• Title/Summary/Keyword: miR-19a

Search Result 311, Processing Time 0.026 seconds

Factors Influencing Self-Identity and Menopausal Symptoms on Level of Depression in Middle Aged Women (중년여성의 자아정체감, 갱년기 증상이 우울에 미치는 영향)

  • Han, Mi-Jeong;Lee, Ji-Hyun
    • Women's Health Nursing
    • /
    • v.19 no.4
    • /
    • pp.275-284
    • /
    • 2013
  • Purpose: The purpose of this study was to identify the factors influencing self-identity and menopausal symptoms their influence on level of depression in middle-aged woman. Methods: Participants were 135 middle-aged women who were living in city B, were 45-60 years old, informed of study purpose, and agreed to participate. Data were collected from December, 2012 to January, 2013 using scales measuring depression, self-identity, and menopausal symptoms. Data were analyzed using t-test, ANOVA, Scheff$\acute{e}$ test, Pearson Correlation Coefficients, and Multiple Stepwise Regression. Results: Level of depression was low, self-identity was slightly high, and menopausal symptoms were relatively low in these middle-aged women. There were significant differences in depression by perceived health status and perceived economic status. Depression had a moderate negative correlation with self-identity (r=-.49, p<.001) and a moderate positive correlation with menopausal symptoms (r=.57, p<.001). Menopausal psychological symptoms were the factor most affecting depression and explained 37% of the variance in depression. A total of 51% of variance in depression was explained by menopausal symptoms (psychological and physical), self-identity, and perceived economic status. Conclusion: Thus, an effort to improve self-identity, especially a plan to attenuate menopausal psychological symptoms is needed to reduce depression.

Processing and Properties of RAINBOW Piezoelectric Actuator (RAINBOW 압전 액츄에이터의 제조와 물성)

  • Paik Jong-Hoo;Lim Eun-Kyeong;Kim Chang-il;Lee Mi-Jae;Jee Mi-Jung;Choi Byung-Hyun;Kim Sei-Ki
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
    • /
    • v.19 no.3
    • /
    • pp.222-227
    • /
    • 2006
  • RAINBOW(Reduced And Internally Biased Oxide Wafers) are a new class of high-displacement, piezoelectric actuator produced by selectively removing oxygen from one surface of ceramic using a high-temperature chemical reduction process. In this paper, RAINBOW actuator materials of $0.4Pb(Ni_{1/3}Nb_{2/3})O_3-0.6Pb(Zr_{x}Ti_{1-x})O_3$ ceramics were prepared. Its dielectric and piezoelectric properties were investigated in the vicinity of MPB. The piezoelectric properties showed the maximum value of ${\epsilon}r$ = 4871, $d_{33}$ = 610 ($10^{-12}$ m/V), $d_{31}$ = -299 ($10^{-12}$ m/V), $k_{33}$ = $71\%$, Qm = 70, in $0.4Pb(Ni_{1/3}Nb_{2/3})O_{3}-0.6Pb(Zr_{405}Ti_{595})O_3$ composition sintered at $1250^{\circ}C$. The strain - electric field characteristics of RAINBOW actuator were significantly improved comparison with the conventional bulk actuator. The prepared RAINBOW actuator showed about $390\;{\mu}m/100\;V$ displacement.

Benefits of procyanidins on gut microbiota in Bama minipigs and implications in replacing antibiotics

  • Zhao, Tingting;Shen, Xiaojuan;Dai, Chang;Cui, Li
    • Journal of Veterinary Science
    • /
    • v.19 no.6
    • /
    • pp.798-807
    • /
    • 2018
  • Several studies have reported the effect of absorption of procyanidins and their contribution to the small intestine. However, differences between dietary interventions of procyanidins and interventions via antibiotic feeding in pigs are rarely reported. Following 16S rRNA gene Illumina MiSeq sequencing, we observed that both procyanidin administration for 2 months (procyanidin-1 group) and continuous antibiotic feeding for 1 month followed by procyanidin for 1 month (procyanidin-2 group) increased the number of operational taxonomic units, as well as the Chao 1 and ACE indices, compared to those in pigs undergoing antibiotic administration for 2 months (antibiotic group). The genera Fibrobacter and Spirochaete were more abundant in the antibiotic group than in the procyanidin-1 and procyanidin-2 groups. Principal component analysis revealed clear separations among the three groups. Additionally, using the online Molecular Ecological Network Analyses pipeline, three co-occurrence networks were constructed; Lactobacillus was in a co-occurrence relationship with Trichococcus and Desulfovibrio and a co-exclusion relationship with Bacillus and Spharerochaeta. Furthermore, metabolic function analysis by phylogenetic investigation of communities by reconstruction of unobserved states demonstrated modulation of pathways involved in the metabolism of carbohydrates, amino acids, energy, and nucleotides. These data suggest that procyanidin influences the gut microbiota and the intestinal metabolic function to produce beneficial effects on metabolic homeostasis.

