• 한국안광학회지
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• 제20권2호
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• pp.247-253
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• 2015

목적: 열화상카메라를 이용하여 정상안 군과 건성안 군의 검결막과 안구표면의 서모그래피를 객관적으로 알아보고자 하였다. 방법: 각막질환, 안외상, 누도이상자, 안과수술 병력 등 안구표면의 눈물막에 영향을 주는 질환이 없고 콘택트렌즈를 사용하지 않는 대학생 72명(144안)을 대상으로 하였다. TBUT, Schirmer I test, McMonnies test를 시행하여 정상안 군과 건성안 군으로 분류하고 열화상카메라(Cox CX series, Answer co., Korea)를 이용하여 안구표면과 검결막의 온도변화를 분석하였다. 결과: 정상안 군에서 안구표면 눈물막의 중심부, 코방향, 귀방향, 위, 아래방향에서 온도변화량은 $-0.13{\pm}0.08$, $-0.14{\pm}0.08$, $-0.12{\pm}0.08$, $-0.14{\pm}0.08$, $-0.10{\pm}0.09(^{\circ}C/sec)$이었고 건성안군에서는 $-0.17{\pm}0.08$, $-0.16{\pm}0.07$, $-0.16{\pm}0.08$, $-0.17{\pm}0.09$, $-0.15{\pm}0.08(^{\circ}C/sec)$로 중심부, 귀방향, 아래방향에서 유의성을 띠었다(p<0.05). 정상안 군으로 분류된 대상자의 중심부, 코방향, 귀방향의 검결막 온도는 $34.36{\pm}1.12$, $34.17{\pm}1.10$, $34.07{\pm}1.12^{\circ}C$였고, 건성안 군은 $34.17{\pm}1.10$, $33.43{\pm}0.97$, $33.51{\pm}1.06^{\circ}C$로 중심부에서 유의한 차이를 보였다(p=0.05). 결론: 건성안 군에서 정상안 군보다 안구표면의 온도 감소가 빠르게 나타났고 검결막의 온도도 낮은 것으로 관찰되었다. 열화상카메라를 활용한 안구표면의 온도변화는 눈물막의 안정성을 평가하는데 객관적이었으며 건성안 연구에 유용할 것으로 기대된다.

• Tuberculosis and Respiratory Diseases
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• 제59권5호
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• pp.497-503
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• 2005

연구배경 : 호흡기 바이러스 감염은 천식 및 만성폐쇄성폐질환의 악화와 관련이 있다고 알려져 있지만 국내의 자료는 충분치 않다. 방 법 : 급성 악화로 한림대학교 성심병원에 내원한 천식환자 20명과 COPD 환자 24명을 대상으로 비강 분비물과 객담에서 PCR과 배양을 통해 호흡기 바이러스를 검출하였다. rhinovirus, coronavirus는 PCR을, influenza A, B, RSV, parainfluenza virus는 배양을 통해 바이러스를 검출하였다. 결 과 : 천식의 급성 악화로 내원한 환자의 평균 연령은 45.4(${\pm}16.7$)세였고, 평소 $FEV_1/FVC$는 1.9/2.9L(65.5%)였다. 급성 악화 시 13예(13/20, 65%)에서 바이러스가 검출되었으며 rhinovirus 9예, coronavirus 2예, influenza A 2예, RSV 1예, parainfluenza virus가 1예였다. rhinovirus와 coronavirus, rhinovirus와 RSV가 동시에 검출된 예가 각각 1예가 있었다. COPD 환자의 평균 연령은 71.5(${\pm}8.4$)세였으며, 평소 $FEV_1/FVC$는 1.1/2.6L(42.3%)였고, 악화 시 14예(14/24, 58.3%)에서 바이러스가 검출되었다. rhinovirus 10예, coronavirus 3예, influenza A가 4예였으며 2예에서 rhinovirus와 coronavirus가 동시에 검출되었고, 1예에서 rhinovirus와 influenza A가 동시에 검출되었다. 결 론 : 호흡기 바이러스 감염은 국내에서도 천식 및 COPD 악화의 주요한 요인이 될 것으로 생각되며, 천식 및 COPD 환자의 악화에서 치료에 있어서 항생제 사용에 주의하여야 할 것으로 사료된다.

