• YAKHAK HOEJI
• /
• v.45 no.3
• /
• pp.245-250
• /
• 2001

Aminoacyl tRNA synthetases of bacteria are known as potential targets for new anti-microbial agents. To isolate new inhibitors of bacterial methionyl-tRNA synthetases from natural sources, a new target-oriented screening system using whole cells which are over-expressing a target enzyme was developed. Approximately 8,000 culture broths of microorganisms from soils were tested by this screening system. Among them, ten culture broths was found to contain inhibitory activity against methionyl -tRNA synthetases of Escherichia coli. For the validation of the screening system, this new method was compared with in vitro enzymatic method. Seven out of 10 culture broths showed inhibitory activity against methionyl-tRNA synthetases of E. coli. This result showed that the new screening system was comparable to the enzyme assay. Thus we believe that our screening system as a new method can be applied for the screening of new antibiotics inhibiting bacterial methionyl-tRNA synthetases from natural products.

• Korean Journal of Applied Biomechanics
• /
• v.21 no.2
• /
• pp.153-159
• /
• 2011

The purpose of this study was to develop an innovative training model and method to improve the posture and motion, while pulling up during weight lifting by evaluating the problems of Korean weight lifters performing this motion. To investigate the effectiveness of the new training method substitute members of the Korean national weight lifting team performed both the original pull up technique and new pulling training technique while kinetics and kinematics were recorded. For this study, the first phase of the new training method is more appropriate than the original training with the pull up drop slow deadlift to the knee joint. For the second phase, the new training motion is deemed to be more effective than the current box deadlift motion. Also, this new motion corrects the posture as there is more anterior hip joint motion(about 10 cm) and the knee flexes to about 120 degrees. For the third phase, starting about 10cm above the knee the box snatch high pull up is identified as a more suitable training method. For the forth phase, the box top snatch method is judged to be a more effective training method than the original top snatch training method.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 1997.10a
• /
• pp.209-213
• /
• 1997

This paper deals with sensing ability of $2^{nd}$ smart sensor that has a sensing ability of distinguish materials. We have developed new signal processing method that have distinguish different materials. We made the $2^{nd}$ smart sensor for experiment. The second type of smart sensor is HH type. We have developed a new signal processing method that can distinguish among different materials. The estimation method (RSAIIn dex) is developed for $2^{nd}$ smart sensor(HH smart sensor). Experiment and analysis are executed for estimation the new method. We estimated sensing ability of $2^{nd}$ smart sensor with RsA, method. Sensing Ability of the $2^{nd}$ smart sensor were evaluated relatively through a new RsAl method. According to frequency changing, influences of the $2^{nd}$ smart sensor are evaluated through a new recognition index RSAI. Applications of this method are for finding abnormal conditions of objects (automanufacturing), feeling of objects (medical product), robotics, safety diagnosis of structure, etc.

• Industrial Engineering and Management Systems
• /
• v.8 no.1
• /
• pp.22-28
• /
• 2009

We consider facility layout problems, where mn facility units are assigned into mn cells. These cells are arranged into a rectangular pattern with m rows and n columns. In order to solve this cell type facility layout problem, many approximation algorithms with improved local search methods were studied because it was quite difficult to find exact optimum of such problem in case of large size problem. In this paper, new algorithms based on Simulated Annealing (SA) method with two neighborhood generation methods are proposed. The new neighborhood generation method adopts the exchanging operation of facility units in accordance with adjacent preference. For evaluating the performance of the neighborhood generation method, three algorithms, previous SA algorithm with random 2-opt neighborhood generation method, the SA-based algorithm with the new neighborhood generation method (SA1) and the SA-based algorithm with probabilistic selection of random 2-opt and the new neighborhood generation method (SA2), are developed and compared by experiment of solving same example problem. In case of numeric examples with problem type 1 (the optimum layout is given), SA1 algorithm could find excellent layout than other algorithms. However, in case of problem type 2 (random-prepared and optimum-unknown problem), SA2 was excellent more than other algorithms.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.26 no.6D
• /
• pp.961-968
• /
• 2006

Curbs and L-type gutters installed at the edge of a road are very important structures to protect pedestrians from traffic accidents and to restraint slip of cars due to rain. However, existing construction method where great parts of the construction progress are done by human power has many problems in workability, quality and cost etc. In this paper, a new construction method for improvement in workability and quality for curbs and L-type gutters is developed. In order to investigate the structural safety and quality of curbs and gutters installed by the new method, tensile and lateral load tests are performed on curbs installed by existing and new methods and uniaxial compression tests are also performed on concrete samples of gutters constructed by existing and new methods. The test results show that the alignment of curbs and the strength of gutter concrete are very much improved by applying the new method. The tensile and lateral load capacities of the curbs installed by the new method are 10.7 and 2.5 times higher than those of curbs by existing method, respectively.

