• Molecules and Cells
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• v.37 no.4
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• pp.286-294
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• 2014

Mammalian polo-like kinase 1 (Plk1) has been studied intensively as a key regulator of various cell cycle events that are critical for proper M-phase progression. The polobox domain (PBD) present in Plk1's C-terminal noncatalytic region has been shown to play a central role in targeting the N-terminal kinase domain of Plk1 to specific subcellular locations. Subsequent studies reveal that PBD binds to a phosphorylated motif generated by one of the two mechanisms - self-priming by Plk1 itself or non-self-priming by a Pro-directed kinase, such as Cdc2. Here, we comparatively review the differences in the biochemical steps of these mechanisms and discuss their physiological significance. Considering the diverse functions of Plk1 during the cell cycle, a better understanding of how the catalytic activity of Plk1 functions in concert with its cisacting PBD and how this coordinated process is intricately regulated to promote Plk1 functions will be important for providing new insights into different mechanisms underlying various Plk1-mediated biological events that occur at the multiple stages of the cell cycle.

• Nuclear Engineering and Technology
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• v.45 no.2
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• pp.203-210
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• 2013

The objective of this conducted research is to study the iodine removal efficiency in a self-priming venturi scrubber for submerged and non-submerged operating conditions experimentally and theoretically. The alkaline solution is used as an absorbent, which is prepared by dissolving sodium hydroxide (NaOH) and sodium thiosulphate ($Na2S_2O_3$) in water to remove the gaseous iodine ($I_2$) from the gas. Iodine removal efficiency is examined at various gas flow rates and inlet concentrations of iodine for submerged and non-submerged operating conditions. In the non-submerged venturi scrubber, only the droplets take part in iodine removal efficiency. However, in a submerged venturi scrubber condition, the iodine gas is absorbed from gas to droplets inside the venturi scrubber and from bubbles to surrounding liquid at the outlet of a venturi scrubber. Experimentally, it is observed that the iodine removal efficiency is greater in the submerged venturi scrubber as compare to a non-submerged venturi scrubber condition. The highest iodine removal efficiency of $0.99{\pm}0.001$ has been achieved in a submerged self-priming venturi scrubber condition. A mathematical correlation is used to predict the theoretical iodine removal efficiency in submerged and non-submerged conditions, and it is compared against the experimental results. The Wilkinson et al. correlation is used to predict the bubble diameter theoretically whereas the Nukiyama and Tanasawa correlation is used for droplet diameter. The mass transfer coefficient for the gas phase is calculated from the Steinberger and Treybal correlation. The calculated results for a submerged venturi scrubber agree well with experimental results but underpredicts in the case of the non-submerged venturi scrubber.

• Restorative Dentistry and Endodontics
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• v.28 no.3
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• pp.203-208
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• 2003

The purpose of this study was to evaluate the effect of salivary contamination of teeth on bonding efficacy of self-priming and self-etching DBSs. The materials used were Single Bond(SB, self-priming system, 3M), Unifil Bond(UB, self-etching system, GC), and Scotchbond Multi-Purpose Plus(SM, 3M) as control. Forty five human molars randomly allocated to three groups as dentin bonding systems tested and embedded in epoxy resin. Then the specimens were wet-ground to expose flat buccal enamel surface or flat occlusal dentin surface and cut bucco-lingually to form two halves with slow speed diamond saw. One of them was used under non-contamination, other under contamination with saliva. The bonding procedure was according to the manufacturer's directions and resin composite(Z-100, 3M Dental Products, St. Paul, MN) was built-up on the bonded surface 5mm high. The specimens were ground carefully at the enamel-composite interface with fine finishing round diamond bur to create an hour-glass shape yielding bonded surface areas of $1.5{\pm}0.1\textrm{mm}^2$. The specimens were bonded to the modified microtensile testing apparatus with cyanoacrylate, attached to the universal testing machine and stressed in tension at a CHS of 1mm/min. The tensile force at failure was recorded and converted to a tensile stress(MPa). Mean values and standard deviations of the bond strength are listed in table. One-way ANOVA was used to determine significant difference at the 95% level. The bond strength of SBMP and SB were not affected by salivary contamination, but that of UB was significantly affected by salivary contamination. These results indicate that DBSs with total etch technique seems less likely affected by salivary contamination in bonding procedure.

