• The Korea Journal of Herbology
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• v.23 no.1
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• pp.45-51
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• 2008

Objectives : For the purpose of developing Korean herbalogy of the plants belonging to Polypodiaceae in Korea, the literatures of the successive generations have been thoroughly investigated to prepare this article. The results of this study are as follows : Methods : The examined herbalogical books and research papers which published at home and abroad. Results : 1. There are totaled to 8 genera and 24 species in Polypodiaceae in Korea and among them medicinal plants are 7 genera, 11 species, some 46% in total. 2. Pyrrosia genus is main kind enough that it has 5 species among 24 species in Polypodiaceae, of which medicinal plants are 3 species. 3. The herb is the main medicinal parts if medicinal plants in the Polypodiaceae, which is used in 9 species. 4. According to nature and flavor of medicinal plants in the Polypodiaceae, they were classified into cool 9 species, and cold 5; sweet taste 10 and bitter taste 8 in the order. 5. According to meridian propism of medicinal plants in the Polypodiaceae, they were classified into bladder meridian 5 species, lung meridian 4 species. 7.The number of toxic species in the Polypodiaceae was examined to be none. Conclusions : There are totaled to 8 genera and 24 species in Polypodiaceae in Korea and among them medicinal plants are 7 genera, 11 species, some 46% in total.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.10a
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• pp.102-102
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• 2018

Protaetia Brevitarsis Seulensis(white grub) has been traditionally used as medicinal stuff to treat blood stasis, occlusion of menstruation, tetanus and liver cancer in Asian countries (Korea, Japan, China, Taiwan, India and Myanmar). Especially, Donguibogam, which is traditional korean medicinal book, described the white grub as traditional medicine to treat hepatic diseases and vascular disorders. The white grub has been considered as highly nutritional food. The major constituents of white grub are rich in protein, healthy fats, iron, calcium. Recent studies announced that white grub has hepatoprotective effect and anti-microbacterial effect. However, the immuno-enhancing effect of white grub extracts in RAW 264.7 macrophage cells has not been studied yet. In this study, the various concentrations of white grub extract were examined to find immuno-enhancing effects on RAW 264.7 cells. Cytotoxicity was determined by MTT assay and immuno-enhancing effect of white grub extract was investigated by measuring nitric oxide (NO) production compared with only lipopolysaccharide (LPS) treatment. White grub extracts (0.001 - 10 mg/ml) did not show cytotoxicity. Additionally, white grub extracts (0.001 - 1mg/ml) had Immuno-enhancing effect on RAW 264.7 cells compared with only LPS treated group. These results might be provided proof to develop beneficial immuno-enhancing material for human health.

• Journal of Society of Preventive Korean Medicine
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• v.6 no.1
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• pp.15-35
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• 2002

This study was conducted to provide basic data for policy of Oriental medicine by analyzing community resident's consciousness of taking herb medicine and its related factors. Data were collected from 1478 residents from March 2, 2001 to May 31, 2001. The results of this study are summarized as follows. 1) The rate of experience of taking herb medicine was 85.2%(88.2% of 'male'; 82.5% of 'female'). It appeared to be significantly higher in the groups of 'the married', 'housewife', and 'Buddhist'. As the age increased, so the rate of experience of taking herb medicine was significantly high. 2) In case of purpose of taking herb medicine, taking herb medicine as a restorative(66.8%) was much higher than taking it as a curative medicine. 3) 52.1% of the respondents satisfied with the effect of herb medicine. The groups of 'male', 'older age', 'residents in a big city', 'insurant in company', and 'the employed' showed significantly high rate in satisfying with herb medicine than the other groups. 4) According to the reason for preferring herb medicine, 36.7% of the respondents preferred herb medicine because the herb medicine was effective, while 27.8% preferred it because its side effect was low. 16.7% preferred it because persons around them recommended it. 5) 42.6% of the respondents did not want to take the herb medicine because the price of the herb medicine was high. Also 20.6% of the respondents did not want to take herb medicine because it is uneasy to take herb medicine. 15.8% did not want to take it because certain food should not be taken during the period of taking it. 9.4% did not want to take it because it tasted bitter. 6) In case of opinions on side effects of herb medicine, 40.8% of the respondents thinks that herb medicine is free from side effects, while 37.5% thinks that it causes side effects. There were significant difference in the opinions on side effects by sex, age, marital status, resident area, education level, occupation, and type of health insurance. 7) 60.7% of the respondents thinks the price of herb medicine is not resonable, while only 10.9% thinks it is resonable. 8) 45.2% of the respondents uses packs of decocted herbs although they think the packs of decocted herb are a little low effective because decocting herbs in home is bothersome. 45.2% uses packs of decocted herbs because they are convenient, being not related to the effect. 7.6% takes medicinal herbs after decocting them in a clay pot because they think the packs of decocted herbs have low effect. 51.9% does not know whether taking herb medicine in summer is effective or not because the effect is different according to their physical constitutions. 35.5% thinks that taking herb medicine is summer is effective because their physical stamina is weakened after sweated a lot, while 12.6% thinks that it is not effective because the effect of herb medicine disappears with sweat. 9) According to the level of satisfaction with Oriental medical care, the respondents marked $3.47{\pm}0.64$ points on the base of 5 points. It was significantly higher in the groups of 'male', 'the married, resident in a big city', 'highschool graduate', 'the unemployed', 'office clerk', 'growing up in a big city', 'insurant in region', and 'the middle class'. 10) According to the result of a regression analysis of factors influencing preference for herb medicine, the factors displayed significant difference by sex, age, education level, health status, and times of receiving Oriental medical care. As shown in the above results, the community residents satisfy with the effect of herb medicine. Therefore, the method of taking herb medicine without difficulty must be devised. The medicinal herbs in packages need to be included in health insurance coverage and resonable price of herb medicine must be set. Also, education program for community residents must be developed in order to provide right information in herb medicine. Therefore, related public authority, associations, and professionals must make efforts, forming organic cooperative system.

