• Journal of Communications and Networks
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• 제13권2호
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• pp.86-94
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• 2011

In recent years, there has been a rise in epidemiological evidence suggesting the health benefits of a physically active lifestyle. However, it is not always easy for individuals to personally recognize the optimal conditions for exercise and physical activity. Wearable acceleration-based pedometers have become widely used in estimating the amount of physical activity, and to a limited extent, providing information regarding exercise intensity, but they have never been used to assess adaptation to exercise. In order to realize simultaneous activity monitoring for multiple users exercising outdoors, we developed a prototype wireless local area network (WLAN) based system. In our system, a WLAN is deployed outside, and a user wearing a smart phone and monitoring device exercises freely within the coverage area of the wireless network. By doing so, the developed system is able to monitor the activity of each user andmeasures various parameters including those related to exercise adaptation. In a demonstration experiment, the developed system was evaluated and used to monitor users enjoying a Nordic walk, after which users were immediately able to receive their exercise report. In this paper, we discuss the requirements and issues in developing an activity monitoring system and report the findings we obtained through the demonstration experiment.

• 한국항행학회논문지
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• 제16권4호
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• pp.593-601
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• 2012

본 논문에서는 미래의 다중 Global Navigation Sattelite System (GNSS) 및 다중 주파수 항법신호 사용자를 위한 새로운 다중 가설 사용자 무결성 감시 기법을 제안한다. 기존의 Weighted Least Squares (WLS) 사용자 무결성 감시 (Receiver Autonomous Integrity Monitoring, RAIM) 기법은 동시에 두 개 이상의 위성이 고장 나지 않는다는 가정 하에 사용자 측정치의 무결성을 감시하므로 동시에 두 개 이상의 측정치 이상이 발생하였을 때 적절한 대응을 할 수 없다는 문제가 있다. 본 논문에서는 여러 epoch의 측정치 잔차와 위성 관측행렬의 변화량을 활용하여 단일 고장 뿐만 아니라 다중 고장을 효율적으로 검출할 수 있는 기법을 제안하였다. 제안된 기법은 반송파 위상 측정치의 변화율을 활용하는 Relative RAIM (RRAIM) 기법을 적용하여 최소 검출가능 바이어스 (Minimum Detectable Bias, MDB)의 크기를 최소화하였고, 시뮬레이션 결과 수 십 m 정도 크기의 다중 고장을 검출할 수 있었다.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제4권8호
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• pp.253-258
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• 2015

u-헬스케어 관점에서 볼 때, 심박수(heart rate)는 아픈 사람의 질환을 관리하는 일리스(illness)나 건강한 사람의 건강을 지속적으로 관리하는 웰니스(wellness) 분야에 모두 유용하게 사용된다. 이는 심박수가 질환의 증상을 판단하거나 운동 부하의 지표로서 모두 사용될 수 있기 때문이다. 최근에 착용형 센서(wearable sensors)를 이용하여 상시적으로 심박수를 모니터링하여 이에 기반하여 현재 몸 상태를 점검해볼 수 있는 다양한 심박계(heart rate monitor)와 이와 연동하여 심박수를 이용한 다양한 운동관리 스마트폰 앱이 개발되어 출시되고 있다. 그러나 이러한 스마트폰 앱은 모두 개인 용도로 제한된다. 논문에서는 여러 사람들의 심박수를 동시에 실시간으로 모니터링할 수 있는 시스템을 설계하고, 이를 적용할 수 있는 안드로이드 앱을 개발한다. 개발된 앱의 주요 기능은 다수 이용자에 대한 동시적 심박수 모니터링으로 피트니스 센터에 효과적으로 적용 가능하다.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.288.3-289
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• 2003

Sphingolipid species are important second messengers due to their role in the mitogenesis, differentiation and apoptosis. We developed a new column liquid chromatography-triple quadrupole tandem mass spectrometry (LC-MS/MS) in combination with multiple reaction monitoring (MRM) method for the rapid, simultaneous and quantitative determination of unambiguous detecting sphingolipids in cell culture of human cancer cells (HL-60). (omitted)

