• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.129-130
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• 1998

In this paper, We designed the ECG-NIBP-$SpO_2$ patient monitor. This production can measure Electrocardiograph, Heart Rate, Noninvasive Blood Pressure, and Oxygen Saturation for Noninvasive Mehod and can display each information. These informations were implemented by the electrodes of ECG part, the cuff of NIBP module and the finger probe with light sensor of $SpO_2$ without injection of needle or catheter. In addition, We developed a new analysis algorithm and measurement technique for NIBP and $SpO_2$ to observe patient's conditions correctly.

• Journal of Dental Anesthesia and Pain Medicine
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• 제21권4호
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• pp.357-361
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• 2021

Methemoglobinemia is a blood disorder in which an abnormal amount of methemoglobin is produced, and prilocaine is one of the drugs that can cause this disorder. The maximum recommended dose of prilocaine is 8 mg/kg. We report a case of methemoglobinemia caused by the administration of 4.2 mg/kg of prilocaine without other methemoglobinemia-inducing drugs during general anesthesia. A 17-year-old girl with hyperthyroidism and anemia was scheduled to undergo maxillary sinus floor elevation and tooth extraction. The patient's peripheral oxygen saturation (SpO₂) decreased from 100% at arrival to 95% after receiving prilocaine with felypressin following induction of general anesthesia. However, the fraction of inspired oxygen was 0.6. Blood gas analysis showed that the methemoglobin level was 3.8% (normal level, 1%-2%), fractional oxygen saturation was 93.9%, partial pressure of oxygen was 327 mmHg, and arterial oxygen saturation was 97.6%. After administration of 1 mg/kg of methylene blue, her SpO₂ improved gradually to 99%, and the methemoglobin value decreased to 1.2%. When using prilocaine as a local anesthetic, it is important to be aware that methemoglobinemia may occur even at doses much lower than the maximum recommended dose.

• Child Health Nursing Research
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• 제4권2호
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• pp.245-254
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• 1998

Prematurity is the main cause for respiratory disorders in neonates. The goal in respiratory management is to maintain respiration with adequate oxygenation. Chest vibration(CV) prior to on dotracheal suctioning(ETS) has been arbitrarily applied to ventilated premature infants without the scientific evaluation of its safety and efficacy. A repeated measure within subjects experimental study was conducted to investigate the effects of CV prior to 875 on oxygenation and lung secretions in twenty-one ventilated premature infants. The independent variable was the type of research protocol, the control type (275 without C.V) and t he intervention(ETS with CV). The dependent variables were oxygen saturation(SpO₂), heart rate (HR), measured by pulse oximeter, and the amount of lung secretions measured in gram. The results showed there was no difference in SpO₂ responses regardless CV employed before ETS. But there was a significant difference in HR responses between the control and the intervention, even without clinical significance. There was a significant difference in the amount of lung secretions retrieved during ETS with CV, compared to ETS without CV. This study suggested the safety of CV by demonstrating no clinically significant changes in SpO₂ and HR in premature infants. The efficacy of CV could be supported by the increases in the amount of sputum during ETS with CV compared to ETS without CV in premature infants.

• Archives of Plastic Surgery
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• 제48권4호
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• pp.457-461
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• 2021

Background Pedicled perforator flaps can present postoperative complications similar to those encountered in free flap surgery. Beyond a clinical evaluation, there is still no reliable technical aid for the early prediction of vascular issues. The aim of this study was to assess the support of near-infrared spectroscopy technology as an intraoperative tool to anticipate postsurgical flap ischemia. Methods We prospectively enrolled 13 consecutive patients who were referred to our hospital from March 2017 to July 2018 and required a reconstructive procedure with a pedicled fasciocutaneous perforator flap. We measured flap peripheral capillary oxygen saturation (SpO₂) in each patient with a Somanetics INVOS 5100C Cerebral/Somatic Oximeter (Medtronic), both before and after transposition. Patient demographics, operative data, and complications were then recorded during the following 6 months. We analyzed the data using the Wilcoxon signed-rank test and linear regression. Results The mean flap SpO₂ before and after transposition was 92%±3% and 78%±19%, respectively. The mean change in SpO₂ was 14%±17%, with a range of 0% to 55%. The change in saturation and mean saturation ratio were significantly different between patients with and without postoperative flap necrosis. Conclusions An immediate quantitative analysis of flap peripheral capillary SpO₂ after transposition has never before been described. In our experience, an intraoperative drop in SpO₂ equal to or greater than 15%-20% predicted vascular complications in pedicled perforator flaps. Conversely, flap size and rotation angle were not correlated with the risk of flap necrosis.

