• Title/Summary/Keyword: mixture 모델

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Effect of Mixture of Atractylodes macrocephala and Amomum villosum Extracts on Body Weight and Lipid Metabolism in High Fat Diet-Induced Obesity Model (고지방식이 유도 비만 모델에서 백출과 사인 추출 혼합물이 체중 및 지질대사에 미치는 영향)

  • Kim, Ha Rim;Kwon, Yong Kwan;Choi, Bong Keun;Jung, Hyun Jong;Baek, Dong Gi
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.34 no.2
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    • pp.75-80
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    • 2020
  • In this study, we investigated the dose-dependent effects of mixtures of Atractylodes macrocephala (AM) and Amomum villosum (AV) water extracts in a ratio of 3:1 on high fat diet (HFD)-induced obesity model. Oral administration of various concentrations with mixtures of AM and AV extracts in a ratio of 3:1 for 6 weeks inhibited HFD-induced increases of body, liver and epididymal fat weights in a dose-dependent fashions. Those effects may be mediated by decreased expressions of lipogenesis-related genes such as acetyl coA carboxylase (ACC) and fatty acid synthase (FAS) in liver. Also, increase of insulin and decrease of adiponectin in serum by HFD supply were inhibited by three different dosages of mixtures of AM and AV extracts in a ratio of 3:1. HFD supply induced increases of serum total cholesterol, triglyceride and LDL cholesterol. However, hyperlipidemia was significantly decreased in dose-dependent manners by treatment with mixtures of AM and AV extracts. Based on the results of the present study, hypolipidemic and anti-obesity effects by mixtures of AM and AV extracts were found in HFD-induced obesity model. Further clinical investigation is needed to develop anti-obesity therapeutic or preventive agents by using mixtures of AM and AV extracts.

Calculation of the Absorption Coefficient and Weighting Factor Expressing the Total Emissivity of Flame (화염의 총괄폭사 계수를 나타내는 급수계수 및 가중치의 계산)

  • 하만영;허병기
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.10 no.1
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    • pp.121-130
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    • 1986
  • Using the sbsorption coefficients and the weighting factors of the gray gas, the total emissivities of C $O_{2}$- $H_{2}$O and C $O_{2}$- $H_{2}$O- transient species-soot gas mixtures can be expressed by the following equation, [a numerical formula] Where, $a_{i}$ and $K_{i}$ represent the weighting factor and the absorption coeffient of i-gray gas respectively; L is the pathlength of the gas. This equation is widely used for the analyses of the radiation heat transfer in the combustors of internal combustion engines and in the furnace of external combustion engines. In this work, a simple calculation model of the weighting factor and the absorption coeffient of the above equation was developed. The weighting factors and the absorption coefficients of combustion products were calculated by applying the model to various kinds of fossil fuels such as coal and heavy oil. Then, the computed total emissivities for each fuel and pathlength were compared with measured and calculated values which have been already published in the literatures. The followings were the results obtained through the comparisons between the calculated emissivites and the published values; the developed model for the calculations of the weighting factor and the absorption coefficient of C $O_{2}$- $H_{2}$O and C $O_{2}$- $H_{2}$O- transient species-soot gas mixtures could be applied over the wide ranges of the temperature and the pathlength; the errors between the total emissivities calculted and the values published were maximum 10%, and average 1%, respectively.

Development and Evaluation of Accelerated Reflection Cracking Test System in Shear Mode (전단 반사균열 모사 실험방법 개발 및 적용성 연구)

  • Kim, Kwang-Woo;Yim, Sung-Bin;Doh, Young-Soo;Rhee, Suk-Keun
    • International Journal of Highway Engineering
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    • v.1 no.1
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    • pp.97-106
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    • 1999
  • This study was conducted to develop a test system for evaluating resistance against reflection cracking in shear mode caused by wheel load in asphalt concrete overlaid on the deteriorated cement concrete pavement. Reflection cracking resistance of selected polymer modified asphalt(PMA) mixtures with and without reinforcement was evaluated using this test system. It was shown that the test results accounted for the effectiveness of materials and reinforcement characteristics in terms of the difference in the resistance against reflection cracking. A shear failure life of a certain mixture was estimated with a high coefficient of determination. when the test results were used in a well known prediction model. Therefore, it seemed to be possible to use this technique for predicting a relative service life of on overlay.

