• Title/Summary/Keyword: minimal disc

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Antimicrobial and Antioxidative Activities of Solvent Fractions of Quercus mongolica Leaf (신갈나무 잎의 용매분획별 항균 및 항산화 효과)

  • 오덕환;공영준;강태수;이명기;박부길
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.2
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    • pp.338-343
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    • 2001
  • The ethanol extract of Quercus mongolica leaf was fractionated by various organic solvents, and their antimicrobial and antioxidative activities were investigated against several microorganisms. The ethanol extract of Quercus mongolica leaf at two thousand $\mu\textrm{g}$ per disc showed 17~21mm inhibition zone against Gram postive and Gram negative bacteria. Among the various solvent fractions from ethanol extract of Quercus mongolica leaf, the hexane fraction showed the strongest antimicrobial activity. Minimal inhibitory concentration (MIC) of hexane fraction was 250$\mu\textrm{g}$/mL against Bacillus cereus, 250~500$\mu\textrm{g}$/mL against Listeria monocytogenes, 500$\mu\textrm{g}$/mL against Staphylococcus aureus, Salmonella typhimurium, Escherichia coli O157, and Pseudomonas aeruginosa. Also, the hexane and chloroform fraction had the similar antioxidative activity compared to that of butylated hydroxy toluene(BHT).

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Anticariogenic Activity of Callistemon citrinus Extract against Streptococcus mutans

  • Park, Youngki;Lee, Wi Young;Park, So-Young;Ahn, Jin Kwon;Han, Mu-Seok
    • Journal of the Korean Wood Science and Technology
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    • v.33 no.2 s.130
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    • pp.72-77
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    • 2005
  • Streptococcus mutans is known as a strong cariogenic bacterium and produces dental caries. This study was carried out to develop anticariogenic agents from Callistemon citrinus. Crude extracts and thier various solvent fractions of the plant extracts were tested for the antibacterial activity against S. mutans. The anticariogenic activity was evaluated with by paper disc diffusion method and minimal inhibition concentration (MIC). The extract from the fruit and its hexane fraction showed a strong inhibitory effect on the growth of S. mutans and the MICs were 31.2 and $3.9{\mu}g/m{\ell}$, respectively.

Antibacterial Activities of Zedoariae Rhizoma against the Streptococcus Mutans (아출의 치아우식균에 대한 항균활성)

  • Jeon, Hoon;Yoo, Dal-San;Seo, Jin-Joo;Hong, Jong-Ki;Choo, Ji-Yeon;Kang, In-Tak;Park, Yeong-Seo;Lim, Jong-Pil
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.5
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    • pp.1245-1248
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    • 2006
  • In order to investigate antibacterial activities of Zedoariae Rhizoma against Streptococcus mutans ATCC27351, paper disc test, minimal inhibitory concentration (MIC) test and pH check were carried out. The 80% ethanol extract of Zedoariae Rhizoma(ZXE) showed significant activity. The MIC of ZXE was 25.0mg/ml.

NOTE ON CONTACT STRUCTURE AND SYMPLECTIC STRUCTURE

  • Cho, Mi-Sung;Cho, Yong-Seung
    • Bulletin of the Korean Mathematical Society
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    • v.37 no.1
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    • pp.181-189
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    • 2000
  • Let (X, J) be a closed, connected almost complex four-manifold. Let $X_1$ be the complement of an open disc in X and let ${\varepsilon}_1$be the contact structure on the boundary ${\varepsilon}X_1$ which is compatible with a symplectic structure on $X_1$, Then we show that (X, J) is symplectic if and only if the contact structure ${\varepsilon}_1$ on ${\varepsilon}X_1$ is isomorphic to the standard contact structure on the 3-sphere $S^3$ and ${\varepsilon}X_1$is J-concave. Also we show that there is a contact structure ${\varepsilon}_0\ on\ S^2\times\ S^1$which is not strongly symplectically fillable but symplectically fillable, and that $(S^2{\times}S^1,\;{\varepsilon})$ has infinitely many non-diffeomorphic minimal fillings whose restrictions on$\S^2\times\ S^1$are ${\sigma}$ where ${\sigma}$ is the restriction of the standard symplectic structure on $S^2{\times}D^2$.

