• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.96-97
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• 2002

Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (SIP) are bioactive lysophospholipids (LPs) that act as mediators in various cellular processes, such as cell growth, differentiation, survival, motility, and cytoskeletal reorganization (1,2). LPA and S1P are both abundant in serum and are produced by activated platelets and other cell types. (omitted)

• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.353-353
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• 2006

Deoxyribonucelic acid (DNA) molecules have a huge molecular weight so that DNA was reported to be a promising natural polymer to give durable films. Among many applications of DNA, the authors focused their attention on separation membranes derived from DNA because membranes will play an important role in environmental and energy related processes. DNA-polyion complex membranes were prepared from DNA and corresponding polycations. The DNA-polyion complex membranes showed chiral separation ability toward racemic amino acid mixtures.

• BMB Reports
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• 제46권1호
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• pp.1-8
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• 2013

Phosphoinositides are the phosphorylated derivatives of phosphatidylinositol, and play a very significant role in a diverse range of signaling processes in eukaryotic cells. A number of phosphoinositide-metabolizing enzymes, including phosphoinositide-kinases and phosphatases are involved in the synthesis and degradation of these phospholipids. Recently, the function of various phosphatases in the phosphatidylinositol signaling pathway has been of great interest. In the present review we summarize the structural insights and biochemistry of various phosphatases in regulating phosphoinositide metabolism.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1993년도 제2회 신약개발 연구발표회 초록집
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• pp.33-33
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• 1993

Among the Glycosaminoglycans (GAGs), Heparin and its fractions or fragments, obtained by several different processes, are of considerable interest .In these last few years, the goal of the researchers in this field has been finding molecular species having selective action, like for instance species having only antithrombotic activity disjointed from any anticoagulant effect, and assessing the effects of these GAGs and of other GAGs, like dermatan sulphate, not only in the field of venous or arterial thrombosis but also on cell factors like smooth muscle cell proliferation and even on aspects of antiinflammatory activity.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1987년도 정기총회 및 창립40주년기념 학술대회 학회본부
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• pp.412-414
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• 1987

Theoretical studies of concentration for negative ion and neutral species in electrical excitation discharge have been conducted at $CO_2-N_2-He=1-7-12$, total pressure 20torr. With a computer model of neutral and negative ion processes we have calculated that the concentration of co was less than 20% when expected molecular.

• 대한화학회지
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• 제51권6호
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• pp.487-498
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• 2007

에너지 경관은 협동 과정이 일어나는 계에 대한 연구 방법으로, 액체, 유리, 분자 뭉치, 단백질 등 매우 다양한 대상들에 대한 이론적 연구 방법으로 이용되고 있다. 본 총설에서는 에너지 경관의 쓰임과 관련 실험에 관하여 간략히 살펴보았다.

• Genomics & Informatics
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• 제3권2호
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• pp.47-51
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• 2005

Molecular mechanisms of biological processes are typically represented as 'pathways' that have a graph­analogical network structure. However, due to the diversity of topics that pathways cover, their constituent biological entities are highly diverse and the semantics is embedded implicitly. The kinds of interactions that connect biological entities are likewise diverse. Consequently, how to model or process pathway data is not a trivial issue. In this review article, we give an overview of the challenges in pathway database development by taking the INOH project as an example.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2003년도 추계학술대회
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• pp.31-31
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• 2003

Magic technologies and smart biomarkers at the Omics Age！ This slogan is not only for the pharmaceutical companies as the speedy and cost-reduced development of global drug, but for all of the toxicologists and biologist. Biomarker refers to a variety of physiologic, pathologic, or anatomic measurements that are thought to relate to some aspect of normal or pathological processes (Temple 1995; Lesko and Atkinson 2001).(omitted)

• Molecules and Cells
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• 제42권10호
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• pp.687-692
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• 2019

Transfer RNA-derived small RNAs (tsRNAs) play a role in various cellular processes. Accumulating evidence has revealed that tsRNAs are deeply implicated in human diseases, such as various cancers and neurological disorders, suggesting that tsRNAs should be investigated to develop novel therapeutic intervention. tsRNAs provide more complexity to the physiological role of transfer RNAs by repressing or activating protein synthesis with distinct mechanisms. Here, we highlight the detailed mechanism of tsRNA-mediated dual regulation in protein synthesis and discuss the necessity of novel sequencing technology to learn more about tsRNAs.

• BMB Reports
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• 제52권1호
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• pp.3-4
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• 2019

Cellular senescence is defined as a state of stable cell cycle exit in response to various stimuli, which include both cytotoxic stress and physiological cues. In addition to the core non-proliferative aspect, senescence is associated with diverse functionalities, which contribute to the role of senescence in a wide range of pathological and physiological processes. Such functionality is often mediated by the capability of senescent cells to communicate with their surroundings. Emerging evidence suggests that senescence is not a single entity, but a dynamic and heterogeneous collective phenotype. Understanding the diverse nature of senescence should provide insights into the complexity of tissue homeostasis and its disruption, such as in aging and tumorigenesis.