• Archives of Plastic Surgery
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• v.34 no.2
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• pp.181-185
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• 2007

Purpose: Cleft lip and/or palate is the most common congenital facial anomaly whose incidence is about 1 in 500~1000 live births. As this anomaly may be associated with the serious chromosomal anomalies or the multiple organ abnormalities resulting in the fetal loss or perinatal maternal morbidity and mortality, careful prenatal counseling with early and accurate detection is important. Although conventional prenatal ultrasound(US) examination in midterm pregnancy has been applied for screening of cleft lip, there are definite limitations in the diagnosis of accompanying cleft palate or alveolar cleft. We applied high-resolution 3D US along the serial axial, coronal and sagittal plane so that we could diagnose the cleft palate and/or alveolar cleft in fetuses with cleft lip. Methods: From May 2005 to September 2005, 20 fetuses with cleft lip were examined with prenatal 3D US. Average maternal age was 28.8 years old(24-35 years old), and average gestational age was 24.8 weeks(17.6 to 34.2 weeks). Consecutive axial, coronal and sagittal multislice view were obtained via prenatal 3D US examination and diagnosis of cleft palate and/or alveolar cleft in cleft lip fetuses was followed. Results: With noninvasive and safe prenatal 3D US examination, 17 of 20 cleft lip fetuses were demonstrated to have cleft palate and/or alveolar cleft. Prenatal counseling according to the result was made. Conclusion: Existing prenatal US examination is suitable for screening the cleft lip fetuses but has limitation in identifying the related existence of cleft palate and/ or alveolar cleft. Authors verify the presence of cleft palate and/or alveolar cleft acquiring the successive multislice axial, coronal, and sagittal view with prenatal 3D US examination. Therefore, prenatal 3D US examination could be regarded as a noninvasive and secure screening modality in fetuses with cleft lip for confirming whether cleft palate and/or alveolar cleft is accompanied.

• Journal of Life Science
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• v.23 no.2
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• pp.324-331
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• 2013

The addition and removal of N-acetylglucosamine (GlcNAc) molecules on serine or threonine residues of a protein is called O-GlcNAcylation. This post-translational modification occurs on both cytoplasmic and nuclear protein, and is fast and reversible as comparable to phosphorylation. In contrast to the phospho-signaling cycles, this emerging moon-lightening signaling is cycled by only two enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). The simple machinery is a good evolutionary adaptation of a cell for quick accommodation to continuously fluctuating intra- and extracellular microenvironments. Rather than "switching" on or off a specific proteins - this would be done by phosphorylation where numerous specific kinases and phosphatases are involved - O-GlcNAcylation would play a "rheostat" which would be much more delicately increase or decrease the efficacy of signal transductions in response to cellular nutrient and stress conditions. Interestingly, recent evidence indicates that O-GlcNAc is further modified by phosphorylation. The O-GlcNAc-P will upgrade the modulation efficiency of cellular processes to continuous 'analogue' level. So far, only one protein AP180 was reported to have O-GlcNAc-P on Thr310. But, proteomic data from our laboratory indicate that there are multiple O-GlcNAc-P proteins, constituting "O-GlcNAc-P'om". This will focus on the possibility of existence of "O-GlcNAc-P'om".

• Journal of Science and Technology Studies
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• v.19 no.3
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• pp.167-200
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• 2019

In recent years, the material has mattered to the humanities and social sciences in the West and feminism is no exception. It is a notable change that feminist analyses, which had previously shown critiques against science and technology, attempted to build new engagements with matter. STS (science and technology studies) has also accumulated scholarships and developed conceptual tools on the thing or the existence itself through "the ontological turn." The objective of this paper is not to introduce new materialism or new material feminism in full, but to reveal the possibility and potential of doing science, technology and women studies by selectively relying on the achievement of new materialism feminism. This article shows a way to study women's practice of science and technology by analyzing the case of plastic surgery practices through the ontological concepts of STS, particularly those of Annemarie Mol, Karen Barad, and Charis Thompson, and proposes a new engagement among new materialism, feminism, and STS. This article is organized as follows. First of all, after briefly discussing main issues in new material feminism, I will show the limitations of previous feminist studies of plastic surgery under the light of new material feminism. The rest of the article introduces the conceptual tools of ontological STS, describes plastic surgery practices with those tools, and finally provides their feminist implications.