• 한방안이비인후피부과학회지
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• 제14권2호
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• pp.173-182
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• 2001

This Study is attempted in order to observe a clinical analysis from Constitution medical view point about allergic rhinitis. We studied 71 patients who had visited Dept. surgery, opthalmology & otolaryngology, col1ege of Oriental Medicine, Kyungsan University, Pohang, Korea and were treated by medications of Sasang Constitution and Constitution-Acupunture with allergic rhinitis from March 1, 2000 to February 28, 2001. The results were as follows: 1. The sex distribution was 71 males($69\%$), 22 femail($31\%$), In age distribution, the average was 29.6. The peak age was thirties($36.7\%$), teen-ager was $23.9\%,\;fortieth\;was\;15.5\%,\;under\;10\;years\;old\;was\;9.9\%,\;twenties\;was\;7\%,\;fifties\;was\;5.6\%,\;sixtisth\;was\;1.41\%$. 2. In the age of onset, thirties was $29.6\%$, teen-ager was $19.7\%$, twenties was $18.3\%$, under 10 years old and fortieth was $14.1\%$, fifties was $3.8\%$, sixtisth was $1.41\%$. 3 In monthly distribution. september was $25.8\%$, january was $14.1\%$, october was $11.3\%$. november and august was $8.5\%$, april was $7\%$, febuary and may were $5.6\%$, june, july. December were each $4.2\%$, In the distribution of season. the peak season was fall from september to November. 4. In the duration of the disease, 1-3 years was $26.8\%$, 3-5 years was $19.7\%$, 6 months - 1 year $16.9\%$, 5-10 years was $14.1\%$, under 6 months was $11.3\%$, over 10years and over 15 years were each $5.6\%$. 5. In the three main symptom, hydrorrhoea was $71.8\%$, nasal obstruction was $67.6\%$, sneezing was $64.8\%$. In others, fatique was $25.6\%$, headache was $14.1\%$, itching and cough was $11.3\%$, laryngopharyngeal discomfort and red eye were $4.2\%,\;infirmity\;was\;2.8\%$. 6. Patients whose families have allergic disease account for 26 cases($36.6\%$). 7. There was no past history in 37 cases($52.l\%$). In past history distribution, digestive tract disease was $12.7\%$, paranasal sinusitis was $8.5\%$, allergic dermatitis was $7\%$, common cold was $4.2\%$. otitis media, bronchitis, asthma, tonsillitis were $2.8\%$. 8. Sasang Constitution classification was Soyanggin in 52 cases($73.2\%$), Taeumgin in 12 cases($16.9\%$). Soumgin in 7 cases($9.9\%$). 9. In the duration of treatment, it was 1-2 weeks in 26 cases($36.6\%$), 2-4 weeks was $21.1\%$, under 1weeks was $14.1\%$, 4-6 weeks was $11.3\%$, 6-8 weeks was $8.5\%$, 8-10 weeks was $5.6\%$, over 10 weeks was $2.8\%$. 10. We had a follow-up survey the effect of treatment in the 60 cases. there was fair in 25 cases($41.7\%$), good in 21cases($35\%$), excellent in 3cases($5\%$)로 total rate of treatment was $81.7\%$. The case of no change was $16.7\%$, the case of poor was $1.6\%$.

• Investigative Magnetic Resonance Imaging
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• 제11권2호
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• pp.127-132
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• 2007

비강 및 부비동에 발생하는 신경내분비암종(neuroendocrine carcinoma)은 매우 드물고, 자기공명영상 소견에 대한 보고가 거의 없다. 이에 본 저자들은 비출혈을 주소로 내원한 62세 남자와 74세 남자에서 발생한 신경내분비암종의 2 증례에 대하여 전산화단층촬영과 자기공명영상의 소견을 중심으로 보고하고자 한다. 2예 모두 전산화단층촬영에서 비강과 부비동내에 비교적 크고 경계가 불분명한 종괴가 있었으며, 인접한 골 파괴를 동반하였다. 자기공명영상에서 종괴는 T1강조영상에서 등신호 강도를 보였고, T2강조영상에서는 등신호와 고신호가 섞여있는 양상을 보였으며, 조영 증강시 불균질한 조영 증강을 보였고 내부에는 괴사가 포함되어 있었다. 자기공명영상에서도 종괴에 인접한 골 파괴가 관찰되었다. 2예에서 모두 인접한 접형동내에 T1강조영상에서 고신호 강도를 보이는 점액낭 혹은 종양주변 낭성 부위가 관찰되었다. 2예 모두 전산화단층촬영과 자기공명영상에서 일반적인 비강과 부비동에 발생하는 악성 종양의 비특이적인 소견을 보였으나 종양 주변 낭성 부위의 의미에 대해서는 보다 많은 연구가 필요할 것으로 보인다.

