• Korean Journal of Medicinal Crop Science
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• v.22 no.4
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• pp.262-269
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• 2014

Complex of mulberry extract (CME) is composed of extracts of mulberry (Morus alba L.) fruit, mulberry leaves and black beans (Glycine max (L.) Merr.). In this study, we investigated prevention effects of CME on degenerative arthritis. The $SC_{50}$ value of DPPH radical scavenging by CME was $158.49{\pm}11.35{\mu}/mL$. We found that CME significantly reduced the production of nitric oxide (NO) and protein expression of cyclooxygenase-2 (COX-2) in RAW 264.7 cells which were activated by LPS. Experiments using animal model of degenerative arthritis showed that CME (400 mg/kg body weight) inhibited the production of TNF-${\alpha}$ (77.5%) and IL-$1{\beta}$ (95.0%). Furthermore, it was observed that CME reduced to 85.9% of paw edema induced by carrageenan. These results suggest that CME could improve degenerative arthritis.

• Korean journal of food and cookery science
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• v.10 no.4
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• pp.346-350
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• 1994

This investigation was undertaken for the purpose of studying the effect of the addition of the powder(0, 1, 2, 3%)from fruit of paper mulberry(Broussonetia Kazinoki SieboId) on the hardness, cohesiveness, elasticity, gumminess, chewiness, cooking loss and sensory characteristics of cooked ground beef with or without soysauce. The results obtained were summerized as follows; Hardness, gumminess, chewiness, and cooking loss were decreased by increasing the percent of adding the powder from the fruit of paper mulberry. As a result of sensory evaluation for cooked ground beef, sample with powder from the fruit of paper mulberry showed the higher scores in most of the characteristics. And cooked ground beef added the powder from the fruit of paper mulberry with soysauce showed the higher decreasing rate of hardness than those of without soysauce.

• International Journal of Industrial Entomology and Biomaterials
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• v.7 no.1
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• pp.69-73
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• 2003

Specific leaf weight (SLW), defined as the mass of tissue per unit leaf area has been found to be an important physiological parameter as it indicates the relative thickness of leaves. Greater SLW provides more photosynthetic potential per unit area of leaf and hence it is frequently been considered as correlated with photosynthesis in several plant species. Collections of 165 mulberry (Morus sp.) germplasm accessions, both Indian and exotic in origin were evaluated for their variability with respect to SLW. The mean specific leaf weight ranged from 35.3 to $72.3 g/m^{-2}$. The distribution of SLW was found to be normal. High heritability (97.08%) and a small difference between genotypic and phenotypic variance demonstrates the genetic control over SLW. Significant heterotic effect with respect to SLW was observed in crosses when parents with high and low SLW were chosen.

• International Journal of Industrial Entomology and Biomaterials
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• v.7 no.1
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• pp.83-86
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• 2003

Mulberry plantations are prone to several kinds of insect pests including the thrips, Pesudodendrothrips mori. The thrips infestation affects the qualitative and quantitative characters of mulberry leaf, which in turn affects the silkworm cocoon crop. In the present study, four commercial insecticides viz., Rogor, Quinalphos, Confidor and Methyl parathion were tested for their efficacy in the control of P. mori thrips. These insecticides were observed to kill 68-80％ within 24 hrs in vivo and 100％ after 12 hrs post-treatment in vitro. Confidor (0.05％) and Quinalphos (0.2％) were most effective in controlling the thrips incidence. The insecticide-sprayed mulberry leaves did not show any adverse effect on the rearing of silkworms.

• International Journal of Industrial Entomology and Biomaterials
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• v.15 no.2
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• pp.145-155
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• 2007

Mulberry (Morus spp.) is an economically important tree crop being cultivated in India, China and other sericulturally important countries for its foliage to feed the silk producing insect Bombyx mori L. Genetic improvements of mulberry lag behind to the same in many other economically less important crops due to the complexity of its genetics, the breeding behavior, and the lack of basic information on factors governing important agronomic traits. In this review, the general usage and advantages of different molecular markers including isoenzymes, RFLPs, RAPDs, ISSRs, SSRs, AFLPs and SNPs are described to enlighten their applicability in mulberry genetic improvement programs. Application of DNA markers in germplasm characterization, construction of genetic linkage maps, QTL identification and in marker-assisted selection was also described along with its present status and future prospects.

• International Journal of Industrial Entomology and Biomaterials
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• v.5 no.1
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• pp.131-134
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• 2002

Mulberry being the only food of silkworm, Bombyx mori L., is of great economic importance to the silk industry, The success in cocoon production mainly depends on the supply of quality leaves in sufficient quantity. In mulberry, where the economic product is leaf, the uptake of nitrogen from soil is very heavy and high responses to application of nutrients have been reported. Nitrogen supports vegetative growth particularly the leaf biomass. Variation in nitrogen harvest index and other physiological and yield contributing traits were estimated in five mulberry genotypes. Considerable variation was observed for nitrogen harvest index, protein yield per plant and harvest index. The correlation studies indicated the protein yield per plant was significantly correlated with leaf yield, nitrogen content in leaf, nitrogen harvest index and harvest index. The broad sense heritability estimates revealed that harvest index showed highest heritability (88.07%) followed by nitrogen content (82.52%), protein yield (70.28%) and nitrogen harvest index (66.52%).

