• Journal of Yeungnam Medical Science
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• 제39권3호
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• pp.181-189
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• 2022

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative condition characterized by loss of motor neurons, resulting in motor weakness of the limbs and/or bulbar muscles. Pain is a prevalent but neglected symptom of ALS, and it has a significant negative impact on the quality of life of patients and their caregivers. This review outlines the epidemiology, clinical characteristics, underlying mechanisms, and management strategies of pain in ALS to improve clinical practice and patient outcomes related to pain. Pain is a prevalent symptom among patients with ALS, with a variable reported prevalence. It may occur at any stage of the disease and can involve any part of the body without a specific pattern. Primary pain includes neuropathic pain and pain from spasticity or cramps, while secondary pain is mainly nociceptive, occurring with the progression of muscle weakness and atrophy, prolonged immobility causing degenerative changes in joints and connective tissue, and long-term home mechanical ventilation. Prior to treatment, the exact patterns and causes of pain must first be identified, and the treatment should be tailored to each patient. Treatment options can be classified into pharmacological treatments, including nonsteroidal anti-inflammatory drugs, antiepileptic drugs, drugs for cramps or spasticity, and opioid; and nonpharmacological treatments, including positioning, splints, joint injections, and physical therapy. The development of standardized and specific assessment tools for pain-specific to ALS is required, as are further studies on treatments to reduce pain, diminish suffering, and improve the quality of life of patients with ALS.

• 한국의류학회지
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• 제45권2호
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• pp.346-355
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• 2021

Art strategies have been addressing the problem of volume growth caused by changes in the distribution environment of luxury brands. Art is a universal language that transcends borders and communicates across cultures, therefore, artification acts as a strategy for the globalization of luxury brands. This study aims to study how contemporary luxury brands communicate their artifacts strategically through branded products via artification. As a research method, a literature review and case studies were combined. The cases of artification range from the 2000s to the present, and the top 100 brands in the luxury category of Millward Brown were selected. Drawing on the characteristics of artification defined in this study we analyzed the cases of articulation of luxury brands. As a result, first, appropriation of art in the product frame is carried out by borrowing ideas from renowned works or artists. Second, as an experimental attempt, it is effective to associate the international reputation of an artist with a product through a reinterpretation of the product. Third, as an artistic creation for the brand narrative, luxury products are sublimated into artwork and idealized.

• 수완나부미
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• 제14권2호
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• pp.233-249
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• 2022

Hizb ut-Tahrir (HT) is an Islamic social movement that struggles to change the existing political system to the Islamic system. HT argues that all problems in the Muslim world are rooted in adopting secular thought and ideology and the separation between Islam and the state. Hence, HT works to persuade Muslims to abandon that way of life and only apply Islam as the country's only ideology and constitution. HT has spread this narrative since it started in 1953 in Jordan. With this ideological and political attitude, many countries consider HT a threat to their political and community life, suppressing this movement by arresting members and banning the group to reduce or end HT activities in these countries. The Indonesian government has also carried out this repressive policy to limit the influence of Indonesian HTI since 2017. This paper aims to discuss the strategy of Hizb ut-Tahrir to continue its political activities Indonesia after being dissolved by the Indonesian government in 2017. This article used content analysis method to interpret the data collected from interview and documents from Hizb ut-Tahrir. Responding to state repression, HTI sought other methods of action by changing the place of resistance or activities, and by changing its identity.

• 영어영문학
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• 제57권3호
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• pp.457-472
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• 2011

The word "subject," like its apparent antonym "agent" is ambiguous. By "speaking subject" I intend both meanings: the spoken about, and the speaker, and the spoken about, in more or less that order. The paper contrasts the way women are spoken about in the 19^th Century debate over the role of women between John Ruskin and John Mill, and then in literary criticism of feminists nearer our own time, Kate Millet and Elizabeth Langland. I then move on to women as speaking subjects, first in the form of an imaginary speaking subject created by a male speaker, Charles Dickens channeling the confessional journal of Esther Summerson in Bleak House. The comparison with Elizabeth Gaskell, a genuine speaking subject, is highly instructive. I draw attention to symmetrical, in the sense of opposite, narrative strategies. Where Dickens begins in journalese, with a gritty, realistic opening that only gradually reveals a Cinderella in the ashes, Gaskell begins with a nursery rhyme, in an actual nursery, but goes on to reveal some rather sordid economic facts. Where Dickens creates a ventriloquist's doll, Gaskell succeeds in creating recognizable, if not always admirable, female voices. I conclude that just as the novel may be read as a real utterance in a real conversation, it is also possible to read the true emergence of women novelists in the 19^th Century as nothing more and nothing less than the creation of the first truly womanly words about women: women as speaking subjects in both senses of the word.

