In order to study the effects of Goosunsan known clinically for their effects of treatment for cough and asthmas the study was carried out to investigate the effect of Goosunsan extract on the contractile force of the isolated guinea pig's vaviovs kinds smooth muscles and elucidate its mechanism The result were obtained as follows: 1. The isolated trachea & ileum smooth muscles of guinea pig was suspended in the organ bath with oxygenated kreb's Henselsite bicarbonate buffer solution at $37^{\circ}C$, and the developed tension by the drug was recorded with Isometric transducer (nacro F-60). The resting tension was approximately 0.5g. 2. The isolated trachea & ileum smooth muscles of guinea pig was remakably relaxed by the administration of Goosunsan. 3. The contractile response of the trachea smooth muscle of the isolated guinea pig to histamine 10-4 M was remakably by Goosunsan extract. 4. The contractile response of the ileum smooth muscle of the isolated guinea pig to histamine 10-4 M was remakably by Goosunsan extract. 5. The contractile response of the trachea smooth muscle of the isolated guinea pig to acetylcholine 10-4 M was remakably by Goosunsan extract. 6. The contractile response of the ileum smooth muscle of the isolated guinea pig to acetylcholine 10-4 M was remakably by Goosunsan. 7. The contractile response of the trachea smooth muscle of the isolated guinea pig to 5-hydroxytryptamine 10-4 M was remakably by Goosunsan. 8. The contractile response of the ileum smooth muscle of the isolated guinea pig to 5-hydroxytryptamine 10-4 M was remakably by Goosunsan.
Purpose: The purpose of this study was to examine the effects of daily exercise before steroid treatment on mass, the type I and II fiber cross-sectional area, and myofibrillar protein content of hindlimb muscles in a rat model. Method: Adult male Sprague-Dawley rats were randomly assigned to one of three groups: a control group(n=10) that had a normal saline injection for 7days, a steroid group(n=10) that had a steroid injection for 7days, and an exercise-steroid group(n=10) that ran on the treadmill for 7days before a steroid treatment. Body weight and food intake were measured every day. At 15 days all rats were anesthetized and the soleus, plantaris and gastrocnemius muscles were dissected. Result: The exercise-steroid group showed significant increases as compared with the steroid group in body weight, muscle weight of the soleus and gastrocnemius, type II muscle fiber cross-sectional area of plantaris, and myofibrillar protein content of the soleus, plantaris, and gastrocnemius. As compared with the control group, the steroid group showed significant decreases in body weight and diet intake, muscle weight, the type II fiber cross-sectional area and myofibrillar protein content of the soleus, plantaris, and gastrocnemius muscles. Conclusion: Daily exercise before steroid treatment attenuates hindlimb muscle atrophy, with type II muscle changes more apparent than type I muscle changes.
Purpose: Therapeutic climbing has become very popular today, with it being reported as a new method for preventing and treating orthopedic trauma to the shoulder joint. However, objective studies on its effects on the musculoskeletal system are still lacking. The objective of the present study was to investigate the effects of wall inclination during therapeutic climbing on the muscle activity around the shoulder joint. Methods: In this study, the participants performed movements at three different inclination angles of $0^{\circ}$, $+15^{\circ}$, and $-15^{\circ}$. sEMG was performed to measure the activities of five different muscles around the shoulder joint (biceps brachii, serratus anterior, upper trapezius, middle trapezius, and lower trapezius muscles). Results: Biceps brachii muscle showed a significant increase at $-15^{\circ}$, as compared to $0^{\circ}$ (p<0.01), and the serratus anterior also showed a significant increase at $-15^{\circ}$, as compared to $0^{\circ}$ (p<0.05). Moreover, the middle and lower trapezius muscles also showed a significant increase at $-15^{\circ}$, as compared to $0^{\circ}$ (p<0.001). Compared to $0^{\circ}$, all muscles showed decreased values at $15^{\circ}$, but the differences were not statistically significant (p>0.05). Conclusion: Therapeutic climbing may be a new therapeutic approach that can increase muscle strength and coordination in the sensory nervous system, since it can be used as a tool that promotes active movement by altering wall inclination and causing the user to generate movements according to the existing situation.