• 한국환경과학회지
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• 제20권7호
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• pp.799-809
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• 2011

Objectives: This study is aimed at identifying the influential factors on the pulmonary function of ordinary residents in the surrounding areas of Yeosu Industrial Complex. Methods: The PFT (Pulmonary Function Test) was conducted on the target residents numbering 989 people (male 361, female 628). The exposed group (813 people) resided within the radius of 5km from Yeosu Industrial Complex and the control group (176 people) resided in the radius of more than 15 km from May 2007 to November 2007. The survey also took into account other factors including personal characteristics, life habits, respiratory diseases and allergic symptoms, medical histories, and the living environments of the residents in order to further identify influential factors on pulmonary function. Result: When comparing the PFT values of the exposure groups to the control group of the same city, values of the exposure groups were meaningfully lower with an %$FEV_1$ of 107.05% and %FVC of 100.28%. Conversely, the control group reported an %$FEV_1$ and %FVC of 107.26% and 102.85% respectively, indicating that ambient air pollutants reduce lung function. The odds ratio of asthma diagnosis history increased when a subjects residence was close to a heavily trafficked road, traffic amount was huge, a bed was used, and the family had less than four members. However the results were not statistically meaningful. The odds ratios of abnormal pulmonary function were statistically higher among those with asthma(OR=4.29, CI=1.75-10.56), wheezing (OR=2.59, CI=1.24-5.41), and nasal congestion (OR=2.87, CI=1.36-6.08) (p<0.01). The factors affecting $FEV_1$ were symptoms including asthma, passive smoking and allergic eye disease ($R^2$=0.049, p<0.001). For the FVC symptoms including asthma ($R^2$=0.014, p<0.001) were measured. The analysis showed that FVC decreased with increases in $O_3$ and CO(p<0.01). Furthermore, $FEV_1$ decreased with increases in $O_3$(p<0.01). Conclusions: These results will provide preliminary data for establishing responsive measures to protect the health of residents in industrial complexes from air pollution, and to develop lasting environmental health policies.

• Journal of Acupuncture Research
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• 제24권1호
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• pp.79-98
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• 2007

Objectives : The study of Traditional Korean medical therapy has recently become a popular academic field as proven to be an great alternative to the limitation of Western medical treatment. However, there has been little study examining the Quality of life to investigate the Effectiveness of Recent Traditional Korean Medical Therapy on Treating Allergic Rhinitis. Thus, this study aims to reveal the characteristics of Allergic Rhinitis patients, their clinical symptoms, and other accompanying diseases. Moreover, it attempts to investigate the sense of improvement and satisfaction from the Allergic Rhinitis patients treated with Traditional Korean Medical therapy by examining Quality of Life Questionnaires. Subject and Method : A total of 380 subjects that consists of allergic rhinitis patients and non patients were participated in this study. 330 allergic rhinitis patients were divided into two groups; the experimental group (230 subjects) was treated with Traditional Korean Medical therapy, and the control group (100 subjects) was not treated with any other therapy. Also, the normal control group (50 subjects) who had no symptoms of the allergic rhinitis was participated in this study as well. All the subjects were asked to answer to the questionaries that consist of two parts such as recalling the symptoms that they had 3 month ago, and describing the current symptoms that they had the present. The experimental group also was asked to answer the quality of life questionnaire before and after the therapy. Results: The results of investigating recent Traditional Korean therapy are as follows: 1. The reservoir rate of other disease was 39.0% in the control group and 34.8% in the experimental group. These were higher than the rate of the normal control (10.0%), which reveals the clinical characteristics of allergic rhinitis patients. 2. The symptoms of Allergic Rhinitis showed improvement after Traditional Korean medical therapy, which can be shown by its statistical significance. (p=.000<.001). 3. 97.0% of the Allergic Rhinitis patients treated with the Korean Therapy answered the improvement of symptom within 4 weeks, and 88.3% of the patients were satisfied with the Traditional Korean medical therapy. 4. The Nasal symptoms had prominently positive effect at the most as the symptoms significantly affect sleep disturbances, ocular symptoms, activity limitation, and emotional problems.

