• Title/Summary/Keyword: miR-29a

Search Result 220, Processing Time 0.035 seconds

Factors Influencing Health-Promoting Behaviors in People Living with HIV (HIV 감염인의 건강증진행위에 영향을 미치는 요인)

  • Park, Young Mi;Shin, Gisoo;Kim, Jiyoung
    • Korean Journal of Adult Nursing
    • /
    • v.26 no.2
    • /
    • pp.234-243
    • /
    • 2014
  • Purpose: The purpose of this study was to investigate the factors influencing the health-promoting behaviors of the people living with HIV. Methods: Descriptive cross-sectional study design was used. The study participants included 99 people living with HIV recruited via the Korea HIV/AIDS Network of Solidarity from May 15 to August 15, 2012. Self-report questionnaires were used fo data collection measuring perceived stress, depression, self-efficacy, health-promoting behaviors (HPLP-II), and the perceived health status. The analysis was done using SPSS/Win 18.0 program. Descriptive statistics, pearson correlation, t-test, ANOVA and stepwise multiple regressions were used for data analysis. Results: Perceived stress (r=-.21, p=.040), depression (r=-.37, p<.001), self-efficacy (r=.42, p<.001), perceived health status (r=.29, p=.003), and health-promoting behaviors were significantly correlated with each other. The self-efficacy, religion and perceived health status were significant factors, which explained about 26% of the variance of the health-promoting behaviors. Multiple regression analysis showed that a powerful predictor of health-promoting behaviors among people living with HIV was self-efficacy. Conclusion: This study suggested that a focus of nursing intervention program on self-efficacy is necessary in order to increase health-promoting behaviors among people living with HIV.

A Study of the Characteristics of the HRV of the Girl Showing a Precocious Puberty (성조숙 증상을 보이는 여아들의 HRV의 특성 연구)

  • Yang, Seung-Jeong;Park, Kyung-Mi;Cho, Seong-Hee
    • The Journal of Korean Obstetrics and Gynecology
    • /
    • v.29 no.3
    • /
    • pp.10-22
    • /
    • 2016
  • Objectives: The aim of the study was to investigate the characteristics of the autonomic innervation of the heart in Precocious Puberty (PP) Girls.Methods: We studied 87 girls visiting Dongshin University Suncheon Oriental Medicine hospital from first Januarty 2013 to 31th December 2015. Among the 87 girls who were selected 14 people under the age of 8. The subjects were categorized in two groups, 2 PP girls and 12 healthy controls. We studied the difference of Heart rate variability (HRV) between two groups by Independent samples T-test using SPSS for windows (version 22.0).Results: The Standard deviation of all normal R-R intervals (SDNN), The spuare root of the sum of the spuare of difference between adjacent normal R-R intervals (RMS-SD) of PP group was non-significantly lower than non-PP group. Total power (TP), Very low frequency power (VLF), High frequency power (HF), Low frequency power (LF) of PP group was non-significantly lower than non-PP group, LF/HF ratio of PP group was significantly higher than non-PP group. Normalized high frequency power (HF norm) of PP group was non-significantly lower than non-PP group. Normalized low frequency power (LF norm) of PP was non-signficantly higher than non-PP group.Conclusion: The results suggest that imbalance of sympathetic and parasympathetic nervous system from girls of precocious puberty can be seen.

The Efficacy of Recombinant Human Follicle Stimulating Hormone (rhFSH) in Human IVF-ET Program (체외수정시술시 유전자 재조합 난포자극호르몬제의 효용성)