The objectives of the study were twofole: (1) to investigate effects of rhythmic contraction and sustained contraction methods on recovery rate of isometric endurance capacity and (2) to compare aptterns of muscle recruitment of both arms observed during each contraction period. In the experiment, each of two subjects performed five successive rhythmic or sustained isometric contractions at 50% MVC with both arms to the point of fatigue, which was the failure to maintain the required tension. In making the contractions, the subjects stood erect with upper arms held at an angle of approximately 90 .deg. to the forearm. The interval between the successive contractions was kept constant at 3, 7, 20, or 40 minutes. Regardless of the contraction methods, the recovery rate was least at the shortest interval and was highest at the longest interval. However, a statistical analysis showed that the recovery rates for the rhythmic contractions were significantly lower than those for the sustained contractions throughout 4 different intervals. Furthermore, as the frequency of the rhythmic contractions per min, increased 4 to 6 times, the recovery rate of isometric endurance capacity decreased. From an EMG anglysis, recruitment pattern of the muscules of both arms was found to be common between two different contraction methods. The biceps muxcles of the upper arms played a major role in exerting 50% MVC, while the brachioradialis muscles of the forearms acted as synergists. As the contraction proceeded, the role of the biceps muscles as a prime mover lessened due to the fatigue. Then, the brachioradialis muscles exerted more strength to sustain 50% MVC. The implications of these finding were discussed.
Kim, Jae-Cheol;Yi, Chung-Hwi;Kwon, Oh-Yun;Oh, Duck-Won;Jeon, Hye-Seon
Journal of the Ergonomics Society of Korea
/
v.26
no.4
/
pp.25-31
/
2007
The purpose of this study was to investigate the strength and endurance of the deep neck flexor muscles in individuals with work-related neck pain. Subjects consisted of two groups: twenty industrial workers with neck pain and twenty age-matched healthy subjects. To evaluate the strength and endurance of deep cervical flexors, maximum voluntary contractile strength (MVCS) and a sustained time at sub-maximal voluntary contractile strength (SMVCS) (80% and 50% of MVCS) were measured using a pressure biofeedback unit and a stop watch in supine. The MVCS of deep neck flexor muscles was 29.67${\pm}$4.56 in neck pain group and 54.27${\pm}$6.78㎜Hg in normal group. The sustained time at 80% SMVCS was 12.42${\pm}$2.64 seconds and 55.12${\pm}$12.76 seconds in the groups with and without neck pain. The sustained time at 50% SMVCS was 25.40±5.88 seconds and 109.70${\pm}$31.50 seconds in the groups with and without neck pain. The difference of the lower jaw position was 16.75${\pm}$3.57㎜ and 23.03${\pm}$2.51㎜. The MVCS, endurance at the two sub-maximal levels and the difference of the lower jaw position were significantly greater in the group without neck pain than with neck pain (p$<$0.05). The findings indicate that the maximal strength and endurance of the deep neck flexors were decreased in the workers with neck pain compared to those without neck pain. Therefore, it is necessary to include strengthening and endurance exercises of the deep neck flexor muscles in therapeutic program of work-related musculoskeletal disorders involving neck pain.
Kim, Ri Na;Lee, Jin-Hyuck;Hong, Seok Ha;Jeon, Jin Ho;Jeong, Woong Kyo
Clinics in Shoulder and Elbow
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v.21
no.3
/
pp.145-150
/
2018
Background: This study evaluated the shoulder girdle muscle characteristics of elite archery athletes and provides suggestions for archery training programs. Methods: This study enrolled 15 cases of high level archery athletes (7 males, 8 females) and 30 cases of (15 males, 15 females) sex, age-matched, healthy, non-athletic individuals. We measured peak torques of flexion (FL), extension (EX), abduction (ABD), adduction (ADD), external rotation (ER) and internal rotation (IR) of both shoulders at an angular velocity of $30^{\circ}/sec$, $60^{\circ}/sec$, and $180^{\circ}/sec$. The peak torques and peak torque ratios of FL/EX, ABD/ADD, and ER/IR of the two groups were compared. Results: The archer group had a greater peak torque of IR and ADD, but only in the left shoulder (p<0.05). In the same group, both shoulders had greater peak torque of EX and lower peak torque of FL. The peak torque ratios of FL/EX of both shoulders were significantly lower in the archer group at all three angular velocities (p<0.05). The peak torque ratios of ABD/ADD were significantly greater in only the left shoulder of the archer group (p<0.05). Conclusions: The prominent characteristics of the shoulder girdle muscles of an elite archer are stronger adductor muscles of the bow shoulder and stronger extensors of both shoulders, as compared to healthy, non-athletic individuals. These muscle groups of the shoulder probably contribute a major role in maintaining the accuracy and stability during archery shooting. Hence, a training program that selectively enhances the adductor and extensor muscles could prove helpful in enhancing the archery skills of the athlete.
