• Title/Summary/Keyword: osteoporosis

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Community periodontal index and osteoporosis relevance (지역사회치주지수와 골다공증 관련성)

  • Jang, Yun-Jung;Kim, Nam-Song
    • Journal of Korean society of Dental Hygiene
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    • v.12 no.5
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    • pp.943-952
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    • 2012
  • Objectives : The purpose of this study was to examine the impact of the systemic osteoporosis of Korean adults on their periodontal diseases and CPI index based on the data of their systemic osteoporosis. Methods : The third-year raw data of the 4th 2009 National Health & Nutrition Survey that turned out to be representative and reliable were utilized. The subjects in this study were 7,285 adults who were over the age of 19 and got both of health and dental checkups. As for data analysis, the statistical packages PASW 19.0 and SAS 9.0 were employed. Results : The most periodontal diseases were found in those who had osteoporosis in the entire parts, entire femur, femoral neck and spiral bone, but there was no significant relationship between periodontal diseases and osteoporosis. As for the connections between peridontal diseases and osteoporosis, the adults who had femoral neck osteoporosis had a 2.057-fold less bone mass than those who had a normal bone density in this part, and the former's periodontal diseases increased in proportion to that. There was consequently a statistically significant relationship between the two(p<0.05). Among the prevalence factors of osteoporosis, a lower entire femur bone mineral density led to a lower CPI index(p<0.01), and a lower femoral neck bone mineral density led to a higher CPI index(p<0.05). Thus, there was a significant relationship between osteoporosis and the oral health indicator. Conclusions : The above-mentioned findings confirmed that in terms of the relationship among the periodontal diseases, CPI index and osteoporosis of Korean adults, a higher risk of osteoporosis affected the increase of chronic periodontal diseases.

A Study on the Effect of Osteoporosis Knowledge, Osteoporosis Preventive Behaviors and Self-Efficacy of Middle Aged Women on Health-Related Quality of Life (중년기 여성의 골다공증 지식 및 예방행위, 자기효능감이 건강관련 삶의 질에 미치는 영향)

  • Jeong, Yun Ju;Kim, Yun Ah;Kwon, Young Chae
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.2
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    • pp.107-116
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    • 2021
  • Purpose : To examine the relationship among osteoporosis knowledge, osteoporosis preventive behaviors, self-efficacy and health-related quality of life of middle aged women and to find out factors which influence health-related quality of life. Methods : For study subjects, female patients aged 40 to 64 and hospitalized at the surgical wards of two general hospitals in G city were conveniently sampled. The data have been collected from January 11 to March 10, 2018. Data were analyzed by descriptive statistics, t-test, ANOVA, Scheffe's test, Pearson's correlation coefficient, and multiple regression. Results : The average score of osteoporosis knowledge was 12.50±3.47, the average score of osteoporosis preventive behaviors was 44.96±8.16 and the average score of osteoporosis self-efficacy was 40.38±8.07. The factors influencing EQ-5D Index in health-related quality of life were comorbidity, osteoporosis preventive behaviors, osteoporosis knowledge and average monthly income, which could account for health-related quality of life at 18.0%. The factors influencing EQ-5D VAS were osteoporosis preventive behaviors, self-efficacy, osteoporosis knowledge and age of menarche, which could account for health-related : Higher osteoporosis knowledge, osteoporosis preventive behaviors and self-efficacy, the better the subjects health-related quality of life. Therefore, as a way to promote health-related quality of life of middle aged women, the constant development and the application of a program which may promote osteoporosis knowledge, osteoporosis preventive behaviors and self-efficacy are needed.

Knowledge, Health Belief, and Self-efficacy Related to Osteoporosis (일개 신도시 지역의 골다공증 지식, 건강신념, 자기 효능감에 관한 연구)

