• Journal of the Korean Geographical Society
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• v.50 no.2
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• pp.239-254
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• 2015

The purpose of this study is to explore the possibility of ethical geography education, based on the 'relational turn' of understanding of human/non-humans and place in the context of the student's daily consumption. To do this, first and foremost, due to the de-localization of product networks that students consume, it has been discussed the situation that the ethics of responsibility and care is reduced. Then, this paper suggests an understanding of place and human/non-humans in a relational view, as a basis for the student's ability to look at matters of consumption and ethics through the viewpoint of relational ethics of responsibility and care. Finally, this research examined relation of commodity consumption, relational geographies and ethics of responsibility and care through 'mobile phone connection'. It is argued in the paper that the role of ethical geography education lies also in allowing students to feel connected to various humans/non-humans as a absent presence in his own life and to acquire cognitive and practical skills to provide more responsibility and care for their socio-ecological environment, thus making a better world.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.41 no.7
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• pp.673-682
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• 2017

As the culture of making things based on "do-it-yourself" (DIY) activity is increasingly promoted, the use of recent digital technologies and tools, including the 3D printer, have become widespread. However, the use of computerized numerical control (CNC) engraving machine is considered difficult because of the complicated procedures and specialized knowledge required for its operation. Therefore, this study aims to resolve the issue that limits the usability of the CNC engraving machine. This paper presents a novel CNC engraving machine system for non-experts based on human-centered design. First, the size and type of the workpiece and tool are reduced. Second, computer-aided process planning (CAPP) steps such as tool path generation, workpiece clamping, and corresponding coordinate system are automated by compromising productivity and efficiency. As a result, a CNC engraving machine system that can be easily used by non-experts was developed. This development has great significance in that it opens up the possibility of using the CNC engraving machine for a wider range of DIY activities.

• Journal of the East Asian Society of Dietary Life
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• v.23 no.2
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• pp.133-140
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• 2013

The purpose of this study was to investigate perception and awareness of yaksun and willingness to eat yaksun in the future, and to examine the factors affecting intake behavior of yaksun of adults in Daegu and Gyeongbuk region. The data were collected in April, 2011 through a self-administered questionnaire. Chi-square test, t test, and binary logistic regression were conducted by SPSS Windows V.19.0. The results were as follows. Almost sixty-six percent of the respondents answered that they knew yaksun. The perception level of yaksun for the intake respondents was higher than that of non-intake respondents. Additionally, many respondents agreed to varied menu development and convenient-food development of yaksun. Intake respondents showed higher level of agreement for the varied menu development of yaksun than non-intake respondents. On the other hand, four fifths of the respondents showed that they would be willing to eat yaksun in the future. The level of willingness to eat yaksun in the future for the intake respondents was higher than that of non-intake respondents. Additionally, the respondents who knew yaksun showed higher level of willingness to eat it than those who did not know it. Finally, the result of binary logistic regression analysis for intake behavior of yaksun showed that gender, educational level, and the awareness of yaksun were significant. On the basis of these results, not only the promotion of yaksun to consumers but also the development of convenient foods, varied menus for different age groups, and menus with cheap prices are needed to raise yaksun popularity.

• Bulletin of the Korean Chemical Society
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• v.34 no.11
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• pp.3444-3450
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• 2013

