• Title/Summary/Keyword: miR-20a

Search Result 542, Processing Time 0.028 seconds

A Study of Test-Retest Reliability and Interrater Reliability of the Sensory Processing Scale for Children (SPS-C) (아동감각처리척도(Sensory Processing Scale for Children; SPS-C)의 검사-재검사 신뢰도와 검사자간 신뢰도 연구)

  • Kim, Kyeong-Mi;Kim, Ga-Yeon;Lee, Seung-Jin
    • The Journal of Korean Academy of Sensory Integration
    • /
    • v.20 no.2
    • /
    • pp.11-21
    • /
    • 2022
  • Objective : This study examined the test-retest reliability and interrater reliability of the Sensory Processing Scale for Children (SPS-C). Method : Senventy primary caregivers of children with sensory processing difficulties and 3 years old participated in the study. The subjects were recruited through child development centers, welfare centers, and acquaintances located in Seoul, Gyeonggi-do, Busan, and Gyeongsang-do. The test-retest reliability verification targeted 20 main caregivers of children with difficulty in sensory processing. Re-evaluation was performed within 7 to 14 days after the initial evaluation, and Pearson's correlation coefficient was used to confirm the relevance between the two time points, and the Intraclass correlation coefficient was used to confirm the degree of agreement. The interrater reliability verification was conducted with 18 primary caregivers and 18 subsidiary caregivers of children with sensory processing difficulties. Each caregiver evaluated the same child, and the Intraclass correlation coefficient was used to confirm the agreement between the two sets of caregivers. Results : The test-retest reliability was Pearson's correlation coefficient r=.914 and intraclass correlation coefficient ICC=.939, indicating a high level of relevance and agreement. The interrater reliability was an Intraclass correlation coefficient ICC=.727, which showed a moderate level of agreement, but the tactile area (ICC=.455) and proprioceptive area (ICC=.439) were not statistically significant and showed a low degree of agreement. Conclusion : Through this study, it was confirmed that the children's Sensory Processing Scale for Children (SPS-C) is a stable evaluation tool with test-retest reliability and interrater reliability verified, and it will be able to provide help in standardization studies for future clinical use.

A Study on Occupational Care Diver Though Nurse's Experiences in General Hospitals (일부 종합병원 간호사들이 경험한 간병인에 대한 연구)

  • Kim, Hae-Soon;Kim, Sook-Young;Park, Mi-Sung
    • Research in Community and Public Health Nursing
    • /
    • v.5 no.2
    • /
    • pp.216-226
    • /
    • 1994
  • This study attempted to analize nurse's experiences about care giver including nurse's recognition of occupational care giver's existence, the helping part of occupational care giver's activities, problems between occupational care giver and nurse, and correlations between reasons of problems and each variable. The subjects of the study are 218 nurses who are working at general hospitals. The study informations gathered by using structured questionnaire which consisted of 38 items. The reliability of the instrument was cronhach's 0.8310. The collected data was analized by spss program for the statistics of percent, t-test, ANOVA, and Pearson's correlation. The study results were as follows : 1. For the nurse's recognition of occupational care giver's existence 70.2% of nurses(153 nurses) who felt occupaitional care giver's existence was helpful. The result showed 2.20 when transfered to score. 2. Occupational care giver's activities which were helpful to nurses were in order of following : simple serving, personal hygiene, companion of talking, room arrangement, and saftey management. 3. Among 10 items of the problems which nurses having experiences with occupational care givers, 4 items were related with nurses directly. 88.4% of the reasons of the problems were due to lack of occupational care giver's eduction. 4. For the relationships of general characteristics and nurse's reason of problems there was the significant difference in the nurse's status and education. There was the significant difference showed in the group of over status of charge nurse and over college education(T=-2.08, P<0.05, T=-2.13, P<0.01) 5. Correlation between nurse's recognition of occupational care giver's existence and the problems between care giver and the nurse revealed weak relationship (r=0.2002, P<0.01). However, correlation between nurse's recognition of occupational care giver's existence and degree of occupational care giver's helping and also relationship of degree of care giver's helping and problems between these two groups were not statistically significant.