• The Journal of Internal Korean Medicine
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• v.17 no.1
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• pp.210-217
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• 1996

Farfarae Flos, a traditional herb medicine, has been used in Korea and China for many centuries as a treatment for respiratory disease. The purpose of the present study was to determine the effect of Farfarae Flos on histamine-induced tracheal smooth muscle contraction in rats. Guinea pigs(500g, female) were killed by CO2 exposure and a segment (8-10mm) of the thoracic trachea from each guinea pig was cut into equal segments and mounted 'in pairs' in a tissue bath. Contractile force was measured with force displacement transducers under 0.5g loading tension. The dose of histamine which evoked 50% of maximal response (ED50) was obtained from cumulative dose response curves for histamine (10-7-10-4M). Contractions evoked by histamine(ED50) were inhibited significantly by Farfarae Flos. The mean percent inhibition was 8.7% after 1.5mg/ml Farfarae Flos, and 33.5% (p<0.05) after 5.0mg/ml Farfarae Flos. Propranolol (10-7M) slightly but significantly attenuated the inhibitory effects of Farfarae Flos. Following treatment with propranolol, the mean percent inhibition caused by 5.0mg/ml Farfarae Flos. Indomethacin and methylene blue (10-7M) did not significantly alter the inhibitory effect of Farfarae Flos. These results indicate that Farfarae Flos can relax histamine-induced contraction of guinea pig tracheal smooth muscle, and that this inhibition involves, in part, symphathetic nerve system.

• Korean Journal of Medicinal Crop Science
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• v.21 no.2
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• pp.124-129
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• 2013

This study was conducted to investigate the residual contents of sulfur dioxide ($SO_2$) in commercial medicinal herbs in Korea in 2012. Among a total of 136 samples of 16 different kinds of herbs, 86 samples (15 Kinds) were domestic, and 50 samples (14 Kinds) were imported. Sulfur dioxide in the samples was measured by a modified Monier-Williams method. Of the 136 samples, 17 samples (12.5%, 6 Kinds) failed to meet the regulations for sulfur dioxide residues of KFDA in medicinal herbs. Among 17 unsuitable samples, 7 samples (8.1%, 3 Kinds) were domestic, and 10 samples (20.0%, 6 Kinds) were imported. The highest amount of sulfur dioxide residues was 3,167.94 mg/kg (Lycii Fructus) in the domestic samples. The detection frequency of sulfur dioxide by medicinal herb parts used, Rhizoma 25.7%, Flos 20.0%. Cortex 12.5%, Radix 15.3%, Fructus 7.6%, p-value 0.011. This results will be used as a basic data for the future legislation on the quality estimation and safety of medicinal herbs.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2003.04a
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• pp.65-66
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• 2003

Korean ginseng (Panax ginseng C. A. Meyer) is an representative medicinal herb. It is classified as an adaptogen, helping the body to adapt to stress, improving stamina and concentration, and providing a normalizing and restorative effect. However, cultivation and breeding of the plant is very difficult because it requires at least 4-year cultivation from seed germination to root harvest.(중략)

• The Korea Journal of Herbology
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• v.22 no.1
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• pp.13-24
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• 2007

