• Title/Summary/Keyword: odd ratio

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Analysis of FHIT Gene Methylation in Egyptian Breast Cancer Women: Association with Clinicopathological Features

  • Zaki, Seham Mahrous;Abdel-Azeez, Hala A.;El Nagar, Mona Roshdy;Metwally, Khaled Abdel-Aziz;Ahmed, Marwa M. Samir S.
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.1235-1239
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    • 2015
  • Background: Fragile histidine triad (FHIT) gene is a tumor suppressor gene which involved in breast cancer pathogenesis. Epigenetics alterations in FHIT contributes to tumorigenesis of breast cancer. Objective: Our objective was to study FHIT promoter region hypermethylation in Egyptian breast cancer patients and its association with clinicopathological features. Materials and Methods: Methylation-specific polymerase chain reaction was performed to study the hypermethylation of FHIT promoter region in 20 benign breast tissues and 30 breast cancer tissues. Results: The frequency of hypermethylation of FHIT promoter region was significantly increased in breast cancer patients compared to bengin breast disease patients. The Odd's ratio (95%CI) of development of breast cancer in individuals with FHIT promoter hypermethylation (MM) was 11.0 (1.22-250.8). There were also significant associations between FHIT promoter hypermethylation and estrogen, progesterone receptors negativity, tumor stage and nodal involvment in breast cancer pateints. Conclusions: Our results support an association between FHIT promotor hypermethylation and development of breast cancer in Egyptian breast cancer patients. FHIT promoter hypermethylation is associated with some poor prognostic features of breast cancer.

Extraction Solution for the Coupling Coefficient at the Magnetically Coupled Wireless Power Transmission (자계 결합 무선 전력 전송에서의 결합 계수 추출 방법)

  • Kim, Gun-Young;Lee, Bom-Son
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.23 no.9
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    • pp.1073-1078
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    • 2012
  • This paper presented the extraction solution for the coupling coefficient at the magnetically coupled wireless power transmission(WPT) system through the analysis of its equivalent circuit considering the loss. The conventional extraction solution using coupled mode theory is generalized employing the extracted solution considering the load resistance. Consequently, the measuring process of extracting coupling coefficient becomes convenient since the even/odd mode analysis is not necessary. Furthermore, the coupling coefficient obtained from the induced extraction method was in excellent agreement with the coupling coefficient obtained using the ratio of magnetic flux passing through the two loops. The extraction of the accurate coupling coefficient at the magnetically coupled WPT is an essential work to analyze and optimize the WPT system.

Study on Biochemical Parameters and Body Fat Mass according to Leptin Receptor Polymorphism in University Students (렙틴 수용체 유전자 다형성에 따른 대학생의 생화학 지표와 체지방 분포에 관한 연구)

  • Kim, Kyung-Hee;Cho, Hee-Sook
    • Journal of the East Asian Society of Dietary Life
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    • v.22 no.2
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    • pp.219-223
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    • 2012
  • The purpose of this study was to investigate the body composition, biochemical parameters, and consumption of convenience foods according to leptin receptor polymorphism in university students. A survey was conducted on a total of 418 students - 271 males and 147 females. Based on a self-reporting method, questionnaires were administered for over 20 minutes, and leptin receptor and blood samples were analyzed. The genotype frequencies of leptin receptor polymorphism were Gln/Arg heterozygote (64.8%) and Gln/Gln homozygote (35.2%). Leptin polymormphism showed no significant association with biochemical parameters(ALT, cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, and hemoglobin) and body composition. GG homozygote was associated with a higher risk of visceral fat obesity compared to those with GA heterozygote (odd ratio 1.758, 95% confidence intervals 0.812~3.803). Leptin polymorphism appeared to be a genetic risk factor for visceral fat obesity. This study suggests that leptin polymorphism has a causative role to body fat distribution in Korean.

The Relationship between Emotional Working Hour and Muscle Pain (감정노동 수행시간과 근육통의 관련성)

  • Lee, Bokim
    • Korean Journal of Occupational Health Nursing
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    • v.23 no.4
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    • pp.269-276
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    • 2014
  • Purpose: The purpose of this study was to investigate muscle pains of emotional laborers and determine whether there were differences in their muscle pains depending on the hours spent on emotional labor. Methods: This is a secondary analysis of the data collected from the 3rd (2011) Korean Working Conditions Survey. 50,032 participants responded to the study's questionnaire. Among them, 15,669 participants were emotional laborers who directly dealt with people such as customers, passengers, pupils, patients, etc. Results: Thirty three percent of subjects had reported muscle pains. Muscle pains of subjects were positively related to the hours spent on emotional labor (p<.001). According to the logistic regression analysis, the adjusted odd ratio of the subjects who spent about almost all of the work hours on emotional labor was 1.32 (95% CI: 1.15~1.52), compared to the subjects who spent about a quarter of their work hours on emotional labor, when other factors were controlled. Conclusion: The study's findings indicate that engaging in emotional labor for longer hours increases the risks of muscle pains. Occupational nurses must pay closer attention to the management of muscle pains of emotional laborers.

