• Journal of Korean society of Dental Hygiene
• /
• v.22 no.1
• /
• pp.1-9
• /
• 2022

Objectives: This study was conducted to find scaling patients' oral health belief and satisfaction by applying Comprehensive Dental Hygiene Care (CDHC) process. Methods: From July 1 to September 20, 2020, the data about 182 patients who had scaling in dental clinics and hospitals had been collected and analyzed. For data analysis, SPSS Statistics 22.0 was applied to conduct frequency analysis, chi-square, t-test, One way ANOVA and Pearson's correlation analysis. Results: Regarding oral health behavior, in the CDHC group 92.4% used oral care products (p<0.001), and 67.4% regularly visited dental clinics for oral care (p<0.001). Regarding the oral health belief according to general characteristics, in the CDHC group, persons aged '50-65' scored 2.4 (the highest), and were significantly different from those aged '20-29' as the result of post-hoc analysis (p<0.001). Regarding the oral health belief of the CDHC group according to oral health behavior, the scaling cycle '3 months' scored the highest (p<0.05). The patients' satisfaction had high correlations with benefit (p<0.01) and Importance (p<0.05) as the sub factors of the oral health belief of the CDHC group. Conclusions: CDHC positively influenced scaling patients' oral health belief and satisfaction. Therefore, it is necessary to expand CDHC, as the medium to improve oral health belief and satisfaction, to clinical settings.

• Journal of Preventive Medicine and Public Health
• /
• v.55 no.1
• /
• pp.88-97
• /
• 2022

Objectives: This study investigated the determinants of depression in adolescents and young adults. Methods: The present study analyzed data from the 2018 Indonesia Basic Health Survey (Riset Kesehatan Dasar; RISKESDAS). The study subjects were adolescents (15-17 years old) and young adults (18-24 years old). In total, 64 179 subjects were included. Univariable, bivariable, and multivariable logistic regression analyses were performed to determine associations between youths' characteristics, risky behavior, chronic disease, parents' health, and youths' depression. Results: The prevalence of depression was 5.1% in adolescents and 5.6% in young adults. The risk factors for depression in adolescents were being women (adjusted odds ratio [aOR], 3.53; 95% confidence interval [CI], 2.89 to 4.30; p<0.001), an ex-smoker (aOR, 2.99; 95% CI, 2.10 to 4.25; p<0.001), or a current smoker (aOR, 2.60; 95% CI, 1.97 to 3.44; p<0.001); consuming alcohol (aOR, 2.00; 95% CI, 1.33 to 3.01; p=0.001), having a chronic disease (aOR, 2.64; 95% CI, 1.41 to 4.96; p=0.002); maternal depression (aOR, 2.47; 95% CI, 1.97 to 3.09; p<0.001); and paternal depression (aOR, 2.63; 95% CI, 1.98 to 3.50; p<0.001). In young adults, the risk factors were being women (aOR, 2.23; 95% CI, 1.82 to 2.75; p<0.001) or an ex-smoker (aOR, 2.47; 95% CI, 1.67 to 3.67; p<0.001), consuming alcohol (aOR, 2.42; 95% CI, 1.89 to 3.09; p<0.001), maternal depression (aOR, 3.12; 95% CI, 2.54 to 3.84; p<0.001), and paternal depression (aOR, 2.80; 95% CI, 2.17 to 3.63; p<0.001). Conclusions: Being women, smoking, drinking alcohol, having a chronic disease, and having a parent with depression were crucial factors associated with youth depression. Mental health screening, prevention, and treatment should involve collaboration among primary healthcare, schools, universities, professionals, and families.

• Bulletin of the Korean Chemical Society
• /
• v.29 no.8
• /
• pp.1539-1544
• /
• 2008

A polymeric micelle, based on the poly(benzyl-L-histidine)-b-poly(ethylene glycol) (polyBz-His-b-PEG) diblock copolymer, was designed as a tumor-specific targeting carrier. The micelles (particle size: 67-80 nm, critical micelle concentration (CMC); 2-3 $\mu$g/mL) were formed from the diafilteration method at pH 7.4, as a result of self-assembly of the polyBz-His block at the core and PEG block on the shell. Removing benzyl (Bz) group from polyBz-His block provided pH-sensitivity of the micellar core; the micelles were physically destabilized in the pH range of pH 7.4-5.5, depending on the content of the His group free from Bz group. The ionization of His group at a slightly acidic pH promoted the deformation of the interior core. These pHdependent physical changes of the micelles provide the mechanism for pH-triggering anticancer drug (e.g., doxorubicin: DOX) release from the micelle in response to the tumor’s extracellular pH range (pH 7.2-6.5).