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Real Time Abandoned and Removed Objects Detection System (실시간 방치 및 제거 객체 검출 시스템)

  • Jeong, Cheol-Jun;Ahn, Tae-Ki;Park, Jong-Hwa;Park, Goo-Man
    • Journal of Broadcast Engineering
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    • v.16 no.3
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    • pp.462-470
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    • 2011
  • We proposed a realtime object tracking system that detects the abandoned or disappeared objects. Because these events are caused by human, we used the tracking based algorithm. After the background subtraction by Gaussian mixture model, the shadow removal is applied for accurate object detection. The static object is classified as either of abandoned objects or disappeared object. We assigned monitoring time to the static object to overcome a situation that it is being overlapped by other object. We obtained more accurate detection by using region growing method. We implemented our algorithm by DSP processor and obtained an excellent result throughout the experiment.

Anti-Inflammatory Effects of Prunus mume Mixture in Colitis Induced by Dextran Sodium Sulfate (매실 혼합물이 DSS로 유도된 염증성 장질환 동물모델의 면역조절에 미치는 활성)

  • Jin, Hai-Lan;Lee, Bo-Ram;Lim, Kyung-Jik;Debnath, Trishna;Shin, Heung-Mook;Lim, Beong-Ou
    • Korean Journal of Medicinal Crop Science
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    • v.19 no.1
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    • pp.16-23
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    • 2011
  • This study was conducted to investigate the anti-inflammatory effects of Pruns mume, Schisandra chinensis, Chaenomeles sinensis-- Prunus mume mixtrue (PM) treatment on colitis induced in mice by dextran sodium sulfate (DSS) treatment. A total of 25 male BALB/c mice (average weight $20.7\;{\pm}\; 1.6 \;g$) were divided into 5 treatment groups and fed a commercial diet (A), PM administration (B), commercial diet + induced colitis by DSS (C), PM administration + induced colitis by DSS (D) and sulfasalazine + induced colitis by DSS (E). We found that PM treatment (D) and sulfasalazine (E) decreased the expression of $TNF-{\alpha}$ and COX-2 compared to the DSS-induced colitis group (C). The expression of IL-4, STAT6, $IFN-{\gamma}$, STAT1 was decreased in group D and group E compared to the colitis group (C), COX-2 and STAT1 were more decreased in group D. The serum IgE levels decreased in the PM treatment groups (C and D) compared to the non-PM treatment groups (A and B) although there was no significant difference between the PM treatment groups. It is notable that a therapeutic application of the PM extracts ameliorated DSS-induced colitis in mice.

Hydrogen Separation from Binary and Ternary Mixture Gases by Pressure Swing Adsorption (PSA 공정에 의한 이성분 및 삼성분 혼합기체로부터 수소분리)

  • Kang, Seok-Hyun;Jeong, Byung-Man;Choi, Hyun-Woo;Ahn, Eui-Sub;Jang, Seong-Cheol;Kim, Sung-Hyun;Lee, Byung-Kwon;Choi, Dae-Ki
    • Korean Chemical Engineering Research
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    • v.43 no.6
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    • pp.728-739
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    • 2005
  • An experiment and simulation were performed for hydrogen separation of mixtures by PSA (pressure swing adsorption) process on activated carbon. The binary ($H_2/Ar$; 80%/ 20%) and ternary ($H_2/Ar/CH_4$; 60%/ 20%/ 20%) mixtures were used to study the effects of feed composition. The cyclic performances such as purity, recovery, and productivity of 2bed-6step PSA process were experimentally and theoretically compared under non-isothermal and non-adiabatic conditions. The develped process produced the hydrogen with 99% purity and 75% recovery from both processes. Therefore, optimal separation condition was referred multicomponent gas mixtures.

