• Title/Summary/Keyword: on-line reviews

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NEW ANTIDEPRESSANTS IN CHILD AND ADOLESCENT PSYCHIATRY (소아청소년정신과영역의 새로운 항우울제)

  • Lee, Soo-Jung
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.14 no.1
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    • pp.12-25
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    • 2003
  • Objectives:As increasing number of new antidepressants have been being introduced in clinical practice, pharmacological understanding has been broadened. These changes mandate new information and theories to be incorporated into the treatment process of children with depressive disorders. In light of newly coming knowledge, this review intended to recapitulate the characteristics of new antidepressants and to consider the pivotal issues to develope guidelines for the treatment of depression in childhood and adolescence. Methods:Searching the Pub-Med online database for the articles with the key words of 'new', 'antidepressants' and 'children' ninety-seven headings of review articles were obtained. The author selected the articles of pertinent subjects in terms of either treatment guideline or psychopharmacology of new antidepressants. When required, articles about the clinical effectiveness of individual antidepressants were separatedly searched. In addition, the safety information of new antidepressants was acquired by browsing the official sites of the United States Food and Drugs Administration and Department of Health and Human Services. Results:1) For the clinical course, treatment phase, and treatment outcome, the reviews or treatment guidelines adopted the information from adult treatment guidelines. 2) Systematic and critical reviews unambiguously concluded that selective serotonin reuptake inhibitors(SSRIs) excelled tricyclic antidepressants( TCAs) for both efficacy and side effect profiles, and were recommend for the first-line choice for the treatment of children with depressive disorders. 3) New antidepressants generally lacked treatment experiences and randomized controlled clinical trials. 4) SSRIs and other new antidepressants, when used together, might result in pharmacokinetic and/or pharmacodynamic drug-to-drug interaction. 5) The difference of the clinical effectiveness of antidepressants between children and adults should be addressed from developmental aspects, which required further evidence. Conclusion:Treatment guidelines for the pharmacological treatment of childhood and adolescence depression could be constructed on the basis of clinical trial findings and practical experiences. Treatment guidelines are to best serve as the frame of reference for a clinician to make reasonable decisions for a particular therapeutic situation. In order to fulfill this role, guidelines should be updated as soon as new research data become available.

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Equivalent Design Parameter Determination for Effective Numerical Modeling of Pre-reinforced Zones in Tunnel (터널 사전보강 영역의 효과적 수치해석을 위한 등가 물성치 결정 기법)

  • Song, Ki-Il;Cho, Gye-Chun
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.8 no.2
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    • pp.151-163
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    • 2006
  • Although various methods for effective modeling of pre-reinforced zones have been suggested for numerical analysis of large section tunnels, tunnel designers refer to empirical cases and literature reviews rather than engineering methods because ones who use commercial programs are unfamiliar with a macro-scale approach in general. Therefore, this paper suggests a simple micro-scale approach combined with the macro-scale approach to determine equivalent design parameters for effective numerical modeling of pre-reinforced zones in tunnel. This new approach is to determine the equivalent stiffness of pre-reinforced zones with combination of ground, bulb, and steel in series or/and parallel. For verification, 3-D numerical results from the suggested approach are compared with those of a realistic model. The comparison suggests that two cases make best approximation to a realistic solution: One is related to the series-parallel stiffness system (hereafter SPSS) in which bulb and steel are coupled in parallel and then connected to the ground in series, and the other is the series stiffness system (hereafter SSS) in which only bulb and steel are coupled in series. The SPSS is recommended for stiffness calculation of pre-reinforced zones because the SSS is inconvenient and time-consuming. The SPSS provides slightly bigger vertical displacement at tunnel crown in weathered rock than other cases and give almost identical results to a realistic model for horizontal displacement at tunnel spring line and ground surface settlement. Displacement trends on weathered rock and weathered soil are similar. The SPSS which is suggested in this paper represents the behavior mechanism of pre-reinforced area effectively.