  • Han, Kuk-Sun;Lee, Hong-Bok;Song, In-Ok;Park, Yong-Seog;Byun, Hye-Kyung;Jun, Jin-Hyun;Koong, Mi-Kyoung
    • Clinical and Experimental Reproductive Medicine
    • /
    • v.29 no.1
    • /
    • pp.45-56
    • /
    • 2002
  • Objectives: Recently, recombinant FSH (rFSH) has been manufactured using a Chinese hamster ovary cell line transfected with the gene encoding human FSH. Both rFSH and urinary gonadotropin (uFSH) could be used for controlled ovarian hyperstimulation (COH). However, uFSH implies a number of disadvantages, such as batch-to-batch inconsistency, no absolute source control, dependence on large amounts of urine, low specific activity, and low purity. The purpose of this study was to evaluate the efficacy of rFSH in human IVF-ET program. Materials and Methods: A total of 508 infertile women was enrolled in this study. They are classified into rFSH group (n=177) or uFSH group (n=331), and all of them were matched by age and cause of infertility in same period. The $Puregon^{(R)}$ (Organon, Holland) was used as rFSH, and the Metrodin-$HP^{(R)}$ (Serono, Switzeland) and $Humegon^{(R)}$ (Organon, Holland) was used as uFSH. We subdivided the patients into three age groups. The outcomes of IVF-ET program were analyzed using the statistical package for social sciences (SPSS). Results: There was no significant differences in the level of estradiol on hCG injection day, the numbers of retrieved oocytes, matured oocytes, fertilized oocytes, transferred embryos, frozen embryos between the two groups. The total dose (IU) of gonadotropin for COH was significantly lower in the rFSH group compared to uFSH group ($1339{\pm}5491.1$ vs $2527.8{\pm}1075.2$ IU, p<0.001). Clinical pregnancy rate per embryo transfer in the rFSH group showed increasing tendency, compared to the uFSH group, but there was no statistical significance (35.2% vs 29.3%). Our results demonstrated that the relative efficiency of rFSH compared with uFSH is higher in older patients. Conclusions: The ovarian stimulatory effect and clinical outcome of recombinant FSH was similar to that of the urinary gonadotropin. The IVF-ET cycles with significantly lower dose of gonadotropin in rFSH group showed comparable results. Therefore, we suggest that recombinant FSH is more potent and effective than urinary gonadotropin.

Anti-inflammatory and Anti-oxidative Activities for Extract of Fermented Ligustrum japonicum Fruits (광나무 열매 발효 추출물의 항염 및 항산화 활성)

  • Jung Eun Kim;So Hee Kim;Mi Ae Kim;Mi Sun Ko;Chan Seong Shin;Nam Ho Lee
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.49 no.2
    • /
    • pp.117-125
    • /
    • 2023
  • In this study, the anti-inflammatory and anti-oxidative activities were compared for the extracts of non-fermented Ligustrum japonicum fruits (LJF) and fermented counterparts. U se of Latilactobacillus curvatus (L. curvatus) and Weissella minor (W. minor), isolated from the Jeju Chromis notata, as fermented strains led to the extracts of LJF-LC and LJF-WM in this experiment. The yield of each fermented extract (LJF-LC and LJF-WM) was 40.5 ~ 46.0%, higher than 29.5% of non-fermented extract (LJF). As a result of an activity experiment using RAW 264.7 macrophages stimulated by lipopolysaccaride (LPS), it was confirmed that LJF-WM, a fermented extract, has an excellent effect of inhibiting NO production in a concentration-dependent manner without cytotoxicity. Upon the screening of DPPH and ABTS+ radical scavenging activities, the fermented LJF-LC and LJF-WM showed comparable to the non-fermented LJF. In the study of cell protection effect using HaCaT keratinocytes damaged by hydrogen peroxide (H2O2), the fermented LJF-WM indicated protective effect against oxidative stress. In addition, quantitative analysis of a major constituent salidroside by HPLC indicated about 15.6 mg/g for the LJF-LC and 13.9 mg/g for the LJF-WM, which were higher than that of non-fermented LJF (12.0 mg/g). Based on these results, it was suggested that the fermented extract from L. japonicum fruits could be used as a natural cosmetics material with anti-inflammatory and anti-oxidative effects.

A Correlation Study on Nursing Professional Values, Department Satisfaction, Sociality, Self-Esteem among Nursing Students (간호학생의 간호전문직관과 전공만족, 사회성, 자아존중감간의 관계)

  • Yeun, Eun-Ja;Kwon, Young-Mi
    • Journal of Korean Academy of Nursing Administration
    • /
    • v.13 no.3
    • /
    • pp.285-292
    • /
    • 2007
  • Purpose: The purpose of this study was to identify the factors influencing the nursing professional values(NPV) of college nursing students. Methods: A convenience sample of 274 subjects was recruited from the department of nursing at a college. The survey was conducted from May 29 to Jun 20 2006. The data was analyzed using descriptive statistics, Pearson correlation coefficients, and stepwise multiple regression with SPSS/WIN 10.1. Results: The average item score of NPV, satisfaction, socialization, self-esteem were 3.60, 3.00, 2.74, and 2.71. The NPV of nursing students showed a significantly positive correlation to speciality satisfaction(r=.28-.46), socialization(r=.13-.46), and self-esteem(r=.12-.15). The significant factors influencing NPV of nursing students were service, curriculum satisfaction, social perception satisfaction, leadership & popularity, and sociability, which explained about 37.5%. Conclusions: Therefore, on the basis of this study's result, when nursing educational programs are developed to make positive NPV, these factors need to be considered.

