• 한국지하수토양환경학회:학술대회논문집
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• 한국지하수토양환경학회 2004년도 총회 및 춘계학술발표회
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• pp.447-450
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• 2004

This study was conducted to characterize groundwater and river-water fluctuations at a riverbank filtration site in Daesan-myeon adjacent to the Nakdong River, using time series analysis. Water levels from six observation wells from January 2003 to October 2003 were measured. The autocorrelation analysis indicates that the wells are divided into three groups: group 1 represents strong linearity and memory, group 2 intermediate linearity and memory, and group 3 weak linearity and memory. The analysis indicates that groundwater levels in different monitoring wells vary in response to river-water levels, groundwater withdrawal and seasonal rainfall. Cross-correlation was also divided into three groups. Group 1 shows the highest cross-correlation function (0.49 - 0.54) for a lag time of 0 hours, group 2 intermediate cross-correlation function (0.34 - 0.45), and group 3 the lowest cross-correlation function (0.23 - 0.25). Different cross-correlation functions among the 3 groups are interpreted as an effect of tile distance from the river to the pumping wells.

• 한국통신학회논문지
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• 제24권9A호
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• pp.1442-1450
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• 1999

본 논문에서는 MPEG-2 비디오 부호화기에서의 프레임 메모리 하드웨어 구현을 위한 DRAM의 효율적인 메모리 맵과 이에 따른 하드웨어 구조를 제안한다. 논문에서 제시된 메모리 맵은 DRAM 사용 시간과 대역폭을 줄임으로써 시스템의 성능을 개선할 수 있도록 설정되었고, 개발된 하드웨어는 MPEG-2 비디오 부호화기에 구성된 타모듈과 인터페이스를 위해 하드웨어는 VHDL을 이용하여 구현하였으며, $0.5\mu\textrm{m}$, VTI, ASIC 라이브러리인 camn5a3을 이용하여 합성하였다. 개발된 하드웨어에 대한 RT (register transfer) 수준 및 게이트 수준의 검증을 위해 VHDL 시뮬레이터와 로직 합성 툴을 사용하였고, 추후 성능 개선과 기능 검증을 위해서 하드웨어 에뮬레이터를 개발하였다. 구현된 하드웨어 MPEG-2의 MP@ML에서 요구하는 전송률로 데이터를 채널에 전송할 수 있도록 하였다.

• 약학회지
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• 제36권1호
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• pp.56-65
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• 1992

The present study examined the effects of carbon monoxide (CO) intoxication and aging on learning and memory deficit in young($5{\sim}8$ weeks) and aged($52{\sim}66$ weeks) mice, using the step down and step through passive avoidance failure techniques. We also investigated the effects of ginseng saponins on memory deficit. Significant decrease in memory registration, retention and retrieval function in young mice and decrease in memory registration and retention function in aged mice were observed. Normal young mice were apt to perform to a great degree of passive avoidance response than normal aged mice, but there was no difference between both groups by CO exposure. Administration of ginseng saponins showed an improvement on passive avoidance failure induced by CO exposure.

• 감성과학
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• 제5권1호
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• pp.79-90
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• 2002

기억은 상황인식을 개발하고 유지하는 데 중요한 역할을 한다. 본 연구에서는 비행상황 인식의 민감도에 영향을 주는 기억과정들이 조종사의 전문성 정도에 따라 어떻게 다른지를 조사하였다. 실험 1에서는 조종사가 상황정보를 회상하기 위해 사용하는 여러 기억과정들을 비교하였다. 즉, 조종실 계기판에 제시되는 상이한 형태(공간적 및 언어적)의 상황정보에 관한 조종사의 기억을 즉각회상과 지연 회상법으로 평가하였다. 실험 2에서는 조종사의 상황인식 민감도를 측정하였고, 그 민감도와 실험 1에서 수집한 여러 회상기억 측정치들과의 상관관계를 조사하였다. 두 실험결과를 요약하면, 전문성 효과가 상황정보의 활동기억보다는 장기기억에서 나타났고, 상황인식 민감도를 높이는 데 요구되는 상황정보의 기억표상이 전문성 정도에 따라 달랐다. 실험결과의 이론적 설명이 심리학의 전문성 이론을 중심으로 논의되었다.

• 생명과학회지
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• 제9권5호
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• pp.548-555
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• 1999

Long-term effects of Ganoderma lucidum (GL) on memory and oxidative stress of senescence-accelerated mice (SAM) were investigated. Senescence-resistant (R1) and prone (P8) strains of SAM were fed GL diets, premixed with low (20 mg/kg/day, T1) or high (200 mg/kg/day, T2) levels of GL powder for 9 months starting from young (3 months of age) or for 5 months starting from old (7 months of age). After the final feeding at 12 months of age, all animals were subjected to passive avoidance test for the evaluation of memory function. In addition, the changes in hepatic thiobarbituric acid-reactive substance (TBARS) and glutathione were analyzed. SAMP8 fed GL diets from old age (7 months) exhibited the improvement of memory, although GL rather inhibited the memory function of both SAMR1 and SAMP8 mice fed diets from young (3 months of age). Hepatic TBARS contents were decreased in SAMP8 fed high GL diet for 9 months and in SAMR1 fed low GL diet for 5 months. Hepatic glutathione content was also remarkably increased in SAMR1 following both feeding periods, and less extent in SAMP8 fed diet for 5 months of age. Taken together, it is proposed that GL extracts may play an anti-aging role through antioxidant action, and thereby may improve the senescence-related memory dysfunction.