  • PDF

Bacillus licheniformis Isolated from Korean Traditional Food Sources Enhances the Resistance of Caenorhabditis elegans to Infection by Staphylococcus aureus

  • Yun, Hyun Sun;Heo, Ju Hee;Son, Seok Jun;Park, Mi Ri;Oh, Sangnam;Song, Min-Ho;Kim, Jong Nam;Go, Gwang-Woong;Cho, Ho-Seong;Choi, Nag-Jin;Jo, Seung-Wha;Jeong, Do-Youn;Kim, Younghoon
    • Journal of Microbiology and Biotechnology
    • /
    • v.24 no.8
    • /
    • pp.1105-1108
    • /
    • 2014
  • We investigated whether Bacillus spp., newly isolated from Korean traditional food resources, influence the resistance of hosts to foodborne pathogens, by using Caenorhabditis elegans as a surrogate host model. Initially, we selected 20 Bacillus spp. that possess antimicrobial activity against various foodborne pathogens, including Staphylococcus aureus. Among the selected strains, six strains of Bacillus spp. used in preconditioning significantly prolonged the survival of nematodes exposed to S. aureus. Based on 16S rRNA gene sequencing, all six strains were identified as B. licheniformis. Our findings suggest that preconditioning with B. licheniformis may modulate the host defense response against S. aureus.

Factors Related to the Stage of Mammography Screening in Married Korean Women (기혼 여성의 유방조영술 검진 행위에 대한 영향요인)

  • Hur, Hea-Kung;Park, So-Mi;Kim, Gi-Yon
    • Korean Journal of Adult Nursing
    • /
    • v.16 no.1
    • /
    • pp.72-81
    • /
    • 2004
  • Purpose: The purpose of this study was to examine factors related to different stages of mammography screening based on the transtheoretical model (TTM) and health belief model (HBM). Method: 143 women were recruited from community centers in W city. The mean age was 44.08 (SD=7.78) and 74 (51.7%) had experienced education on preventative behavior related to breast cancer. The Decisional Balance Scale (Pros and Cons of mammography) and Stages of Adoption of Mammography Scale by Rakowski et al. (1992) and the revised Health Belief Model Scale (Perceived Seriousness, Perceived Susceptibility and Health Motivation) by Champion (1993) were used. Result: According to the stage of adoption of mammography, 17.4% of the women were In pre-contemplation, 45.5% in contemplation, 24.5% in action, and 12.6% in maintenance. The mean differences for pros, and the decisional balances between the stages of mammography adoption were significant (F=8.84, p=.000; F=7.20, p=.000). Education related to prevention of breast cancer was the most important variable. Prevention education, history of breast disease and pros of mammography explained the stages of mammography adoption ($R^{2}=26%$). Conclusion: Findings support TTM as a useful tool for improving mammography adherence. Behavioral interventions that target decisional balance and health belief can effectively promote adherence to mammography.

  • PDF

A Study on Risk Factors of Musculoskeletal Disorders among Selected Female Hair Dressers (일부 여성 미용종사자들의 근골격계 증상의 위험요인)

  • Song, Mi-Ra;Han, Sung-Hyun
    • Journal of Korean Society of Occupational and Environmental Hygiene
    • /
    • v.15 no.3
    • /
    • pp.250-260
    • /
    • 2005
  • This study was designed to find the symptom prevalence rates of musculoskeletal disorders and the risk factors of musculoskeletal disorders among selected hair dressers. Methods; The survey were conducted from July 1 to 30, 2004 for 459 hair dressers working in Seoul and Gwangju using self-administration questionnaire. The risk factors on musculoskeletal disorders have analysed by multiple linear regression analysis. The results of this study are summarized as follows: The experience rate of musculoskeletal disorders symptom in the last one year was 56.4%. The experience rates of each body parts were 36.4% on the shoulders, 30.5% on the legs and the feet, 28.5% on the low back, 27.0% on the hand and the fingers, 23.3% on the neck and 17.0% on the arms and the elbows. The prevalence rate of musculoskeletal disorders symptom in the last one week was 40.5%, those of each body parts were 24.0% on the legs and the feet, 21.4% on the shoulders, 20.7% on the low back, 15.7% on the hand and the wrists, 15.0% on the neck, 9.4% on the arms. The risk factors on musculoskeletal disorders were working posture(${\beta}=0.32$), perceived stress(${\beta}=0.19$), working period(${\beta}=0.16$), standing working over 10 hour(${\beta}=0.16$), hard working(${\beta}=0.11$). The adjusted determinant coefficient($R^2$) of this regression model was 0.267. Based on the results, in order to prevent musculoskeletal disorders of hair dressers, working posture shall be improved and leisure opportunities to relieve stress, and health management program shall be provided.