• 대한소아치과학회지
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• 제27권4호
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• pp.494-498
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• 2000

진정요법하의 치과진료에서 환자의 상태를 지속적으로 감시하는 것은 매우 중요하다. 여러 방법 중 가장 널리 사용되는 것 중 Pulse Oximeter가 있다. Pulse Oximeter는 비침습적 방법으로 계속해서 동맥혈액의 산소포화도를 측정할 수 있도록 고안된 장치로서 기기에 나타나는 산소포화도$(SpO_2)$는 실제로 측정한 동맥혈액의 산소포화도$(SaO_2)$와 거의 일치하는 것으로 알려져 있다. 본 진료실에 있는 세종류의 Pulse Oximeter를 이용하여 한 환자에게 동시에 두 개의 기기를 적용하였을 경우, 산출값을 상호 비교한 결과, 짧은(3회) 맥박수를 평균하는 기기가 낮은값이 나왔으며, 다른 두개의 Pulse Oximeter와 유의한 차이가 있는 것으로 밝혀졌다. 짧은 맥박수를 평균하는 기기는 반응이 빠르나, 산소포화도의 값이 작게 산출되고, 외부의 신호에 더욱 민감하여, 오류가 존재할 가능성 또한 높다. 기기의 특성을 알아, 술자는 적절한 기기를 선택하는 것이 중요하다.

• 대한임베디드공학회논문지
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• 제8권5호
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• pp.273-283
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• 2013

The traditional medical equipments are devices used by medical professionals but not used in public environment. Common people, however, require light-weight medical devices to make healthcare for themselves nowadays. Those medical devices are used to monitor personal health status such as blood pulse, blood pressure, diabetes. Also, some of them are operated in mobile environment called u-healthcare. This paper implements a portable healthcare system composed of $SpO_2$(Saturation of Partial Pressure Oxygen) sensors and a gateway for detecting hypoxemia during people's leasure activity such as climbing or hiking. The $SpO_2$ sensor is designed as watch style to support dynamic exercise and the gateway is designed as necklace style to support the elderly. The result of a performance evaluation shows that the performance of the $SpO_2$ sensor using reflection technology is not lower than that of a clairvoyant styled $SpO_2$ sensor.

• Tuberculosis and Respiratory Diseases
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• 제84권2호
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• pp.125-133
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• 2021

Background: The coronavirus disease (COVID-19) can manifest in a range of symptoms, including both asymptomatic systems which appear nearly non-existent to the patient, all the way to the development of acute respiratory distress syndrome (ARDS). Specifically, COVID-19-associated pneumonia develops into ARDS due to the rapid progression of hypoxia, and although arterial blood gas analysis can assist in halting this deterioration, the current environment provided by the COVID-19 pandemic, which has led to an overall lack of medical resources or equipment, has made it difficult to administer such tests in a widespread manner. As a result, this study was conducted in order to determine whether the levels of oxygen saturation (SpO₂) and the fraction of inhaled oxygen (FiO₂) (SF ratio) can also serve as predictors of ARDS and the patient's risk of mortality. Methods: This was a retrospective cohort study conducted from February 2020 to Mary 2020, with the study's subjects consisting of COVID-19 pneumonia patients who had reached a state of deterioration that required the use of oxygen therapy. Of the 100 COVID-19 pneumonia cases, we compared 59 pneumonia patients who required oxygen therapy, divided into ARDS and non-ARDS pneumonia patients who required oxygen, and then investigated the different factors which affected their mortality. Results: At the time of admission, the ratios of SpO₂, FiO₂, and SF for the ARDS group differed significantly from those of the non-ARDS pneumonia support group who required oxygen (p<0.001). With respect to the predicting of the occurrence of ARDS, the SF ratio on admission and the SF ratio at exacerbation had an area under the curve which measured to be around 85.7% and 88.8% (p<0.001). Multivariate Cox regression analysis identified that the SF ratio at exacerbation (hazard ratio [HR], 0.916; 95% confidence interval [CI], 0.846-0.991; p=0.029) and National Early Warning Score (NEWS) (HR, 1.277; 95% CI, 1.010-1.615; p=0.041) were significant predictors of mortality. Conclusion: The SF ratio on admission and the SF ratio at exacerbation were strong predictors of the occurrence of ARDS, and the SF ratio at exacerbation and NEWS held a significant effect on mortality.

