• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.5773-5777
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• 2015

Background: Oral squamous cell carcinoma (OSCC) is thought to develop from precancerous dysplastic lesions through multistep processes of carcinogenesis involving activation of oncogenes and loss of tumor suppressor genes. The human epidermal growth factor receptor 2 (Her-2/neu [erbB-2]), a cell membrane glycoprotein, is a growth factor receptor that has receptor tyrosine kinase activity. Her2/neu activation plays a central role in cell proliferation and survival. It has been shown that overexpression of Her2/neu increases the rate of cell division and growth, leading to precancerous changes. The aim of the present study was to compare the serum and salivary Her2/neu levels between cases with premalignant and malignant oral lesions. Materials and Methods: Fasting blood samples and unstimulated saliva by passive drooling were collected from three groups of healthy control (n=20), premalignant disorder (PMD) (n=20) and OSCC (n=25) subjects. The HER2 extracellular domain (HER2 ECD) levels were measured using ELISA. Results: The levels of serum Her2/neu showed no significant differences between any of the groups but on the other hand salivary Her2/neu levels were found to be significantly (p<0.05) higher when compared between control (median 68.7 pg/ml, range: 21.5 - 75.8) and OSCC (median 145.6 pg/ml, range: 45.1-191.1). A similar trend was observed when comparing between PMD (median 43.3, range: 22.1 -94.7) and OSCC with a statistical significance of p<0.05. Conclusions: Our study provided evidence of increased salivary Her2/neu in OSCC when compared to PMD and control which was not the case for serum levels. This suggests that probably Her2/neu is not highly amplified as in breast cancer so as to be reflected in serum. Since saliva is in local vicinity of the OSCC, even a mild increase might be mirrored. On the whole, this study proposes Her2/neu as marker for distinguishing premalignant and malignant conditions.

• Aerospace Engineering and Technology
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• v.4 no.1
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• pp.57-65
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• 2005

Due to the future of a large size satellite like Geo-stationary orbit satellite, KARI has progressed the construction of Large Thermal Vacuum Chamber(LTVC) with Φ8mXL10m, which simulates the orbit environment at space. The space environment can be characterized as very harsh conditions. Once the spacecraft is launched and enters its orbit, the satellite is exposed to this space environment. The continuous exposure to such space environment could cause malfunction of major parts of the spacecraft, which could lead to the failure of the entire mission. Due to the fact that space environment is completely different from that of the ground, the satellite that functioned normally on the ground could show some unexpected malfunction in space environment. For this reason, the performance of the spacecraft must be confirmed under the simulated conditions of the space environment. This document includes LTVC control logic, Interlock by which the LTVC can be controlled more safely and efficiently.

• Journal of the Korea Institute of Military Science and Technology
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• v.16 no.2
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• pp.160-168
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• 2013

In tactical environment, tactical wireless networks are generally comprised of Tactical MANETs(T-MANETs) or Tactical WMNs(T-WMNs). The most important services in tactical network are voice and low rate data such as command control and situation awareness. These data should be forwarded via multi-hop in tactical wireless networks. Urgent and mission-critical data should be protected in this environment, so QoS(Quality of Service) must be guaranteed for specific type of traffic for satisfying the requirement of a user. In IEEE 802.11s, TDMA-based MAC protocol, MCCA(MCF Controlled Channel Access), has a function of resource reservation. But 802.11s protocol can not guarantee the end-to-end QoS, because it only supports reservation with neighbors. In this paper, we propose the routing protocol, R-HWMP(Reservation-based HWMP) which has the resource reservation to support the end-to-end QoS. The proposed protocol can reserve the channel slots and find optimal path in T-WMNs. We analyzed the performance of the proposed protocol and showed that end-to-end QoS is guaranteed using NS-2 simulation.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.23 no.2
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• pp.196-206
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• 2012

AESA radar is able to instantaneously and adaptively position and control the beam, and such adaptive beam pointing of AESA radar enables to remarkably improve the multi-mission capability, compared with mechanically scanned array radar. AESA radar brings a new challenges, radar resource management(RRM), which is a technique efficiently allocating finite resources, such as energy and time to each task in an optimal and intelligent way. Especially radar beam scheduling is the most critical component for the success of RRM. In this paper, we proposed stochastic radar beam scheduling algorithm using simulated annealing(SA), and evaluated the performance on the multi-function radar scenario. As a result, we showed that our proposed algorithm is superior to previous dispatching rule based scheduling algorithm from the viewpoint of beam processing latency and the number of scheduled beams, with real time capability.

• Journal of Aerospace System Engineering
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• v.14 no.5
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• pp.83-90
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• 2020

Disasters are causing significant damage to the lives and property of our society and are recognized as social problems that need to be solved nationally and globally. The 4th industrial revolution technologies affecting society as a whole such as the Internet of Things(IoT), Artificial Intelligence(AI), Drones(Unmanned Aerial Vehicles), and Big Data are continuously absorbed into the disaster and safety industries as scientific and technological tools for solving social problems. Very soon, twenty-nine domestic UAV-related organizations/companies will complete the construction of a multicopter type small UAV integrated system ('17~'20) that can be operated at disaster and security sites. The current work considers and proposes the mid-to-long term R&D direction of disaster UAV as a strategic asset of the national disaster response system. First, the trends of disaster and safety industry and policy are analyzed. Subsequently, the development status and future plans of small UAV, securing shortage technology, and strengthening competitiveness are analyzed. Finally, step-by-step R&D direction of disaster UAV in terms of development strategy, specialized mission, platform, communication, and control and operation is proposed.

