• Title/Summary/Keyword: optical coherence tomography(OCT)

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Beam-scanning Imaging Needle for Endoscopic Optical Coherence Tomography

  • Yang, Woohyeok;Hwang, Junyoung;Moon, Sucbei
    • Current Optics and Photonics
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    • v.5 no.5
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    • pp.532-537
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    • 2021
  • We present a compact endoscopic probe in a needle form which has a fast beam-scanning capability for optical coherence tomography (OCT). In our study, a beam-scanning OCT imaging needle was fabricated with a 26G syringe needle (0.46 mm in outer diameter) and a thin OCT imaging probe based on the stepwise transitional core (STC) fiber. The imaging probe could freely rotate inside the needle for beam scans. Hence, OCT imaging could be performed without rotation or translation of the needle body. In our design, the structural integrity of the needle's steel tubing was preserved for mechanical robustness. Probing the optical signal was performed through the needle's own window formed at the end. For hand-held operation of our imaging needle, a light and compact scanner module (130 g and 45 × 53 × 60 mm3) was devised. Connected to the imaging needle, it could provide rotational actuation driven by a galvanometer. Because of its finite actuation range, our scanner module did not need a fiber rotary joint which might add undesirable complexity. The beam scan speed was 20 Hz and supported 20 frames per second at the maximum for endoscopic OCT imaging.

Microscopic Imaging of Articular Cartilage using Polarization-Sensitive Optical Coherence Tomography

  • Lee Sang-Won;Oh Jung-Taek;Kim Beop-Min
    • Journal of Biomedical Engineering Research
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    • v.26 no.1
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    • pp.37-42
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    • 2005
  • We construct and test the polarization-sensitive optical coherence tomography (PS-OCT) system for imaging porcine and human articular cartilages. PS-OCT is a new imaging technology that provides information regarding not only the tissue structures but tissue components that show birefringence such as collagen. In this study, we measure the cartilage thickness of the porcine joint and the phase retardation due to collagen birefringence. Also, we demonstrate that changes of the collagen fiber orientation could be detected by the PS-OCT system. Finally, differences between normal and damaged human articular cartilage are observed using the PS-OCT system, which is then compared with the regular histology pictures. As a result, the PS-OCT system is proven to be effective for diagnosis of the pathology related to the cartilage. In the future, this technology may be used for discrimination of the collagen types. When combined with endoscope technologies, the PS-OCT images may become a useful tool for in vivo tissue testing.

Investigation of Spot Marking in Multilayer Thin Films using OCT (OCT에 의한 다층 박막의 Spot Marking 분석)

  • Shin Yongjin;Kim Hyunjin;Kim Youngseop;Park Sohee
    • Laser Solutions
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    • v.7 no.2
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    • pp.11-18
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    • 2004
  • We propose a novel application of optical coherence tomography (OCT) to monitor pit formation in laser irradiated optical storage materials. A multilayer optical storage recordable compact disk, is composed of multiple layers, each of different structure. Disks were irradiated with aQ-Switched Nd:YAG laser with an energy of 373 mJ. Post-irradiated disks were evaluated by OCT and those images were compared with optical microscopy. Our results indicate that OCT is a useful instrument to investigate pit formation in multilayer optical storage disks and might also provide information to optimize optical memory technology.

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Implementation of Cost-effective Common Path Spectral Domain Free-hand Scanning OCT System

  • Shoujing Guo;Xuan Liu;Jin U. Kang
    • Current Optics and Photonics
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    • v.7 no.2
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    • pp.176-182
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    • 2023
  • Optical coherence tomography (OCT) is being developed to guide various ophthalmic surgical procedures. However, the high cost of the intraoperative OCT system limits its availability mostly to the largest hospitals and healthcare systems. In this paper, we present a design and evaluation of a low-cost intraoperative common-path free-hand scanning OCT system. The lensed fiber imaging probe is designed and fabricated for intraocular use and the free-hand scanning algorithm that could operate at a low scanning speed was developed. Since the system operates at low frequencies, the cost of the overall system is significantly lower than other commercial intraoperative OCT systems. The assembled system is characterized and shows that it meets the design specifications. The handheld OCT imaging probe is tested on multilayer tape phantom and ex-vivo porcine eyes. The results show that the system could be used as an intraoperative intraocular OCT imaging device.

Scientific and Engineering Applications of Full-field Swept-source Optical Coherence Tomography

  • Mehta, Dalip Singh;Anna, Tulsi;Shakher, Chandra
    • Journal of the Optical Society of Korea
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    • v.13 no.3
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    • pp.341-348
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    • 2009
  • We report the development of full-field swept-source optical coherence tomography (SS-OCT) in the wavelength range of 815-870 nm using a unique combination of super-luminescent diode (SLD) as broad-band light source and acousto-optic tunable filter (AOTF) as a frequency-scanning device. Some new applications of full-field SS-OCT in forensic sciences and engineering materials have been demonstrated. Results of simultaneous topography and tomography of latent fingerprints, silicon microelectronic circuits and composite materials are presented. The main advantages of the present system are completely non-mechanical scanning, wide-field, compact and low-cost.

