol (TTA) were used to control the removal rate and avoid isotropic etching. When complexing agent is added with H$_2$O$_2$ 2 wt% in the slurry, the corrosion rate was presented very well. In the case of complexing agent, it was estimated that the proper concentration is 1 wt%, because the addition of tartaric acid to alumina slurry causes low pH and the slurry dispersion stability become unstable. There was not much change of the removal rate. It was assumed that BTA 0.05 wt% is suitable. Most of all, it was appeared that BTA is possible to be replaced by TTA. TTA was distinguished for the effect among complexing agents.

Reduction of Stem Inside-cavity and Improvement of Flower Quality in Chrysanthemum 'Baekma' by pH Stabilization and Foliar Spray of Ethephon (양액 pH 안정화와 에세폰 살포에 의한 국화 '백마'의 줄기동공 경감과 절화품질 향상)

  • Hwang, In Taek;Cho, Kyung Chul;Kim, Hee Gon;Ki, Gwang Yeon;Yoon, Bong Ki;Choi, Kyung Ju;Lim, Jin Hee;Choi, Sung Ryul;Shin, Hak Ki
    • FLOWER RESEARCH JOURNAL
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    • v.18 no.4
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    • pp.238-243
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    • 2010
  • This study was conducted to investigate effects of nutrient solution pH control agent and foliar spray of ethephon on the reduction of stem inside-cavity and improvement of flower quality in chrysanthemum 'Baekma'. Changes of pH in nutrient solution as affected by the kind of pH control agent showed more settled pattern in the plot of KOH treatment than in others. Plant growth and development such as cut flower length, leaf numbers, cut flower weight and petal number were the greatest in the plot of KOH. However, the size and area of stem cavity was large in KOH rather than $KHCO_3$. As changes in the absorbing patterns of mineral elements as affected by nutrient solution pH control agent in closed system, contents of total nitrate, phosphorus, potassium and calcium by $KHCO_3$ was absorbed into the plant less than KOH, so that it remained a lot of mineral element residues rather than KOH in closed system. Plant growth as affected by the foliar spray of ethephon showed growth retardation effect in the plot of solution diluted to 1 : 500 and growth promotion effect in the plot of solution diluted to 1 : 1,000 or 1 : 2,000. The number of petals was the best in the plot of foliar spray of ethephon solution diluted to 1 : 1,000 before flowering at 45 days showing 331 petals compared to control showing 302 petals. The size and area of stem cavity as affected the foliar spray of ethephon was smaller 1 mm and 7%, respectively, in the plot of solution diluted to 1 : 2,000 before flowering at 30 days than in control. Therefore, treating pH stabilization using KOH after floral initiation stage with the foliar spray of ethephon solution diluted to 1 : 2,000 before flowering at 30 days would help to reduce stem cavity size and improve flower quality in hydroponically grown chrysanthemum 'Baekma'.