Effects of health behaviors on the periodontal health status of Korea young man: The 6th Korean National Health and Nutrition Examination Survey (한국 청년의 치주건강에 대한 건강행태의 영향- 제6기 국민건강영양조사)

  • Han, Su-Jin
    • Journal of Korean society of Dental Hygiene
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    • v.18 no.6
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    • pp.957-967
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    • 2018
  • Objectives: The aim of this study was to confirm health behaviors that affect periodontal health status. Based on these results, we also intended to provide information for the prevention of gingivitis prior to periodontitis and establish strategies for maintaining healthy periodontal tissues. Methods: Data for this descriptive study were extracted from the Korea National Health and Nutrition Examination Survey 2013-2015. A total of 2,710 adults, aged 19-39 years were included in this study. Complex logistic regression analyses were performed to confirm relationships between health behaviors and periodontal health, after adjusting for socio-demographics, oral and systemic health status. Results: Dental clinic visits (odd ratio [OR] = 1.761, 95% confidence interval [CI]; 1.391-2.229), use of floss (OR = 1.504, 95% CI; 1.213-1.865), and non-smoking (OR = 1.269, 95% CI; 1.040-1.549) were found to support periodontal health. Conclusions: Dental visits for continued professional oral health care, self-oral care including interdental flossing, and a non-smoking habit, are necessary for periodontal health maintenance. Additionally, the results suggest that physical activities such as regular walking can help. These methods should be considered as the primary preventative care strategies for minimizing the occurrence of gingival inflammation.

Use of N-alkanes to Estimate Intake and Digestibility by Beef Steers

  • Premaratne, S.;Fontenot, J.P.;Shanklin, R.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.11
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    • pp.1564-1568
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    • 2005
  • The objective of the study was to evaluate the use of n-alkanes to estimate DM intake and digestibility by beef cattle. Six steers were blocked (3 blocks, 2 animals/block) according to the body weight (279${\pm}$19 kg) and randomly allotted within blocks to two diets (3 steers/diet). A second trial was conducted with the same animals (321${\pm}$18 kg) after 36 days (d), using a switch back design. The diets consisted of two types of chopped sun-cured hay, alfalfa (Medicago sativa L) hay, or fescue (Festuca arundinacea Schreb) and alfalfa mixture, which were fed in equal amounts to steers. Animals were dosed with $C_{32}$ and $C_{36}$ alkanes, employing an intra-ruminal controlled-release device at the beginning of each trial. Hay intake per animal was measured from d 6 to 12 and sub samples were taken for chemical analysis. Rectal samples of feces were taken from each animal once/daily from d 8 to 14, freeze dried, and ground prior to alkane analysis. Alkanes were extracted from ground hay and feces. Feed intake was calculated from the dose rate of $C_{32}$ alkane and, the herbage and fecal concentrations of adjacent odd ($C_{33}$ or $C_{31}$) and even ($C_{32}$) chain length alkanes. Crude Protein, NDF, ADF, ash concentrations and In vitro dry matter digestibility (IVDMD) were 17.7, 42.2, 28.4, 7.9 and 71.7 for alfalfa, and 12.4, 56.5, 30.4, 6.9 and 69.1% for fescue/alfalfa mixture, respectively. For both diets, intake estimated from $C_{33}$:$C_{32}$ ratio was not different from the measured intake, but intake estimated from $C_{31}$:$C_{32}$ ratio was lower (p<0.05), than the measured intake for both diets. The average estimated forage intake from $C_{33}$:$C_{32}$ ratio was 4.86 and 0.69% below than the measured intake for alfalfa and, fescue/alfalfa mixed diets, respectively. The respective estimates with $C_{31}$:$C_{32}$ ratio were 9.59 and 11.33% below than the measured intake. According to these results, alkane $C_{33}$:$C_{32}$ ratio is better than alkane $C_{31}$:$C_{32}$ ratio for the estimation of intake by beef steers.