• 한국환경보건학회지
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• 제47권1호
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• pp.64-77
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• 2021

Objective: Biological monitoring of trace elements in human blood samples has become an important indicator of the health environment. The purpose of this study was to detect and evaluate multiple metal items in blood samples based on ICP-MS, to perform comparative evaluation with the existing analysis method, and to develop and verify a new method. Methods: 100 μL of whole blood from 80 healthy subjects was used to analyze ten metals (Sb, tAs, Cd, Pb, Mn, Hg, Mo, Ni, Se, Tl) using ICP-MS. Verification of the analysis method included calculation of linearity, accuracy, precision and detection limits. In addition, a comparative test with the conventional graphite furnace atomic absorption spectroscopy (GF-AAS) method was performed. In the case of Pb, Cd, and Hg in whole blood, cross-analysis between Pb, Cd, and Hg analysis methods was performed to confirm the difference between the existing method and the new method (ICP-MS). Results: The coefficient of determination (R2) was 0.999 or higher in seven items and 0.995 or higher in three items. The Pb result showed that Pearson's correlation coefficient was very high at 0.983, and the intraclass correlation coefficient was 0.966. The Cd result showed that Pearson's correlation coefficient was 0.917 between the existing method and the new analysis concentration value. Its intraclass correlation coefficient was 0.960, and there was no significant difference between the two groups. Hg had a low correlation at 0.687, and the intraclass correlation coefficient was 0.761, which was lower than that of Pb and Cd. The intra-day and inter-day accuracy of Pd and Cd were satisfactory, but Hg did not meet the criteria for both accuracy and precision when compared with the conventional analysis method. Conclusion: This study can be meaningful in that it proposes a more efficient and feasible analysis method by verifying a blood heavy metal concentration experiment using multiple simultaneous analyses. All samples were processed and analyzed using the new ICP-MS. It was confirmed that the agreement between the two methods was very high, with the agreement between the current and new methods being 0.769 to 0.998. This study proposes an efficient simultaneous methodology capable of analyzing multiple elements with small samples. In the future, studies of various applications and the reliability of ICP-MS analysis methods are required, and research on the verification of accurate, precise, and continuous analysis methods is required.

• Structural Monitoring and Maintenance
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• 제6권3호
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• pp.237-254
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• 2019

This paper presents an improved time series based damage detection approach with experimental verifications for detection, localization, and quantification of damage in shear-type structures under varying mass effects using output-only vibration data. The proposed method can be very effective for automated monitoring of buildings to develop proactive maintenance strategies. In this method, Auto-Regressive Moving Average models with eXogenous inputs (ARMAX) are built to represent the dynamic relationship of different sensor clusters. The damage features are extracted based on the relative difference of the ARMAX model coefficients to identify the existence, location and severity of damage of stiffness and mass separately. The results from a laboratory-scale shear type structure show that different damage scenarios are revealed successfully using the approach. At the end of this paper, the methodology limitations are also discussed, especially when simultaneous occurrence of mass and stiffness damage at multiple locations.

• Journal of Applied Biological Chemistry
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• 제57권1호
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• pp.89-93
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• 2014

We aim to develop a simple method for simultaneous and quantitative determination of benzoic acid, caffeic acid and chlorogenic acid in seeds of Eriobotrya japonica. In addition, antibacterial effect of these three phenolic acids was examined. A basic method is performed on the high performance liquid chromatography system coupled to an UV-detector (230 nm) and reverse phase C-18 column ($4.6{\times}150mm$, $5{\mu}m$). Each phenolic acid was confirmed via liquid chromatography-mass spectrometry (MS)/MS system under the multiple-reaction monitoring with negative-ion electrospray ionization (ESI(-)) mode. It is demonstrated that the method was could be applied to samples for an analytical study of the phenolic acids. On the other hand, three phenolic acids in seeds of E. japonica exhibited antibacterial effect against several pathogenic bacteria. Of these, benzoic acid was found to have stronger antibacterial effect.