Three phase hollow fiber-liquid phase microextraction (HF-LPME), which is faster, simpler and uses a more environmentally friendly sample-preparation technique, was developed for the analysis of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in human urine. For the effective simultaneous extraction/concentration of NSAIDs by three phase HF-LPME, parameters (such as extraction organic solvent, pH of donor/acceptor phase, stirring speed, salting-out effect, sample temperature, and extraction time) which influence the extraction efficiency were optimized. NSAIDs were extracted and concentrated from 4 mL of aqueous solution at pH 3 (donor phase) into dihexyl ether immobilized in the wall pores of a porous hollow fiber, and then extracted into the acceptor phase at pH 13 located in the lumen of the hollow fiber. After the extraction, 5 ${\mu}L$ of the acceptor phase was directly injected into the HPLC/UV system. Simultaneous chromatographic separation of seven NSAIDs was achieved on an Eclipse XDB-C18 (4.6 mm i.d. ${\times}$ 150 mm length, 5 ${\mu}m$ particle size) column using isocratic elution with 0.1% formic acid and methanol (30:70) at a HPLC-UV/Vis system. Under optimized conditions (extraction solvent, dihexyl ether; $pH_{donor}$, 3; $pH_{acceptor}$, 13; stirring speed, 1500 rpm; NaCl salt, 10%; sample temperature, $60^{\circ}C$; and extraction time, 45 min), enrichment factors (EF) were between 59 and 260. The limit of detection (LOD) and limit of quantitation (LOQ) in the spiked urine matrix were in the concentration range of 5-15 ng/mL and 15-45 ng/mL, respectively. The relative recovery and precision obtained were between 58 and 136% and below 15.7% RSD, respectively. The calibration curve was linear within the range of 0.015-0.96 ng/mL with the square of the correlation coefficient being more than 0.997. The established method can be used to analyse of NSAIDs of low concentration (ng/mL) in urine.

• IMMUNE NETWORK
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• v.7 no.3
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• pp.117-123
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• 2007

Background: This study was designed to investigate the role of the hepatocyte growth factor (HGF) with regards to differentiation of somatic stem cells originating from the human umbilical cord blood (UCB) into hepatic lineage cells in vitro culture system. Methods: Mononuclear cells from UCB were cultured with and without HGF based on the fibroblast growth factor (FGF)-1, FGF-2, and stem cell factor. The cultured cells were confirmed by immunofluorescent staining analysis with albumin (ALB), cytokeratin-19 (CK-19), and proliferating cell nuclear antigen (PCNA) MoAb. ALB and CK-18 mRNA were also evaluated by reverse transcription-polymerase chain reaction. In order to observe changes in proliferating capacity with respect to the cultured period, CFSE with affinity to proliferating cells were tagged and later underwent flow cytometry. Results: In the HGF-treated group, cultured cells had a large oval shaped appearance with adherent, but easily detachable characteristics. In the HGF-non treated group, these cells were spindle-shaped with strong adherent characteristics. Expressions of ALB and CK-19 were evident in HGF-treated group compared to non-expression of those in to HGF-non treated group. Dual immunostaining analysis of the ALB producing cells showed presence of PCNA in their nuclei, and ALB and CK-18 mRNA were detected on the 21st day of cultured cells in the HGF-treated group. Conclusion: Our findings suggest that HGF has a pivotal role in differentiating somatic stem cells of human UCB into hepatic lineage cells in vitro.

• The Journal of the Convergence on Culture Technology
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• v.7 no.2
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• pp.275-280
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• 2021

This study began with the question of obtaining human resources through the promotion of outstanding resources of the Special Forces Officer and studied the following four promotion strategies: First, it is Facebook's promotional strategy medium. Second, it is a promotional strategy medium of YouTube. Third, it is a promotional strategy medium for blogs. Fourth, it is a public relations strategy medium for Web site. Furthermore, we would like to consider this study through four promotional strategies and cases of acquiring excellent foreign personnel in order to acquire excellent non-commissioned officers. Therefore, it is necessary to obtain excellent resources through promotional activities by utilizing strategic intermediaries for obtaining excellent resources from special forces. Ultimately, this study can provide fundamental implications for recruiting special forces officers for obtaining excellent resources by utilizing strategic intermediaries.

