• Title/Summary/Keyword: new health technology

Search Result 1,283, Processing Time 0.025 seconds

Dudleya brittonii extract promotes survival rate and M2-like metabolic change in porcine 3D4/31 alveolar macrophages

  • Kim, Hyungkuen;Jeon, Eek Hyung;Park, Byung-Chul;Kim, Sung-Jo
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.32 no.11
    • /
    • pp.1789-1800
    • /
    • 2019
  • Objective: Although alveolar macrophages play a key role in the respiratory immunity of livestock, studies on the mechanism of differentiation and survival of alveolar macrophages are lacking. Therefore, we undertook to investigate changes in the lipid metabolism and survival rate, using 3D4/31 macrophages and Dudleya brittonii which has been used as a traditional asthma treatment. Methods: 3D4/31 macrophages were used as the in vitro porcine alveolar macrophages model. The cells were activated by exposure to phorbol 12-myristate 13-acetate (PMA). Dudleya brittonii extraction was performed with distilled water. For evaluating the cell survival rate, we performed the water-soluble tetrazolium salt cell viability assay and growth curve analysis. To confirm cell death, cell cycle and intracellular reactive oxygen species (ROS) levels were measured using flow cytometric analysis by applying fluorescence dye dichlorofluorescein diacetate and propidium iodide. Furthermore, we also evaluated cellular lipid accumulation with oil red O staining, and fatty acid synthesis related genes expression levels using quantitative polymerase chain reaction (qPCR) with SYBR green dye. Glycolysis, fatty acid oxidation, and tricarboxylic acid (TCA) cycle related gene expression levels were measured using qPCR after exposure to Dudleya brittonii extract (DB) for 12 h. Results: The ROS production and cell death were induced by PMA treatment, and exposure to DB reduced the PMA induced downregulation of cell survival. The PMA and DB treatments upregulated the lipid accumulation, with corresponding increase in the acetyl-CoA carboxylase alpha, fatty acid synthase mRNA expressions. DB-PMA co-treatment reduced the glycolysis genes expression, but increased the expressions of fatty acid oxidation and TCA cycle genes. Conclusion: This study provides new insights and directions for further research relating to the immunity of porcine respiratory system, by employing a model based on alveolar macrophages and natural materials.

A Review on the Practical Feasibility of Phrases 'Under the Instruction of Physicians or Dentists' Specified in the Definition on the Medical Service Technologist Etc Act: Focused on Radiological Technologist (의료기사 등에 관한 법률 중 '의사 또는 치과의사의 지도 아래' 문구의 타당성에 대한 고찰: 방사선사를 중심으로)

  • Joo, Young-Cheol;Lim, Cheong-Hwan;Lim, Woo-Taek;Hong, Dong-Hee;Jung, Hong-Ryang;Kim, Eun-Hye;Yoon, Yong-Su;Jung, Young-Jin;Choi, Ji-Won;Yoo, Se-Jong
    • Journal of radiological science and technology
    • /
    • v.44 no.5
    • /
    • pp.535-543
    • /
    • 2021
  • The purpose of this study is to investigate various opinions on changes and revisions in the Medical Technician Act, to compare the curriculum of radiological technologist and physicians or dentists, and to compare the definitions and scope of work of radiological technologist in Korea and abroad. From the information, The goal is to review whether the phrase 'guidance of a doctor or dentist' specified in the definition of the 'Act on Medical Technicians, etc.' is realistically appropriate. radiological technologist receive specialized college education on radioligical science & medical imaging. The training hours for radiolgical science student are greater than medical students. In addition, radiological technologists are continuously developing their competencies for new knowledge and skills through continuing education in clinical fields. In particular, radiological technologist are making steady research efforts to reduce patient exposure and improve medical image quality. As a result of this investigation, it is considered that the term "guided by a doctor or dentist" as currently defined in the 'Act on Medical Technicians, etc.' may need to be revised in consideration of the professionalism of the radiological technologist.

