Effects of GooSunSan(九仙散) Extract on the Contraction of Isolated guinea pig's various kinds smooth muscles

구선산(九仙散)이 GUINEA PIG의 각종(各種) 평활근(平滑筋)에 미치는 영향(影響)

  • Lyu, Dong-Soo (Department of Oriental Medicine Graduate School Won Kwang University) ;
  • Han, Sang-Whan (Department of Oriental Medicine Graduate School Won Kwang University)
  • Published : 1991.01.01

Abstract

In order to study the effects of Goosunsan known clinically for their effects of treatment for cough and asthmas the study was carried out to investigate the effect of Goosunsan extract on the contractile force of the isolated guinea pig's vaviovs kinds smooth muscles and elucidate its mechanism The result were obtained as follows: 1. The isolated trachea & ileum smooth muscles of guinea pig was suspended in the organ bath with oxygenated kreb's Henselsite bicarbonate buffer solution at $37^{\circ}C$, and the developed tension by the drug was recorded with Isometric transducer (nacro F-60). The resting tension was approximately 0.5g. 2. The isolated trachea & ileum smooth muscles of guinea pig was remakably relaxed by the administration of Goosunsan. 3. The contractile response of the trachea smooth muscle of the isolated guinea pig to histamine 10-4 M was remakably by Goosunsan extract. 4. The contractile response of the ileum smooth muscle of the isolated guinea pig to histamine 10-4 M was remakably by Goosunsan extract. 5. The contractile response of the trachea smooth muscle of the isolated guinea pig to acetylcholine 10-4 M was remakably by Goosunsan extract. 6. The contractile response of the ileum smooth muscle of the isolated guinea pig to acetylcholine 10-4 M was remakably by Goosunsan. 7. The contractile response of the trachea smooth muscle of the isolated guinea pig to 5-hydroxytryptamine 10-4 M was remakably by Goosunsan. 8. The contractile response of the ileum smooth muscle of the isolated guinea pig to 5-hydroxytryptamine 10-4 M was remakably by Goosunsan.

Keywords

References

  1. 衛生寶鑑 羅天益
  2. 醫學綱目 v.26 樓全英
  3. 醫學正傳 虞搏
  4. 東醫寶鑑 許浚
  5. 醫方類聚 v.6分冊 金禮夢
  6. 景岳全書 張介賓
  7. 丹溪心法附餘 方廣
  8. 方劑學 上海中醫學院
  9. 古今圖書集成醫部全錄 v.6分冊 陳夢雷
  10. 歷代名醫良方註釋 再小峰
  11. 實用中醫方劑學 游士勳;張錦淸
  12. 古今醫方 楊蘊祥;劉翠榮
  13. 古今醫統秘方大全 v.6 徐春甫
  14. 簡明方劑辭典 康克明;包明蕙
  15. 診療要鑑 金定濟
  16. 漢方秘錄 李璟模
  17. 東醫臨床內科 姜允皓
  18. 衛生易簡方 胡熒
  19. 醫學入門 v.外集卷 2 李梃
  20. 類症治裁 林佩琴
  21. 醫宗金鑑 吳謙
  22. 奇效良方 方賢
  23. 濟衆新編 康明吉
  24. 醫宗損益 v.上 黃道淵
  25. 六科準繩 王肯堂
  26. 皇漢醫學最書
  27. 劉河間三六書 劉河間
  28. 萬病醫學顧問 陸靑節
  29. 東醫小兒科學 丁奎萬
  30. 證治彙補 李用粹
  31. 沈氏尊生書 沈勳?
  32. 內科學 v.下 李文鎬;許仁穆;金鍾勳
  33. 石唐韓醫學 韓南洙
  34. 藥理學講義 李宇柱
  35. 半瓜丸이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 盧丞錫
  36. 華蓋散이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 金聖炫
  37. 紫蘇飮子가 GUINEA PIG의 氣管支平滑筋에 미치는 影響 宋鎭吾
  38. 淸肺湯 및 加味淸肺湯이 Oleicacid로 誘發시킨 家兎의 肺水腫과 GUINEA PIG의 氣管支平滑筋에 미치는 影響 金炳勳
  39. 解表 兩陳湯 및 解表 二陳湯이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 朴千洙
  40. 麻黃散이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 洪在義
  41. 實驗藥物學 고석태;김재완(外)
  42. 黃帝內經 素問譯解 楊維傑
  43. 黃帝內經 靈樞譯解 楊維傑
  44. 中醫內科學 上海中醫學院
  45. 傳統老年醫學 李聰甫
  46. 中藥藥理與應用 王浴生
  47. 漢藥臨床應用 辛民敎;李尙仁;安德均
  48. 中草藥學 上海中醫學院
  49. 申氏本草學 申佶求
  50. 臨床本草學 申民敎
  51. Current Medical Diagnosis & Treatment Krupp, Chatton Werdegar
  52. The Pharmacological Basic of Therapeutics Alfred, Goodman Gilman