• Journal of the Korean Applied Science and Technology
• /
• v.32 no.2
• /
• pp.202-214
• /
• 2015

Stimuli-responsive biomaterials that alter their function through sensing local molecular cues may enable technological advances in the fields of drug delivery, gene delivery, actuators, biosensors, and tissue engineering. In this research, pH-responsive hydrogel which is comprised of dimethylaminoethyl methacylate (DMAEMA) and 2-hydroxyethyl methacrylate (HEMA) was synthesized for the effective delivery of doxorubicin (Dox) to breast cancer cells. Cancer and tumor tissues show a lower extracellular pH than normal tissues. DMAEMA/HEMA hydrogels showed significant sensitivity by small pH changes and each formulation of hydrogels was examined by scanning electron microscopy, mechanical test, equilibrium mass swelling, controlled Dox release, and cytotoxicity. High swelling ratios and Dox release were obtained at low pH buffer condition, low cross-linker concentration, and high content of DMAEMA. Dox release was accelerated to 67.3% at pH 5.5 for 6-h incubation at $37^{\circ}C$, while it was limited to 13.8% at pH7.4 at the same time and temperature. Cell toxicity results to breast cancer cells indicate that pH-responsive DMAEMA/HEMA hydrogels may be used as an efficient matrix for anti-cancer drug delivery with various transporting manners. Also, pH-responsive DMAEMA/HEMA hydrogels may be useful in therapeutic treatment which is required a triggered release at low pH range such as gene delivery, ischemia, and diabetic ketoacidosis.

• Journal of Environmental Health Sciences
• /
• v.31 no.1
• /
• pp.94-98
• /
• 2005

This study was carried out to provide radon concentration and exposure in building. The average radon concentrations of building was measured 1.37 pCi/L in basement, 0.95 pCi/L in 1st layer, 0.74 pCi/L in 2nd layer, 0.56 pCi/L in 3rd layer, and 0.4 pCi/L in 4th layer, respectively. The average radon concentration of basement was measured the higher than any other stairs. Daily average distribution of radon concentrations in building shown that radon concentrations measured in morning at 8hr was the highest value. Monthly average distribution of radon concentrations shown 0.28 ${\pm}$ 0.17 pCi/L in April and 0.82 pCi/L in December that was the highest value. The average concentrations of radon was measured 0.38pCi/L in spring. 0.44 pCi/L in summer, 0.53 pCi/L in autumn, and 0.67 pCi/L in winter, respectively. This result shown that the average concentrations of radon in winter was the higher than any other seasons. That reasons was supposed that effect of number of exchanges and using air conditions was the higher in summer than winter.

• Food Science and Preservation
• /
• v.17 no.2
• /
• pp.208-213
• /
• 2010

We sought to optimize parboiled rice preparations with respect to nutritional composition and to compare the physicochemical properties of polished, glutinous rices and Olbyossal (parboiled rice). Crude lipid contents (all w/w) were: brown glutinous rice (1.92%) > Olbyossal (1.13%) > glutinous rice (1.08%) > polished rice (0.32%). The crude ash content of Olbyossal was greater than that of polished rice. There was no significant difference in crude protein level between Olbyossal and polished rice. Total dietary fiber content (all figures are w/w) was higher in Olbyossal (3.79%) than in polished rice (1.67%). With respect to mineral content, P (249.16 mg%), K (144.67 mg%), Na (35.41 mg%), and Mg (30.24 mg%) levels were higher in Olbyossal than in polished rice. There was no significant difference in fatty acid or amino acid content between polished rice and Olbyossal. The L value (lightness) of Olbyossal was lower than that of polished rice but the hardness of Olbyossal was greater.

• International Journal of Oral Biology
• /
• v.33 no.2
• /
• pp.59-64
• /
• 2008

This study was designed to investigate the changes in the properties of the neuronal setm cells or progenitor cells associated with age-related decline in neurogenesis of the hippocampal dentate gyrus (DG). Active whole cells cycle marker Ki67 (a marker of whole cell cycle)-positive and S phase marker bromodeoxyuridine (BrdU)-positive. Neural stem cells gradually were reduced in the hippocampal subgranular zone (SGZ) in an age-dependant manner after birth (from P1 month to P1 year). The ratio of BrdUpositivecells/Ki67-positive cells was gradually enhanced in an age-dependent manner. The ratio of Ki67-positive cells/accu-mulating BrdU-positive cells at 3 hrs after BrdU injection was injected once a day for consecutive 5 days gradually decreased during ageing. TUNEL- and caspase 3 (apoptotic terminal caspase)-positive cells gradually decreased in the dentate SGZ during ageing and immunohistochemical findings of glial fibrillary acid protein (GFAP) were not changed during ageing. NeuN, a marker of mature neural cells, and BrdU-double positive cells gradually decreased in an age-dependent manner but differentiating ratio and survival rate of cells were not changed at 4 wks after BrdU injection once a day for consecutive 5 days. The number of BrdU-positive cells migrated from the hippocampal SGZ into granular layer and its migration speed was gradually declined during ageing. These results suggest that the adult neurogenesis in the mouse hippocampal DG gradually decrease through reducing proliferation of neural stem cells accompanying with cells cycle change and reduced cells migration rather than changes of differentiation.

