• 제목/요약/키워드: monte carlo method

검색결과 2,172건 처리시간 0.027초

Cerebral Oxygenation Monitoring during a Variation of Isoflurane Concentration in a Minimally Invasive Rat Model

  • Choi, Dong-Hyuk;Kim, Sungchul;Shin, Teo Jeon;Kim, Seonghyun;Kim, Jae Gwan
    • Current Optics and Photonics
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    • 제6권5호
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    • pp.489-496
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    • 2022
  • Our previous study on monitoring cerebral oxygenation with a variation of isoflurane concentration in a rat model showed that near-infrared spectroscopy (NIRS) signals have potential as a new depth of anesthesia (DOA) index. However, that study obtained results from the brain in a completely invasive way, which is inappropriate for clinical application. Therefore, in this follow-up study, it was investigated whether the NIRS signals measured in a minimally invasive model including the skull and cerebrospinal fluid layer (CSFL) are similar to the previous study used as a gold standard. The experimental method was the same as the previous study, and only the subject model was different. We continuously collected NIRS signals before, during, and after isoflurane anesthesia. The isoflurane concentration started at 2.5% (v/v) and decreased to 1.0% by 0.5% every 5 min. The results showed a positive linear correlation between isoflurane concentration and ratio of reflectance intensity (RRI) increase, which is based on NIRS signals. This indicates that the quality of NIRS signals passed through the skull and CSFL in the minimally invasive model is as good as the signal obtained directly from the brain. Therefore, we believe that the results of this study can be easily applied to clinics as a potential indicator to monitor DOA.

Particle loading as a design parameter for composite radiation shielding

  • Baumann, N.;Diaz, K. Marquez;Simmons-Potter, K.;Potter, B.G. Jr.;Bucay, J.
    • Nuclear Engineering and Technology
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    • 제54권10호
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    • pp.3855-3863
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    • 2022
  • An evaluation of the radiation shielding performance of high-Z-particle-loaded polylactic acid (PLA) composite materials was pursued. Specimens were produced via fused deposition modeling (FDM) using copper-PLA, steel-PLA, and BaSO4-PLA composite filaments containing 82.7, 75.2, and 44.6 wt% particulate phase contents, respectively, and were tested under broad-band flash x-ray conditions at the Sandia National Laboratories HERMES III facility. The experimental results for the mass attenuation coefficients of the composites were found to be in good agreement with GEANT4 simulations carried out using the same exposure conditions and an atomistic mixture as a model for the composite materials. Further simulation studies, focusing on the Cu-PLA composite system, were used to explore a shield design parameter space (in this case, defined by Cu-particle loading and shield areal density) to assess performance under both high-energy photon and electron fluxes over an incident energy range of 0.5-15 MeV. Based on these results, a method is proposed that can assist in the visualization and isolation of shield parameter coordinate sets that optimize performance under targeted radiation characteristics (type, energy). For electron flux shielding, an empirical relationship was found between areal density (AD), electron energy (E), composition and performance. In cases where ${\frac{E}{AD}}{\geq}2MeV{\bullet}cm{\bullet}g^{-1}$, a shield composed of >85 wt% Cu results in optimal performance. In contrast, a shield composed of <10 wt% Cu is anticipated to perform best against electron irradiation when ${\frac{E}{AD}}<2MeV{\bullet}cm{\bullet}g^{-1}$.

A novel radioactive particle tracking algorithm based on deep rectifier neural network

  • Dam, Roos Sophia de Freitas;dos Santos, Marcelo Carvalho;do Desterro, Filipe Santana Moreira;Salgado, William Luna;Schirru, Roberto;Salgado, Cesar Marques
    • Nuclear Engineering and Technology
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    • 제53권7호
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    • pp.2334-2340
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    • 2021
  • Radioactive particle tracking (RPT) is a minimally invasive nuclear technique that tracks a radioactive particle inside a volume of interest by means of a mathematical location algorithm. During the past decades, many algorithms have been developed including ones based on artificial intelligence techniques. In this study, RPT technique is applied in a simulated test section that employs a simplified mixer filled with concrete, six scintillator detectors and a137Cs radioactive particle emitting gamma rays of 662 keV. The test section was developed using MCNPX code, which is a mathematical code based on Monte Carlo simulation, and 3516 different radioactive particle positions (x,y,z) were simulated. Novelty of this paper is the use of a location algorithm based on a deep learning model, more specifically a 6-layers deep rectifier neural network (DRNN), in which hyperparameters were defined using a Bayesian optimization method. DRNN is a type of deep feedforward neural network that substitutes the usual sigmoid based activation functions, traditionally used in vanilla Multilayer Perceptron Networks, for rectified activation functions. Results show the great accuracy of the DRNN in a RPT tracking system. Root mean squared error for x, y and coordinates of the radioactive particle is, respectively, 0.03064, 0.02523 and 0.07653.