• Nuclear Engineering and Technology
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• v.54 no.9
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• pp.3310-3316
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• 2022

Owing to the rising concerns about the safety of nuclear power plants (NPP), it is essential to study the venturi scrubber in detail, which is a key component of the filtered containment venting system (FCVS). FCVS alleviates the pressurein containment byfiltering and venting out the contaminated air. Themain objective of this research was to perform a CFD investigation of different configurations of a circular, non-submerged, self-priming venturi scrubber to estimate and improve the performance in the removal of elemental iodine from the air. For benchmarking, a mass transfer model which is based on two-film theory was selected and validated by experimental data where an alkaline solution was considered as the scrubbing solution. This mass transfer model was modified and implemented on a unique formation of two self-priming venturi scrubbers in series. Euler-Euler method was used for two-phase modeling and the realizable K-ε model was used for capturing the turbulence. The obtained results showed a remarkable improvement in the removal of radioactive iodine from the air using a series combination of venturi scrubbers. The removal efficiency was improved at every single data point.

• The Journal of the Korea Contents Association
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• v.21 no.9
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• pp.493-501
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• 2021

This study started to examine the understanding and perception of 'disabled people' and 'non-disabled people', one of the dichotomous elements in the 21st century social integration era. In particular, for the analysis, Q-methodology, which should respond based on the respondent's inner self and perception, was used. For the analysis, 32 Q-statements were secured, and as a result of targeting 20 P-sample respondents, three types were derived as follows. In , statements such as 'A correct awareness of disability is necessary' and 'Disability can occur to anyone' are emphasized, so it was named 「Correct Perception Emphasis Type」. emphasized 'The life of the disabled is not easy' and 'The disabled need an opportunity to participate in society' and was named 「The Life of the Disabled Understanding Type」. emphasized statements such as 'Economic support is necessary for the disabled' and 'The welfare budget for the disabled must be sufficiently secured', and was named 「Institutional Support Emphasis Type」. Therefore, in addition to the necessity of correct recognition of disability and disability in our society, we expect this study result is to be priming water for improving the recognition of the disabled.

• Korean Journal of Culture and Social Issue
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• v.14 no.1
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• pp.101-123
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• 2008

We investigated the implicit representations of success/failure associated with mother in male and female college students. In study 1, participants were presented 'mother' or 'basket' as a context prime and 'success' or 'failure' related words as second primes for 100ms, and were asked to make lexical decisions about 'accept' or 'reject' related words and non-words after 150 ms (SOA 250ms). Results revealed that lexical decision times on the mother condition were more rapid than the ones on the basket condition, and lexical decision times on the acceptance condition were more rapid than the ones on the rejection condition, and female participants showed shorter times than male students did. In study 2, we divided participants into four groups by gender and attachment style, Results showed that the interaction between success/failure and acceptance/rejection was statistically significant, that is, quickest lexical decision times on the success-acceptance condition, and slowed times on failure-acceptance, failure-rejection, and success-rejection condition in order. On the other hand, no significant differences between high and low attachment group were found in males, but significant three-way interactions were found in females. In highly attached females, lexical decision times in success-acceptance condition were not differed from ones in success-rejection condition, and slowed times in failure-rejection condition. Low attached females showed very rapid times in success-acceptance condition, but very slow times in success-rejection condition. The results were discussed in terms of self-positivity and success/failure scheme depending on gender and attachment styles.

• Journal of the korean academy of Pediatric Dentistry
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• v.29 no.1
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• pp.57-68
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• 2002

The purpose of this study was to evaluate microleakage of etched and non-etched amalgam restorations lined with dentin bonding system primer and adhesives. Class V amalgam preparations were made in 100 extracted human premolars divided into 10 groups with 10 teeth each. SEM was taken to assess the dentin/amalgam interface. The results were as follows; 1. At the occlusal and gingival margins, all experimental groups showed lower leakage value than unlined group(p<0.05) The $Copalite^{(R)}-lined$ group showed higher leakage value than other experimental groups(p<0.05). 2. In all experimental groups, the gingival margin showed higher leakage value than the occlusal margin. 3. There were no significant difference between non-etching and etching groups, primer only and primer & adhesive groups, primer & adhesive and self-priming adhesive groups(p>0.05). 4. On the SEM observation, continuous gaps were observed in the unlined and $Copalite^{(R)}-lined$ groups, but the gaps were filled with primer or adhesive layer in other experimental groups.