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Performance Comparison of Deep Learning Model Loss Function for Scaffold Defect Detection (인공지지체 불량 검출을 위한 딥러닝 모델 손실 함수의 성능 비교)

  • Song Yeon Lee;Yong Jeong Huh
    • Journal of the Semiconductor & Display Technology
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    • v.22 no.2
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    • pp.40-44
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    • 2023
  • The defect detection based on deep learning requires minimal loss and high accuracy to pinpoint product defects. In this paper, we confirm the loss rate of deep learning training based on disc-shaped artificial scaffold images. It is intended to compare the performance of Cross-Entropy functions used in object detection algorithms. The model was constructed using normal, defective artificial scaffold images and category cross entropy and sparse category cross entropy. The data was repeatedly learned five times using each loss function. The average loss rate, average accuracy, final loss rate, and final accuracy according to the loss function were confirmed.

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Solubility, Antioxidative and Antimicrobial Activity of Chitosan-Ascorbate (키토산-아스코베이트의 용해성, 항산화성 및 항균성)

  • Lee, Seung-Bae;Lee, Ye-Kyung;Kim, Soon-Dong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.8
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    • pp.973-978
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    • 2006
  • This study was conducted to investigate the solubility, antioxidative and antimicrobial activity of the freeze dried chitosan-ascorbate (CAs) and chitosan-acetate (CAc). In the results of solubility, CAs was soluble over 0.5% in distilled water, vinegar, green tea, soju (distilled liquor), beer and red wine, while it was not soluble in soy sauce, soy milk, milk, orange juice, coffee, sesame oil, soy milk and soybean oil. The solubility of CAc in the liquid foods was similar to those of CAs, but it was soluble less than 0.1% in beer, and formed curd in red wine. Electron donating activity, antioxidative activity and SOD activity of CAs were 48.2, 90.6 and 67.5%, respectively, while the activities of the CAc were 0, 40.0 and 10.0%, respectively. The minimal inhibitory concentrations of CAs and CAc were $200\;{\mu}g/disc$ against Bacillus circulans, Bacillus brevis, Bacillus licheniformis, Bacillus arabitane and Bacillus sterothermophillus, $400\;{\mu}g/disc$ against Escherichia coli O157, Listeria monocytogenous, Bacillus cereus and Bacillus subtilis. There was no significant difference in Hunter's L* value between CAs and CAc $(81.95{\sim}82.97)$, but Hunter's a* and b* values of the CAs was higher than those of CAc. While sour and bitter tastes of CAs were lower than those of CAc, there was no significant difference in astringent taste. From these results, it suggested that CAs has more extensive utility in liquid foods with antimicrobial and antioxidant activity as well as sensory quality compared to CAc.

Antibiotic susceptibility of Porphyromonas gingivalis and Prevotella intennedia from the Patients with Adult Periodontitis (성인성 치주염환자에서 분리한 Porphyromonas gingivalis와 Prevotella intennedia의 항생제 내성에 관한 연구)

  • Kim, Heung-Shik;You, Hyung-Keun;Shin, Hyung-Shik
    • Journal of Periodontal and Implant Science
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    • v.26 no.3
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    • pp.625-639
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    • 1996
  • The purpose of this study was to an in estimate the antibiotic susceptibility of P. gingivalis and P. interrnedia isolate from the subgingival plaque to adult periodontitis. Six P. gingivalis and five P. intermedia bacterial strains were tested for their susceptibility to 10 antimicrobial agents under disc diffusion method and broth dilution method. Ten patients with deep pocket(6mm) were selected for this study. They had not taken antibiotics for 6 months and no history of dental treatment for 6 months before this study. The result were as follow : 1. For antibiotic disc diffusion method, six P. gingivalis and five P. interrnedia were tested with 10 antimicrobial agents which comprised penicillin, gentamycin, clindamycin, lincomycin, ampicillin, erythromycin, tetracycline, amikacin, chloramphenicol, vancomycin. The sensitive antibiotics were tetracycline, penicillin, ampicillin, vancomycin, chloramphenicol and resisitent antibiotics were lincomycin. The other antimicrobial agents were less active. 2. From the study of determination on the minimal inhibitory concentration(MIC) by broth dilution method, the MIC of tetracycline to P. gingivalis and P. intermedia were $0.5-1.0{\mu}g/ml$, $0.5{\mu}g/ml$, that of ampicillin were $1-8{\mu}g/ml$, that of clindamycin were $1-32{\mu]g/ml$, $8-16{\mu}g/ml$, that of lincomycin were $16-32{\mu}g/ml$, $2-32{\mu}g/ml$. These data suggest that tetracycline and ampicillin may be valuable drug in the elemination of P. gingivalis and P. interrnedia from the patients with adult periodontitis.