• Journal of Trauma and Injury
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• 제36권3호
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• pp.165-171
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• 2023

Trauma remains a significant healthcare burden, causing over five million yearly fatalities. Notably, the liver is a frequently injured solid organ in abdominal trauma, especially in patients under 40 years. It becomes even more critical given that uncontrolled hemorrhage linked to liver trauma can have mortality rates ranging from 10% to 50%. Liver injuries, mainly resulting from blunt trauma such as motor vehicle accidents, are traditionally classified using the American Association for the Surgery of Trauma grading scale. However, recent developments have introduced the World Society of Emergency Surgery classification, which considers the patient's physiological status. The diagnostic approach often involves multiphase computed tomography (CT). Still, newer methods like split-bolus single-pass CT and contrast-enhanced ultrasound (CEUS) aim to reduce radiation exposure. Concerning management, nonoperative strategies have emerged as the gold standard, especially for hemodynamically stable patients. Incorporating angiography with embolization has also been beneficial, with success rates reported between 80% and 97%. However, it is essential to identify the specific source of bleeding for effective embolization. Given the severity of liver trauma and its potential complications, innovations in diagnostic and therapeutic approaches have been pivotal. While CT remains a primary diagnostic tool, methods like CEUS offer safer alternatives. Moreover, nonoperative management, especially when combined with angiography and embolization, has demonstrated notable success. Still, the healthcare community must remain vigilant to complications and continuously seek improvements in trauma care.

• Journal of Yeungnam Medical Science
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• 제41권2호
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• pp.61-73
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• 2024

Acute kidney ischemia-reperfusion (IR) injury is a life-threatening condition that predisposes individuals to chronic kidney disease. Since the kidney is one of the most energy-demanding organs in the human body and mitochondria are the powerhouse of cells, mitochondrial dysfunction plays a central role in the pathogenesis of IR-induced acute kidney injury. Mitochondrial dysfunction causes a reduction in adenosine triphosphate production, loss of mitochondrial dynamics (represented by persistent fragmentation), and impaired mitophagy. Furthermore, the pathological accumulation of succinate resulting from fumarate reduction under oxygen deprivation (ischemia) in the reverse flux of the Krebs cycle can eventually lead to a burst of reactive oxygen species driven by reverse electron transfer during the reperfusion phase. Accumulating evidence indicates that improving mitochondrial function, biogenesis, and dynamics, and normalizing metabolic reprogramming within the mitochondria have the potential to preserve kidney function during IR injury and prevent progression to chronic kidney disease. In this review, we summarize recent advances in understanding the detrimental role of metabolic reprogramming and mitochondrial dysfunction in IR injury and explore potential therapeutic strategies for treating kidney IR injury.

• 대중서사연구
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• 제26권4호
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• pp.9-41
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• 2020