Low-Cost Flexible Strain Sensor Based on Thick CVD Graphene

  • Chen, Bailiang;Liu, Ying;Wang, Guishan;Cheng, Xianzhe;Liu, Guanjun;Qiu, Jing;Lv, Kehong
    • Nano
    • /
    • v.13 no.11
    • /
    • pp.1850126.1-1850126.10
    • /
    • 2018
  • Flexible strain sensors, as the core member of the family of smart electronic devices, along with reasonable sensing range and sensitivity plus low cost, have rose a huge consumer market and also immense interests in fundamental studies and technological applications, especially in the field of biomimetic robots movement detection and human health condition monitoring. In this paper, we propose a new flexible strain sensor based on thick CVD graphene film and its low-cost fabrication strategy by using the commercial adhesive tape as flexible substrate. The tensile tests in a strain range of ~30% were implemented, and a gage factor of 30 was achieved under high strain condition. The optical microscopic observation with different strains showed the evolution of cracks in graphene film. Together with commonly used platelet overlap theory and percolation network theory for sensor resistance modeling, we established an overlap destructive resistance model to analyze the sensing mechanism of our devices, which fitted the experimental data very well. The finding of difference of fitting parameters in small and large strain ranges revealed the multiple stage feature of graphene crack evolution. The resistance fallback phenomenon due to the viscoelasticity of flexible substrate was analyzed. Our flexible strain sensor with low cost and simple fabrication process exhibits great potential for commercial applications.

Feature Extraction for Bearing Prognostics based on Frequency Energy (베어링 잔존 수명 예측을 위한 주파수 에너지 기반 특징신호 추출)

  • Kim, Seokgoo;Choi, Joo-Ho;An, Dawn
    • The Journal of The Korea Institute of Intelligent Transport Systems
    • /
    • v.16 no.2
    • /
    • pp.128-139
    • /
    • 2017
  • Railway is one of the public transportation systems along with shipping and aviation. With the recent introduction of high speed train, its proportion is increasing rapidly, which results in the higher risk of catastrophic failures. The wheel bearing to support the train is one of the important components requiring higher reliability and safety in this aspect. Recently, many studies have been made under the name of prognostics and health management (PHM), for the purpose of fault diagnosis and failure prognosis of the bearing under operation. Among them, the most important step is to extract a feature that represents the fault status properly and is useful for accurate remaining life prediction. However, the conventional features have shown some limitations that make them less useful since they fluctuate over time even after the signal de-noising or do not show a distinct pattern of degradation which lack the monotonic trend over the cycles. In this study, a new method for feature extraction is proposed based on the observation of relative frequency energy shifting over the cycles, which is then converted into the feature using the information entropy. In order to demonstrate the method, traditional and new features are generated and compared using the bearing data named FEMTO which was provided by the FEMTO-ST institute for IEEE 2012 PHM Data Challenge competition.

Measuring the Environmental Attitudes for National Park Visitors : Application of New Environmental Paradigm (국립공원(國立公園) 방문객(訪問客)의 자연환경태도(自然環境態度) 측정(測定) : New Environmental Paradigm의 적용(適用))

  • Han, Sang-Yoel
    • Journal of Korean Society of Forest Science
    • /
    • v.89 no.5
    • /
    • pp.598-608
    • /
    • 2000
  • This study examined several characteristics such as the relationships between environmental attitudes and national park visitors' socio-economic characteristics, and between environmental attitudes and their travel motivations. Environmental attitude was measured using the modified New Environmental Paradigm(NEP) scale, where five response options existed(from strongly disagree to strongly agree). Data for this empirical analysis were obtained from 2,647 participants at six national parks-Sulaksan, Kayasan, Naeiangsan, Pookhansan, Taeanhaean, and Hanryohaesang. Results showed that most visitors gave a pro-NEP response ranging from neutral attitude to pro-environmentalism. Environmental attitudes correlated positively with education level, while, negatively with age. Environmental concern, also, generally correlated positively with 'rest' and 'health' motivators, while, negatively with 'socialization' and 'vacation' motivators. The findings of this study suggest that education is the most effective politic measure to lead pro-environmental concern for park visitors. And, given the nature of the relationship between environmental concern and visitors' motivation, park managers should be more careful handling with family and group visitors who have 'vacation' and 'socialization' motivators than 'rest' and 'health' motivators.