  • Shin Su Jin;Shin Kyung Rim;Yi Hye Ryeon;Ju Su Kyung
    • Journal of Korean Academy of Nursing
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    • v.35 no.5
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    • pp.850-857
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    • 2005
  • Purpose: This research was conducted to examine the relationship of knowledge, health beliefs, and self-efficacy on osteoporosis. Method: The design of this study was a correlative design. The subjects were 1,615 Korean adults over the age of 20 registered in a new town and participants were asked to fill in a questionnaire developed by Kim, Horan & Gendler (1991), translated into Korean. Results: 1) The subjects recorded an average score of 1l.10 on osteoporosis knowledge. The average scores on the osteoporosis health beliefs was 15.68 for perceived susceptibility and the respondents recorded an average score of 40.40 for osteoporosis self-efficacy. 2) There were statistically significant differences in the degree of osteoporosis knowledge, self-efficacy and health belief according to gender, age, scholastic achievement, marital state, and jobs. 3) There were statistically significant positive correlations between osteoporosis knowledge and self-efficacy. Conclusion: According to these results, an osteoporosis education program improving not only knowledge but also self-efficacy and health beliefs should be developed and applied to decrease the perception of barriers to exercise and intake of calcium.

Patients' Perceptions of Korean Medicine Treatment for Osteoporosis in a Clinical Trial of an Osteoporosis Herbal Medicine Drug: a Qualitative Study (골다공증 한약제제 임상시험 참여자의 골다공증 한의치료에 대한 인식 : 질적 연구)

  • Ahn, Jae-hyun;Cho, Ye-eun;Kim, Ji-hye;Lee, Seung-hoon;Kang, Jung-won;Lee, Jae-dong
    • The Journal of Internal Korean Medicine
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    • v.38 no.2
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    • pp.201-216
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    • 2017
  • Objective: This research aimed to understand patients' perceptions of Korean medicine treatment for osteoporosis in a clinical trial setting. Methods: Ten patients participating in a clinical trial of a herbal medicine drug for osteoporosis were invited to an interview. Data were collected by in-depth interviews and patient observations. This qualitative study adopted the case study research method, and within-case and cross-case analyses were conducted. Results: A model of the patients' osteoporosis management planning was derived from the study. The results showed that the patients' perceptions of osteoporosis were derived from their knowledge and experience during diagnosis and treatment of the condition. Two groups of patients were recognized: those who overlooked the importance of osteoporosis and those who recognized the importance of osteoporosis. Before making treatment decisions about osteoporosis, the patients evaluated the treatment options and weighed the advantages and disadvantages of each option. When evaluating their treatment, the patients combined their knowledge and experience of Korean and western medicine treatments. Their experience of participating in the clinical trial influenced the management planning of osteoporosis. Two major reasons for low compliance with osteoporosis treatment were ignorance of the disease and insufficient information provided by doctors. Conclusion: The results of this qualitative study pointed to four strategies that could be employed to improve accessibility to Korean medicine treatment for osteoporosis: the dissemination of comprehensive information on osteoporosis in the clinic and mass media, promotion of Korean medicine therapies for osteoporosis, management of clinical trial participants, and insurance coverage for Korean medicine.

Clinical Analysis about Treatment of Myofascial Pain Syndrome(MPS) with Sweet Bee Venom on Hand Paresthesia based on Thoracic Outlet Syndrome (흉곽출구증후군으로 손 저림을 호소하는 환자들에 대한 Sweet BV의 아시혈적 치료 효능 관찰)

  • Oh, Sung-Won;Kim, Byoung-Woo;An, Joong-Chul;Yoon, Hye-Chul;Park, Jae-Seuk;Kwon, Ki-Rok
    • Journal of Pharmacopuncture
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    • v.13 no.2
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    • pp.85-92
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    • 2010
  • Objectives: The objective of this study was to compare the effects of Sweet Bee Venom(Sweet BV) Therapy between the hand paresthesia patients with Osteoporosis and without Osteoporosis. Methods: This study was carried out to established the clinical criteria of hand parethesia. The patients who had past history of diabeics, neuropathy induced by alcohol or drug and was positive on Myofacial Pain Syndrome Theory were excluded. 32 patients who had hand paresthesia related with unknown-reason was selected by the interview process. And the effects of treatment were analyzed using VAS score before treatment, after treatment, after 1 month and after 3 months. Results and conclusion: After treatment, While Osteoporosis group decrease from $64.81{\pm}7.81$ to $27.21{\pm}7.32$, Non-Osteoporosis group decrease from $58.76{\pm}1.43$ to $24.74{\pm}3.81$ by VAS scores. and After 3 months, While Osteoporosis group increase from $27.21{\pm}7.32$ to $54.96{\pm}9.40$, Non Osteoporosis group increase from $24.74{\pm}3.81$ to $32.43{\pm}5.57$. Non-Osteoporosis group was accordingly more effective than Osteoporosis group after 3 months. So Sweet BV therapy for hand numbness patients without Osteoporosis was e effective than patients with Osteoporosis.

