• Proceedings of the Korean Vacuum Society Conference
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• 2016.02a
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• pp.144.2-144.2
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• 2016

Diamond-like carbon (DLC) coatings have been widely applied to the mechanical components, cutting tools due to properties of high hardness and wear resistance. Among them, hydrogenated amorphous carbon (a-C:H) coatings are well-known for their low friction properties, stable production of thin and thick film, they were reported to be easily worn away under high temperature. Non-hydrogenated tetrahedral amorphous carbon (ta-C) is an ideal for industrial applicability due to good thermal stability from high $sp^3$-bonding fraction ranging from 70 to 80 %. However, the large compressive stress of ta-C coating limits to apply thick ta-C coating. In this study, the thick ta-C coating was deposited onto Inconel alloy disk by the FCVA technique. The thickness of the ta-C coating was about $3.5{\mu}m$. The tribological behaviors of ta-C coated disks sliding against $Si_3N_4$ balls were examined under elevated temperature divided into 23, 100, 200 and $300^{\circ}C$. The range of temperature was setting up until peel off observed. The experimental results showed that the friction coefficient was decreased from 0.14 to 0.05 with increasing temperature up to $200^{\circ}C$. At $300^{\circ}C$, the friction coefficient was dramatically increased over 5,000 cycles and then delaminated. These phenomenon was summarized two kinds of reasons: (1) Thermal degradation and (2) graphitization of ta-C coating. At first, the reason of thermal degradation was demonstrated by wear rate calculation. The wear rate of ta-C coatings showed an increasing trend with elevated temperature. For investigation of relationship between hardness and graphitization, thick ta-C coatings(2, 3 and $5{\mu}m$) were additionally deposited. As the thickness of ta-C coating was increased, hardness decreased from 58 to 49 GPa, which means that graphitization was accelerated. Therefore, now we are trying to increase $sp^3$ fraction of ta-C coating and control the coating parameters for thermal stability of thick ta-C at high temperatures.

• Tuberculosis and Respiratory Diseases
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• v.72 no.3
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• pp.293-301
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• 2012

Background: Ventilator-associated pneumonia (VAP) requires prompt and appropriate treatment. Since methicillin-resistant Staphylococcus aureus (MRSA) is a frequent pathogen in VAP, rapid identification of it, is pivotal. Our aim was to evaluate the utility of quantitative polymerase chain reaction (qPCR) as a useful method for etiologic diagnoses of MRSA pneumonia. Methods: We performed qPCR for mecA, S. aureus-specific femA-SA, and S. epidermidis-specific femA-SE genes from bronchoalveolar lavage or bronchial washing samples obtained from clinically-suspected VAP. Molecular identification of MRSA was based on the presence of the mecA and femA-SA gene, with the absence of the femA-SE gene. To compensate for the experimental and clinical conditions, we spiked an internal control in the course of DNA extraction. We estimated number of colony-forming units per mL (CFU/mL) of MRSA samples through a standard curve of a serially-diluted reference MRSA strain. We compared the threshold cycle (Ct) value with the microbiologic results of MRSA. Results: We obtained the mecA gene standard curve, which showed the detection limit of the mecA gene to be 100 fg, which corresponds to a copy number of 30. We chose cut-off Ct values of 27.94 (equivalent to $1{\times}10^4$ CFU/mL) and 21.78 (equivalent to $1{\times}10^5$ CFU/mL). The sensitivity and specificity of our assay were 88.9% and 88.9% respectively, when compared with quantitative cultures. Conclusion: Our results were valuable for diagnosing and identifying pathogens involved in VAP. We believe our modified qPCR is an appropriate tool for the rapid diagnosis of clinical pathogens regarding patients in the intensive care unit.