Endoscopic Imaging and Fabrication of Micro-endoscope Catheter in Time-domain Optical Coherence Tomography (시간영역 광 간섭 단층촬영 시스템의 소형 엔도스코프 제작 및 영상구현)

  • Kim, Young-Kwan;Lee, Sung-Hun;Kim, Yong-Pyung
    • Korean Journal of Optics and Photonics
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    • v.21 no.5
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    • pp.206-213
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    • 2010
  • We fabricated and characterized a compact endoscopic catheter for optical coherence tomography. The optical delay line (ODL), composed of a cylindrical piezoelectric transducer (PZT) and an optical fiber, was operated with a 1 kHz sinusoidal driving wave in the time-domain. When the ODL was driven with a sinusoidal wave function, the axial scanning speed was 6 m/s and the axial acquisition rate was 2000 line/s at a depth of about 3 mm. Endoscopic OCT images of a human finger and earhole were successfully obtained with an image rate of ten frames per second.

Comparisons of the diagnostic accuracies of optical coherence tomography, micro-computed tomography, and histology in periodontal disease: an ex vivo study

  • Park, Jin-Young;Chung, Jung-Ho;Lee, Jung-Seok;Kim, Hee-Jin;Choi, Seong-Ho;Jung, Ui-Won
    • Journal of Periodontal and Implant Science
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    • v.47 no.1
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    • pp.30-40
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    • 2017
  • Purpose: Optical coherence tomography (OCT) is a noninvasive diagnostic technique that may be useful for both qualitative and quantitative analyses of the periodontium. Micro-computed tomography (micro-CT) is another noninvasive imaging technique capable of providing submicron spatial resolution. The purpose of this study was to present periodontal images obtained using ex vivo dental OCT and to compare OCT images with micro-CT images and histologic sections. Methods: Images of ex vivo canine periodontal structures were obtained using OCT. Biologic depth measurements made using OCT were compared to measurements made on histologic sections prepared from the same sites. Visual comparisons were made among OCT, micro-CT, and histologic sections to evaluate whether anatomical details were accurately revealed by OCT. Results: The periodontal tissue contour, gingival sulcus, and the presence of supragingival and subgingival calculus could be visualized using OCT. OCT was able to depict the surface topography of the dentogingival complex with higher resolution than micro-CT, but the imaging depth was typically limited to 1.2-1.5 mm. Biologic depth measurements made using OCT were a mean of 0.51 mm shallower than the histologic measurements. Conclusions: Dental OCT as used in this study was able to generate high-resolution, cross-sectional images of the superficial portions of periodontal structures. Improvements in imaging depth and the development of an intraoral sensor are likely to make OCT a useful technique for periodontal applications.

Depth-resolved Stokes parameters of light backscattered from turbid media with polarization-sensitive optical coherence tomography system and successive phase-shifting algorithm (위상천이원리 와 PS-OCT시스템을 적용한 역산란광의 매질 깊이별 스톡스변수 추출)

  • Oh, Jung-Taek;Kim, Seung-Woo
    • Proceedings of the Optical Society of Korea Conference
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    • 2003.02a
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    • pp.286-287
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    • 2003
  • Polarization-sensitive optical coherence tomography (PS-OCT) was developed to image highly scattering tissues with accounting for polarization effects in the sample. These polarization-sensitive images can provide additional information on the structure of the tissue because of a polarization state of the light is changed at its interaction with biological tissues. The scattering and birefringence are two phenomena, which change the polarization state of light passing through medium. (omitted)

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Speckle Reduction Method in Wavelet Domain for OCT Image Enhancement (OCT 영상 개선을 위한 웨이블릿 영역에서의 Speckle 저감 방법)

  • Lee Chang-Su;Na Ji-Hoon;Lee Byeong-Ha;Chang Ju-Wan
    • Journal of Institute of Control, Robotics and Systems
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    • v.12 no.4
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    • pp.364-370
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    • 2006
  • Optical coherence tomography (OCT) is high resolution medical imaging system which is obtaining image inside biological objects with non-destructive method. OCT system is based on Michelson interferometer with a reciprocating mirror in the reference arm and a biological object in the sample arm. The obtained OCT image suffers from a granular or mottled image, called speckle. Speckle is caused by random interferences between reflected coherence waves. In this paper, we propose effective speckle reduction method that uses wavelet transform. With wavelet domain image, sub-windowing and thresholding are performed. Finally, speckle reduction experiments for Misgurnus mizolepis skin and rat eye images are shown.

Compensations of Polarization Mode Dispersion and Thermal Drift in Optical Coherence Tomography with PZT Optical Delay Lines (광간섭 단층촬영(OCT)용 PZT 광경로 지연기에서의 편광모드 분산 및 열요동 보상)

  • Kim, Young-Kwan;Park, Sung-Jin;Kim, Yong-Pyung
    • Korean Journal of Optics and Photonics
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    • v.16 no.6
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    • pp.547-552
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    • 2005
  • We have fabricated and characterized optical delay lines for optical coherence tomography, which is composed of cylindrical PZT(piezoelectric transducer) and single mode optical fiber. The polarization mode dispersion from the optical delay lines was compensated by the polarization controllers. By applying the duplex optical delay line, we minimized the thermal drift due to optical delay lines and obtained the scan range of 2 times that of a single optical delay line. The OCT system showed resolution of $18.6\pm0.5{\mu}m$, scanning range of 1.68mm, and scanning speed of 360.4mm/s.