Socioeconomic Disparities in Osteoporosis Prevalence: Different Results in the Overall Korean Adult Population and Single-person Households

  • Kim, Jungmee;Lee, Joongyub;Shin, Ju-Young;Park, Byung-Joo
    • Journal of Preventive Medicine and Public Health
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    • v.48 no.2
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    • pp.84-93
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    • 2015
  • Objectives: The present study was conducted in order to examine the association between socioeconomic status (SES) and osteoporosis prevalence in Korea and to assess whether different associations are found in single-person households. Methods: A cross-sectional population-based study was conducted using the Korea National Health and Nutrition Examination Survey, from 2008 to 2011. The study subjects were people aged ${\geq}50$ years with osteoporosis as defined by bone mineral density. Multivariate logistic models were used to estimate prevalence odds ratios (pORs) and 95% confidence intervals (CIs). Gender differences in the likelihood of osteoporosis were analyzed based on household income, education level, and residential area. Results: There were 8221 osteoporosis patients aged ${\geq}50$ years, of whom 927 lived in single-person households. There was a gender-specific association between osteoporosis prevalence and all three SES factors that we analyzed: income, education, and residential area. After adjusting for age, SES, and health behaviors, including body mass index (BMI), low household income was only significantly associated with osteoporosis in men, whereas education level had an inverse relationship with osteoporosis only in women (p=0.01, p<0.001, respectively). However, after controlling for age and BMI, rural residency was only associated with osteoporosis in women living in single-person households (pOR, 1.59; 95% CI, 1.05 to 2.43). Conclusions: The Korean adult population showed a gender-specific relationship between SES and osteoporosis prevalence, with a different pattern found in single-person households.

Network Analysis of Herbs that are Frequently Prescribed for Osteoporosis with a Focus on Oasis Platform Research (골다공증 다빈도 처방과 구성 약물의 네트워크 분석 - 오아시스 검색을 중심으로)

  • Shin, Seon-mi;Ko, Heung
    • The Journal of Internal Korean Medicine
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    • v.42 no.4
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    • pp.628-644
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    • 2021
  • Objectives: This study analyzed, through network analysis and data mining analysis, the relationship between herbs used in osteoporosis prescriptions, diversified the analysis of osteoporosis-related prescriptions, and analyzed the combination of herbs used in osteoporosis-related prescriptions. Methods: The prescriptions used in osteoporosis treatment and experiments were established by conducting a full survey of the papers published by the OASIS site. A database for osteoporosis-related prescriptions was established, herbs were extracted, and the frequency of frequent herbs and prescriptions were investigated using Excel (MS offices ver. 2013). Using the freeware R version 4.0.3 (2020-10-10), igraph, and arules package, network analysis was performed in the first second of prescription composition. Results: Among the osteoporosis-related prescriptions, the most studied prescriptions are as follows.: Yukmijihwang-tang (六味地黃湯) and Samul-tang (四物湯). In the osteoporosis prescription network, herbs with connection centrality, proximity centrality, mediation centrality, and eigenvector centrality appeared in the order of Rehmanniae Radix Preparata, Angelicae Gigantis Radix, Poria Sclerotium, Paeoniae Radix, and Glycyrrhizae Radix et Rhizoma. After extracting the herbal combination network, including the corresponding herbs, and clustering it, it can be divided into drugs of the Yukmijihwang-tang (六味地黃湯) series and the Samul-tang (四物湯). Conclusions: This study could assist researchers in diversifyingy formula analysis in future studies. Moreover, the herbal combination used in osteoporosis prescriptions could be used to search for osteoporosis prescriptions in other databases or to create a new prescription.