• Journal of Preventive Medicine and Public Health
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• v.36 no.3
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• pp.248-254
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• 2003

Objective : This study was conducted in order to investigate predictors of smoking cessation in outpatients. Method : Subjects were 40f adult smoking patients who saw their doctors in the outpatient setting at a university hospital, regardless of their willingness of otherwise in smoking cessation. Physicians delivered a brief, stop smoking prompt to all patients who smoked one or more cigarettes a day. Then they referred to on-site counselors who provided a brief, nurse assisted intervention with a survey to a randomly assigned intervention group (200 smoking patients), whom the counselors telephoned later to prevent relapse or promote the motivation to quit, or gave only a survey to a control group (201 smoking patients). After at least 5 months, self-reported current smoking cessation was confirmed later using cut-off values of 7 ppm or less in expired alveolar air after breath holding portable CO analyzer. Results : After 5 months, subjects in the intervention group were 1.56 times (95% C.I. 0.89-2.73) more likely to quit smoking than those in the non-intervention group (14.0% vs. 9.0%). Willingness to quit smoking in a month, scheduled admission in a month, self efficacy score and FTND (Fagerstrom Test for Nicotine Dependence) score were all significantly related with smoking cessation. In stepwise multiple logistic regression, previous attempts to quit smoking were significant instead of self efficacy score. In the intervention group who had willingness to quit smoking in a month (132 smoking patients), FTND score, whether quit date was today, and whether quit promise paper was submitting were all significantly related with smoking cessation. In stepwise multiple logistic regression, scheduled admission in a month and whether quit date was today were significant predictor variables, Smoking cessation treatment should be tailored to individual smoking patients considering these predictors.

• Journal of the Korean Society of School Health
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• v.12 no.1
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• pp.97-107
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• 1999

The purpose of the study was to ascertain the trends of future circumstances in primary education along with population change. These trends, which are subject to change in population and structure, have a great impact on the size and characteristics of primary school-aged children. Accordingly, it is imperative for the government to plan for future conditions involving primary education. The major findings of the study were as follows: 1. In the long-term primary school children aged 6-11, which accounted for 17.7% of the total population in 1970, will decline to 8.6% by the year 2000, 6.9% in 2020 and 6.4% in 2030. This drastic reduction in fertility rate is a direct result of pressure by the government to control population. 2. In 1996, the total number of classes in primary schools rose to 106,594. In the future, these numbers will actually decline. By 2003 the total number of classes will peak at 142,605, but until then drop off to 112,288 by 2030-a decrease of over 6,000. 3. The actual number of primary schools in 1997 totaled 5,721. This figure will reach its highest peak, 5,942, in 2003, but it is expected decrease later after declining by 1,263, it will bottom out at 4,679 in 2003. 4. The number of teachers at primary schools increased from 101,095 in 1970, 119, 064 in 1980, 136,800 in 1990 to 138,369 in 1995. Accordingly this means that the ratio of students to teaching staff changed for the better. By the year 2005, if teachers of specialty subjects (music, art, English, physical education) are assigned to every primary school with over 18 classrooms and the number of students per class is 30, it should improve educational surroundings. This is because it is expected that the population of primary school children will continue to grow until 2003 and then decrease. Thus, there is a need to maintain the number of primary school teachers between the years 2003 and 2030 so that the ratio of students to teachers will be reduced to 1/20.25. In considering factors related to migration which influence conditions of education, it is evident that changes have already begun. In the suburbs of Seoul, population shifts are causing overcrowding in classrooms. The government believes it would be inefficient to invest in education because fluctuating migration figures make it impossible. Accordingly, we have to be concerned about stabilizing the population throughout the entire country.

• Journal of Korean Society of Environmental Engineers
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• v.28 no.1
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• pp.104-110
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• 2006

Growth in population and urbanization has progressively increased the loadings of pollutants from non-point sources as well as point sources. Accordingly, release of contaminants from non-point sources, released with surface runoff of rainwater, is influenced by atmospheric phenomena, geology, and topography. This makes the control of non-point source difficult. Therefore, this study intends to reveal the characteristics of runoff and particle size distribution to observe the fundamental characteristics of runoff. Experiments were carried out at inner road of research center. Average concentration of runoff ranged from 26.8 to 126.4 mg/L for SS and $COD_{Cr}\;15.3{\sim}117.7mg/L,\;TN\;0.07{\sim}5.16mg/L,\;TP\;0.06{\sim}0.49mg/L$ and heavy metals $0.00{\sim}0.29mg/L$. First flush, indicated wash off of pollutant at first rain, was observed for all types of pollutants. Most pollutants revealed a very close correlation with SS ($R^2=0.93{\sim}0.99$). After analyzing characteristics of particle, particle was finer than that from previously examined data.

