• 제목/요약/키워드: over-fitting

검색결과 347건 처리시간 0.025초

림프구의 미소핵을 지표로 영광 원자력발전소 주변 사육 돼지의 방사선 생물학적 평가 (Radiobiological Evaluation in Pig Bred in the Vicinity of Yeonggwang Nuclear Power Station Using Micronuclei in Cytokinesis-blocked Lymphocyte)

  • 김세라;강창모;김성호
    • 한국임상수의학회지
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    • 제21권3호
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    • pp.286-290
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    • 2004
  • Cytogenetic and hematological analysis was performed in peripheral blood of pig in the vicinity of Yeonggwang nuclear power station and control area. The frequency of micronuclei (MN) in peripheral blood lymphocytes from pig was used as a biomarker of radiobiological effects resulting from exposure to environmental radiation. An estimated dose of radiation was calculated by a best fitting linear-quadratic model based on the radiation-induced MN formation from the swine lymphocytes exposed in vitro to radiation over the range from 0 Gy to 4 Gy. MN rates in lymphocytes of pig from Yeonggwang nuclear power station and control area were 10.60/1,000 and 11.10/1,000, respectively. There were no significant differences in MN frequencies and hematological values in pig between Yeonggwang and control area. The study indicates that the MN assay in lymphocyte of pig is a rapid, sensitive and accurate method that can be used to monitor a large population exposed to radiation.

A FRACTIONAL-ORDER TUMOR GROWTH INHIBITION MODEL IN PKPD

  • Byun, Jong Hyuk;Jung, Il Hyo
    • East Asian mathematical journal
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    • 제36권1호
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    • pp.81-90
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    • 2020
  • Many compartment models assume a kinetically homogeneous amount of materials that have well-stirred compartments. However, based on observations from such processes, they have been heuristically fitted by exponential or gamma distributions even though biological media are inhomogeneous in real environments. Fractional differential equations using a specific kernel in Pharmacokinetic/Pharmacodynamic (PKPD) model are recently introduced to account for abnormal drug disposition. We discuss a tumor growth inhibition (TGI) model using fractional-order derivative from it. This represents a tumor growth delay by cytotoxic agents and additionally show variations in the equilibrium points by the change of fractional order. The result indicates that the equilibrium depends on the tumor size as well as a change of the fractional order. We find that the smaller the fractional order, the smaller the equilibrium value. However, a difference of them is the number of concavities and this indicates that TGI over time profile for fitting or prediction should be determined properly either fractional order or tumor sizes according to the number of concavities shown in experimental data.

CASTELNOUVO-MUMFORD REGULARITY OF GRADED MODULES HAVING A LINEAR FREE PRESENTATION

  • Ahn, Jeaman
    • 충청수학회지
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    • 제22권4호
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    • pp.777-787
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    • 2009
  • In this paper we investigate the upper bound on the Castelnuovo-Mumford regularity of a graded module with linear free presentation. Let M be a finitely generated graded module over a polynomial ring R with zero dimensional support. We prove that if M is generated by elements of degree $d{\geq}0$ with a linear free presentation $$\bigoplus^p{R}(-d-1)\longrightarrow^{\phi}\bigoplus^q{R}(-d){\longrightarrow}M{\longrightarrow}0$$, then the Castelnuovo-Mumford regularity of M is at most d+q-1. As an important application, we can prove vector bundle technique, which was used in [11], [13], [17] as a tool for obtaining several remarkable results.

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A Superior Description of AC Behavior in Polycrystalline Solid Electrolytes with Current-Constriction Effects

  • Lee, Jong-Sook
    • 한국세라믹학회지
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    • 제53권2호
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    • pp.150-161
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    • 2016
  • The conventional brick-layer model is not satisfactory either in theory or in practice for the description of dispersive responses of polycrystalline solid electrolytes with current-constriction effects at the grain boundaries. Parallel networks of complex dielectric functions have been shown to successfully describe the AC responses of polycrystalline sodium conductors over a wide temperature and frequency range using only around ten model parameters of well-defined physical significance. The approach can be generally applied to many solid electrolyte systems. The present work illustrates the approach by simulation. Problems of bricklayer model analysis are demonstrated by fitting analysis of the simulated data under experimental conditions.

Hexagonal 인서트용 열간압출 금형설계 (Die Design of Hot Extrusion for Hexagonal Insert)

  • 권혁홍;이정로
    • 한국공작기계학회논문집
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    • 제11권1호
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    • pp.32-37
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    • 2002
  • The use of hexagonal ceramic inserts for copper extrusion dies offers significant technical and economic advantages over other forms of manufacture. In this paper the data on the loading of the tools is determined from a commercial FEM package as the contact stress distribution on the die-workpiece interface and as temperature distributions in the die. This data can be processed as load input data for a finite element die-stress analysis. Process simulation and stress analysis are thus combined during the design and a data exchange program has been developed that enables optimal design of the dies taking into account the elastic deflections generated in shrink fitting the die inserts and that caused by the stresses generated in the process. The stress analysis of the dies is used to determine the stress conditions on the ceramic insert by considering contact and interference effects under both mechanical and thermal loads.