  • PDF

Factors Affecting Posttraumatic Stress in New Firefighters (신임 소방대원의 외상 후 스트레스 영향요인)

  • Baek, Mi Lye
    • Journal of the Korean Society of Safety
    • /
    • v.29 no.5
    • /
    • pp.123-128
    • /
    • 2014
  • This study investigated a posttraumatic stress, social support, and work burden and identified related factors which exerted influence on posttraumatic stress of new firefighters. Data were gathered from total of 144 new firefighters. Also, 22 PTS items, 20 work burden items, and 8 social support items were analyzed by SPSSWIN 21.0 program. Posttraumatic stress according to general characteristics showed significant difference in gender(t=-2.57, p=0.01), experience of self danger(t=3.06, p=0.00), experience of rescuee danger(t=2.41, p=0.02), and experience of colleague danger(t=3.43, p=0.00). High risk group of PTS was 20.1%. Posttraumatic stress, social support, and work burden showed significant difference in the high and low risk group. Posttraumatic stress was correlated with work burden(r=0.34, p=0.00), social support(r=-0.29,p=0.00). Factors influencing PTS were Experience of colleague danger(${\beta}$=1.274, 95% CI=0.08-0.96), social support(${\beta}$=-0.090, 95% CI=0.85-0.98) and work burden(${\beta}$=0.057, 95% CI=1.02-1.10). We need to reduce the work burden caused by influencing variable of traumatic stress and create more preventive discipline of traumatic stress for the new firefighters to improve the social support at work or home. Also, posttraumatic stress has to be managed consistently with support by changing the social attitudes and we need to seek the new system that anybody can get a consultation of a specialist.

A STUDY ON THE SIZE AND VOLUME OF THE PALATE (구개의 크기 및 용적에 관한 연구)

  • Baik, Byeong-Ju;Kim, Mi-Ra;Kim, Jae-Gon;Yang, Yun-Mi
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.29 no.3
    • /
    • pp.397-406
    • /
    • 2002
  • The purpose of this study was to clarify the palatal arch length, width and volume in the primary and permanent dentition. Samples were consisted of normal occlusion in the primary dentition(50 males and 50 females) and permanent dentition(43 males and 43 females). Their upper plaster casts were used and through 3-dimensional laser scanning(3D Scanner, DS4060, LDI, U.S.A.), cloud data, polygonization, section curve, loft surface and fit and horizontal plane were made for measuring the palatal arch length, width and volume(Surfacer 10.0, Imageware, U.S.A.). Correlation coefficients were calculated separately for males and females in each group(SPSS 10.0). The results were as follows : 1. Average distance from the fit plane to the points(tooth-tooth-palate) was greater in the permanent dentition than those of primary dentition. 2. Palatal volume was greater more than 3 times in the permanent dentition, especially it was greater in male compared to female with significance(p<0.05). 3. Palatal width of male was greater in the primary and permanent dentition but palatal length, only in the permanent dentition than that of female(P<0.05). 4. Correlation coefficients were statistically most significant between the palatal volume and size of posterior palatal width and total palatal length(r=0.401, r=0.450, r=0.678, r=0.654).

  • PDF

Verification of Utility of Simple Mensuration of Cl- from Urine to Estimate the Amount of Sodium Intake (나트륨 섭취량 추정을 위한 소변 중 Cl-의 간이적 측정방법의 유용성 검증)

  • Lee, Sung-Ho;Lee, Chae-Joon;Ju, Sung-Mi;Lee, Hyun-Joo;Ra, Wang-Yeon;Kim, Soon-Ok
    • The Korean Journal of Food And Nutrition
    • /
    • v.29 no.1
    • /
    • pp.27-32
    • /
    • 2016
  • The purpose of this study was to measure concentrations of $K^+$, $Na^+$, $Cl^-$ by ionometer with check salt strip, simple salimeter and Ion-selective electrode (ISE) and compare the results of each mensuration; furthermore, the possibility of inferring the $Na^+$ concentration from $Cl^-$ concentration of urine and the impact of $K^+$ on the concentration of each ion was examined. The results showed that ISE determined $Na^+$ and $Cl^-$ concentrations in the urine are highly interrelated (R=0.9039); in addition, concentrations of $Cl^-$, measured with strip and ISE from urine are highly interrelated (R=0.9338). The concentration of $Na^+$ in urine, inferred by measuring $Cl^-$ concentration with strip, has a high relationship (R=0.8580) with the concentration of $Na^+$ in urine, measured by ISE. The results of our study will increase awareness of $Na^+$ intake and the utility of check salt strip, as well as the possibility of inferred $Na^+$ concentration from measures of $Cl^-$ concentration as a screening test for reducing sodium intake.

