• Journal of Broadcast Engineering
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• v.15 no.1
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• pp.14-28
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• 2010

This paper considers technological requirements to broadcast digital television signals using distributed frequency network (DFN) in the advanced television systems committee (ATSC) transmission system and proposes distributed translator (DTxR) to meet such requirements. In the DFN, DTxR uses different frequency from main transmitter, but same among DTxRs. In addition, this paper introduces digital signal processing (DSP) techniques, which consist of demodulation, equalization, transmitter identification (TxID) generation and insertion, and modulation, to implement DTxR.

• Journal of Satellite, Information and Communications
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• v.8 no.2
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• pp.88-93
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• 2013

The wideband chirp signal generator to enhance the resolution of synthetic aperture radar of obtaining the earth observation image is needed. This paper deals with designing, manufacturing and testing the wideband digital chirp signal generator having high resolution for LEO earth observation satellite. The wideband digital chirp signal generator is implemented with the memory-map based structure which is mostly applied in the satellite, and consists of the digital module to generate the digital chirp signal and the RF module to perform the quadrature modulation. The I/Q signals stored in the memory of the digital module are D/A converted and delivered to be quadrature modulated with the reference signal of 1275 MHz in the RF module. Furthermore, the test bench and GUI to validate the signal generator function are also developed. It is found that the requirement of 144 MHz bandwidth for the digital chirp signal generator is well met. Finally it is noteworthy that the distortion occurred in the chirp signal generator was compensated by the pre-distortion compensation.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2010.05a
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• pp.665-667
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• 2010

In this paper, the method to detect the IM(Inter Modulation) components of power amplifier is proposed by using frequency down-convertor. Output signals of power amplifier which is coupled by 20dB coupler and divided by power divider are applied to RF and LO of the frequency converter. It could be found the magnitude of IM components of power amplifier as a converted DC voltage which is come from the difference between 3th and 5th IM component. The detected DC voltage values are changed from 0.72V to 0.9V when 3rd IM component level changed from -26.4dBm to +2.15dBm and 5th IM component level changed from -34.2dBm to -12.89dBm as the Vgs of 3W power amplifier is changed.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.12 no.10
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• pp.1860-1865
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• 2008

40Gbps WDMSystems have been studied by numerical simulation to optimize their performance. Standard single mode fiber is assumed, and the most popular modulation format, NRZ, is used for the study. These assumptions are valid when existing WDM systems are required to upgrade their performance to 40Gbps. It is shown that the standard single mode fiber can transmit optical signals over 4800 (BER < 10-15) by optimizing optical and electrical filter characteristics at the receiver and by compensation of dispersion. In addition, when the system performance is mainly limited by ASE noise of EDFAs, it is found that flattop-shaped optical filter at the receiver gives a better result than Gaussian-shaped filter unless the insertion loss of the optical filter is larger than 5dB.

• Smart Structures and Systems
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• v.15 no.1
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• pp.135-150
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• 2015

Large concrete structures are prone to cracks and damages over time from human usage, weathers, and other environmental attacks such as flood, earthquakes, and hurricanes. The health of the concrete structures should be monitored regularly to ensure safety. A reliable method of real time communications can facilitate more frequent structural health monitoring (SHM) updates from hard to reach positions, enabling crack detections of embedded concrete structures as they occur to avoid catastrophic failures. By implementing an unconventional mode of communication that utilizes guided stress waves traveling along the concrete structure itself, we may be able to free structural health monitoring from costly (re-)installation of communication wires. In stress-wave communications, piezoelectric transducers can act as actuators and sensors to send and receive modulated signals carrying concrete status information. The new generation of lead zirconate titanate (PZT) based smart aggregates cause multipath propagation in the homogeneous concrete channel, which presents both an opportunity and a challenge for multiple sensors communication. We propose a time reversal based pulse position modulation (TR-PPM) communication for stress wave communication within the concrete structure to combat multipath channel dispersion. Experimental results demonstrate successful transmission and recovery of TR-PPM using stress waves. Compared with PPM, we can achieve higher data rate and longer link distance via TR-PPM. Furthermore, TR-PPM remains effective under low signal-to-noise (SNR) ratio. This work also lays the foundation for implementing multiple-input multiple-output (MIMO) stress wave communication networks in concrete channels.

• Proceedings of the Ginseng society Conference
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• 2002.10a
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• pp.531-544
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• 2002

Ginseng is the best known and most popular herbal medicine used worldwide. Ameliorating effects of ginseng were observed on the models of scopolamine-induced, aged or hippocampal lesioned learning and memory deficits. Further beneficial effects of ginseng were observed on neuronal cell death associated with ischemia or glutamate toxicity. In spite of these beneficial effects of ginseng on the CNS, little scientific evidence shows at the cellular level. In the present study, we have employed cultures of rat hippocampal neurons and examined the direct modulation of ginseng on NMDA receptor-induced changes in $[Ca^{2+}]_i$ and -gated currents using fura-2-based digital imaging and perforated whole-cell patch-clamp techniques, respectively. We found that ginseng total saponins inhibited NMDA-induced but less effectively glutamate-induced increase in $[Ca^{2+}]_i$ Ginseng total saponins also modulated $Ca^{2+}$ transients evoked by depolarization with 50 mM KCI along with its own effects on $[Ca^{2+}]_i$. Among ginsenosides tested, ginsenoside $Rg_3$ was found to be the most potent component for ginseng actions on NMDA receptors. Furthermore, we examined the inhibitory effects ofbiotransformants of ginsenosides on NMDA receptor using purified stereoisomers of ginsenosides. 20(S)-ginsenoside $Rg_3$ and its metabolite, 20(S)-ginsenoside $Rh_3$, produced the strongest inhibition while 20(S)-ginsenoside $Rh_1$ and Compound K produced the moderate inhibition on NMDA-induced increase in $[Ca^{2+}]_i$. The data obtained suggest that the inhibition of NMDA receptors by ginseng, in particular by 20(S)-ginsenoside $Rg_3$ and its metabolite, 20(S)-ginsenoside $Rh_2$, could be one of mechanisms for ginsengmediated neuroprotective actions.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.8
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• pp.2900-2922
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• 2021