• 대한두경부종양학회지
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• 제21권2호
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• pp.115-120
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• 2005

Background and Objectives: Minor salivary gland tumors vary in their primary sites, histopathology and biological behavior. Therefore, various factors are considered in selecting the treatment modality and predicting the prognosis. We performed this study for the purpose of getting further understanding and more supporting ideas for the diagnosis and treatment of minor salivary gland tumor. Materials and Methods: A retrospective analysis of the patients with 52 cases of minor salivary gland tumor who were treated at the Hanyang University Hospital from 1996 to 2003 was performed. We analyzed demography, symptoms, histopathology, treatment and outcomes by the review of medical records. Results: Among 52 cases of minor salivary gland tumor, 46% were classified as benign and 54% were classified as malignant tumors. The most common benign tumor was pleomorphic adenoma. Adenoid cystic carcinoma(15/28) was the most common in malignant tumors. Eight patients were males and sixteen patients were females in benign tumors and 10 patients were males and 18 patients were females in malignant tumors. The most common site of benign tumor was the palate(17/22), whereas malignant tumors were most common in the nasal cavity and paranasal sinus(9/28). Asymptomatic mass was the most common symptom. According to the criteria given by the AJCC on staging, stage III and IV(21/28) were more common than stage I and 11(7/28). All benign tumors were treated with simple excision and had no recurrence. In malignant tumors, 25 patients underwent radical excisional operation and 13 patients of them had postoperative radiation therapy. Three of them were treated with additional chemotherapy. In whom treated with radical operation, 9 patients had recurrence. Three were recurred at the primary site with neck node metastasis, 3 were recurred at the primary site with lung metastasis, 1 was recurred at the primary site with neck node and lung metastasis, 1 was recurred only at neck node. Conclusion: In minor salivary gland tumor, malignant was more common than benign. Malignant tumor originated from minor salivary gland were more frequently diagnosed at advanced stage with high recurrence rate and distant metastasis. Early detection of the disease is needed to improve the prognosis of the patients with malignant tumors of the minor salivary glands.

• 생명과학회지
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• 제19권12호
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• pp.1847-1850
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• 2009

소 결핵은 만성적으로 서서히 진행 되어 쇠약해 지기 때문에 일반적으로 사후 검시 후에 확인 된다. 소결핵의 감염이 대부분 폐에서 발생하기 때문에 심한 경우에는 기침, 비루 및 호흡 곤란을 유발 한다. 본 고에서는 도축장에서 나온 사체의 심장, 간, 신장, 폐, 복수, 임파선 및 내장에서 얻은 시료를 분석한 것이다. 사체의 부검 검시도중 다양한 모양과 크기의 결핵 병변이 관찰 되었다. 백색 크림 색깔의 결핵은 화농성으로 임파선, 폐 및 장간막을 포함하여 흉막강에 퍼져 있었다. 폐와 임파선의 그램 염색과 Ziehl-Neelsen's acid-fast 염색 결과 강한 조직화학적 양성 반응을 나타내었다. Acid-fast에 염색된 유기체들이 현미경 검경에서 발견 되었다. 본 고에서는 의심원인체로 사료되는 Mycobacterium bovis의 조직학적 발견을 근거로 이에 의한 소결핵의 조직병리학적 소견을 보고하는 바이다.

• 한국의사학회지
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• 제17권2호
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• pp.111-127
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• 2004