Objectives : The plans such as Selaginellales, Equisetales and Psilotale have been used for treatment of diseases. Therefore, we examined their effects and distributions. Methods : We examined herbalogical books and research papers which published at home and abroad. Results : 1. There were totaled to 5 genera and 33 species in Selaginellales. Equisetales, Psilotales in Korea and among them medicinal plants are 4 genera, 21 species, about 64% in total. 2. Lycopodium genus is main kind enough that it has 13 species among 33species in the Selaginellales, Equisetales, Psilotales, of which medicinal plants are 10 species. 3. The herb is the main medicinal parts of medicinal plants in the Selaginellales, Equisetales, Psilotales which is used in 21 species. 4. On the bases of nature and flavor of medicinal plants in the Selaginellales, Equisetales. Psilotales, they were classified into neutral 15 species; bitter taste 15 in the order. 5. On the bases of meridian propism of medicinal plants in the Selaginellales, Equisetales. Psilotales, they were classified into liver meridian 11 species. 6. On the bases of the properties and principal curative action, they were classified into drugs for styptic 15 species, drugs for expel wind 14, drugs for drain damp 13 in the order. 7. It has been shown that one species in the Selaginellales, Equisetales, Psilotales is toxic. Conclusion : There were totaled to 5 genera and 33species in Farinales in Korea and among them medicinal plants are 4 genera, 21 species, About 63% in total.

• Advances in Traditional Medicine
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• v.9 no.1
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• pp.1-13
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• 2009

Medicinal herbs are significant source of synthetic and herbal drugs. In the commercial market, medicinal herbs are used as raw drugs, extracts or tinctures. Isolated active constituents are used for applied research. For the last few decades, phytochemistry (study of plants) has been making rapid progress and herbal products are becoming popular. According to Ayurveda, the ancient healing system of India, the classical texts of Ayurveda, Charaka Samhita and Sushruta Samhita were written around 1000 B.C. The Ayurvedic Materia Medica includes 600 medicinal plants along with therapeutics. Herbs like turmeric, fenugreek, ginger, garlic and holy basil are integral part of Ayurvedic formulations. The formulations incorporate single herb or more than two herbs (poly-herbal formulations). Medicinal herb contains multitude of chemical compounds like alkaloids, glycosides, saponins, resins, oleoresins, sesquiterpene, lactones and oils (essential and fixed). Today there is growing interest in chemical composition of plant based medicines. Several bioactive constituents have been isolated and studied for pharmacological activity. R. cordifolia is an important medicinal plant commonly used in the traditional and Ayurvedic system of medicine for treatment of different ailments. This review illustrates its major constituents, pharmacological actions substantiating the claims made about this plant in the traditional system of medicine and its clinical applications.

• CELLMED
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• v.5 no.2
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• pp.11.1-11.5
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• 2015

Traditional East Asian Medicine (TEAM) prescriptions typically consist of several herbs based on the assumption that the herbs operate synergistically and/or cooperate on several related pathways simultaneously. This is a general concept that is widely accepted in TEAM, but it has not been tested systematically. To check this assumption statistically, we have text mined traditional Korean medicine text the Inje-ji(仁濟志, Collections of benevolent savings), a text that contains more than 5000 herb-cocktail prescriptions. We created herb-pairing network based on herb-herb pairing specificity and performed a systematic network analysis. Herbs were shown to be used selectively with other herbs and not randomly. Moreover, herb pairs were more specifically associated with symptoms than were single herbs. Single herbs and combinations of herbs specifically used for diabetes mellitus were successfully identified. As conclusion, herb-pairings in TEAM are not randomly constructed; instead, each herb was selectively used with other herbs. In terms of statistical significance, herb pairs were more specifically associated with symptoms than were single herbs alone. Collectively, these results suggest that it may be important to understand the interactions among multiple ingredients contained in herb pairs rather than trying to identify a single compound to resolve symptoms.

• The Journal of Korean Obstetrics and Gynecology
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• v.25 no.2
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• pp.185-199
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• 2012

Objectives: This study aimed to review the effects and treatment of Korean, Oriental, Chinese medicine for premenstrual syndrome(PMS) as preceding research in order to further research the effective Korean Medicine treatment for PMS. Methods: Databases from Jan., 2002 through Feb., 2012 were searched through Pubmed for international journals; Korean studies information service system(KISS), National Discovery for Science Leaders(NDSL), Journal of Korean Acumoxa, J of Oriental Obstetrics and Gynecology, J of Meridian and Acupoint, and J of Korean Oriental Medicine for Korean journals were searched for national journals. The following search terms were used: acupuncture premenstrual syndrome, alternative medicine premenstrual syndrome, traditional Chinese medicine(TCM), premenstrual syndrome for Pubmed, premenstrual syndrome(in Korean and English) for the remaining search. Results: Twenty four studies were included in this review. Conclusions: Alternative medicinal intervention such as acupuncture and herb medicine may be effective treatment method in controlling premenstrual syndrome and premenstrual dysphoric disorder(PMDD).