• The Korean Journal of Pain
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• 제9권2호
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• pp.374-379
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• 1996

Background: Recently, improvements in drug administration technology have intensified interest in the treatment of postoperative pain. this has resulted in increased use of continuous intravenous infusion of opioid and epidural opioid as alternative to traditional intramuscular administration of opioid. The goal of this study, therefore, was to document the effects of pain control and side effects following continuous intravenous infusion of morphine or meperidine and intramuscular meperidine following cesarean section. Methods: The vital signs, pain score, oxygen saturation and side effects were compared in 150 patients receiving continuous intravenous infusion of morphine, 30 ${\mu}g/kg/hr$ (n=50, group 1); continuous intravenous infusion of meperidine, 150 ${\mu}g/kg/hr$ (n=50, group 2); or intramuscular meperidine, 50mg/every 6hrs (n=50, group 3). Results: VAS (Visual Analogue Scale) was significantly decreased after 30 minutes of administration in all three groups and was significantly lower at 1 hour, but higher at 6 hours in group 3 than two other groups. Severe desaturation episode, defined as $SpO_2$<90%, occurred in the group 3(0.2%). Moderate desaturation episodes, defined as $SpO_2$ 91~95%, occurred more in group 3 than in group 1 and 2 (17.4% vs. 10.4%, 8.2%). The incidence of side effects were similar among three groups. Conclusion: The continuous infusion of opioid was more effective and safe method of postoperative pain control than traditional intramuscular injection.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2011년도 추계학술대회
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• pp.462-465
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• 2011

맥박산소측정기는 비침습적으로 사용자의 혈중 산소포화도(percentage oxygen saturation of haemoglobin: SpO2)를 측정 및 모니터링 하는 기기이다. 맥박산소측정기를 포함한 대부분의 개인건강기기 (Personal Health Device: PHD) 들은 데스크톱 컴퓨터에 비해 제한된 리소스를 가지므로, 측정한 데이터를 근거리의 매니저 (스마트폰, PC)에 전송하고, 매니저를 통해 원격의 모니터링 서버로 전송하는 방식을 사용한다. 따라서 개인건강기기와 매니저 간의 통신 프로토콜은 상호호환성의 관점에서 중요한 연구 분야이다. 이에 본 논문에서는 개인건강기기에 관한 국제 표준인 ISO/IEEE 11073 (X73) 프로토콜 기반 산소포화도 전송 에이전트의 설계 결과를 제시한다. 본 논문의 에이전트는 맥박산소측정기가 측정한 사용자의 산소포화도 및 맥박 수를 X73 메시지로 생성하여 매니저에게 전송하는 임베디드 프로그램으로 세션핸들러, 메시지 핸들러, 그리고 메모리 핸들러로 구성된다. 세션 핸들러는 원격 모니터링 서버와의 통신 세션 연결, 해제를 담당하고, 메시지 핸들러는 X73 메시지의 생성 및 해석을 담당한다. 메모리 핸들러는 맥박산소측정기 메모리에 저장된 맥박 및 산소포화도를 추출한다. 본 논문의 산소포화도 전송 에이전트를 사용함으로써, 맥박산소측정기는 x73 표준을 따르는 여러 매니저들과의 통신이 가능하게 되며, 이를 통해 맥박산소측정기와 매니저 간 상호호환성을 보장할 수 있다.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 춘계학술대회
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• pp.267-270
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• 1997

Oxygen saturation is an important parameter in clinical fields; fetal monitoring, apnea, emergency medicine etc. Because of monitoring patients continuously, pulse oximeter that measures oxigen saturation non-invasively is regarded attentively. But, though research about accuracy of signal extraction has been developed, it actually plays a supplementary part in hospital for not trusting the principle of measurement by clinicians. In this paper focusing on these things, first we suggested simple mathematical modelling on separating do components, ac components andnoise components in optical signal transmitted from fingertip or earlobe, and then we considered oxygen saturation computing algorithm using integral ratio of pulsating components. Last, we analyzed its effect by comparing received data.