A Study on Lip Detection based on Eye Localization for Visual Speech Recognition in Mobile Environment (모바일 환경에서의 시각 음성인식을 위한 눈 정위 기반 입술 탐지에 대한 연구)

  • Gyu, Song-Min;Pham, Thanh Trung;Kim, Jin-Young;Taek, Hwang-Sung
    • Journal of the Korean Institute of Intelligent Systems
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    • v.19 no.4
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    • pp.478-484
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    • 2009
  • Automatic speech recognition(ASR) is attractive technique in trend these day that seek convenient life. Although many approaches have been proposed for ASR but the performance is still not good in noisy environment. Now-a-days in the state of art in speech recognition, ASR uses not only the audio information but also the visual information. In this paper, We present a novel lip detection method for visual speech recognition in mobile environment. In order to apply visual information to speech recognition, we need to extract exact lip regions. Because eye-detection is more easy than lip-detection, we firstly detect positions of left and right eyes, then locate lip region roughly. After that we apply K-means clustering technique to devide that region into groups, than two lip corners and lip center are detected by choosing biggest one among clustered groups. Finally, we have shown the effectiveness of the proposed method through the experiments based on samsung AVSR database.

Solidification of Hazardous Wastes from Electroplating Industry (도금공장 유해폐기물의 고형화에 관한 연구)

  • Shin, Hang Sik;Her, Nam Ryoung;Koo, Ja Kong
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.8 no.2
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    • pp.89-98
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    • 1988
  • This research evaluated factors on cement-based solidification process designed for hazardous sludge produced from electroplating industry. Four factors of sand/cement ratio, water/cement ratio, amount of wet sludge and amount of a precipitator, were investigated in terms of leachability and compressive strength of the solidified materials. Results of triplicate tests and statistical analysis indicated that sand/cement ratio(S/C) had the greatest effect on leaching of Cr(VI) from the solidified materials while water/cement ratio(W/C) on Zn and compressive strength. Cr(VI) was fixed better than Zn by portland cement. An experimental modeing was developed to estimate leached metal concentration and compressive strength at a given condition. Proper mixing criteria were also suggested for the use of the solidified mixture as construction materials. In solidification of 30g dry sludge, optimal condition was studied for S/C ratio, W/C ratio and the weight of precipitator which were 1, 1.5 and 1.075g respectively.

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Bayesian Clustering of Prostate Cancer Patients by Using a Latent Class Poisson Model (잠재그룹 포아송 모형을 이용한 전립선암 환자의 베이지안 그룹화)

  • Oh Man-Suk
    • The Korean Journal of Applied Statistics
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    • v.18 no.1
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    • pp.1-13
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    • 2005
  • Latent Class model has been considered recently by many researchers and practitioners as a tool for identifying heterogeneous segments or groups in a population, and grouping objects into the segments. In this paper we consider data on prostate cancer patients from Korean National Cancer Institute and propose a method for grouping prostate cancer patients by using latent class Poisson model. A Bayesian approach equipped with a Markov chain Monte Carlo method is used to overcome the limit of classical likelihood approaches. Advantages of the proposed Bayesian method are easy estimation of parameters with their standard errors, segmentation of objects into groups, and provision of uncertainty measures for the segmentation. In addition, we provide a method to determine an appropriate number of segments for the given data so that the method automatically chooses the number of segments and partitions objects into heterogeneous segments.

Numerical Analysis of Effect of Inhomogeneous Pre-mixture on Pressure Rise Rate in HCCI Engine by Using Multizone Chemical Kinetics (화학반응수치해석을 이용한 HCCI기관의 예혼합기의 성층화성이 연소시의 압력 상승률에 미치는 영향)

  • Lim, Ock-Taeck
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.34 no.5
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    • pp.449-456
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    • 2010
  • The HCCI engine is a prospective internal combustion engine with which high diesel-like efficiencies and very low NOx and particulate emissions can be achieved. However, several technical issues must be resolved before HCCI engines can be used for different applications. One of the issues concerning the HCCI engine is that the operating range of this engine is limited by the rapid pressure rise caused by the release of excessive heat. This heat release is because of the self-accelerated combustion reaction occurring in the engine and the resulting engine knock in the high-load region. The purpose of this study is to evaluate the role of thermal stratification and fuel stratification in reducing the pressure rise rate in an HCCI engine. The concentrations of NOx and CO in the exhaust gas are also evaluated to confirm combustion completeness and NOx emission. The computation is carried out with the help of a multizone code, by using the information on the detailed chemical kinetics and the effect of thermal and fuel stratification on the onset of ignition and rate of combustion. The engine is fueled with dimethyl ether (DME), which allows heat release to occur in two stages, as opposed to methane, which allows for heat release in a single stage.