Analysis on the Donators' Characteristics of Government-dominant and Non-governmental Food Bank Programs (정부주도형 및 민간주도형 푸드뱅크(Food Bank) 사업의 기탁 특성 분석)

  • Jo, Mi-Na;Hong, Min-Ah;Kang, Hye-Seung;Yang, Il-Sun
    • Korean Journal of Community Nutrition
    • /
    • v.11 no.5
    • /
    • pp.618-628
    • /
    • 2006
  • The purpose of this study was to examine the donators' characteristics and donative foods of both government-dominant and non-governmental food bank program, to understand the problems and benefits of food bank program, and to find the solutions to activate food bank program. The questionnaires were distributed to 120 food bank operators and 3 donators were selected from each food bank for the survey from April 2002 to May 2002. 118 sheets (32.8%) from government-dominant food bank and 53 sheets (20.1%) from non-governmental food bank were collected. The main results of this study were as follows: The largest donators to either government-dominant or non-governmental food bank programs were bakery and confectionery companies 31.4% and 45.3% respectively. The majority of donated foods were 'goods in stock' (55.6%) and frequency of donation were largely on a daily basis (27.1% for government-dominant and 22.6% for non-governmental). Some of the donators who had more donative food did not donate, and the reasons were closeness to expiration date of food (67.3%), lack of legal protection in the event of food poisoning (54.5%), and poor public image of food related accidents (52.3%).

Comparative Study of White and Steamed Black Panax ginseng, P. quinquefolium, and P. notoginseng on Cholinesterase Inhibitory and Antioxidative Activity

  • Lee, Mi-Ra;Yun, Beom-Sik;Sung, Chang-Keun
    • Journal of Ginseng Research
    • /
    • v.36 no.1
    • /
    • pp.93-101
    • /
    • 2012
  • This study evaluated the anti-cholinesterases (ChEs) and antioxidant activities of white ginseng (WG) and black ginseng (BG) roots of Panax ginseng (PG), P. quinquefolium (PQ), and P. notoginseng (PN). Ginsenosides $Rg_1$, Re, Rf, $Rb_1$, Rc, $Rb_2$, and Rd were found in white PG, whereas Rf was not found in white PQ and Rf, Rc, and $Rb_2$ were not detected in white PN. The major ginsenoside content in steamed BG including $RK_3$, $Rh_4$, and 20(S)/(R)-$Rg_3$ was equivalent to approximately 70% of the total ginsenoside content. The WG and BG inhibited acetylcholinesteras (AChE) and butyrylcholinesterase (BChE) in a dose dependent manner. The efficacy of BG roots of PG, PQ, and PN on AChE and BChE inhibition was greater than that of the respective WG roots. The total phenolic contents and 2, 2-diphenyl-1-picryl-hydrazyl (DPPH) scavenging activity were increased by heat treatment. Among the three WG and BG, white PG and steamed black PQ have significantly higher contents of phenolic compounds. The best results for the DPPH scavenging activity were obtained with the WG and BG from PG. These results demonstrate that the steamed BG roots of the three studied ginseng species have both high ChEs inhibition capacity and antioxidant activity.