Effects of Psychological Acceptance and Social Support on Posttraumatic Growth in Stomach Cancer Patients (위암 환자의 심리적 수용, 사회적 지지가 외상 후 성장에 미치는 영향)

  • Cho, Hyun Mi
    • Journal of Korean Clinical Nursing Research
    • /
    • v.25 no.3
    • /
    • pp.265-274
    • /
    • 2019
  • Purpose: The purpose of this study was to identify the effects of psychological acceptance and social support on posttraumatic growth in stomach cancer patients. Methods: The questionnaires were administered from January 14 to February 11, 2015 to 123 subjects who had stomach cancer surgery six months prior. SPSS statistics 21.0 software was used to analyze the data for t-test, ANOVA, Pearson's correlations, Scheffé test and multiple regression analysis. Results: The results of this study are as follows: The major factors related to posttraumatic growth included gender (t=-2.72, p=.007), age (r=-.21, p=.016), having a religion (t=-3.40, p<.001), perceived importance of religion (r=.43, p<.001), seriousness of cancer diagnosis (r=.25, p=.005) and impact of cancer diagnosis (r=.32, p<.001). There were significant relationships between psychological acceptance (r=.18, p=.041) and social support (r=.32, p<.001) on posttraumatic growth. Significantly influential factors of posttraumatic growth were age (β=-.19, p=.021), perceived importance of religion (β=.41, p<.001) and family support (β=.29, p<.001), which together accounted for 36.5% of the variance in posttraumatic growth. Conclusion: The result of current study indicated that age, importance of religion, and family support influenced posttraumatic growth. Based on the findings of this study, developing nursing intervention programs focusing on increasing posttraumatic growth in stomach cancer patients is recommended.

Estimation of optimal nasotracheal tube depth in adult patients

  • Ji, Sung-Mi
    • Journal of Dental Anesthesia and Pain Medicine
    • /
    • v.17 no.4
    • /
    • pp.307-312
    • /
    • 2017
  • Background: The aim of this study was to estimate the optimal depth of nasotracheal tube placement. Methods: We enrolled 110 patients scheduled to undergo oral and maxillofacial surgery, requiring nasotracheal intubation. After intubation, the depth of tube insertion was measured. The neck circumference and distances from nares to tragus, tragus to angle of the mandible, and angle of the mandible to sternal notch were measured. To estimate optimal tube depth, correlation and regression analyses were performed using clinical and anthropometric parameters. Results: The mean tube depth was $28.9{\pm}1.3cm$ in men (n = 62), and $26.6{\pm}1.5cm$ in women (n = 48). Tube depth significantly correlated with height (r = 0.735, P < 0.001). Distances from nares to tragus, tragus to angle of the mandible, and angle of the mandible to sternal notch correlated with depth of the endotracheal tube (r = 0.363, r = 0.362, and r = 0.546, P < 0.05). The tube depth also correlated with the sum of these distances (r = 0.646, P < 0.001). We devised the following formula for estimating tube depth: $19.856+0.267{\times}sum$ of the three distances ($R^2=0.432$, P < 0.001). Conclusions: The optimal tube depth for nasotracheally intubated adult patients correlated with height and sum of the distances from nares to tragus, tragus to angle of the mandible, and angle of the mandible to sternal notch. The proposed equation would be a useful guide to determine optimal nasotracheal tube placement.

Acculturative Stress, Resilience, and Depression among Chinese Students in Korea (국내 중국유학생의 문화적응 스트레스와 적응유연성, 우울과의 관계)

  • Yoo, Myoung-Ran;Choi, Seon Young;Kim, Youn Mi;Han, Su-Jeong;Yang, Nam-Young;Kim, Hee Kyung;Chang, Hae Kyung;Lee, Mi-Ra;Son, Youn-Jung
    • The Journal of Korean Academic Society of Nursing Education
    • /
    • v.19 no.3
    • /
    • pp.320-329
    • /
    • 2013
  • Purpose: The purpose of this study was to identify resilience's mediating effect between acculturative stress and depression among Chinese students in Korea. Methods: Between February and May 2012, 276 Chinese students from 3 universities located in Chungnam province participated in the current study using a questionnaire survey. Data was analysed using SPSS 18.0 program. Results: The mean score of acculturative stress, resilience, and depression was 82.7, 129.0, and 15.6 respectively. The acculturative stress was significantly related to perceived health status (F=10.57, p<.001), TOPIK(t=7.55, p=.006) and the major(F=2.87, p=.024). Resilience was related to the race(F=13.49, p<.001), perceived heath status (F=10.57, p<.001), tuition(F=8.52, p<.001), and level of Koran language(F=5.91, p=.003). Resilience correlated to acculturative stress (r=-0.21, p<.001) and depression(r=-0.48, p<.001) by showing a mediating effect between accuturative stress and depression. Conclusion: In order to improve resilience as a mediating factor with depression of Chinese students in Korea, we suggest the development various programs about external supporting programs.