이문열의 동명의 단편소설을 영화화한 박종원의 데뷔작 <구로아리랑>은 1987년 민주화의 흐름을 타고 노동자의 관점에서 노동 투쟁을 다룬 최초의 제도권 노동영화이자, 그동안 스크린이 외면해 온 여성 노동자의 재현이라는 측면에서 선구적인 작품이다. 박종원은 노동 문제와 관련하여 당시에 여전히 굳건하게 서 있던 레드컴플렉스의 장벽을 뚫고 사회의 이념 지형의 중추를 이루는 중산층을 설득하고자 하며, 진보의 메시지를 중산층 대중이 받아들일 수 있는 형태로 전달하기 위해 계급적 적대나 투쟁이 아니라 보편적 인간성과 윤리와 결부된 문제로 치환하는 감성에 의지한다. 박종원은 이러한 감성을 '상식적인 일반인의 감각'이라고 부르며 그 보편성과 객관성을 강조한다. 이 연구는 <구로아리랑>에서 노동 문제를 제도권 상업 영화 속에서 대중이 받아들일 수 있는 형태로 다루기 위해 어떤 전략을 취하는지, 또 그러한 전략에 반영된 '상식적인 일반인의 감각'이 어떤 이데올로기적 함의를 지니는지를 비판적으로 고찰해보고자 한다. 이를 위해 본론의 첫 번째 장에서는 영화가 원작 소설의 아이러니를 해체하고 인물의 구도를 순수한 선인과 악인의 대립으로 재설정하여 선인이 희생양이 되는 멜로드라마적 구성을 만들어낸다는 것을 밝힌다. 이로써 관객에게 노동자들이 겪는 비극에 강한 정서적 공감과 연대의식을 불러일으키려 한다. 두 번째 장에서는 영화의 다양한 장면과 에피소드들이 동정과 애도의 모티브로 수렴되며, 이는 대부분 당시 커다란 대중적 반향을 일으킨 문화적, 현실적 경험과 사건을 토대로 하고 있다는 점을 보일 것이다. 특히 영화의 마지막 결정적 장면에서는 87년 6월 항쟁의 기억이 강력하게 소환된다. 이에 따라 <구로아리랑>은 검증된 동정과 애도의 패치워크와 같은 양상을 보인다. 세 번째 장은 노동자들이 결정적인 투쟁에 나서는 대목에서 임금에 대한 요구를 스스로 뒤로 돌리고 인간적 신뢰와 대우의 문제를 앞세운다는 영화의 설정이 가지는 함의를 검토한다. 그것은 노동 문제의 정치적 차원을 제거하고 이를 윤리적 문제로 환원함으로써 모두가 인정할 수밖에 없는 보편적인 가치와 정서에 호소한다. 그러나 문제의 층위를 계급적 이해 관계의 충돌을 피해 순수한 인간성의 차원으로 옮기는 과정에서 노동자는 한 편으로는 깊이 동정할 만한 수동적 희생자의 위치에 떨어지고, 다른 한 편으로는 현실에 초연한 지사적 태도와 자제심을 갖춘 투사로 이상화된다. 영화는 이로써 현실적 설득력을 상실하며 영화 자체로서의 서사적 개연성도 약화된다. 중산층과의 연대를 환기하는 87년 항쟁의 기억은 영화 속에 조화롭게 통합되지 못하고 패치워크적 전체의 일부로 남는다.

• 한국콘텐츠학회논문지
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• 제15권7호
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• pp.157-169
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• 2015

본 연구는 역사적 소통 공간으로써 역사 영화에 주목하여 광주 민주화 운동을 주요 주제로 다룬 2000년대 영화 <오래된 정원>, <화려한 휴가>, <26년> 세 편을 중심으로 미디어가 재현하는 역사적 담론이 무엇인지 서사분석을 실시하였다. 분석결과, 스토리의 통합체 분석은 '균형-불균형-균형'의 시퀀스를 공통적으로 나타내면서 사회적 불균형을 개인과 가족이라는 개인적 측면으로 안정화 하여 사회구조적 문제를 감추는 정치성을 파악할 수 있었다. 또한 인물 관계의 계열체 분석은 여성 주인공의 적극적인 현실 참여 전략, 극중 살아남은 자들을 통한 역사의 연속성 강조 전략 등을 통해 광주 민주화 운동의 역사적 진실과 의미를 공론화시키는 것을 발견할 수 있었다. 결국 광주 민주화 운동의 재현은 사회구조적 문제의 해결 부재나 러브 스토리 배치를 통해 역사적 의미의 약화라는 한계에도 불구하고, 광주 민주화 운동을 과거의 역사로 남기지 않고 현재적 차원으로 끌어올려 공적 영역으로 소환시키는 가능성을 나타냈다. 따라서 역사 영화가 우리의 역사를 끊임없이 현재화하고 우리 사회에 여전히 남아있는 사회구조적 문제를 환기시킨다는 측면에서 역사적 소통 공간으로써 의의가 존재한다.