• 분석과학
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• 제23권4호
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• pp.405-413
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• 2010

축산물(소의 근육 및 간)중에 잔류하는 합성 글루코코티코이드 6종 (betamethasone, dexamethasone, prednisone, prednisolone, methylprednisolone, flumethasone)에 대한 동시분석방법을 확립하였다. 효과적인 기기분석을 위해서 시료는 C18 고체상 카트리지를 사용하여 에틸아세테이트 용매를 사용하여 추출/정제하였다. C18 컬럼을 사용하여 분리한 후 음이온 전기분무 질량분석법의 multiple reaction monitoring 방법을 사용하여 정량 및 정성 분석을 수행하였다. 효과적이고 감도있는 HPLC-MS/MS 분석을 위해서 0.1% 포름산이 포함된 물과 아세토나이트릴이 이동상 용매로 사용되었다. 메트릭스와 약물의 종류에 따라서 검출한계(LOD)는 $0.2-0.1\;{\mu}g$/kg, 정량한계(LOQ)는 $0.8-3.4{\mu}g$/kg 이었으며, 회수율은 89.5-119.6%이었다. 확립된 기존의 방법들에 비해 6종의 글루코코티코이드의 동시분석 방법이 간소화되었고, 좋은 정확도, 정밀도 및 회수율을 나타내었으며, 축산 육류 중에 잔류하는 글루코코티코이드들 분석하는데 사용될 수 있을 것이다.

• 한국산학기술학회논문지
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• 제15권5호
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• pp.3100-3106
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• 2014

본 논문에서는 전력 시스템의 전원 및 부하 측을 동시에 감시가 가능한 다 채널(전압 8채널, 전류 10채널) 전력 측정 시스템을 개발하였다. 제안된 시스템은 전력품질과 관련된 규정인 IEEE 1459-2010의 정의를 사용하여 전력 성분을 계산하는 신호처리 알고리즘을 기반으로 TMS320C42 DSP를 이용하여 개발하였다. 개발된 시스템은 표준 전원 공급 장치를 이용하여 그 성능 시험을 실시하였고, 그 결과 측정오차는 0.2% 이하로 나타났다. 또한 제안된 시스템을 3상 4선식 전력시스템에 설치하여 실증 시험을 실시하여 그 성능을 입증하였다. 제안된 시스템은 상업 및 산업용 전력 시스템에 적용하여 동시에 다 채널로 전력을 측정 및 분석함으로써 전력품질과 관련된 다양한 문제를 줄일 수 있을 것이다.

• Biomedical Engineering Letters
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• 제8권4호
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• pp.365-371
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• 2018

Uninterrupted monitoring of multiple subjects is required for mass causality events, in hospital environment or for sports by medical technicians or physicians. Movement of subjects under monitoring requires such system to be wireless, sometimes demands multiple transmitters and a receiver as a base station and monitored parameter must not be corrupted by any noise before further diagnosis. A Bluetooth Piconet network is visualized, where each subject carries a Bluetooth transmitter module that acquires vital sign continuously and relays to Bluetooth enabled device where, further signal processing is done. In this paper, a wireless network is realized to capture ECG of two subjects performing different activities like cycling, jogging, staircase climbing at 100 Hz frequency using prototyped Bluetooth module. The paper demonstrates removal of baseline drift using Fast Fourier Transform and Inverse Fast Fourier Transform and removal of high frequency noise using moving average and S-Golay algorithm. Experimental results highlight the efficacy of the proposed work to monitor any vital sign parameters of multiple subjects simultaneously. The importance of removing baseline drift before high frequency noise removal is shown using experimental results. It is possible to use Bluetooth Piconet frame work to capture ECG simultaneously for more than two subjects. For the applications where there will be larger body movement, baseline drift removal is a major concern and hence along with wireless transmission issues, baseline drift removal before high frequency noise removal is necessary for further feature extraction.