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Elemental Analysis by Neutron Induced Nuclear Reaction - Prompt Gamma Neutron Activation Analysis for Chemical Measurement - (중성자 핵반응을 이용한 원소 검출기술 - 즉발감마선 중성자 방사화분석법을 이용한 검출기술 -)

  • Song, Byung Chul;Park, Yong Joon;Jee, Kwang Yong
    • Analytical Science and Technology
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    • v.16 no.5
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    • pp.1041-1051
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    • 2003
  • Neutron induced prompt gamma activation analysis (PGAA) offers a nondestructive, sensitive and relatively rapid method for the determination of trace and major elements and is proven to be convenient for online analysis of minerals, metals, coal, cement, petrochemical, coating, paper as well as many other materials and products. The technique has found many uses in medicine, industry, research, security and the detection of contraband items. This report reviews the present status and future trends of the PGAA techniques. Requirements for the system are neutron source, high resolution HPGe detectors with a high-voltage power supply, an amplifier, analog-to-digital converter, and a multichannel analyzer for the detection and measurement of prompt ${\gamma}$-ray emit form the neutron capture elements. Introducing a ${\gamma}$-${\gamma}$ coincidence system also improves the quality of the ${\gamma}$-ray spectrum by suppressing the background created from the Compton scattering of high energy prompt ${\gamma}$-rays. A PGAA system using a $^{252}Cf$ neutron source is currently under construction for the on-line measurement of several elements in aqueous samples at KAERI. The system can be applied for the detection of chemical weapons and explosives as well as various narcotics.

Analysis on Students' Abilities of Proof in Middle School (중학교 학생의 증명 능력 분석)

  • 서동엽
    • Journal of Educational Research in Mathematics
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    • v.9 no.1
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    • pp.183-203
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    • 1999
  • In this study, we analysed the constituents of proof and examined into the reasons why the students have trouble in learning the proof, and proposed directions for improving the teaming and teaching of proof. Through the reviews of the related literatures and the analyses of textbooks, the constituents of proof in the level of middle grades in our country are divided into two major categories 'Constituents related to the construction of reasoning' and 'Constituents related to the meaning of proof. 'The former includes the inference rules(simplification, conjunction, modus ponens, and hypothetical syllogism), symbolization, distinguishing between definition and property, use of the appropriate diagrams, application of the basic principles, variety and completeness in checking, reading and using the basic components of geometric figures to prove, translating symbols into literary compositions, disproof using counter example, and proof of equations. The latter includes the inferences, implication, separation of assumption and conclusion, distinguishing implication from equivalence, a theorem has no exceptions, necessity for proof of obvious propositions, and generality of proof. The results from three types of examinations; analysis of the textbooks, interview, writing test, are summarized as following. The hypothetical syllogism that builds the main structure of proofs is not taught in middle grades explicitly, so students have more difficulty in understanding other types of syllogisms than the AAA type of categorical syllogisms. Most of students do not distinguish definition from property well, so they find difficulty in symbolizing, separating assumption from conclusion, or use of the appropriate diagrams. The basic symbols and principles are taught in the first year of the middle school and students use them in proving theorems after about one year. That could be a cause that the students do not allow the exact names of the principles and can not apply correct principles. Textbooks do not describe clearly about counter example, but they contain some problems to solve only by using counter examples. Students have thought that one counter example is sufficient to disprove a false proposition, but in fact, they do not prefer to use it. Textbooks contain some problems to prove equations, A=B. Proving those equations, however, students do not perceive that writing equation A=B, the conclusion of the proof, in the first line and deforming the both sides of it are incorrect. Furthermore, students prefer it to developing A to B. Most of constituents related to the meaning of proof are mentioned very simply or never in textbooks, so many students do not know them. Especially, they accept the result of experiments or measurements as proof and prefer them to logical proof stated in textbooks.