Kang, Sun Moon;Kang, Geunho;Seong, Pilnam;Kim, Youngchun;Park, Beomyoung;Cho, Soohyun
Food Science of Animal Resources
/
v.33
no.6
/
pp.752-756
/
2013
This study was carried out to investigate the effect of cooking condition on the water-soluble flavor precursors relevant to postmortem glycogen metabolisms in various beef muscles from Hanwoo (Korean cattle). The loins, striploins, top rounds, and eye of rounds from 40-mon-old heifers were cooked in either with $100^{\circ}C$ water bath (wet-cooking) or $180^{\circ}C$ household electric oven (dry-cooking) until attained to about $80^{\circ}C$ of internal temperature before the measurements of amounts of macroglycogen, proglycogen, free glucose, and lactate. The macroglycogen and proglycogen contents were not significant differences in all beef muscles between the wet-cooking and dry-cooking treatments. Regardless of cooking condition, the both loin and top round had higher (p<0.05) two types of glycogen than the eye of round. The free glucose and lactate contents presented higher trends in the dry-cooking treatment compared with the wet-cooking treatment. The wet-cooked top round had higher (p<0.05) free glucose than the wet-cooked eye of round. Moreover, the top round contained the highest lactate content regardless of cooking condition. Consequently, it is considered that the dry-cooking treatment would be more beneficial to the flavor of cooked beef muscles than the wet-cooking treatment.
Fish muscles are classified into white and red muscles, and the chemical composition of the two fish muscles have many differences. Few reports have assessed the health-promoting functions of white fish muscle proteins (WFP) and red fish muscle proteins (RFP). We therefore evaluated the mechanisms underlying the alteration of lipid profiles and cholesterol metabolism following the intake of WFP prepared from cod and RFP prepared from light muscles of tuna. Male Wistar rats were divided into six dietary groups: casein (23%), WFP (23%), and RFP (23%), with or without 0.5% cholesterol and 0.1% sodium cholate. Compared to the WFP-containing diet, the RFP-containing diet supplemented with cholesterol and sodium cholate significantly increased serum and liver cholesterol contents. However, in the RFP groups, an alteration in cholesterol metabolism including an increased tendency to excrete fecal sterols and hepatic cholesterol $7{\alpha}$-hydroxylase was related to the reduction of hepatic cholesterol contents. This phenomenon might be related to the tendency of an increased food intake in RFP-containing diets. These results highlight the differential effects of WFP and RFP on serum and liver lipid profiles of Wistar rats fed non-cholesterol- or cholesterol-containing diets under no fasting condition.
Recently, interest in monitoring health and sports is growing because of the emphasis on wellness, which is accelerating the development and commercialization of smart clothing for biosignal monitoring. In addition to exerciseeffect monitoring clothing that tracks heart rate and respiration, recently developed clothing makes it possible to monitor muscle balance using electromyogram (EMG). The electrode for EMG have to attached to an accurate location in order to obtain high-quality signals in surface EMG measurement. Therefore, this study develops monitoring clothing suitable for different types of human bodies and aims to extract suitable range of EMG according to movements in order to develop self-fitness monitoring clothing based on EMG measurement. This study identified and attached electrodes on six upper muscles and two lower muscles of ten males in their 20s. After selecting six main motions that create a load on muscles, the 8-ch wireless EMG system was used to measure amplitude value, noise, SNR and SNR (dB) in each part and statistical analysis was conducted using SPSS 20.0. As a result, the suitable range for EMG measurement to apply to clothing was identified as four parts in musculus pectoralis major; three parts in muscle rectus abdominis, two parts each in shoulder muscles, backbone erector, biceps brachii, triceps brachii, and musculus biceps femoris; and four part in quadriceps muscle of thigh. This was depicted diagrammatically on clothing, and the EMG-monitoring sensing locations were presented for development of self-fitness monitoring.
Heu, Min Soo;Choi, Byeong Dae;Kim, Ki Hyun;Kang, Sang In;Kim, Yong Jung;Kim, Jin-Soo
Korean Journal of Fisheries and Aquatic Sciences
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v.48
no.1
/
pp.16-25
/
2015
This study compared the food quality of salmonid fishes according to the species, country of origin, and separated part, such as fillet and frame. The proximate composition of chum salmon from Norway (CS-N) was 74.4% moisture, 19.5% crude protein, 4.2% crude lipid, and 1.2% ash. These values were within roughly 1% for the other salmon species. There was no significant difference (at P<0.05) in the Hunter a value of salmon muscle according to sepatated parts. However, there was a significant difference (P<0.05) in Hunter a value of salmon muscle according to the species and country of origin. There were significant differences in odor intensity and hardness of the salmon according to the species. The major free amino acid in all of the salmon muscles was anserine, which ranged from 61.3 to 73.0%. The taste value was the highest for salmon imported from Alaska (CS-A), followed by pink salmon, CS-N, and muscle separated from the frame (AS-C). In the taste value of all salmon muscles, the major amino acid was glutamic acid. The total amino acid content of salmon muscles ranged from 18.36 to 19.64 g/100 g, and the major amino acids were glutamic acid and aspartic acid. There were differences in the mineral contents, including Ca, P, K, and Fe, and fatty acid composition of salmon muscle according to species.
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