• Journal of Physiology & Pathology in Korean Medicine
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• v.35 no.4
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• pp.117-123
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• 2021

Gefitinib, a first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI), provides obvious clinical benefit in patients with EGFR-mutant non-small cell lung cancer (NSCLC). However, patients ultimately develop gefitinib resistance which mainly caused by EGFR T790M secondary mutation. In the current study, we investigated whether the root extract of Scutellaria baicalensis (SB) overcomes gefitinib resistance. Gefitinib-resistant H1975 human NSCLC cells (EGFR L858R/T790M double mutant) were treated with gefitinib and/or ethanol extract of SB (ESB) to evaluate the effect of ESB on the gefitinib sensitivity. The cell viability was measured by MTT assay and trypan blue exclusion assay. The colony-forming ability was evaluated by anchorage-dependent colony formation assay. Combined treatment with gefitinib and ESB markedly decreased the cell viability and colony formation than single treatment with gefitinib or ESB in H1975 cells. In addition, cells treated with both gefitinib and ESB exhibited a significant increase of sub-G1 DNA content which indicates apoptotic cells compared with those treated with gefitinib or ESB alone. As a molecular mechanism, combined treatment with gefitinib and ESB strongly downregulated the phosphorylation of ERK and JNK than single treatment with gefitinib or ESB. Taken together, our results demonstrate that ESB sensitizes H1975 cells to gefitinib treatment. We cautiously propose that ESB can be used in combination with gefitinib for the advanced NSCLC patients with acquired resistance to EGFR TKIs.

• Journal of the Korean Society of Clothing and Textiles
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• v.23 no.4
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• pp.551-562
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• 1999

This study was intended to investigate the effect on the human body such as subcutaneous fat thickness the circumference of extremities etc. of the clothing training of putting on thin clothes periodically from the cold period. The subjects were divided into the clothing training group and the non-training group, The training group was asked to wear cool clothes in daily life and to wear the training clothes of T-shirts with half-length sleeves and pants and perform the clothing training for two hours daily three times a week in a cold environment over the period from November to February. The non-training group was asked to lead a life wearing comfortable clothes. Then a comparative experiment was conducted at 15$\pm$1$^{\circ}C$, 50$\pm$5% R, H and 0.25m/sec before and after the clothing training. After the clothing training regardless of gender subcutaneous fat thickness was more increased and total clothing weight per the surface area of the body was decreased in the training group than the non-training group. The training group showed lower skin temperature in the limbs and lower average skin temperature than the non-training group irrespective of gender which proved the effect of the clothing training. The training group was shown to have attendancy toward a greater sense of warmth and a less sense of discomfort which proved the effect of the clothing training.

• Korean Journal of Applied Biomechanics
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• v.17 no.2
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• pp.83-91
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• 2007

This experiment studied the change in a human's control of his or her static posture by analyzing the stabilogram diffusion and, by using the said study, evaluated the control ability of different groups with different experiences. The postures had a rising requirement of heel-rise according to three conditions: heel-toe, ball, toe; the groups were divided into dance major student and non-dance majors. The results of the critical points according to posture did not show a direct relation with the change in postures that had a rising requirement of heel-rise. The diffusion coefficient(D) had greater stochastic activity for short-term regions that utilize open-loop controls without feedback than for long-term regions that used closed-loop controls with feedback to maintain balance. The directional results of the body undergoing disturbance showed that A/P direction's diffusion coefficient (D) was larger than that of M/L direction. Both feet's planar diffusion coefficients were a linear combination of the diffusion coefficients calculated for the x and y axis. In studying the different abilities to control posture between a dance major student and a non-dance majors, a comparison of open-loop control's diffusion coefficient(D) was effective, and dance major student had superior control ability to that of non-dance majors.

• Journal of the Korean Home Economics Association
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• v.49 no.1
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• pp.67-78
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• 2011

The purposes of this study were to explore the differences in maternal parenting behaviors, parents' conflict, social support, and social competence according to boys' and girls' depression level. The participants of this study were 150 children of 4 to 6 grades and their teachers from one elementary school in Seoul. The data were analyzed using descriptive statistics and t-test. The result were as follows: Firstly, depressive boys perceived less maternal warmth and more parents' conflict than non-depression group. And boys of depression group had less task orientation than non-depression group. Secondly, depressive girls perceived less maternal warmth, supervision, and parents' support, and more parents' conflict than non-depression group. And girls of depression group were rated having less peer social skills, frustration tolerance than non-depression group by teachers.