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Reviews of Literature on Dental Plaque Control and Oral Hygiene Education in Korea (치면세균막관리와 구강보건교육에 관한 국내문헌고찰)

  • Choi, Moon-Sil;Kim, Dong-Kie
    • Journal of dental hygiene science
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    • v.17 no.2
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    • pp.87-98
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    • 2017
  • The purpose of this study was to understand the effectiveness of oral health education (OHE) or oral hygiene instruction (OHI) involving professional plaque control/removal, as compared to conventional plaque control/removal. By means of a systematic review of the literature, in the review of literature by using systematic method, Korean articles of plaque control including OHE or OHI, were studied in order to analyze and conclude the literature to enhance oral health. We found that self and professional plaque control/removal, in addition to tooth brushing instructions, decreased incidence and prevalence of loss of teeth. Taken together, professional mechanical plaque removals were most effective 4~5 visits every 1~2 weeks. Use of disclosing agent was more effective than oral education or model education. In line with oral hygiene education, professional brushing, oral prophylaxis, scaling and root planing, it was advisable to repeat the training according to the characteristics of the patient. Routine OHE or OHI would be help to increase to oral health. For a quality of life related oral health, reliability and validity of data are needed to develop and its data should be applied to dental health insurance policy.

Cryotherapy versus radiofrequency ablation in the treatment of dysplastic Barrett's esophagus with or without early esophageal neoplasia: a systematic review and meta-analysis

  • Igor Logetto Caetite Gomes;Diogo Turiani Hourneaux de Moura;Igor Braga Ribeiro;Sergio Barbosa Marques;Alexandre de Sousa Carlos;Beanie Conceicao Medeiros Nunes;Bruno Salomao Hirsch;Guilherme Henrique Peixoto de Oliveira;Roberto Paolo Trasolini;Wanderley Marques Bernardo;Eduardo Guimaraes Hourneaux de Moura
    • Clinical Endoscopy
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    • v.57 no.2
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    • pp.181-190
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    • 2024
  • Background/Aims: Radiofrequency ablation (RFA) is the first-line therapy for dysplastic Barrett's esophagus (BE). Therefore, cryotherapy has emerged as an alternative treatment option. This study aimed to compare the efficacies of these two techniques based on the rates of complete eradication of intestinal metaplasia (CE-IM) and dysplasia (CE-D). Adverse events and recurrence have also been reported. Methods: An electronic search was conducted using the Medline (PubMed), Embase, LILACS, and Google Scholar databases until December 2022. Studies were included comparing cryotherapy and RFA for treating dysplastic BE with or without early esophageal neoplasia. This study was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Results: Three retrospective cohort studies involving 627 patients were included. Of these, 399 patients underwent RFA, and 228 were treated with cryotherapy. There was no difference in CE-IM (risk difference [RD], -0.03; 95% confidence interval [CI], -0.25 to 0.19; p=0.78; I2=86%) as well as in CE-D (RD, -0.03; 95% CI, -0.15 to 0.09; p=0.64; I2=70%) between the groups. The absolute number of adverse events was low, and there was no difference in the recurrence rate. Conclusions: Cryotherapy and RFA were equally effective in treating dysplastic BE, with or without early esophageal neoplasia.

Story-based Information Retrieval (스토리 기반의 정보 검색 연구)