• Korean Journal of Organic Agriculture
• /
• v.19 no.4
• /
• pp.553-563
• /
• 2011

This experiment was conducted to determine the effect of nattokinase (NK) additives on milk production and composition, and blood metabolites in dairy cows. The two kinds of nattokinase with high fibrinolytic activity were produced by two strains of bacteria, Bacillus amyloliquefacines (NK1) and Bacillus subtilis (NK2). Total fifteen Holstein cows (average $1.83{\pm}0.37$ parity; average milk yield $23.2{\pm}3.2$ kg/d) were randomly assigned to three treatments (5 animals per treatment). Cows were fed TMR supplemented with 0g, 100g and 100g for control, NK1 and NK2 treatment, respectively for 4 weeks. Milk yield was significantly higher (p<0.05) for NK1 (22.89 kg/d) than for control (21.07 kg/d) and NK2 (21.36 kg/d). Somatic cell counts in NK treatments were significantly lower than that in control group (58,000 vs. 21,000 and 35,000 cells/ml, control vs. NK1 and NK2). Serum ALT levels in all treatment were similar to the range of 32.00~35.83 IU/L, but AST levels in NK1 (85.67 IU/L) was significantly decreased compared with those in control and NK2 (121.67 and 117.67 IU/L respectively). Serum T-CHO levels in NK1 (145.33 mg/dl) was significantly decreased (p<0.05) compared with that in control (179.00 mg/dl) and NK2 (176.17 mg/dl). This finding showed that NK1 additives could possibly have a positive effect in lactation performance of mid-lactation dairy cows by increasing milk yield, reducing somatic cell count, improving liver function and decreasing cholesterol in blood.

• Child Health Nursing Research
• /
• v.16 no.3
• /
• pp.175-183
• /
• 2010

Purpose: The purpose of this study was to identify child-rearing practices and parenting efficacy of Marriage-Immigrant Women. Methods: The research design was a descriptive study using self-report questionnaires. Data were collected from May 16 to December 30, 2008. Marriage-immigrant women (n=186) were recruited in G Province, C Province and P city. Descriptive statistics, t-test, ANOVA, and correlation coefficients with SPSS 14.0 were used to analyze the data. Results: The mean score for child-rearing practices was $40.61{\pm}6.67$ and there were significant differences in child-rearing practices by nationality, and Korean language ability. The mean score for parenting efficacy was $67.67{\pm}12.14$ and there were significant differences in parenting efficacy by age, nationality, marital period, age of first child and Korean language ability. There were significant positive correlations between child-rearing practices and parenting efficacy (r=.227, p=.002). Conclusion: In this study, marriage-immigrant women showed a moderate level of child-rearing practices and parenting efficacy. Because child-rearing is mainly the mother's role in the family, knowledge, attitudes to child-rearing and parenting efficacy of mothers influence child-rearing practices and these then, affect children's health. Therefore child-rearing educational programs for marriage-immigrant women should be developed to support the mothers' child-rearing practices and improve parenting efficacy.

• The Journal of Information Technology
• /
• v.7 no.1
• /
• pp.155-161
• /
• 2004

During normal machine operation, partial discharge(PD) measurements were performed with turbine generator analyzer(TGA) in imitation stator winding of high voltage motors. The motor was energized to 4.47kV, 6.67, respectively. Applied voltage to Imitation winding was used two voltage level, 4.47[kV] and 6.67[kV]. Motors having imitation stator winding were installed with 80pF capacitive couplers at the terminal box. Case of PD Pattern regarding applied voltage phase angel, the PD patterns were displayed two dimensional and three dimensional. TGA summarizes each plot with two quantities such as the normalized quantity number(NQN) and the peak PD magnitude(Qm). As the result, we could discrimidate using TGA the difference of internal and surface discharge for imitation stator winding. We have used the other technique, in order to feature extraction of faulty signals on stator winding, Daubechies Discrete wavelet transform and Harmonics analysis(FFT) about faulty signals.