Influence of Critical Thinking and Empathy on Resilience of Senior Nursing Students (졸업학년 간호대학생의 비판적 사고 성향과 공감역량이 회복 탄력성에 미치는 영향)

  • Baek, Kyoung-Hwa;Yang, Young-Mi;Cho, Mi-Ock
    • Journal of Convergence for Information Technology
    • /
    • v.11 no.7
    • /
    • pp.57-66
    • /
    • 2021
  • This study is a descriptive research study to investigate the effects of critical thinking and empathy on resilience of nursing students. The subjects of this study were 234 nursing students in the 4th grade and the data were collected from June 3 to 19, 2019. Data was processed by descriptive statistics, t-test, correlation analysis, and multiple regression method. As a result of the study, critical thinking and empathy showed a significant positive relationship with resilience. Critical thinking and empathy were factors that influence the resilience of nursing students and the resilience was explained as 70.3%. Therefore, in order to increase the resilience of nursing students it is considered that an education program that strengthens internal factors can cultivate critical thinking and empathy skills is necessary.

The Relationship between the Optimistic Bias about Cancer and Cancer Preventive Behavior of the Korean, Chinese, American, and Japanese Adult Residing in Korea (한국에 거주하는 한.중.미.일 성인의 암에 대한 낙관적 편견과 암 예방행위 간의 관계)

  • Lee, Sul-Hee;Ham, Eun-Mi
    • Journal of Korean Academy of Nursing
    • /
    • v.40 no.1
    • /
    • pp.52-59
    • /
    • 2010
  • Purpose: This study was conducted to provide basic data for developing education and health promotion programs for the prevention of cancer by identifying the relation between optimistic bias about cancer and cancer preventive behavior in Korean, Chinese, American, and Japanese residents in Korea. Methods: Using a questionnaire administered by the researcher, data were collected from a convenience sample of 600, 19 to 64-yr-old male and female Korean, Chinese, American, and Japanese residents in Korea. Data was collected between February 6 and 28, 2009. Results: Scores for optimistic bias about cancer by nationality were: Koreans, -1.03; Chinese, -0.43; Americans, -0.23; and Japanese, 0.05. The cancer preventive behavior scores were: Koreans, 43.17; Chinese, 71.84; Americans, 71.71; and Japanese, 73.97. Optimistic bias about cancer and cancer preventive behavior showed a significantly positive correlation in all participants: Koreans (r=.223, p=.006); Chinese (r=.178, p=.029); Americans (r=.225, p=.006); and Japanese (r=.402, p<.001). Conclusion: The greater the optimistic bias about cancer is, the lower the cancer preventive behavior. The findings suggest that nursing interventions are needed to reduce optimistic bias about cancer and to form a positive attitude towards cancer prevention because an optimistic bias about cancer adversely affects cancer preventive behavior.

Factors Influencing Work-related Burnout of Nurses and Caregivers in Nursing Homes (노인요양시설 간호사와 요양보호사의 직무관련 소진 영향요인)

  • Lee, Young-Mi;Kim, Sung-Ja;Kim, Kisook
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.14 no.4
    • /
    • pp.1755-1764
    • /
    • 2013
  • This study was to identify factors influencing the job-related burnout of the nurses and caregivers in nursing homes. The participants in this study were 188 who were working as nurses (77) and caregivers (111) at five nursing homes in Seoul and Gyeonggi Province. Collected data were analyzed in independent t-test, Pearson's correlation coefficients, multiple stepwise regression using IBM SPSS Statistics 19.0. The nurse's job-related burnout was positively correlated with job-satisfaction(r=.333, p=.003), and stress(r=.484, p<.001), whereas caregiver's job-related burnout was positively correlated with stress(r=.458, p<.001). The factor influencing on nurse's job-related burnout was interpersonal relation stress and this factors explained 27.0% of the variance. In case of the caregivers, work-related stress was a factor influencing on job-related burnout and it explained 21.2% of the variance. On the basis of the results in this study, the improvement of working conditions, and the development of stress management program should be considered systematically.

Factors Affecting the attitude to death of Social Welfare Students (사회복지전공 대학생의 죽음에 대한 태도의 영향요인)

  • Kim, Bo-Mi
    • Journal of Digital Convergence
    • /
    • v.19 no.11
    • /
    • pp.545-553
    • /
    • 2021
  • This research was conducted to examine the attitude to death, and identify factors influencing attitude to death, in social welfare students. Data were collected from 179 social welfare students. in two universities. Data were collected from April to June 2021 using structured questionnaires. Data collected were analyzed by descriptive statistics, t-test, ANOVA, Pearson correlations, and multiple regression analysis. The results indicated that meaning in life(r=.34, p=.001) had a significant positive association with attitude to death. And life satisfaction(r=.61, p<.001) and resilience(r=.65, p<.001) were positively correlated with attitude to death, The significant predictors of attitude to death, were grade(β=.21, p=.002) and life satisfaction(β=.22, p=.013), explaining 20.2% of the variance. Based on the study results, we suggest that it is necessary to develop counseling and attitude to death programs that can positively change the attitude of social welfare students