  • PDF

Entry into the Southeast Asian Energy Market from the Sales Promotion Viewpoint

  • Kwon, Ki-Tae;Lee, Woo-Sik;Kwon, Lee-Seung;Seong, Seung-Hwan;Kim, Young-Do;Kwon, Woo-Taeg
    • Journal of Distribution Science
    • /
    • v.15 no.10
    • /
    • pp.29-39
    • /
    • 2017
  • Purpose - The purpose of this study is to promote sales of the renewable energy industry and to advance into the Southeast Asian market. Research design, data, and methodology - This study is to develop a highly efficient food waste treatment system for Southeast Asian renewable energy industry. The radiation treatment method was applied for this purpose. Results - To investigate effects of ionization on removal of non-degradable organic matter, the results from gamma irradiation and co-digestion process was compared to those from a co-digestion process. Based on the BMP test results, food wastes were oxidized by hydroxyl radicals, and the specific methane yield was 366 mL CH4/g VS. Methane composition was 82%. A WAS/food wastes co-digestion was developed for the treated of non-degradable organic matter in food wastes. The average efficiency of non-degradable organic matter were 92.2% using the food waste co-digestion. Conclusions - Performance of gamma irradiation and co-digestion process was superior to that of a co-digestion process (10-20%). This implies that food wastes can be high efficient co-digested by the gamma irradiation. It is believed that it will be possible to enter the Southeast Asian energy industry as a strategic technology in the overseas energy recovery industry.

Development of an IAQ Index for Indoor Garden Based IoT Applications for Residents' Health Management (실내거주자 건강 관리를 위한 IoT기반 실내정원용 IAQ지수 개발)

  • Lee, Jeong-Hun;An, Sun-Min;Kwak, Min-Jung;Kim, Kwang Jin;Kim, Ho-Hyun
    • Journal of Environmental Health Sciences
    • /
    • v.44 no.5
    • /
    • pp.421-432
    • /
    • 2018
  • Objectives: In this study, we started to develop an indoor garden integrated IoT solution based on IAQ (indoor air quality) and interconnection with an environmental database for smart management of indoor gardens. The purpose of this study was to develop and apply an integrated solution for customized air purification from an indoor garden through big data analysis using IoT technology. Methods: An IoT-based IAQ monitoring system was established in three households within a new apartment building. Based on real-time and long-term data collected, $PM_{2.5}$, $CO_2$, temperature, and humidity changes were compared to those of indoor garden applications and the analyzed results were indexed. Results As a result of the installation, all three households had no results exceeding the standard for indoor air pollution on average $PM_{2.5}$ and $CO_2$ indices. In the case of indoor garden installation, the IAQ index increased to the "Good" section after the installation, and readings in the "Bad" section shown before the installation disappeared. The comfort index also did not dip into the "Uncomfortable" section, where it had been preinstallation, and significantly lowered the average score from "Uncomfortable for sensitive groups" to "Good". Overall, the IAQ composite index for the generation of installations decreased the "Good" interval, but "Bad" did not appear. Conclusions In this study on developing an integrated solution for IAQ based on IoT indoor gardens, big data was analyzed to determine IAQ and comfort indexes and an IAQ composite index. Through this process, it became understood that it is necessary to monitor IAQ based on IoT.