• The Journal of the Korea Contents Association
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• v.16 no.6
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• pp.225-235
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• 2016

This study aims at developing Reminiscence Function Scale-Short Form(RFS-S) and verifying it as a supplemental diagnosis instrument to judge differences between normal and mild cognitive impairment and useful measure to rate effects of reminiscence therapy in the clinical field through internal consistency reliability and criterion validity. The study also aims at figuring out factors affection reminiscence function by figuring out demographic features of RFS-S. The research subjects were the control group of 60 normal people and experimental group of 58 people with mild cognitive impairment and both groups were over 65 years old. For internal consistency reliability(Cronbach's alpha) between questions was reliable with 0.63. Convergent validities of RFS-S with SRT and CDR-SB were 0.20(p<.05) and -0.25(p<.001), respectively, as both showed significant correlations. As a result of criterion validity to analyze AUROC, it was 0.68(p<.001) and less accurate. Its optimal cut-off points were 17 and sensitivity according to them was 0.59, and specificity was 0.72, respectively. However, reminiscence function according to demographic variables did not show any significant differences. Therefore, it is expected that RFS-S will be used as a supplemental diagnosis instrument with higher reliability and validity for discerning differences between normal and mild cognitive impairment and as a useful one to verify effects of reminiscence therapy.

• Korea journal of population studies
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• v.22 no.2
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• pp.197-220
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• 1999

Family, Self or State as a Desired Source of Support for the Elderly As Korean society has undergone rapid socioeconomic transformation and reached the final stage of its demographic transition, the central emphasis of population policies in Korea has shifted from fertility and population control to aging issues. Recently, it has been advocated that the Korean government should provide more intensive public services to supplement self-care and family caregiving, heightening the need to know more about the norms and expectations of old-age support and how they will change. Using the Survey of the Living Status of the Korean Elderly in 1994, this study investigates the extent to which the Korean elderly themselves view family, self, or the state as desired sources of support. The multinomial log it model analysis reveals that the elderly without a son are less likely to emphasize the traditional view of family, while economically and physically better off elderly are more likely to favor the view of self-support. However, the idea that the emphasis on the 'state responsibility' may be found among those elderly who are in need of financial help and in poor health is not supported. The implications and suggestions for further research are discussed.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.2053-2058
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• 2013

Background: Formation of new blood vessels is necessary for the development and spread of neoplasms more than 1 mm3 in volume, angiogenesis being responsible for formation of new from pre-existing blood vessels. Vascular endothelial growth factor (VEGF) is pivotal and the best studied angiogenic factor in all human cancers. Therefore we designed this study to investigate the role of VEGF-A and VEGF-C in prostate cancer in comparison with BPH controls in a north Indian population. Methods: In this case-control study a total of 100 subjects were included on the basis of confirmed histopathological reports, out of which 50 were prostate cancer patients and the other 50 were BPH patients with PSA levels >2 ng/ml and abnormal digital rectal examination (DRE) findings during September 2009 to August 2011 from the Department of Urology, KGMU, Lucknow, India. Plasma levels of VEGF were determined using quantitative immunoassay (ELISA-enzyme linked immunosorbent assay). Statistical analysis was carried out using SPSS 15.0 version. Results: The mean age of prostate cancer ($67.6{\pm}5.72$) patients was significantly higher (p=0.005) than BPH ($63.6{\pm}7.92$) patients. Expression of VEGF-A was not significantly higher in disease stage C1 than D1 or D2 and A or B (p=0.13) while the level of VEGF-A was significantly higher (p=0.04) in prostate cancer as compared to BPH subjects (PCa=13.0 pg/ml, BPH=6.8 pg/ml). Levels of VEGF-C were similar in both groups (PCa=832.6 pg/ml, BPH=823.7 pg/ml). In ROC curve, the area under curve (AUC) was 0.70 (95%CI: 0.60-0.80) and the cut-off value for which a higher proportion of patients was correctly classified (20%) was 26.0 pg/mL. Conclusion: Although VEGF-A is increased in cancer prostate patients a statistically significant correlation could not be established in this study. VEGF-C was not found to be a useful biomarker.

