• Bulletin of the Korean Chemical Society
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• v.30 no.9
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• pp.2135-2137
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• 2009

• BMB Reports
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• v.43 no.2
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• pp.133-139
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• 2010

We have performed analyses using ancient DNA extracted from 25 excavated human bones, estimating around the 1st century B.C. Ancient human bones were obtained from Nukdo Island, which is located off of the Korean peninsula of East Asia. We made concerted efforts to extract ancient DNA of high quality and to obtain reproducible PCR products, as this was a primary consideration for this extensive kind of undertaking. We performed PCR amplifications for several regions of the mitochondrial DNA, and could determine mitochondrial haplogroups for 21 ancient DNA samples. Genetic information from mitochondrial DNA belonged to super-haplogroup M, haplogroup D or its sub-haplogroups (D4 or D4b), which are distinctively found in East Asians, including Koreans or Japanese. The dendrogram and principal component analysis based on haplogroup frequencies revealed that the Nukdo population was close to those of the East Asians and clearly distinguished from populations shown in the other regions. Considering that Nukdo is geologically isolated in the southern part of the Korean peninsula and is a site of commercial importance with neighboring countries, these results may reflect genetic continuity for the habitation and migration of ethnic groups who had lived in a particular area in the past. Therefore, we suggest that phylogenetic analyses of ancient DNA have significant advantages for clarifying the origins and migrations of ethnic groups, or human races.

• Korean Journal of Medicinal Crop Science
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• v.19 no.2
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• pp.97-102
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• 2011

In this study, whitening activity of Lithospermum erythrorhizon extracts were investigated according to several extraction processes: water extraction at $100^{\circ}C$ (WE100) and $60^{\circ}C$ (WE60), 70% ethyl alcohol extraction (EE) and ultra high pressure extraction (HPE) at 500 MPa for 30 minutes at $60^{\circ}C$. The extracts from ultra high pressure extraction showed the highest tyrosinase inhibition and melanogenesis inhibition activities as 52% and 79.5%, respectively, in adding $1mg/m{\ell}$ than others extraction processes. HPE extracts also showed the strong reducing power as 3.19 that absorbance at 450 mm. The contents of polyphenol in WE100, we measured as $10.1{\mu}g/m{\ell}$ in adding $1mg/m{\ell}$. Extracts have a high total flavonoid contents by HPE as $4.1{\mu}g/m{\ell}$ at $1mg/m{\ell}$. We can conclude that better whitening activity of extracts from high pressure extraction was due to high antioxidant activities which could be extracted by higher polyphenol and flavonoid contents in HPE than others.

• Journal of Society of Preventive Korean Medicine
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• v.4 no.2
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• pp.285-293
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• 2000

Objectives: We have accomplished a clinical research about counteracting the pesticides intoxication using oriental medical method and treatment. And we observed the preventive effect of Gamdu-tang(甘豆湯) to intoxication of Organophosphorus Insecticides. Material and Methods: The subjects were 8 volunteers who were healthy and not taking medications. we observed change of cholinesterase(ChE) activity in serum of them after exposed to pesticides Results and Conclusions : In this study of the preventive effects of Gamdu-tang(甘豆湯) on the intoxication of Organophosphate Insecticides, we evaluated that the decreasing value of ChE activity after spraying insecticides of Gamdu-tang medication group was smaller than non-medication group, but it was less significant(P>0.05 P<0.1). We had a difficult to gather participant in this study, so it's necessary for us to get together more larger group in the next study.

• Journal of Korean Medical classics
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• v.33 no.4
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• pp.67-81
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• 2020

Objectives : This research aims to suggest a automatic data extract method for herbal formula combinations from medical classics' texts. Methods : This research was carried out by using Access of Microsoft Office 365 in Windows 10 of Microsoft. The subject text for extraction was 『Euijongsonik』. Using data sets of herb and dosage terminology, herbal medicinals and their dosages were extracted. Afterwards, using the position value of the character string, the formula combinations were automatically extracted. Results :The PC environment of this research was Intel Core i7-1065G7 CPU 1.30GHz, with 8GB of RAM and a Windows 10 64bit operation system. Out of 6,115 verses, 19,277 herb-dosage combinations were extracted. Conclusions : In this research, it was demonstrated that in the case of classical texts that are available as data, knowledge on herbal medicine could be extracted without human or material resources. This suggests an applicability of classical text knowledge to clinical practice.