• 재활복지
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• v.20 no.4
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• pp.1-29
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• 2016

The research regarding employees' job satisfaction is one of the most important indicators of their vocational adjustment or outcome. The purpose of this study is to investigate the level of job satisfaction of South Korean masseurs with visual impairments and what variables predict to this. The work satisfaction model of Social Cognitive Career Theory (Lent Brown, 2006a) was grounded. a total of 221 South Korean masseurs with visual impairments participated in this study. Multiple regression analysis indicated that as masseurs in this study experienced having a better fit with their job regarding their monetary aspects, as they felt efficacious with their massage skills, as they felt more positive, and as they considered their job duties fit their education or skills they learned, their level of job satisfaction was higher. However, fit with their organization values or cultures or how much they get social support from their family, friends, or significant others did not predict their job satisfaction. In addition, the analysis supported the existence of a moderating effect of positive affect on the relationship between subjective fit and job satisfaction, in addition to the moderating effect of social support on the relationship between work related self-efficacy and job satisfaction among study participants. Implications for policy makers, researchers, and career counselors were also provided.

• Science of Emotion and Sensibility
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• v.22 no.1
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• pp.3-14
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• 2019

This exploratory study investigated the effects of the interaction between the experience of social exclusion and the presence or absence of a companion animal on the psychological well-being of individuals. Participants answered questions about whether or not they were respected by the community (yes or no); whether or not they currently have a companion animal (yes or no); and if they do, what kind of animal(s) they raise (multiple answers allowed). The study also assessed the psychological well-being of the participants. The group that experienced social exclusion demonstrated lower levels of psychological well-being than the group that did not. In addition, the group that reported the presence of at least one companion animal evinced higher levels of psychological well-being than the group that did not. Individuals who experienced social exclusion but lived with at least one companion animal were found to display superior psychological well-being than those who could not avail of the company of an animal. No difference in psychological well-being was found between those with a companion animal and those without one in the group that did not experience social exclusion. In conclusion, this study observed the effects of the binary interactions between social exclusion (experienced vs. not experienced) and the existence of companion animals (presence vs. absence) on the psychological well-being of people. The empirical data offer theoretical implications for the conditions in which companion animals do or do not improve psychological well-being in humans.

• Journal of Life Science
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• v.31 no.2
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• pp.248-255
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• 2021

Mammary gland tumors are one of the most common cancers in female dogs, and there are various types of cells depending on the tumor type. Complex carcinoma consists of a combination of luminal epithelial and myoepithelial cells with intra-tumoral heterogeneity. However, the origins of these tumor cells and their effects on the malignancies of tumors have not been identified. Recently, it has been reported that cancer stem cells, identified in several types of human tumors, are involved in tumor heterogeneity and may also contribute to malignancies such as tumor recurrence and metastasis. Interestingly, cancer stem cells share several abilities of self-renewal and cell differentiation into multiple types of cancer cells, but they have abnormal genetic mutation and signal transduction pathways to regulate the maintenance of stem cell characters. Moreover, it is known that these cell populations contribute to cell metastasis as well as cell resistance against chemo- and radio-therapeutics that promote tumor recurrence. The existence of cancer stem cells might explain the intra-tumoral heterogeneity and cancer aggressiveness during tumorigenesis in canine mammary gland tumors. This review summarizes the characteristics and types of canine mammary gland tumors, the definition of tumor stem cells, methods of isolation, and clinical significance.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.336-344
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• 2021

The purpose of this study was to identify the self-awareness of smartphone dependence among undergraduate students and their response to the same. The data was drawn from a survey on smartphone overdependence conducted by the Ministry of Science and information and communications technology (ICT) and the National Information Society Agency in 2017. The responses of 1,735 undergraduate students were analyzed by frequency, percentage, mean, standard deviation, minimum-maximum value, ��2-test, independent t-test, Pearson's correlation coefficient, and stepwise multiple regression analysis. The results indicated that 22.3% of participants were at risk of smartphone dependence, and 63.6% of them were unaware of their dependence on smartphones. The perception of smartphone dependence was significantly associated with a higher risk of smartphone dependence (��=.35, p=.000) and the increasing use of applications such as games (��=.19, p=.000), television/video (��=.11, p=.000), and learning (��=.11, p=.000). Of the participants with dependence awareness, only a few knew about the existence of centers to prevent smartphone and internet dependence. Moreover, they rarely utilized these centers. However, the participants felt the need for more counseling agencies (26.8%), programs for dealing with oneself (23.2%), information about smartphone dependence (14.9%), and help to overcome dependence (10.9%). These findings show the need to establish public services so that students can easily access correct information on smartphone dependence and address this problem.