A Study on the Taegeuk Shaped Directional Coupler with Improved Power Split Ratio (개선된 전력 분배율을 갖는 태극형 방향성 결합기에 관한 연구)

  • 양규식;오양현;이종악
    • The Proceeding of the Korean Institute of Electromagnetic Engineering and Science
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    • v.2 no.2
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    • pp.19-24
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    • 1991
  • This paper propose a new taegeuk shaped directional couper and verify the possibility of high power division rate in those directional coupler through the experiments. We took the taegeuk shaped structure in those proposed directional coupler to utilize a $3\lambda/4$ section of hybrid ring directional coupler actively, and calculated the branch admittances, which satisfied the condition of perfect matching and isolation in the center frequency, by even odd mode analyzing methodes. On the result, we knew that it can be realized a much higher power division rate than reported result in same circuit area within the producible resistance limit in the microstrip line, made the taegeuk shaped directional couplers with 0, 8, 16 dB power split ratio in the 10 GHz frequency using CGP - 502 plate, and confirmed the validity of theory through the experiments.

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Wideband Power Divider Using a Coaxial Cable (동축선을 이용한 광대역 전력 분배기)

  • Park, Ung-Hee
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.16 no.4
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    • pp.661-668
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    • 2012
  • A coaxial-cable impedance transformer that can be used in high power and wideband frequency range is an arbitrary impedance transformation ratio by an additional coaxial cable. The coaxial-cable impedance transformer to be 50-${\Omega}$ to 25-${\Omega}$ impedance transformation ratio is easily operated an wideband power divider by connecting two 50-${\Omega}$ lines at 25-${\Omega}$ impedance point. This wideband power divider has a poor output matching characteristic and a poor isolation characteristic between two output ports. In this paper, it proposes a coaxial-cable power divider to be a good output matching and isolation characteristics as it uses the singly terminated filter design theory. The odd-mode operation characteristic of the suggested power divider to use singly terminated low pass filter coefficient due to matching order and ripple value is examined by ADS program. And, it fabricates and measures the operation characteristic of 2-way power divider with 2nd-order and 4th-order matching circuit.

Flight Activities of Larger Black Chafer (Holotrichia morosa Waterhouse) and Korean Black Chafer (H. diomphalia Bates) (큰검정풍뎅이와 참검정풍뎅이 성충의 비상활동)

  • 김기황
    • Korean journal of applied entomology
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    • v.29 no.4
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    • pp.222-229
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    • 1990
  • The flight activities of Holotrichia morosa Watershouse and H. diomphaia Bates adults were monitored by blacklight traps for six years from 1984 to 1989. The flight activity of H. morosa adults was most prominent from late June to early August with a peak flight in mid July, and that of H. diomphalia adults mainly occurred from early May to late June of odd years with the peak flight dates varying year by year. The flight activities of the two species during the fight period became vigorous after moderate to heavy rainfalls. The overwintered adults of H. diomphalia seemed to begin flying when the daily mean temperature rose above $15^{\circ}C$. The ratios of the females to the total adults collected by the blacklight traps were 53.3% for H. morosa and 0% for H. diomphalia, although the female sex ratio of the latter species was 57.4% in the field.

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Gender Differences in the Relationship between Alcohol Use Behaviors and Metabolic Syndrome - Korean National Health and Nutrition Examination Survey (KNHANES) V 2010 - (성별에 따른 알코올사용행태와 대사증후군과의 관계 - 제5기 2010년 국민건강영양조사 자료를 이용하여 -)

  • Ryu, Ji Young;Kim, Dae-Hwan
    • Korean Journal of Health Education and Promotion
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    • v.30 no.1
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    • pp.83-93
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    • 2013
  • Objectives: The objective of this study was to assess the gender differences in the relationship between alcohol use behaviors and the risk of metabolic syndrome among Korean adult population. Methods: Data from the Korean National Health and Nutrition Examination Survey (5th, 2010) was analyzed. Using the Alcohol Use Disorders Identification Test, subjects were classified into 4 groups including non-drinking, low-risk drinking, medium-level alcohol problem, and high-level alcohol problem group. Metabolic syndrome and its components were compared among the alcohol behavior groups by gender. Results: The odds ratio vs. non-drinking group for metabolic syndrome was significantly higher in male medium and high-level alcohol problem group. In female, high-level alcohol problem group showed significantly higher odds ratio for metabolic syndrome. Blood pressure and HDL-cholesterol were likely to be higher with the excessive drinking behaviors in both men and woman. Triglyceride level in men was significantly higher in the medium and high-level alcohol problem group than non-drinking group. Although fasting glucose level did not show differences among drinking groups, the odd ratios vs. non-drinking group for the hyperglycemia (${\geq}$ 100mg/dl) were significantly higher in female drinking groups. Conclusions: Problematic alcohol drinking is likely to increase the risk of metabolic syndrome in Korean adults.