Secondary Neutron Dose in Carbon-ion Radiotherapy: Investigations in QST-NIRS

  • Yonai, Shunsuke;Matsumoto, Shinnosuke
    • Journal of Radiation Protection and Research
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    • 제46권2호
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    • pp.39-47
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    • 2021
  • Background: The National Institutes for Quantum and Radiological Science and Technology-National Institute of Radiological Sciences (QST-NIRS) has continuously investigated the undesired radiation exposure in ion beam radiotherapy mainly in carbon-ion radiotherapy (CIRT). This review introduces our investigations on the secondary neutron dose in CIRT with the broad and scanning beam methods. Materials and Methods: The neutron ambient dose equivalents in CIRT are evaluated based on rem meter (WENDI-II) measurements. The out-of-field organ doses assuming prostate cancer and pediatric brain tumor treatments are also evaluated through the Monte Carlo simulation. This evaluation of the out-of-field dose includes contributions from secondary neutrons and secondary charged particles. Results and Discussion: The measurements of the neutron ambient dose equivalents at a 90#x00B0; angle to the beam axis in CIRT with the broad beam method show that the neutron dose per treatment dose in CIRT is lower than that in proton radiotherapy (PRT). For the scanning beam with the energy scanning technique, the neutron dose per treatment dose in CIRT is lower than that in PRT. Moreover, the out-of-field organ doses in CIRT decreased with distance to the target and are less than the lower bound in intensity-modulated radiotherapy (IMRT) shown in AAPM TG-158 (American Association of Physicists in Medicine Task Group). Conclusion: The evaluation of the out-of-field doses is important from the viewpoint of secondary cancer risk after radiotherapy. Secondary neutrons are the major source in CIRT, especially in the distant area from the target volume. However, the dose level in CIRT is similar or lower than that in PRT and IMRT, even if the contributions from all radiation species are included in the evaluation.

Radioisotope identification using sparse representation with dictionary learning approach for an environmental radiation monitoring system

  • Kim, Junhyeok;Lee, Daehee;Kim, Jinhwan;Kim, Giyoon;Hwang, Jisung;Kim, Wonku;Cho, Gyuseong
    • Nuclear Engineering and Technology
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    • 제54권3호
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    • pp.1037-1048
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    • 2022
  • A radioactive isotope identification algorithm is a prerequisite for a low-resolution scintillation detector applied to an unmanned radiation monitoring system. In this paper, a sparse representation with dictionary learning approach is proposed and applied to plastic gamma-ray spectra. Label-consistent K-SVD was used to learn a discriminative dictionary for the spectra corresponding to a mixture of four isotopes (133Ba, 22Na, 137Cs, and 60Co). A Monte Carlo simulation was employed to produce the simulated data as learning samples. Experimental measurement was conducted to obtain practical spectra. After determining the hyper parameters, two dictionaries tailored to the learning samples were tested by varying with the source position and the measurement time. They achieved average accuracies of 97.6% and 98.0% for all testing spectra. The average accuracy of each dictionary was above 96% for spectra measured over 2 s. They also showed acceptable performance when the spectra were artificially shifted. Thus, the proposed method could be useful for identifying radioisotopes in gamma-ray spectra from a plastic scintillation detector even when a dictionary is adapted to only simulated data. Furthermore, owing to the outstanding properties of sparse representation, the proposed approach can easily be built into an insitu monitoring system.