The Association between Medication Use for Dyslipidemia and Osteoporosis (국내 성인환자에서 이상지질혈증 약물치료와 골다공증 상관성)

  • Lee, Hansol;Kim, Jongyoon;Rhew, Kiyon
    • Korean Journal of Clinical Pharmacy
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    • v.31 no.4
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    • pp.278-284
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    • 2021
  • Background: Osteoporosis is a disease that affects the quality of life and imposes a high socioeconomic burden. Studies have reported that statins, a HMG CoA reductase inhibitor, have a positive or negative effect on osteoporosis. The purpose of this study was to analyze the correlation between statins and osteoporosis risk. Methods: We used the total patient sample data of the Health Insurance Review and Assessment Service (HIRA-NPS-2018). We analyzed the prevalence of osteoporosis in adult patients of Korea who were diagnosed with dyslipidemia and were prescribed statins at the same time. The odds ratio (OR) according to the intensity and type of statin was used to confirming the prevalence. Results: Among the 1,138,899 patients included in the study, 143,895 patients used statins and 27,524 patients (19.13%) were diagnosed with osteoporosis in the statin group. The OR value of statin group was 0.96 (95% CI 0.94-0.98), confirming that the prevalence of osteoporosis decreased, and a significant decrease was seen in all statin intensity. Some of the moderate-intensity statins rather increased the prevalence of osteoporosis, but atorvastatin and rosuvastatin obtained positive results at both medium- and high-intensity doses, and lovastatin, a low-intensity statin, showed the greatest reduction in the prevalence of osteoporosis. Conclusion: We found that the prevalence of osteoporosis was reduced in the statin group, and there was a constant correlation regardless of gender or age. However, a large, prospective, double-blind and randomized study is needed for a long period of time to demonstrate the effectiveness of statins.

Interleukin-10-Producing B Cells Help Suppress Ovariectomy-Mediated Osteoporosis

  • Yuhua Wang;Wei Zhang;Seong-Min Lim;Li Xu;Jun-O Jin
    • IMMUNE NETWORK
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    • v.20 no.6
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    • pp.50.1-50.11
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    • 2020
  • Osteoporosis is prevalent in elderly women and it may cause dental implant failure. In particular, estrogen deficiency in postmenopausal women leads to higher rates of osteoporosis prevalence. Immune cell-mediated effects involving the development of osteoporosis have been studied previously; however, the role of IL-10-producing regulatory B (B10) cells in osteoporosis is largely unclear. Here, we examined the role of B10 cells in osteoporosis. C57BL/6 mice were subjected to ovariectomy (OVX). Fifteen weeks after OVX surgery, the first molar of the right maxillary was extracted, and twenty-four weeks after OVX surgery, serous progression of osteoporosis was observed in the alveolar bone. Moreover, the proportion of CD19+CD5+CD1dhigh regulatory B cells, B10, and CD4+CD25+FoxP3+ regulatory T cells from the spleen of OVX mice decreased during the progression of osteoporosis, compared to controls. In contrast to regulatory cells, IL-17-producing Th (Th17) cell levels were increased in OVX mice. Adoptive transfer of B10 cells to OVX mice led to a decrease in Th17 cell abundance and inhibited the development of osteoporosis in the alveolar bone from OVX mice. Thus, our results suggest that B10 cells may help suppress osteoporosis development.

Factors Related to Osteoporosis Prevalence in Postmenopausal Women (폐경 후 여성의 골다공증 유병 관련 요인)

  • Chae, Hyun Ju
    • Journal of muscle and joint health
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    • v.28 no.2
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    • pp.91-101
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    • 2021
  • Purpose: This study was conducted to identify factors related to osteoporosis prevalence in postmenopausal women. Methods: This study was a secondary analysis research using data from the Eighth Korea National Health and Nutrition Examination Survey (KNHANES VIII-1), 2019, which were downloaded from the KNHANES website. The subjects of this study were 1,791 postmenopausal women who participated in the KNHANES VIII-1, 2019. Data analysis was performed using the IBM SPSS 21.0 program and complex sample design analysis was performed considering factors such as weight, cluster, and strata. Results: Osteoporosis prevalence of in postmenopausal women was 17.5%. Factors related to osteoporosis prevalence were age (65~74 years old, ≥75 years old), house income (low), household type (one-person household), postmenopausal period (10~19 years), drinking (non-drinking). Conclusion: Interventions for osteoporosis prevention and management in postmenopausal women need to focus on women less than 10 years after menopause and one-person household women. Furthermore, it is necessary to expand bone density testing for the early detection of osteoporosis in postmenopausal women.