• JSTS:Journal of Semiconductor Technology and Science
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• 제2권3호
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• pp.170-172
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• 2002

The epilayer of vertically stacked, self-assembled InAs Quantum Dots (QDs)was grown by MBE with solid sources in non-cracking K-cells, and the sample was fabricated to a FET structure using a conventional technology. The device characteristic and performance were studied. At 77K and room temperature, the threshold voltage shift values are 0.75V and 0.35 V, which are caused by the trapping and detrapping of electrons in the quantum dots. Discharging and charging curves form the part of a hysteresis loop to exhibit memory function. The electrical injection of confined electrons in QDs products the threshold voltage shift and memory function with the persistent electron trapping, which shows the potential use for a room temperature application.

• Steel and Composite Structures
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• 제38권4호
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• pp.447-462
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• 2021

In this work, we consider a problem in the context of thermoelectric materials with memory-dependent derivative for a half space which is assumed to have variable thermal conductivity depending on the temperature. The Lamé's modulii of the half space material is taken as a function of the vertical distance from the surface of the medium. The surface is traction free and subjected to a time dependent thermal shock. The problem was solved by using the Laplace transform method together with the perturbation technique. The obtained results are discussed and compared with the solution when Lamé's modulii are constants. Numerical results are computed and represented graphically for the temperature, displacement and stress distributions. Affectability investigation is performed to explore the thermal impacts of a kernel function and a time-delay parameter that are characteristic of memory dependent derivative heat transfer in the behavior of tissue temperature. The correlations are made with the results obtained in the case of the absence of memory-dependent derivative parameters.

• 셀메드
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• 제13권14호
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• pp.14.1-14.9
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• 2023

Administration of Scopolamine can be considered a psychopharmacological model of Alzheimer's disease (AD). We made an animal model of Alzheimer's disease (AD) by administering Scopolamine to Blab/c mice. In this study, we investigated the effects of Resplex Alpha on memory impairment and cognitive function in mice in a mouse animal model of Scopolamine-induced memory impairment. Through Y-mazed and passive avoidance behavioral assays, we observed that Resplex Alpha recovered Scopolamine-induced short-term memory and cognitive functions. The results of our study imply that Resplex Alpha may be beneficial in the prevention of Alzheimer's disease (AD).

• Journal of Ginseng Research
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• 제48권1호
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• pp.59-67
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• 2024

Background: Alzheimer's disease (AD) has memory impairment associated with aggregation of amyloid plaques and neurofibrillary tangles in the brain. Although anti-amyloid β (Aβ) protein antibody and chemical drugs can be prescribed in the clinic, they show adverse effects or low effectiveness. Therefore, the development of a new drug is necessarily needed. We focused on the cognitive function of Panax ginseng and tried to find active ingredient(s). We isolated panaxcerol D, a kind of glycosyl glyceride, from the non-saponin fraction of P. ginseng extract. Methods: We explored effects of acute or sub-chronic administration of panaxcerol D on cognitive function in scopolamine- or Aβ_25-35 peptide-treated mice measured by several behavioral tests. After behavioral tests, we tried to unveil the underlying mechanism of panaxcerol D on its cognitive function by Western blotting. Results: We found that pananxcerol D reversed short-term, long-term and object recognition memory impairments. The decreased extracellular signal-regulated kinases (ERK) or Ca²⁺/calmodulin-dependent protein kinase II (CaMKII) in scopolamine-treated mice was normalized by acute administration of panaxcerol D. Glial fibrillary acidic protein (GFAP), caspase 3, NF-kB p65, synaptophysin and brainderived neurotrophic factor (BDNF) expression levels in Aβ_25-35 peptide-treated mice were modulated by sub-chronic administration of panaxcerol D. Conclusion: Pananxcerol D could improve memory impairments caused by cholinergic blockade or Aβ accumulation through increased phosphorylation level of ERK or its anti-inflammatory effect. Thus, panaxcerol D as one of non-saponin compounds could be used as an active ingredient of P. ginseng for improving cognitive function.

• 한국엔터테인먼트산업학회논문지
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• 제13권6호
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• pp.277-286
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• 2019

본 연구의 목적은 전산화 인지재활과 전통적 인지훈련이 경도 외상성 뇌손상 환자의 작업기억과 실행기능에 미치는 영향을 탐색하기 위함이다. 본 연구는 재활병원에서 재활치료를 받는 경도 외상성 뇌손상 환자 20명이 참여하였다. 대상자들은 실험군 10명과 대조군 10명으로 할당되었다. 실험군은 전산화 인지재활과 전통적인 인지훈련을 30분씩 60분을 받았으며, 대조군은 전통적인 인지훈련을 60분 수행하였다. 두 군은 하루 60분, 주 5회, 4주 동안 배정된 훈련을 수행하였다. 작업기억과 실행기능을 평가하기 위하여, 숫자외우기 검사(정방향, 역방향)와 MVPT-3의 시각기억, 그리고 선추적 검사와 스트룹 검사 A와 B를 중재 전과 후에 실시하였다. 두 군 간 변화량 비교에서 실험군은 대조군보다 시각기억과 스트룹 검사 A에서 유의하게 더 큰 향상을 보였다. 이러한 결과는 전산화 인지재활과 전통적 인지훈련이 전통적인 인지훈련보다 작업기억과 실행기능에 긍정적인 변화를 제공할 수 있음을 시사한다.