Gadolinium- and lead-containing functional terpolymers for low energy X-ray protection

  • Zhang, Yu-Juan;Guo, Xin-Tao;Wang, Chun-Hong;Lu, Xiang An;Wu, De-Feng;Zhang, Ming
    • Nuclear Engineering and Technology
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    • 제53권12호
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    • pp.4130-4136
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    • 2021
  • By polymerization of gadolinium methacrylate (Gd (MAA)3), lead methacrylate (Pb(MAA)2) and methyl methacrylate (MMA), Gd and Pb were chemically bonded into polymers. The X-ray shielding performance was evaluated by Monte Carlo simulation method, and the results showed that the more metal functional organic monomer, the better the shielding performance of terpolymers. When the X-ray energy is 65 keV, Gd (MAA)3-containing polymers have better shielding performance than Pb(MAA)2-containing polymers. Gd could compensate for the weak absorption region of Pb. Therefore, polymers containing both Gd and Pb enhanced shielding efficiency against X-ray in various low-energy ranges. For obtaining terpolymers with uniform monomer compositions, the relationship between the monomer composition of the terpolymers and the conversion level was optimized by calculating the reactivity ratios. The value of reactivity ratios of r (Gd (MAA)3/Pb(MAA)2), r (Pb(MAA)2/Gd (MAA)3), r (Gd (MAA)3/MMA), r (MMA/Gd (MAA)3), r (Pb(MAA)2/MMA) and r (MMA/Pb(MAA)2) was 0.483, 0.004, 0.338, 2.508, 0.255, 0.029. The terpolymers with uniform monomer composition could be obtained by controlling the monomer compositions or conversion levels. The results can provide new radiation protection materials and contribute to the improvement in nuclear safety.

가우시안 과정 분류에 대한 변분 베이지안 다항 프로빗 모형: 쥐 단백질 발현 데이터에의 적용 (Variational Bayesian multinomial probit model with Gaussian process classification on mice protein expression level data)

  • 손동현;황범석
    • 응용통계연구
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    • 제36권2호
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    • pp.115-127
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    • 2023
  • 다항 프로빗 모형은 다중 분류와 선택 모형에서 흔히 사용하는 모형이다. 다항 프로빗 모형을 추정하기 위해 일반적으로 널리 사용하는 베이지안 접근법인 마르코프 연쇄 몬테카를로(MCMC) 방법은 계산 복잡도가 매우 높다는 문제점을 가지고 있다. 반면, 변분 베이즈 방법은 MCMC 방법보다 계산 복잡도는 낮으면서도 분류 성능적인 면에서 큰 차이가 나지 않아 더 효율적인 방법으로 알려져 있다. 본 연구에서는 가우시안 과정에 기반한 다항 프로빗 모형을 설명하고 해당 모형에 적용할 수 있는 변분 베이지안 근사법을 알아보고자 한다. 그리고 UCI에서 제공되는 쥐 단백질 발현 데이터에 가우시안 과정 분류에 대한 변분 베이지안 다항 프로빗 모형을 적용하여 그 성능을 확인하고 나이브 베이즈, K-최근접 이웃법, 서포트 벡터 머신 분류기의 성능과 비교한다.

수중글라이더용 항법필터 설계 (Design of Navigation Filter for Underwater Glider)

  • 유태석;차애리;박호규;김문환
    • 한국정보통신학회논문지
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    • 제26권12호
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    • pp.1890-1897
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    • 2022
  • 본 논문에서는 수중글라이더용 항법필터 설계를 수행한다. 해양의 염분, 수온 등 해양 정보 획득을 위해서 사용되는 수중글라이더는 저전력으로 장기간 운용이 되기 때문에, 다양한 센서를 적용하기에 많은 제약이 있다. 제한된 수중글라이더의 운용 특성을 고려하여 센서 구성이 다른 두 종류의 위치 추정을 위한 항법 필터를 설계한다. 항법필터는 최소한의 센서출력 정보를 바탕으로 수중글라이더의 동체좌표계 기준 속도를 추정한다. 첫 번째 필터의 센서 구성은 가속도계, 지자계, 심도계 센서로 구성 되어있고, 두 번째 필터는 첫 번째 필터와 동일한 구성에 자이로 센서가 추가된다. 추정된 속도는 자세정보와 융합하여 항법좌표계의 속도정보로 변환 뒤 최종적으로 위치를 추정한다. 제안된 필터의 성능을 분석하기 위해 단일 시뮬레이션 및 몬테카를로 수치해석 기법을 이용하여 분석을 수행하고 수행결과는 표준편차(standard deviation, 1σ)로 분석한다. 각 필터의 위치오차에 대한 표준편차는 334.34, 125.91m이다.