A Study on Health Check Solution using Indoor Air Purifier (실내 내장형 공기순환기를 이용한 헬스 체크 솔루션에 관한 연구)

  • Yang, Hee-Tak;Oh, Ji-Su;Lee, Keun-Ho
    • Journal of Internet of Things and Convergence
    • /
    • v.3 no.1
    • /
    • pp.25-31
    • /
    • 2017
  • In the future a future type new city and the latest apartment will be built, and the IoT technology will be constructed and combined in large numbers indoors of ordinary households. An air cleaner that makes people in it comfortable is built in, and the suction port that sucks in the air of the air purifier and the discharge port that discharges it are set up around the room and come out. However, this is impossible to adjust because there is only a central switch on / off. Also, consuming a lot of electricity so that many electricity charges are caused by huge electricity consumption will eventually be a waste of resources. This would like to be adjusted and driven through the fine dust detection device to the room built-in air purifier and that has provided a solution to save electricity. In addition, since it exists in and around the room, you can grasp the position of the person and connect to the home network to enhance the convenience. Also, through analysis of the air, we provide a health-check solution that checks the user's health and adjusts it appropriately.

Vibration Health Monitoring of Helicopter Transmission Systems at Westland Helicopter Ltd.

  • Kang, Chung-Shin;Choi, Sun-Woo;Ahn, Seok-Min;Horsey, M.W;Stuckey, M.J
    • International Journal of Aeronautical and Space Sciences
    • /
    • v.1 no.1
    • /
    • pp.48-61
    • /
    • 2000
  • Korea Aerospace Research Institute (KARI) have gained experience with Helicopter Vibration Health Monitoring (VHM) System technology with the help of UK GKN-WHL. GKN-WHL have had many years of experience with the research and development of vibration analysis techniques to improve the health monitoring of helicopter transmissions. This activity was targeted at transmission rig testing at first, but the techniques have been progressively developed where they are now used as a part of integrated Health and Usage Monitoring (HUM) systems on many types of in-service and new helicopters. The technique development process has been considerably aided by an ever expanding database of transmission monitoring experience from both the rig testing and aircraft operations. This experience covers a wide range of failure types from naturally occurring faults to crack propagation studies and covering a wide range of transmission configurations. Primarily based on accelerometer signals GKN-WHL's vibration analysis methods have also been applied to a variety of other sensor types. The transition from an experimental environment to operational VHM systems has been a lengthy process, there being a need to demonstrate technique reliability as well as effectiveness to both regulatory (Airworthiness Authority) and commercial organizations. Another important feature of this process has been the development of close relationships with a number of VHM system hardware and software suppliers. Such an experienced GKN-WHL provides various raw vibration data which was acquired from transmission ground test rig and allow KARI to develop it's own analysis program. KARI made a program and then analyzed the data to coma pre with the results of GKN-WHL. The KARI's results both time domain signals and statistical values show comparable to GKN's.

  • PDF

Development of Porous polyurethane Arterial-Venous Shunt by Thermal Phase Transition (온도 변화에 의한 상전이를 이용한 다공성 동정맥 누관의 개발)

  • Ryu, G.H.;Jeong, J.S.;Jeong, H.K.;Lee, H.K.;Lee, K.B.;Kim, J.;Min, B.G.;Lee, H.Y.
    • Proceedings of the KOSOMBE Conference
    • /
    • v.1997 no.05
    • /
    • pp.447-450
    • /
    • 1997
  • A new technique for the preparation of porous vascular prostheses was investigated. Polyurethane solution (10 to 14wt%) was injected into a mold. After freezing at low temperature $(0^{\circ}C\sim-40^{\circ}C)$, solvent was dissolved out with water at $0^{\circ}C$ to form porous tubes. The average pore size $(<10{\mu}m)$and pore occupation (10% to 51%) were easily changed by changing polyurethane concentration, freezing temperature, and freezing methods. This technique can give a proper pore size $(30\sim60{\mu}m)$ for tissue ingrowth, and suitable compliances for matching with arteries and veins. This method might give a desired compliant graft for artificial implantation with the presently valid medical polymers.

  • PDF