Proceedings of the KOSOMBE Conference (대한의용생체공학회:학술대회논문집)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Development of Porous polyurethane Arterial-Venous Shunt by Thermal Phase Transition

온도 변화에 의한 상전이를 이용한 다공성 동정맥 누관의 개발

  • Ryu, G.H. (Department of Medical Devices and Radiation Health, Korea Food and Drug Administration) ;
  • Jeong, J.S. (Department of Medical Engineering, College of Medicine, Seoul National University) ;
  • Jeong, H.K. (Department of Medical Devices and Radiation Health, Korea Food and Drug Administration) ;
  • Lee, H.K. (Department of Medical Devices and Radiation Health, Korea Food and Drug Administration) ;
  • Lee, K.B. (Biomedical and Science Center, Korean Institute of Science and Technology) ;
  • Kim, J. (Department of Medical Engineering, College of Medicine, Seoul National University) ;
  • Min, B.G. (Department of Medical Engineering, College of Medicine, Seoul National University) ;
  • Lee, H.Y. (Department of Medical Devices and Radiation Health, Korea Food and Drug Administration)
  • 유규하 (식품의약품 안전본부) ;
  • 정재승 (서울대학교 의과대학 의공학과) ;
  • 정희교 (식품의약품 안전본부) ;
  • 이해광 (식품의약품 안전본부) ;
  • 이규백 (한국과학기술원 의공학센터) ;
  • 김종원 (서울대학교 의과대학 의공학과) ;
  • 민병구 (서울대학교 의과대학 의공학과) ;
  • 이해룡 (식품의약품 안전본부)
  • Published : 1997.05.23
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Abstract

A new technique for the preparation of porous vascular prostheses was investigated. Polyurethane solution (10 to 14wt%) was injected into a mold. After freezing at low temperature $(0^{\circ}C\sim-40^{\circ}C)$, solvent was dissolved out with water at $0^{\circ}C$ to form porous tubes. The average pore size $(<10{\mu}m)$and pore occupation (10% to 51%) were easily changed by changing polyurethane concentration, freezing temperature, and freezing methods. This technique can give a proper pore size $(30\sim60{\mu}m)$ for tissue ingrowth, and suitable compliances for matching with arteries and veins. This method might give a desired compliant graft for artificial implantation with the presently valid medical polymers.

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