  • You, Eun-Soon;Park, Seung-Bo
    • Journal of Intelligence and Information Systems
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    • v.19 no.4
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    • pp.81-96
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    • 2013
  • Video information retrieval has become a very important issue because of the explosive increase in video data from Web content development. Meanwhile, content-based video analysis using visual features has been the main source for video information retrieval and browsing. Content in video can be represented with content-based analysis techniques, which can extract various features from audio-visual data such as frames, shots, colors, texture, or shape. Moreover, similarity between videos can be measured through content-based analysis. However, a movie that is one of typical types of video data is organized by story as well as audio-visual data. This causes a semantic gap between significant information recognized by people and information resulting from content-based analysis, when content-based video analysis using only audio-visual data of low level is applied to information retrieval of movie. The reason for this semantic gap is that the story line for a movie is high level information, with relationships in the content that changes as the movie progresses. Information retrieval related to the story line of a movie cannot be executed by only content-based analysis techniques. A formal model is needed, which can determine relationships among movie contents, or track meaning changes, in order to accurately retrieve the story information. Recently, story-based video analysis techniques have emerged using a social network concept for story information retrieval. These approaches represent a story by using the relationships between characters in a movie, but these approaches have problems. First, they do not express dynamic changes in relationships between characters according to story development. Second, they miss profound information, such as emotions indicating the identities and psychological states of the characters. Emotion is essential to understanding a character's motivation, conflict, and resolution. Third, they do not take account of events and background that contribute to the story. As a result, this paper reviews the importance and weaknesses of previous video analysis methods ranging from content-based approaches to story analysis based on social network. Also, we suggest necessary elements, such as character, background, and events, based on narrative structures introduced in the literature. We extract characters' emotional words from the script of the movie Pretty Woman by using the hierarchical attribute of WordNet, which is an extensive English thesaurus. WordNet offers relationships between words (e.g., synonyms, hypernyms, hyponyms, antonyms). We present a method to visualize the emotional pattern of a character over time. Second, a character's inner nature must be predetermined in order to model a character arc that can depict the character's growth and development. To this end, we analyze the amount of the character's dialogue in the script and track the character's inner nature using social network concepts, such as in-degree (incoming links) and out-degree (outgoing links). Additionally, we propose a method that can track a character's inner nature by tracing indices such as degree, in-degree, and out-degree of the character network in a movie through its progression. Finally, the spatial background where characters meet and where events take place is an important element in the story. We take advantage of the movie script to extracting significant spatial background and suggest a scene map describing spatial arrangements and distances in the movie. Important places where main characters first meet or where they stay during long periods of time can be extracted through this scene map. In view of the aforementioned three elements (character, event, background), we extract a variety of information related to the story and evaluate the performance of the proposed method. We can track story information extracted over time and detect a change in the character's emotion or inner nature, spatial movement, and conflicts and resolutions in the story.

Recent Progress in Air-Conditioning and Refrigeration Research : A Review of Papers Published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2009 (설비공학 분야의 최근 연구 동향 : 2009년 학회지 논문에 대한 종합적 고찰)

  • Han, Hwa-Taik;Lee, Dae-Young;Kim, Seo Young;Choi, Jong-Min;Baik, Yong-Kyu;Kwon, Young-Chul
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.22 no.7
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    • pp.492-507
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    • 2010
  • This article reviews the papers published in the Korean Journal of Air-Conditioning and Refrigeration Engineering during 2009. It is intended to understand the status of current research in the areas of heating, cooling, ventilation, sanitation, and indoor environments of buildings and plant facilities. Conclusions are as follows. (1) Research trends of thermal and fluid engineering have been surveyed as groups of general thermal and fluid flow, fluid machinery and piping, and new and renewable energy. Various topics were covered in the field of general thermal and fluid flow such as an expander, a capillary tube, the flow of micro-channel water blocks, the friction and anti-wear characteristics of nano oils with mixtures of refrigerant oils, etc. Research issues mainly focused on the design of micro-pumps and fans, the heat resistance reliability of axial smoke exhaust fans, and hood systems in the field of fluid machinery and piping. Studies on ground water sources were executed concerning two well type geothermal heat pumps and multi-heat pumps in the field of new and renewable energy. (2) Research works on heat transfer area have been reviewed in the categories of heat transfer characteristics and industrial heat exchangers. Researches on heat transfer characteristics included the heat transfer in thermoelectric cooling systems, refrigerants, evaporators, dryers, desiccant rotors. In the area of industrial heat exchangers, researches on high temperature ceramic heat exchangers, plate heat exchangers, frosting on fins of heat exchangers were performed. (3) In the field of refrigeration, papers were presented on alternative refrigerants, system improvements, and the utilization of various energy sources. Refrigeration systems with alternative refrigerants such as hydrocarbons, mixed refrigerants, and $CO_2$ were studied. Efforts to improve the performance of refrigeration systems were made applying various ideas of suction line heat exchangers, subcooling bypass lines and gas injection systems. Studies on heat pump systems using unutilized energy sources such as river water, underground water, and waste heat were also reported. (4) Research trend in the field of mechanical building facilities has been found to be mainly focused on field applications rather than performance improvements. In the area of cogeneration systems, papers on energy and economic analysis, LCC analysis and cost estimating were reported. Studies on ventilation and heat recovery systems introduced the effect on fire and smoke control, and energy reduction. Papers on district cooling and heating systems dealt with design capacity evaluation, application plan and field application. Also, the maintenance and management of building service equipments were presented for HVAC systems. (5) In the field of architectural environment, various studies were carried to improve indoor air quality and to analyze the heat load characteristics of buildings by energy simulation. These studies helped to understand the physics related to building load characteristics and to improve the quality of architectural environment where human beings reside in.