• Journal of the Daesoon Academy of Sciences
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• v.25_2
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• pp.177-213
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• 2015

We live in two giant pendulum in called 'science' and 'religion'. But science and religion are contained in disparate information with each other, Those two is not easy to achieve convergence. But if you accept the ontological scheme of Great Chain of Being(存在의 大連鎖) in the Perennial philosophy(永遠의 哲學), Debate between religion and science is meaningless 'Great Nest of Being(存在의 대둥지, Great Chain of Being)' is similar to the multiple concentric circles, there are different dimension that the each top level to subsume surrounding the lower level. For example, upper zone 'Mysticism(神秘主義)' includes but transcends(or transcends but includes.) the sub-region theology, psychology, biology and physics. The Perennial philosophy is the great spiritual teachers of the world, philosophers and thinkers have adopted a common worldview, a religious views. Philosophers of the perennial philosophy seem to match the cross-cultural almost unanimous about the general level of the 'Great Nest of Being' for the past 3,000 years. The perennial philosophy made the conclusion that God exists in the world. Several types of view of God existing religions in the world have 'Monotheism(一神論)', 'Pantheism(汎神論)' and 'Panentheism (汎在神論)'. Although traditionally the God of the philosophers is the classical Theism, theological trends of today it is moving in the direction of Panentheism. Panentheism see that god is immanent and transcendent. also Daesoon Thoughts is the position of the Panentheism. so this paper points out the fact that the view of God of the perennial philosophy is precisely consistent with the view of God of Daesoon Thoughts. Wilber says 'envelopment [transcend and include]'. The word translates as 'powol(包越)' in Korean. 'Powol(包越)' means that all the developmental evolution is to surround the sub-region developed into the higher realms. View of the God in the perennial philosophy is 'powol theism(包越的 有神論)'. but 'powol immanent God(包越的 內在神論)' rather than building regulations as 'powol theism(包越的 有神論)'. It would have to be a more accurate representation of it. Because in the existing 'theism(有神論)' the god and humans are thought to exist apart. However, Daesoon Thoughts are deemed to also recognize another universal laws. also Sangje(上帝, the Supreme God) is recognized as a cosmic existence that transcends the laws. This point, as the characteristics of the Daesoon Thoughts, In other religions can not be found. Therefore, More specifically represent(More accurately represent), Sangje of the Daesoon Thoughts can be described as 'powol theism' or 'transcendental and included deism(包越的 理神論)'. Importantly, The idea of God can be captured directly by the discipline. In this sense, In terms of the other religions have no discipline law, the practice [discipline] of the Daesoon Thoughts required in the present age. It has the absoluteness.

• 한국노년학
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• v.29 no.1
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• pp.275-289
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• 2009

The purpose of this study is to explore effective factors of elderly people's overall death anxiety and sub-dimensions of death anxiety. The subjects were 156 elderly people in S City, Gyeonggi-Do gathered by convenience sampling. This study collected data by interviewing the elderly who agreed to participate in the study and then analyzed it using SPSS 12.0 through descriptive statistics, the t-test, F-test, Sheffe-test, correlation analysis, and multiple regression. The respondents' overall death anxiety score was 2.61(±.47), and 'anxiety in the dying process'(2.94) had the highest points among sub-dimensions. Effective factors of overall level of death anxiety among the elderly were 'age' (β=-.18, p=.015), 'education' (β=-.16, p=.045), and 'economic status' (β=-.26, p=.003). In sub-dimensions, the elderly who were female, relatively young, and had low economic status showed high 'anxiety in the dying process'. As for 'anxiety over what will happen after one's death', the elderly who were relatively young, and had low economic status had high scores. Finally, on 'the loss of existence', the elderly who had poor relationships with their families had high scores.

• Journal of the Korea Knowledge Information Technology Society
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• v.13 no.3
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• pp.305-317
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• 2018

This study is about the elderly people's use and experience of Virtual Reality (VR) in order to enhance their quality of life. Leisure is main activity of the elderly. As a result, the quality and diversity of leisure affects the quality of the elderly people's life. VR services including video contents could provide them with advanced and interesting experiences. Across the world, population aging becomes one of the most important problems in each society. The social and economic burden of aging is serious challenge to sustainability welfare of the world, including S. Korea. The authors used virtual reality devices to conduct experiments on 99 aged 50 to 90 (men's average age : 75 and women's average age : 70.8). Through the survey, major variants were measured such as system quality, present sense, enjoyment, intent to reuse, and awareness of advanced technology. Multiple regression analyses with the presence as a dependent variable resulted in a sense of closeness (t = 5.381, p <. 01) and a sense of clarity (t = 4.494, p <. 01). The presence of an independent variant had significant effects on pleasure (t = 4.312, p <. 01) and significant effects on the intent to reuse (t = 3.323,).Therefore, it can be interpreted that the higher the sense of existence, the more pleasure and the intent to reuse it. As a result, the possibility of using VR devices and content to enjoy leisure activities can be found in this study even if the elderly group is unfamiliar with IT devices.