• The Transactions of the Korean Institute of Electrical Engineers A
• /
• v.53 no.1
• /
• pp.7-12
• /
• 2004

The role of protective relay with correct setting value is very important for the reliable operation of power : system. The setting process of a protective relay is difficult and requires hard work of calculations. Therefore, KEPCO as been using PROSET2000, a computer program system, in order to automate the setting process of protective relays in power transmission network since 2000. This system has a database and relay setting modules for each type of realy with coresponding Human and Computer Interaction(HCI). For the setting of a new type of relay, it require a new module, a HCI and a database table corresponding to the new relay. But it's update is not easy in case of new type of relay. This paper discussed the update method introducing a concept of Open Interface. It addressd a method to make a new HCI for new relay in view of object-oriented method using UML(Unified Modeling Language). Using the UML, we updated the PROSET2000. HCI screens for a new relay is generated automatically using the information of the new relay stored in the database. And, the database management module is upgraded to solve problems in manage and maintain the database in view of Open Interface.

• Transactions of the Korean Society for Noise and Vibration Engineering
• /
• v.16 no.11 s.116
• /
• pp.1149-1157
• /
• 2006

Donoho et al. suggested a wavelet thresholding denoising method based on discrete wavelet transform. This paper proposes an improved denoising method using a new thresholding function based on translation-invariant wavelet for underwater acoustic measurement. The conventional wavelet thresholding denoising method causes Pseudo-Gibbs phenomena near singularities due to the lack of translation-invariant of the wavelet basis. To suppress Pseudo-Gibbs phenomena, a denoising method combining a new thresholding function based on the translation-invariant wavelet transform is proposed in this paper. The new thresholding function is a modified hard-thresholding to each node according to the discriminated threshold so as to reject unknown external noise and white gaussian noise. The experimental results show that the proposed method can effectively eliminate noise, extract characteristic information of radiated noise signals.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
• /
• 2000.04a
• /
• pp.157-162
• /
• 2000

Discriminant analysis is a method to relate whether the objects have a specific characteristic or not with their 'continuous' attribute values and, for given objects, to estimate whether they have a specific characteristic or not by their values of discriminant scores gotten from their attribute values. The author developed the new 'computational' method of discriminant analysis without specific hypotheses or assumptions and, by this new method, we can find 'feasible' solutions under the conditions required by our actual problems. In this paper, the author tried to apply this new method to the discrimination of logical relations. If this trial could be a success, we can apply this new method of discriminant analysis to the problems about relating the specific characteristic of the objects with their 'discrete' attribute values. The result was successful and the applicability of discriminant analysis could be expanded as a method for constructing the models for "estimating impressions".

• Journal of the Korean Institute of Navigation
• /
• v.17 no.1
• /
• pp.17-29
• /
• 1993

The new flexible controlling method integrated with some existing maneuvers of reducing a great head way during approaching a pilot station or anchor berth, namely , Super Rudder (Woo) controlling method originally was developed. The conclusions of this paper are drawn. 1) Super Rudder (Woo) controlling method has the shortest distance along base course and distance off base course among all reducing maneuvers including Rudder Cycling. 2) This new method is flexibly adjustable to a range of yaw angles 5-35 degrees either ship's side depending on traffic situations, 3) This new method is versatile controlling maneuver enabling shipandlers to reduce or stop a ship's headway and to adjust the proper courses to a pilot station or anchor berth.

• Journal of applied mathematics & informatics
• /
• v.38 no.5_6
• /
• pp.519-532
• /
• 2020

In this paper, we first propose a new total variation-based regularization model for image restoration. We next propose a fixed-point-like method for solving the new image restoration model, and then we provide convergence analysis for the fixed-point-like method. To evaluate the feasibility and efficiency of the fixed-point-like method for the new proposed total variation-based regularization model, we provide numerical experiments for several test problems.