Rare Disaster Events, Growth Volatility, and Financial Liberalization: International Evidence

  • Bongseok Choi
    • Journal of Korea Trade
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    • 제27권2호
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    • pp.96-114
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    • 2023
  • Purpose - This paper elucidates a nexus between the occurrence of rare disaster events and the volatility of economic growth by distinguishing the likelihood of rare events from stochastic volatility. We provide new empirical facts based on a quarterly time series. In particular, we focus on the role of financial liberalization in spreading the economic crisis in developing countries. Design/methodology - We use quarterly data on consumption expenditure (real per capita consumption) from 44 countries, including advanced and developing countries, ending in the fourth quarter of 2020. We estimate the likelihood of rare event occurrences and stochastic volatility for countries using the Bayesian Markov chain Monte Carlo (MCMC) method developed by Barro and Jin (2021). We present our estimation results for the relationship between rare disaster events, stochastic volatility, and growth volatility. Findings - We find the global common disaster event, the COVID-19 pandemic, and thirteen country-specific disaster events. Consumption falls by about 7% on average in the first quarter of a disaster and by 4% in the long run. The occurrence of rare disaster events and the volatility of gross domestic product (GDP) growth are positively correlated (4.8%), whereas the rare events and GDP growth rate are negatively correlated (-12.1%). In particular, financial liberalization has played an important role in exacerbating the adverse impact of both rare disasters and financial market instability on growth volatility. Several case studies, including the case of South Korea, provide insights into the cause of major financial crises in small open developing countries, including the Asian currency crisis of 1998. Originality/value - This paper presents new empirical facts on the relationship between the occurrence of rare disaster events (or stochastic volatility) and growth volatility. Increasing data frequency allows for greater accuracy in assessing a country's specific risk. Our findings suggest that financial market and institutional stability can be vital for buffering against rare disaster shocks. It is necessary to preemptively strengthen the foundation for financial stability in developing countries and increase the quality of the information provided to markets.

몬테카를로 시뮬레이션을 이용한 지역빈도해석 기법의 성능 분석: 홍수지수법과 인공신경망 모델 (The assessment of performances of regional frequency models using Monte Carlo simulation: Index flood method and artificial neural network model)

  • 이주형;서미루;박재현;허준행
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2021년도 학술발표회
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    • pp.156-156
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    • 2021
  • 본 연구는 지역빈도해석을 기반으로한 인공신경망 모델과 기존에 널리 사용되는 방법인 홍수지수법의 성능을 몬테카를로 시뮬레이션을 이용하여 평가하였다. 컴퓨터 기술이 발달함에 따라 인공지능에 대한 접근성이 좋아지며 수문학을 포함한 다양한 분야에 적용되고 있다. 인공지능을 이용하여 강수량 및 유량 등 다양한 수문자료에 대한 예측이 이루어지고 있으나 빈도해석에 관한 연구는 비교적 적다. 본 연구에서 사용된 인공 지능 모델은 대상 지점의 지형학적 자료와 수문학적 자료를 이용하여 인공신경망을 통해 지점의 확률강우량(QRT-ANN) 및 확률분포형의 매개변수 (PRT-ANN)를 추정한다. 지형학적 자료로는 위도, 경도 그리고 고도가 사용되었으며 수문학적 자료로는 대상 지점의 최근 30년 일일연최대강우량을 사용하였다. 지역빈도해석의 정확도는 지역 내 통계적 특성이 비슷한 지점들이 포함되면 될수록 높아진다. 통계적 특성으로는 불일치 척도, 이질성 척도, 적합성 척도가 있으며 다양한 조건의 통계적 특성에 따른 세 개의 지역빈도해석 방법의 성능을 평가하고자 하였다. 대상 지역 내 n개의 지점이 있다고 가정하였을 때, 홍수지수법의 경우 n-1개의 지점으로 추정한 지역 성장곡선을 이용하여 나머지 1개 지점의 확률강우량을 산정할 수 있으며 인공신경망 모델들 또한 n-1개 지점들의 자료를 이용하여 모델을 구축한 뒤 나머지 지점의 확률강우량 및 확률분포형의 매개변수를 예측할 수 있다. PRT-ANN의 경우 예측된 매개변수를 이용하여 확률강우량을 산정하며 시뮬레이션 시행마다 발생시킨 자료의 지점빈도해석 결과에 대한 나머지 세 방법의 평균 제곱근 상대오차 (Relative root mean square error, RRMSE)를 계산하였다. 몬테카를로 시뮬레이션을 이용한 성능 분석을 통하여 관측값의 다양한 통계적 특성에 맞는 지역빈도해석 방법을 제시할 수 있을 것으로 판단된다.

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