This paper is mainly on the rsearch of the prescriptions of "Sanbeon-bang(刪 繁方)". For the research of prescription, investigated "Sanbeon-bang" from the side of symptoms of a disease, number of drugstuffs, table of contents, drugstuffs and acupuncture and moxibustion. With these investigation, made out a few tables, and with these tables made an attempt to understand the whole prescriptions of "Sanbeon-bang". "Sanbeon-bang" is of rich contents in internal medicine. Among internal medicine, related to Oro-Yukgeuk-Chilsang(五勞-六極-七傷) was most abundant. So we can guess "Sanbeon-bang" was a medical book specialized in exhaustion syndromes. It also deals with the Samcho-syndromes, as investigate from medical comments, has the perfect system of prescription in relative. From the investigation of the combination of drugstuffs, ascertained that, the number of simple prescription composed of one drugstuff was 38, combinational prescription composed of two drugstuffs was 9, minor prescription composed of three to five drugstuffs was 47, midum prescription composed of six to ten drugstuffs was 95, major prescription composed of eleven to twenty drugstuffs was 45, and mixed prescription composed over twenty drugstuffs was 1. Mentionable unique prescriptions in internal use were the forms of keeping in mouth. In external use they were fumigants, suppositories, powdered medicines, spraying the granular medication into the nasal cavity and eyedrops. And were abundant in soft extract(ointment) and plaster. In addition, there were the recordings of 18 types of cellulitis, types of incurable cellulitis and curing an illness by a charm. By the way, when comparing "Sanbeon-bang" with "Cheongeum-bang", all of which was quoted a lot in "Oedaebiyo-bang", "Cheongeum-bang" rather took medical comments of "Sanbeon-bang" than prescription. Although there were some prescriptons in "Sanbeon-bang" at the same category, "Cheongeum-bang" took another prescriptions which are more complexed than those of "Sanbeon-bang". In the same way, when comparing "Cheongeum-bang" with "Sonjinin-Cheongeum-bang(孫眞人千金方)", which didn't go through the correction of GyojeongUiseoguk of Bug-Song goverment, "Cheongeum-bang" often didn't take the prescriptions of "Sonjinin-Cheongeum-bang". Hence we can guess, "Cheongeumyo-bang" may have added a lot of prescriptions when undergoing the correction of of GyojeongUiseoguk. The total number of species of drugstuffs in "Sanbeon-bang" from the investigation was 284. The plant drugs were 208 species, the animal were 31 species, the minerals were 19 species and the other were 26 species. The prescriptions related to acupuncture and moxibustion in "Sanbeon-bang" were only moxibustional prescriptions. Which appeared one time per exhaustion and steaming of bone syndrome, Oro-Yukgeuk-Chilsang and Samcho syndrome. Appeared six times in muscle syndromes. But I cannot imagine the original form of acupuncture and moxibustion in "Sanbeon-bang" for deficiency of data.

• 한국환경보건학회지
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• 제37권3호
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• pp.182-192
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• 2011

Objectives: This study aims to identify the influential factors on the pulmonary function of targeted general residents in the areas surrounding Gwangyang Steel Mill. Methods: An PFT (Pulmonary Function Test) was conducted from May 2007 to November 2007 on 974 target residents (438 male, 536 female), including an exposed group (674 people) who resided within a radius of 5 km from Gwangyang Steel Mill in Gwangyang-si, Jeollanam-do and a control group (300 people) who resided outside a radius of 15 km. A survey related to personal characteristics, life habits, respiratory diseases and allergic symptoms, medical histories and living environments of the residents was also conducted to identify influential factors on pulmonary function. Results: As %$FEV_1$ and %FVC of the exposed group are 99.17% and 96.98%, respectively, and those of the control group are 105.47% and 101.91%, respectively, with the PFT values of the exposed group being lower than those of the control group (p<0.001), it turns out that the pollution in the industrial complex is likely to trigger a reduction in the pulmonary function of local residents. The odds ratio analysis result for asthma diagnosis history indicates that the odds ratios tend to be higher among surveyed residents who are living near above-average traffic volumes and are using beds, where it is statistically meaningful that especially the odds ratios are higher if the residences are closer to roads (p<0.01, CI=1.12-4.52). The factors that affect the FEV1 are identified as smoking, passive smoking, asthma diagnosis history, nasal congestion symptoms and allergic eye disease ($R^2$=0.154, p<0.001). The factors that affect the FVC are identified as smoking, passive smoking, asthma diagnosis history and allergic coryza ($R^2$=0.158, p<0.001). In addition, the analysis result for the relevance of air pollution levels to pulmonary function ($FEV_1$, FVC) shows that FEV1 and FVC tend to decrease as the concentration of $O_3$ increases. Conclusions: We believe that this study may provide preliminary data for the development of preventive measures for health effects on the residents and environmental health control measures for environmental pollution in the industrial complex area.