• Nuclear Engineering and Technology
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• v.56 no.8
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• pp.3268-3275
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• 2024

Isotopes are an important aspect of modern medical and scientific research and cyclotron-based isotope production is of particular interest. Cooling devices are required to manage the heat generated by high-energy particle beams to ensure that they can be delivered securely. However, there is considerable scope for further advancements in the design of cooling systems. Therefore, this study uses simulations to investigate the design of innovative cooling systems. Various designs and materials are considered using a variable four-sector collimator and various particle-beam conditions. Thus, new design principles and material and structural optimization strategies are proposed, which can be used to improve the stability and efficiency of isotope production. The results provide insight into technical challenges and may contribute toward advances in medical diagnostics, radiotherapy, and fundamental scientific research. In particular, they can guide the development of isotopebased technologies in nuclear medicine.

• Journal of Arbitration Studies
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• v.26 no.4
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• pp.111-128
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• 2016

Trade between nations has been considered as exchange for material things. According to recent changes in the paradigm of global trade, trade is shifting focus on the exchange of an immaterial being. Among them, the service sector is growing fast and the health service has shown exceptional growth as the healthcare market is consistently expanding. It is also part of the global service targeting people all around the world. People visiting other countries for medical service tend to spend more money and stay longer than a traveler. For these reasons, global medical service is in the spotlight as a promising and higher value-added business. The global medical service industry has been developed around Asia, specifically Thailand, Singapore, India, etc. Compared to them, Korea has come late into the market of global healthcare and the Korean government is striving to attract foreign patients. Nevertheless, there is a lack of effort to make foreign patients visiting Korea revisit Korea. Regarding foreign patients' medical disputes, these are not yet a problem officially; however, the government cannot leave the matter as it is. Medical dispute related with foreign patients is a highly complex issue due to different languages, nationalities, cultures, etc. Particularly, Korea's medical tourism is developed with Chinese visiting Korea for plastic surgery and cosmetic procedure. Thus, the Korean medical tourism market can be crowded with a lot of minor medical agencies, so-called brokers, getting foreign patients connected to the medical institutions. Consequently, Korea has received a large number of complaints and dissatisfaction. No one can predict and know what's supposed to happen in the future. Efforts of the Korean government and medical institute attracting foreign patients could be in vain. In order to take a step forward, this paper will do research on present conditions and look for strategies of improving this industry, focusing on the part of medical agency and contributing to the improvement of the Korean medical tourism industry.

• Journal of Korean Medical classics
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• v.34 no.2
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• pp.1-22
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• 2021

Objectives : A transition course of 'Introduction to Clinical Korean Medicine' was developed to meet the demands for better preparation for clinical application of Korean Medicine within the curriculum. A Korean Medical Classics curriculum reflecting such demands was newly designed. Methods : Based on the 'Introduction to Clinical Medicine(ICM)' course of the Medical School curriculum that follows the medical education guideline, the 'Introduction to Clinical Korean Medicine(ICKM)' course was designed and developed. The role of Korean Medical Classics was suggested in the process. Results : In the following course, Korean Medical diagnosis, diagnostics, patient intake methods reflecting the Korean Medical diagnostic system, clinical skills, basic skills, treatment planning, patient education, etc. are included. Faculty members of the basic sectors of the Korean Medical school will participate in this curriculum, of which a head will be appointed to overlook the curriculum. In the case of Korean Medical Classics, previous learning outcomes need to be reorganized based on clinical expression while clinical case studies need to be added to course material. A more active approach utilizing new pedagogic strategies and teaching methods should be taken. Conclusions : The Korean Medical Classics curriculum could effectively take on the introductory role to clinical Korean Medicine, successfully strengthening the connection between the basic and clinical Korean Medicine to improve learners' satisfaction.

• The Journal of Korean Medical History
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• v.24 no.1
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• pp.1-8
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• 2011

As the value of living a complete life has spread, the importance of elderly education as a part of continuing education is ever increasing. As much as the bodily health, the activity to prevent dementia or healthy brain is being emphasized, the math utilizing traditional material was suggested to devise the curriculum appropriate for the emotional/cognitive level of the elderly. This could induce interests of the elderly, and ultimately improved the concept of self-consciousness and self-esteem. Also, a plan for effective application of such 'silver math' should be prepared, and the execution of a fusion study for a medical approach of its effects is proposed.

• Journal of radiological science and technology
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• v.10 no.1
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• pp.25-29
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• 1987

To compensate density of abnormal lung field for density of normal lung field, used each cellulose paper calculated sensitometry and contrast. As apply clinic part to the result: We are able to compensate density of abnormal lung that is pleural effusion atelectasis, etc for normal lung. We believe this method is good one because the method is simple to change exposure and the material is cheap enough to be accessible to every one and easily buyable and we need not be afraid of loss of image quality.