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Minimally Invasive Muscle Sparing Transmuscular Microdiscectomy : Technique and Comparison with Conventional Subperiosteal Microdiscectomy during the Early Postoperative Period

  • Park, Beom-Seok;Kwon, Young-Joon;Won, Yu-Sam;Shin, Hyun-Chul
    • Journal of Korean Neurosurgical Society
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    • v.48 no.3
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    • pp.225-229
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    • 2010
  • Objective : The authors introduce a minimally invasive muscle sparing transmuscular microdiscectomy (MSTM) to treat herniated lumbar disc disease. Its results are compared with conventional subperiosteal microdiscectomy (CSM) to validate the effectiveness. Methods : Muscle sparing transmuscular microdiscectomy, which involves muscle dissection approach using the natural fat cleavage plane between the multifidus to expose the interlaminar space, was performed in 23 patients to treat a single level unilateral lumbar radiculopathy. The creatine phosphokinase (CPK)-MM serum levels were measured on admission and at 1, 3, and 5 days postoperatively. Postoperative pain was evaluated using a 10-point visual analogue scale (VAS) and recorded on admission and at 1, 3, and 5 days postoperatively. The results were compared to those from the conventional subperiosteal microdiscectomy (43 patients). Results : The CPK-MM levels were significantly lower in the serum of the MSTM group compared to the CSM group on postoperative days three and five (p = 0.03 and p = 0.02, respectively). The clinical scales for back pain using VAS were significantly lower in the MSTM group than in the CSM group on postoperative days three (p = 0.04). The mean VAS scores for leg pain in both groups showed no significant differences during the early postoperative period. Conclusion : Muscle sparing transmuscular microdiscectomy is a minimally invasive surgical option to treat lumbar radiculopathy due to herniated disc. The approach affected minimal injury to posterior lumbar supporting structures with alleviated postoperative back pain.

A Study on the Influence of Lumbar Lordosis and Intervertebral Disc Angle by Obesity (비만에 의한 허리뼈 전만과 추간판 각도의 영향에 관한 연구)

  • Kwak, Jong Hyeok;Choi, Min Gyeong;Kim, Neung Gyun;Kim, A Yeon;Kim, Gyeong Rip
    • Journal of the Korean Society of Radiology
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    • v.14 no.3
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    • pp.235-243
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    • 2020
  • Lumbar Lordosis Angle (LLA) is an index that can be used to evaluate the curvature of the lumbar vertebrae. It can measure the structural stability of the lumbar spine and the stability of each segment of the vertebral column at the intervertebral disc angle (IDA). Especially, our data shows it is found to be a strong positive correlation between obesity and the angle of lordosis for lumbar vertebrae. Also, the reason for the large IDA in the case of obesity seems to be the result of the weakening of anatomical structure as well as the gravity effect. And, the obesity interferes with normal sagittal balance and fails to maintain a straight posture with minimal energy. Therefore, the obesity can be an important factor in causing back pain by changing the lumbar lordosis.

Screening of anti-candidiosis agent from medicinal and wild plants (Candidiosis 치료제 개발을 위한 약용 및 야생 식물의 항진균 활성의 검색)

  • 손호용;금은주;권윤숙;권기석;진익렬;권하영;권정숙;손건호
    • Journal of Life Science
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    • v.13 no.5
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    • pp.604-617
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    • 2003
  • Candida albicans is one of the most common etiological agents in fungi-associated skin infections. There is an increase of candidiosis especially in the patient of acquired or induced immunodeficiency syndromes or in the event of long-term antibiotics and immuno-suppressor or cytotoxic therapies. To screen out reliable and effective anti-candidiosis agent, in this study, we have evaluated antifungal activity of 298 plant extracts against C. albicans. Based on the results of disc-paper method and determination of minimal inhibitory concentration, fifteen extracts were finally selected as possible sources of anti-candidiosis agent. Especially, six different plant extracts, such as Rubus parvifolius, Euphorbia pekinensis, Coptis chinensis, Eugenia aromaticum, Paeonia lactiflora var. hortensis and Paeonia suffruticosa showed strong antifungal activity against C. albicans, not to S. cerevisiae. These results suggested that medicinal and wild plants could be the potential source of antifungal agent.