Hexagonal 인서트용 열간압출 금형설계 (Design of Hot Extrusion Dies for Hexagonal Insert)

  • 권혁홍;이정로
    • 한국공작기계학회:학술대회논문집
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    • 한국공작기계학회 2001년도 춘계학술대회 논문집(한국공작기계학회)
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    • pp.72-77
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    • 2001
  • The use of hexagonal ceramic inserts for copper extrusion dies offers significant technical and economic advantages over other forms of manufacture. In this paper the data on the loading of the tools is determined from a commercial FEM package as the contact stress distribution on the die-workpiece interface and as temperature distributions in the die. This data can be processed as load input data for a finite element die-stress analysis. Process simulation and stress analysis are thus combined during the design, and a data exchange program has been developed that enables optimal design of the dies taking into account the elastic deflections generated in shrink fitting the die inserts and that caused by the stresses generated in the process. The stress analysis of the dies is used to determine the stress conditions on the ceramic insert by considering contact and interference effects under both mechanical and thermal loads.

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적층 스크린의 압력강하 및 열전달 특성 (Pressure Drop and Heat Transfer Characteristics of Multi-Layer Screen)

  • 송태호;안철우;김창기;고현진
    • 대한기계학회논문집B
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    • 제24권3호
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    • pp.419-425
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    • 2000
  • Multiple layer of wire screen is widely used in many compact devices to filter particulates and to heat or cool fluids. However, data of flow resistance and heat transfer through such layers are rare to find and thus they are experimentally investigated in this study. Compressed air is made to flow through it to find the Ergun constants over a wide range of the Reynolds number. Also, unsteady heating of the wire screen is performed to find the equivalent heat transfer coefficient between the screen and the air by fitting the unsteady air temperature. The obtained coefficients are expressed in terms of the Reynolds number and the Prandtl number.

An alternative method for estimation of annual extreme wind speeds

  • Hui, Yi;Yang, Qingshan;Li, Zhengnong
    • Wind and Structures
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    • 제19권2호
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    • pp.169-184
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    • 2014
  • This paper presents a method of estimation of extreme wind. Assuming the extreme wind follows the Gumbel distribution, it is modeled through fitting an exponential function to the numbers of storms over different thresholds. The comparison between the estimated results with the Improved Method of Independent Storms (IMIS) shows that the proposed method gives reliable estimation of extreme wind. The proposed method also shows its advantage on the insensitiveness of estimated results to the precision of the data. The volume of extreme storms used in the estimation leads to more than 5% differences in the estimated wind speed with 50-year return period. The annual rate of independent storms is not a significant factor to the estimation.

Total Wood Volume Equations for Tectona Grandis Linn F. Stands in Gujarat, India

  • Tewari, Vindhya Prasad;Singh, Bilas
    • Journal of Forest and Environmental Science
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    • 제34권4호
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    • pp.313-320
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    • 2018
  • Tectona grandis (teak) is one of the most important timber species worldwide and India is one of the major teak growing countries. Though some volume equations were developed for teak in India but the models developed were neither evaluated using robust statistical criteria nor validated. Hence, the objective of this study was to develop statistically tested appropriate volume equation to predict total wood volume (over- and under-bark) for teak trees in Gujarat. A total of 41 trees with age varying from 15 to 33 years and diameter at breast height (dbh) from 7.3 to 30.8 cm were felled for the purpose. Linear and non-linear equations were used to model the relationship of the total wood volume with respect to dbh and total height. The equations tested mostly fitted well to the data. Model evaluation and validation indicated that models should be calibrated with local data for greater accuracy in the prediction.

2 Key Bridge에 대한 연구 (A Study on the 2 Key Bridge)

  • 박종희
    • 대한치과기공학회지
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    • 제22권1호
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    • pp.57-67
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    • 2000
  • The 2 key bridge system has been developed to make crownless bridges without damaging sound teeth. Strong bridge work of single or multiple pontics is possible for replacing both anterior and posterior teeth. It is incresingly considerde to be unacceptable, by dentists as well as patients, to fully grind down healthy elements in order fit a conventional bridges. Because this technique uses a combination of hole and adhesive fitting, it has a number of adventages over etched bridges and conventional bridges: - In comparison with conventional bridges, hardly and healthy dental tissue is sacrificed - Due to the lack of crown edges there is no periodontal pressure, as is the case with conventional bridges - The treatment procedure is straight forward and involves less time than conventional bridges. - The treatment is largely resiverable and repairable

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