An investigation of the User Research Techniques in the User-Centered Design Framework - Focused on the on-line community services development for 13-18 Young Adults (사용자 중심 디자인 프레임워크에서 사용자 조사기법의 역할에 관한 연구 - 13-18 청소년용 온라인 커뮤니티 컨텐트 개발 프로젝트를 중심으로)

  • 이종호
    • Archives of design research
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    • v.17 no.2
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    • pp.77-86
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    • 2004
  • User-Centered Design Approach plays important role in dealing with usability issues for developing modern technology products. Yet it is still questionable whether the User-Centered approach is enough for the development of successful consumer contents since the User-Centered Design is originated from the software engineering field where meeting customers' functional requirement is the most critical aspect in developing a software. However, modern consumer market is already saturated and in order to meet ever increasing consumer requirements, the User-Centered Design approach needs to be expanded. As a way of incorporating the User-Centered Approach into the consumer product development, Jordan suggested the 'Pleasure-based Approach' in industrial design field, which usually generates multi-dimensional user requirements: 1)physical, 2)cognitive, 3)identity and 4) social. It is the current tendency that many portal and community service providers focus on fulfilling both functional and emotional needs for users when developing new items, contents and services. Previously fulfilling consumers' emotional needs solely depend on visual designer's graphical sense and capability. However, taking the customer-centered approach on withdrawing consumers' unknown needs is getting critical in the competitive market environment. This paper reviews different types of user research techniques and categorized into 6 ways based on Kano(1992)'s product quality model. Based on his theory, only performance factors, such as suability, can be identified through the user-centered design approach. The user-centered design approach has to be expanded to include factors include personality, sociability, pleasure, and so on. In order to identify performance as well as excellent factors through user research, a user-research framework was established and tested through the case study, which is ' the development of new online service for teens '. The results of the user research were summarized at the end of the paper and the pros and cons of each research techniques were analyzed.

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A Study on the Designer's Post-Evaluation of Gyeongui Line Forest Park Based on Ground Theory - Focused on Yeonnam-dong Section - (근거이론을 활용한 설계자의 경의선숲길공원 사후평가 - 연남동 구간을 중심으로 -)

  • Kim, Eun-Young;Hong, Youn-Soon
    • Journal of the Korean Institute of Landscape Architecture
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    • v.47 no.3
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    • pp.39-48
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    • 2019
  • This research is based on the analysis of in-depth interviews of designers who participated in the design of the Yeonnam-dong section, which was completed in 2016. The case study site has received many domestic and foreign awards and is receiving very positive reviews from actual users. 53 concepts were derived from the open coding of the ground theory methodology. Thirty-four higher categories incorporated the concepts and 18 higher categories that reintegrated them. Later, the six categories of the ground theory were interpreted as the paradigm, and it was determined that the aspects of 'will of client' and 'work efficiency', 'site resources' and 'field manager's specialty' were the categories that had the greatest positive impact on the park construction. The key category of this park's construction was interpreted as "a park-construction model with active empathy and communication." The results of the study and are linked to the following research proposals. First, the need to improve the trust between the client and the landscape designer and the need to improve the customary administrative procedures; second, the importance of the input of landscape experts into the park construction process; third, the importance of all efforts to develop the design; fourth, the importance of on-site circular resources and landscape preservation; and fifth active social participation to increase the opportunity. This study, which seeks to grasp the facts that existed behind the park's construction, which received excellent internal and external evaluations, and has a qualitative, objective and structural interpretation of the social network related to the park's construction, in contrast to the conventional quantitative post-evaluation. It is expected that the administration and system improvements related to landscaping will be further improved through the continuation of in-depth post-evaluation studies.