대한의용생체공학회:학술대회논문집 (Proceedings of the KOSOMBE Conference)

대한의용생체공학회 (The Korean Society of Medical and Biological Engineering)
권호 표지

온도 변화에 의한 상전이를 이용한 다공성 동정맥 누관의 개발

Development of Porous polyurethane Arterial-Venous Shunt by Thermal Phase Transition

  • 유규하 (식품의약품 안전본부) ;
  • 정재승 (서울대학교 의과대학 의공학과) ;
  • 정희교 (식품의약품 안전본부) ;
  • 이해광 (식품의약품 안전본부) ;
  • 이규백 (한국과학기술원 의공학센터) ;
  • 김종원 (서울대학교 의과대학 의공학과) ;
  • 민병구 (서울대학교 의과대학 의공학과) ;
  • 이해룡 (식품의약품 안전본부)
  • Ryu, G.H. (Department of Medical Devices and Radiation Health, Korea Food and Drug Administration) ;
  • Jeong, J.S. (Department of Medical Engineering, College of Medicine, Seoul National University) ;
  • Jeong, H.K. (Department of Medical Devices and Radiation Health, Korea Food and Drug Administration) ;
  • Lee, H.K. (Department of Medical Devices and Radiation Health, Korea Food and Drug Administration) ;
  • Lee, K.B. (Biomedical and Science Center, Korean Institute of Science and Technology) ;
  • Kim, J. (Department of Medical Engineering, College of Medicine, Seoul National University) ;
  • Min, B.G. (Department of Medical Engineering, College of Medicine, Seoul National University) ;
  • Lee, H.Y. (Department of Medical Devices and Radiation Health, Korea Food and Drug Administration)
  • 발행 : 1997.05.23
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초록

A new technique for the preparation of porous vascular prostheses was investigated. Polyurethane solution (10 to 14wt%) was injected into a mold. After freezing at low temperature $(0^{\circ}C\sim-40^{\circ}C)$, solvent was dissolved out with water at $0^{\circ}C$ to form porous tubes. The average pore size $(<10{\mu}m)$and pore occupation (10% to 51%) were easily changed by changing polyurethane concentration, freezing temperature, and freezing methods. This technique can give a proper pore size $(30\sim60{\mu}m)$ for tissue ingrowth, and suitable compliances for matching with arteries and veins. This method might give a desired compliant graft for artificial implantation with the presently valid medical polymers.

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