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.45 no.3
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• pp.36-44
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• 2013

This study is focused on the debarking and xylem separation yield of Paper Mulberry. We investigated the most efficient manual on the automatic debarking and xylem separator machine. The bast tissues of Paper Mulberry were separated in three layers including black outer layer, green inner layer, and white inner layer. A target is to save the white inner layer of these three layers as much as possible. The experimental machine most characterize xylem separation and debarking by frictional force between the bulges and Paper Mulberry by the drum rotation. It is possible automatically to operate the machine by controlling the temperature sensor and the time. Debarking process can be know that removed black outer layer has beem accumulate and measured the weight. The content of the extract, holocellulose, lignin and ashes of the white inner layer was analyzed. It is result that conditions of optimum process of the experimental machine is 45 RPM, temperature at $60^{\circ}C$(60 min.) and $80^{\circ}C$(60 min.), mixing bulge of 10 mm(120ea) and 30 mm(120ea) and capacity of Paper Mulberry 10 kg.

• International Journal of Industrial Entomology and Biomaterials
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• v.34 no.2
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• pp.38-44
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• 2017

Mulberry leaves containing 1-deoxynojirimycin (DNJ) have been recognized as a potentially important source for prevent or treat hyperglycemia. However, DNJ content of natural mulberry leaf are as low as 0.1%. Thus, the most effective method for increasing ${\alpha}$-glucosidase inhibitory activity with the DNJ high-production is needed. In this study, we investigated the influence of ${\alpha}$-glucosidase inhibitory activity according to different pH values (6-9) and inoculation amounts (0.1-0.5%) when Bacillus subtilis cultured on mulberry leaf powder media. We confirmed that ${\alpha}$-glucosidase inhibitory activity was difference according to culture conditions of different pH values, inoculation amounts, and fermentation times. The results of mulberry leaf fermentation according to pH values and inoculation amounts were shown that the optimal conditions for ${\alpha}$-glucosidase inhibitory activity were defined as pH 7 and 9, inoculation amount 0.4%, and incubation until 2 to 4 days. These results can be provided a basic data for the optimal culture conditions increasing ${\alpha}$-glucosidase inhibitory activity from mulberry leaf fermentation.

• International Journal of Industrial Entomology and Biomaterials
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• v.8 no.1
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• pp.1-15
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• 2004

Due to recent scientific innovations in mulberry cultivation, leaf yield has been increased manifold. However, with successive leaf harvest, a quantum drop in leaf yield and quality has been noted. This inturn has affected the silkworm rearing and farmers suffered by the frequent crop failures. This is mainly due to nutrient deficiencies in mulberry leaf. Moreover, no complete information is available about hunger signs of nutritional disorders, analytical diagnosis and critical levels of nutrients required. The present paper, thus, may serve as an important nutrient guide for identification of hunger signs, leaf nutrients status under deficiency and critical levels of the elements namely N, P, K, Ca, Mg, S, B, Cu, Fe, Mn and Zn requirements for higher leaf yield and quality. The leaf nutrient status provided may help chemist for correcting the soil status. Besides, an integration of mulberry intercropping with legumes and applications of neem and castor oil cakes, VA-mycorrhizal inoculation, biofertilizer and vermicompost are suggested as integrated nutrient management for sustainable sericulture industry. Based on the information described in this paper, a model needs to be framed for maintaining continuous supply of nutrients to obtain desired quantity and quality of mulberry leaf for successful silkworm cocoon crop and increasing overall silk productivity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.5
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• pp.830-836
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• 2011

The leaf of mulberry (Morus alba L) has long been used in Oriental medicine for the prevention or treatment of several diseases. However, little is known about the inhibitory effects of a single compound isolated from the mulberry leaves on inflammatory response. We are isolate a single compound of quercetin (3,3',4',5,7-pentahydroxyflavone) and astragalin (kaempferol-3-O-glucopyranoside) from the mulberry leaves, and then investigate the anti-inflammatory effects of quercetin, astragalin or quercetin plus astragalin in lipopolysaccharide (LPS)-stimulated murine peritoneal macrophages. Each compound suppressed the production of inflammatory mediators (NO, $PGE_2$ and IL-6) in LPS-stimulated murine peritoneal macrophages in a dose-dependent manner. Especially, the cotreatment of quercetin (2.5 ${\mu}M$) and astragalin (2.5 ${\mu}M$) markedly suppressed the production and the expression of inflammatory mediators. These suppressive effects were synergistically increased by their combination. These results suggest that the combination of quercetin and astragalin from the mulberry leaves may be useful for therapeutic drugs against inflammatory immune diseases, probably by suppressing the production of inflammatory mediators.