In this paper, the power spectral density(PSD) for Multilevel Minimum Shift Keyed signal with modulation index h = 1/2 (M-ary MSK) are derived using the mathematical method of the Markov Chain model. At first, according to an essential requirement of the phase continuity characteristics of MSK signals, a complete model of the whole process of signal generation is built. Then, the derivations for autocorrelation functions are carried out precisely. After that, we verified the correctness and accuracy of the theoretical derivation by comparing the derived results with numerical simulations using MATLAB. We also divided the spectrum into four components according to the derivation. By analyzing these figures in the graphic, each component determines the characteristics of the spectrum. It is vital for enhanced spectral characteristics. To more visually represent the energy concentration of the main flap and the roll-down speed of the side flap, the specific out-of-band power of M-ary MSK is given. OMLCD(Optimum Maximum Likelihood Coherent Detection) of M-ary MSK is adopted to compare the signal received with prepared in advance in a code element T to go for the best. And M-ary MSK BER(Bit Error Rate) is compared with the same ary PSK (Phase Shift Keying) with M=2,4,6,8. The results show the detection method could improve performance by increasing the length of L(memory inherent) in the phase continuity.

• Journal of Neurogastroenterology and Motility
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• v.24 no.4
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• pp.512-527
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• 2018

This review provides a comprehensive overview of brain imaging studies of the brain-gut interaction in functional gastrointestinal disorders (FGIDs). Functional neuroimaging studies during gut stimulation have shown enhanced brain responses in regions related to sensory processing of the homeostatic condition of the gut (homeostatic afferent) and responses to salience stimuli (salience network), as well as increased and decreased brain activity in the emotional response areas and reduced activation in areas associated with the top-down modulation of visceral afferent signals. Altered central regulation of the endocrine and autonomic nervous responses, the key mediators of the brain-gut axis, has been demonstrated. Studies using resting-state functional magnetic resonance imaging reported abnormal local and global connectivity in the areas related to pain processing and the default mode network (a physiological baseline of brain activity at rest associated with self-awareness and memory) in FGIDs. Structural imaging with brain morphometry and diffusion imaging demonstrated altered gray- and white-matter structures in areas that also showed changes in functional imaging studies, although this requires replication. Molecular imaging by magnetic resonance spectroscopy and positron emission tomography in FGIDs remains relatively sparse. Progress using analytical methods such as machine learning algorithms may shift neuroimaging studies from brain mapping to predicting clinical outcomes. Because several factors contribute to the pathophysiology of FGIDs and because its population is quite heterogeneous, a new model is needed in future studies to assess the importance of the factors and brain functions that are responsible for an optimal homeostatic state.

• Molecules and Cells
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• v.42 no.2
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• pp.123-134
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• 2019

Lysophosphatidic acid (LPA) is an endogenous lysophospholipid with signaling properties outside of the cell and it signals through specific G protein-coupled receptors, known as $LPA_{1-6}$. For one of its receptors, $LPA_1$ (gene name Lpar1), details on the cis-acting elements for transcriptional control have not been defined. Using 5'RACE analysis, we report the identification of an alternative transcription start site of mouse Lpar1 and characterize approximately 3,500 bp of non-coding flanking sequence 5' of mouse Lpar1 gene for promoter activity. Transient transfection of cells derived from mouse neocortical neuroblasts with constructs from the 5' regions of mouse Lpar1 gene revealed the region between -248 to +225 serving as the basal promoter for Lpar1. This region also lacks a TATA box. For the region between -761 to -248, a negative regulatory element affected the basal expression of Lpar1. This region has three E-box sequences and mutagenesis of these E-boxes, followed by transient expression, demonstrated that two of the E-boxes act as negative modulators of Lpar1. One of these E-box sequences bound the HeLa E-box binding protein (HEB), and modulation of HEB levels in the transfected cells regulated the transcription of the reporter gene. Based on our data, we propose that HEB may be required for a proper regulation of Lpar1 expression in the embryonic neocortical neuroblast cells and to affect its function in both normal brain development and disease settings.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.7
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• pp.807-815
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• 2019

In this paper, we design a power amplifier to support quad-band in wireless communication devices using RF CMOS 180-nm process. The proposed power amplifier consists of low-band 0.9, 1.8, and 2.4 GHz and high-band 5 GHz. We proposed a structure that can support each input matching network without using a switch. For maximum linear output power, the output matching network was designed for impedance conversion to the power matching point. The fabricated quad-band power amplifier was verified using modulation signals. The long-term evolution(LTE) 10 MHz modulated signal was used for 0.9 and 1.8 GHz, and the measured output power is 23.55 and 24.23 dBm, respectively. The LTE 20 MHz modulated signal was used for 1.8 GHz, and the measured output power is 22.24 dBm. The wireless local area network(WLAN) 802.11n modulated signal was used for 2.4 GHz and 5.0 GHz. We obtain maximum linear output power of 20.58 dBm at 2.4 GHz and 17.7 dBm at 5.0 GHz.