A Study on the Radioprotective Effects of Foods -Focusing on the Glycobiological Properties of Mushrooms- (식품류를 이용한 방사선 방호 효과 -버섯류의 당 생물학적인 특징중심으로-)

  • Kim, Jong-Soo;Ahn, Byeong-Kwon;Choi, Hyun-Suk;Choi, Du-Bok;Yeom, Jung-Min;Kim, Soong-Pyung;Lee, In-Sung;Cho, Mi-Ja;Cha, Wol-Suk
    • KSBB Journal
    • /
    • v.30 no.1
    • /
    • pp.11-20
    • /
    • 2015
  • Radiation causes various pathophysiological alterations in living animals, and it causes death at high doses by multiple mechanisms, including direct DNA damage and indirect oxidative stress. The search for useful radioprotectors has been an important issue in the field of radiation biology. Ideal radioprotectors should have low toxicity and an extended window of protection. As many synthetic compounds have toxic side effects, the natural products have attracted scientific attention as radioprotectors. Natural products that have been recently shown to be effective with various biological activities were found to have radioprotective effect. The aim of this review is to summary the recent research of the radioprotective effects of natural foods, especially focused on the glycobiological properties of mushrooms.

The Impact of Psychological Insulin Resistance on Self-Care Activities in Patients with Type 2 Diabetes Mellitus Undergoing Insulin Therapy (인슐린요법을 받는 제2형 당뇨병 환자의 심리적 인슐린저항성이 자가관리에 미치는 효과)

  • Kim, Mi Gyeong;Song, Hyo Jeong
    • Journal of Korean Biological Nursing Science
    • /
    • v.24 no.1
    • /
    • pp.58-66
    • /
    • 2022
  • Purpose: The purpose of this study was to identify the level of psychological insulin resistance and self-care activities and to evaluate the factors affecting self-care activities in patients with type 2 diabetes mellitus undergoing insulin therapy to provide basic data for the development of educational programs. Methods: Data were collected through the interviews using a structured questionnaire from August 29 to October 20, 2017, from the patients with type 2 diabetes mellitus visiting the Diabetes Mellitus Center at H-General Hospital in J-city. The subjects were 168 patients who had been being treated via self-injection for at least three months after the start of insulin therapy. Data analyses were conducted using t-test, ANOVA, Pearson's correlation coefficients, and stepwise multiple regression using the SAS WIN 9.2 program. Results: The mean score of psychological insulin resistance was 61.25 (range 19-95) and the mean score of self-care activities was 53.19 (range 18-90). Self-care activities were significantly different by gender (t = -2.94, p= .004), perceived health status (F= 7.00, p< .001), and hypoglycemia during the last three months (t= -2.47, p= .015). Negative correlation was observed between psychological insulin resistance and self-care activities (r= -.33, p< .001). Self-care activities were significantly predicted by psychological insulin resistance, perceived health status, gender, and hypoglycemia during the last three months, and 19.0% of the variance in self-care activities was explained (F= 9.01, p< .001). Conclusion: Psychological insulin resistance in patients undergoing insulin therapy and its effects on self-care activities identified in this study will be useful in starting and maintaining insulin therapy in the future.

Determination of Benzimidazole Residues in Livestock Products (축산식품 중 벤지미다졸계 구충제 잔류실태 조사)

  • Lee, Kyung-Jin;Kang, Young-Woon;Kang, Eung-Ui;Kim, Mi-Ran;Bahn, Kyeong-Nyeo;Jang, Young-Mi;Kim, Mee-Hye
    • Korean Journal of Food Science and Technology
    • /
    • v.42 no.5
    • /
    • pp.515-520
    • /
    • 2010
  • This research investigated benzimidazole residues (albendazole, fenbendazole, flubendazole, thiabendazole, oxibendazole) in livestock products. A total of 270 samples of livestock products (beef, pork and chicken) were purchased from local markets in Korea. Ethyl acetate was used to extract analytes from the sample, after which ethyl acetate extracts were purified using a MCX cartridge. Analytes were detected using liquid chromatography-tandem mass spectrometry. The limit of detection was 0.01-0.04 ppb, the limit of quantification was 0.03-0.13 ppb, the linearity ($r^2$) was 0.9992-1.0000, and the recovery was 70-85%. Residues of benzimidazoles, except for fenbendazole in pork, were not found in any of the 270 livestock samples. Fenbendazole was detected in the range of 1.2 to 3.1 ppb in 12 samples of pork.