• Asia pacific journal of information systems
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• v.19 no.1
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• pp.63-82
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• 2009

Virtual community is a social aggregation to attain some goals in an IT-supported virtual space (Lee et al., 2002). As lots of virtual communities generate robust and reliable outputs with low control and low incentive, previous researchers was interested in the questions, "why do they participate?" or "how are they controlled?". But. as Katz (1964) said, the most important part of the high-performing organization is the behaviors of members in the organization. Therefore, this research is to examine the relationship between the performance and the behaviors of participants in the virtual community. First, we propose 6 types of behaviors related to high performance in the virtual community: 'Continuous Attendance', 'Complying with the organizational value, policies, and regulations', 'Protection', 'Suggestion for the improving', 'Self-training', and 'Favorable behavior'. The six types of behaviors are extracted from the framework of Katz (1964) and Brief and Motowidlo (1986). The reason why each behavior is positively related with high-performance is that those who continuously attend have more responsibility than temporary participants do; complying with the rules of a virtual community means that they may make more reliable outcome; 'Protection' is one of the prosocial-behaviors and those who protect the community may concern the benefit of the virtual community when they participate: those who suggest some ideas for improvement may contribute to the virtual community; 'Self-training' behavior means that participants really want to have high quality in their contribution: those who have 'Favorable attitude' consider other members in the virtual community when they participate. Then, we perform an empirical analysis with the survey from participants in the Knowledge service of Naver.com, to show those behaviors are associated with the high-performance. To make the measurement for the six behaviors, we use CVR (content validity ratio) method (Lawshe, 1975), interviewing 12 experts. The dependent variable, performance of participation, is measured by 'ratio of selected answer' given by the Naver.com. We use email survey. We sent 1200 emails to randomly selected participants in the knowledge service and received 282 responses. The results of our empirical analysis show that 4('Continuous Attendance', 'Suggestion for the improving', 'Self-training', 'Favorable attitude') are positively related to the performance, but 2('Complying with the organizational value, policies, and regulations' and 'Protection') are not significant. In line with Fitzgerald (2006), we expect that participants in the virtual community may behave similarly to employees in the off-line firms for the high performance. But 2 behaviors have different results. The reason that the 'Complying with the organizational value' behavior is not sufficiently related to performance is that the motivation of participants is more related to intrinsic pleasure or altruism than external reward. Also, the 'Protection' behavior has no significant relationship with performance, which means that the high-performing participants have little concern about the problems in the community.

• Korean Journal of Food Science and Technology
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• v.28 no.4
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• pp.684-688
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• 1996

In order to search for antithrombotic peptides from soybean paste, the inhibitory activity of water extract of soybean paste and its peptide fractions on ADP-induced aggregation of washed platelets was assayed. Soybean paste extract treated with ultrafiltration (M.W. cut off, 3,000 daltons) was found to have inhibitory activity of 90% at the dose of $96\;{\mu}g/ml$ by the method of turbidometric aggregometer. Soybean paste extract was fractionated to 19 fractions (No. B-18) by Dowex 50W X-2 ion exchange column chromatography and activity test was performed by the microplate method. All of the fractions had antithrombotic activity $(IC_{50},\;101,000\;{\mu}g/ml)$, and most fractions had higher activity than positive control, RGDS $(IC_{50}.\;205\;{\mu}g/ml)$. Especially, basic fractions No.16-18 showed higher activity than soybean paste extract $(IC_{50},\;30\;{\mu}g/ml)$. The fraction No.16 with the highest activity $(IC_{50},\;10\;{\mu}g/ml)$ was purified and analysed for amino acid composition. The results showed that histidine, arginine, and alanine were major residues in the peptide part of the fraction.