• Ocean and Polar Research
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• v.42 no.2
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• pp.171-178
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• 2020

R/V EARDO, commissioned in 1992, has successfully carried out ocean research campaigns in Korean jurisdictional and adjacent waters, including continental margins and coastal zones within the Korean Exclusive Economic Zone (EEZ), for 29 years. However, it will soon be reaching the end of its useful service life. A replacement for R/V EARDO is urgently needed to ensure the safety of vessel itself and its crews, and efficient ship operation and maintenance, as well as to meet modern scientific mission requirements (SMRs). Basic specifications for a replacement ship have been devised and reviewed over the past nine months. A test of the proposed hull form was also performed. The total tonnage of the proposed vessel is approximately 740 tons, and the overall length and width are 62.0 and 11.6 m, respectively. The new ship will thus be 73% larger than the current R/V EARDO; in particular, the research workspace will be 4.4 times larger. The major design priorities are the propulsion system, efficiency of radiated noise and vibration control, and the dynamic positioning system. An environmentally friendly emission system, meeting International Maritime Organization (IMO) Tier III regulations, will be installed in the third exhaust pipe. Various wet and dry lab spaces as well as 32 different scientific instruments have also been considered in the ship design.

• Journal of Digital Convergence
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• v.14 no.10
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• pp.173-181
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• 2016

The objective of this study is to subdivide the tactical considerations (METT+TC; Mission, Enemy, Terrain & Weather, Troops available, Time available, Civil considerations) through Delphi method and prioritize those via AHP (Analytic Hierarchy Process). Though it has been taken for granted that the tactical considerations were inevitable for decision making relating to military operations, their segmentation and priority have not been studied sufficiently in military. The data for Delphi method and AHP were based on interview with military experts and questionnaires answered by those. Six tactical considerations were segmented into 34 sub-considerations by Delphi, and Six tactical considerations and 34 sub-ones were prioritized through AHP in attack and defense aspects. If the research results will be embedded into database of automatic command and control system (e.g. ACTIS; Army Tactical Command Information System), effective decision-making process will get easier and faster.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.44 no.2
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• pp.123-130
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• 2016

This paper describes the design and implementation scheme of HTS(Helmet Tracking System) providing coincident LOS(Line of Sight) between aircraft and HMD(Helmet Mounted Display) which displays flight and mission information on Pilot helmet. The functionality and performance of HMD system depends on the performance of helmet tracking system. The target of HTS system design is to meet real-time performance and reliability by predicting non-periodic latency and high accuracy performance. To prove an availability of a proposed approach, a robust hybrid scheme with a fusion optical and inertial tracking system are tested through a implemented test-bed. Experimental results show real-time and reliable tracking control in spite of external errors.

• Aerospace Engineering and Technology
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• v.9 no.2
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• pp.14-21
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• 2010

Ion thruster is a kind of electrostatic thruster that use electrostatic field in order to accelerate ionized propellant. Ion thruster have characteristics of small thrust but very high specific impulse among the electric thrusters. High specific impulse can reduce propellant consumption significantly. So, ion thruster have advantage for long time and long distance mission. Recently, plans for space exploration is increasing gradually not only at traditional forward countries for space like USA, Russia and Europe, but also other countries like Japan, China and India. Exploration for superior planets and asteroids the propellant ratio can go up to about 99% when chemical propulsion is used as a cruising thruster. Therefore, latest space exploration vehicles use the ion thruster as main thruster for del-V burn and use monopropellant thrusters for attitude control. In this paper, the development process of preliminary ECR ion thruster and the ECR discharge test results will be presented.

• The Korean Journal of Air & Space Law and Policy
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• v.12
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• pp.210-245
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• 2000

This study is to review the problem concerned with aviation safety in Korea and suggest the solution to secure the aviation safety, in respect of regulation. At first, the definition and characteristics of aviation safety are studied, and then the endeavor for the aviation safety of ICAO and FAA are reviewed. All the fields of aviation safety area are included in the scope of this study; airworthiness in aircraft production and maintenance, flight operation, airport operation and air traffic control. The level of safety can be estimated by the frequency of accidents and seriousness. The causes of air accidents can be summarized as five factors; human factor, traffic environment. aircraft, weather, and unexpected incident. The activities to protect accidents are also can be summarized as five areas; man, machine, medium, mission and management. ICAO established the standards and recommends for the aviation safety, and adopted strategic action plan for 21st century. Federal Aviation Administration of USA also contributes for the aviation safety of world wide. Nowadays, ICAO and FAA tries to coordinate each other to set up efficient and effective ways for the aviation safety. ICAO developed safety oversight manual and FAA developed model regulations, individually. However, there has been trials to merge the results of each institute's studies. The direction of this endeavor is to meet the new environment related to globalization of air transport industry. It is necessary for our government to improve the aviation safety regulation system to address the new wave of aviation safety system pursued by international organization. A systematic and comprehensive measure should be devised by cooperation of all the related field and area.