Impact of COVID-19-Related Stress and Depression in Public Sector Workers (코로나 19 관련 공공근로자에서의 우울증상 및 스트레스 반응)

  • Park, Jinsol;Cho, Hye-mi;Ko, Min-soo;Chi, Su-hyuk;Han, Changsu;Yi, Hyun-suk;Lee, Moon-Soo
    • Korean Journal of Psychosomatic Medicine
    • /
    • v.29 no.2
    • /
    • pp.136-143
    • /
    • 2021
  • Objectives : The coronavirus disease 2019 (COVID-19) outbreak is a global medical crisis imposing particular burden on public sector employees. The aim of this study was to investigate the psychiatric distress among public sector workers amid the COVID-19 pandemic. Methods : We conducted a cross-sectional study with 531 public sector workers in Gwangmyung city who completed Korean versions of the Perceived Stress Scale (PSS), Patient Health Questionnaire-9 (PHQ-9), and Impact of Event Scale-Revised-Korean (IES-R-K). Results : The results revealed more than moderate levels of stress (85.2%), depressive symptoms (22.2%), and posttraumatic stress symptoms (38.8%). PSS total score was significantly correlated with PHQ-9, IES-R-K total scores as well as IES-R-K subscale scores. Total scores on the PSS, PHQ-9, and IES-R-K were all inversely correlated with age. Conclusions : COVID-19-related workers experience considerable stress and depressive symptoms, with self-rated stress correlating significantly with depression scores. Age may serve as a protective factor against occupational stress and burnout. These findings highlight the need for adequate psychiatric screening and intervention for public sector workers.

A Study of The Effect of Waiting time for Operation in the Operating Room on Preoperative Patients (수술환자에 있어 수술실내에서 수술대기 시간이 불안에 미치는 영향에 관한 연구)

  • Lee, Hea-Won;Lee, Kyu-Chung;Kim, Hae-Ock;Lee, Haik-Ock;Kim, Hea-Suk;Lee, Mi-Kyung;Song, Mal-Soon
    • The Korean Nurse
    • /
    • v.29 no.3
    • /
    • pp.36-48
    • /
    • 1990
  • This study was attempted to provide us with basic information on how to improve understanding with patients for operation, and to offer then better nursing and treatment. This kind of study will help scientific application to nursing practice and operating room. The data was collected by interviewing 29 patients who underwent the elective surgery under the general anesthesia at Y hospital in Seoul. The interview ran from October 15 to December 15, 1989. The research instrument was a anxiety measurement device (SAAI) originally developed by Spielberger, et al and modified by Jung-Tack Kim. 1. Hypothesis Testing Hypothesis one was that there would be a difference in state anxiety level according to a time difference in watiting for operation. This hypothesis was rejected(state.anxiety level one hour before operation P>.05, r-.747, State anxiety level half an hour before operation P>.05, r-.1550, state anxiety level just before operation, P>.05, r=.1099). However, state anxiety, evel appeared to be associated with a longer watiting period, like one day before operation (P<.05, r-.4628). Hypothesis two was that there would be a difference according to state anxiety level of patients for operation. This was rejected. (Change of blood perssure in systolie P>.05 r=.1082, Change of blood pressure in diastolic P>.05, r=.088, Change of pulse rate, P>.05, r-1.909) 2. Examining trait anxiety and state anxiety levels, the average level of trait anxiety was 42.034, and the average level of state anxiety one day before operation was 43,000. The average level of state anxiety was averaged 42.356 in a waiting room for operation. 3. Examining the state anxiety level by time period, the one hour before was 42.379 the level half an hour before 42.276, and the level just before operation 42.414. The low level of state anxiety was due to the fact that premedication was not eliminated. 4. Age and time period like one day before operation was related to state anxiety level (F=5.271, P<.0.01) and blood pressure in waiting room for operation. That is, state anxiety level and blood pressure of patients one day before operation appeared high. Sex was relation to changes of blood pressure ; the blood pressure of male patients appeard higer than of female patients. A marital status was also related anxiety level one hour before operation the married patient for operation showed a higher state anxiety level than that of the unmarried patient for operation. Education was similarily related to trait anxiety level in which highly educated patients show lower levels of trait anxiety than poorly educated ones. Motive for hospitalization was related to state anxiety level for patient one hour before operation (F=6.464, P<.05) likewise, patients who are supposed to undergo operation hastily showed higher levels of anxiety than patients who expect elective surgeries.

  • PDF