• Title/Summary/Keyword: medical exchange

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Regulation of Magnesium Release by cAMP during Chemical Hypoxia in the Rat Heart and Isolated Ventricular Myocytes

  • Kim, Jin-Shang;Scarpa, Antonio
    • The Korean Journal of Physiology and Pharmacology
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    • v.3 no.1
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    • pp.59-68
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    • 1999
  • Chemically induced hypoxia has been shown to induce a depletion of ATP. Since intracellular free $Mg^{2+}\;([Mg^{2+}]_i)$ appears to be tightly regulated following cellular energy depletion, we hypothesized that the increase in $[Mg^{2+}]_i$ would result in $Mg^{2+}$ extrusion following hormonal stimulation. To determine the relation between $Mg^{2+}$ efflux and cellular energy state in a hypoxic rat heart and isolated myocytes, $[Mg^{2+}]_i,$ ATP and $Mg^{2+}$ content were measured by using mag-fura-2, luciferin-luciferase and atomic absorbance spectrophotometry. $Mg^{2+}$ effluxes were stimulated by norepinephrine (NE) or cAMP analogues, respectively. $Mg^{2+}$ effluxes induced by NE or cAMP were more stimulated in the presence of metabolic inhibitors (MI). Chemical hypoxia with NaCN (2 mM) caused a rapid decrease of cellular ATP within 1 min. Measurement of $[Mg^{2+}]_i$ confirmed that ATP depletion was accompanied by an increase in $[Mg^{2+}]_i.$ No change in $Mg^{2+}$ efflux was observed when cells were incubated with MI. In the presence of MI, the cAMP-induced $Mg^{2+}$ effluxes were inhibited by quinidine, imipramine, and removal of extracellular $Na^+.$ In addition, after several min of perfusion with $Na^+-free$ buffer, a large increase in $Mg^{2+}$ efflux occurred when $Na^+-free$ buffer was switched to 120 mM $Na^+$ containing buffer. A similar $Mg^{2+}$ efflux was observed in myocytes. These effluxes were inhibited by quinidine and imipramine. These results indicate that the activation of $Mg^{2+}$ effluxes by hormonal stimulation is directly dependent on intracellular $Mg^{2+}$ contents and that these $Mg^{2+}$ effluxes appear to occur through the $Na^+-dependent\;Na^+/Mg^{2+}$ exchange system during chemical hypoxia.

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Groping for the Direction of Development from the Comparison of Traditional Medicine between Korea and Vietnam (한국과 베트남의 전통의학 현황 비교를 통한 발전 방향 모색)

  • Kwon, Ji-Hye;Lee, Si-Woo;Yoo, Jong-Hyang
    • The Journal of the Korea Contents Association
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    • v.15 no.2
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    • pp.370-376
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    • 2015
  • The aim of this study was to survey the recognition and utilization of traditional medicine among the clinical doctors who working at traditional medicine hospital in Vietnam. The survey was conducted for 3month from September to November, 2012. As a result, the highest recognized traditional medicine was acupuncture(91.4%) and herbal medicine(86.1%). Almost of respondents had ever used acupuncture(99.4%), massage or acupressure(97.6%) and herbal medicine(95.3%) in daily clinical practice. And commonly treated health problem was neurological and psychological disease(23.5%). The most used diagnostic methods were tongue diagnosis and pulse diagnosis(97.6%). This survey will help to explore the point of contact between the traditional medicine of Vietnam and Korea. This survey results could be used as basic materials to actively approach traditional medical markets through international exchange and cooperation in the future.

A Study on Nursing Diagnoses and Nursing Intervention Classification -focused on Home Health Care Clients- (간호진단과 중재분류에 관한 조사연구 -가정 간호 대상자를 중심으로-)

  • 김조자;최애규;김기란;송희영
    • Journal of Korean Academy of Nursing
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    • v.29 no.1
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    • pp.72-83
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    • 1999
  • The purpose of this study was to classify, from collected home health care records data, nursing diagnoses according to the NANDA system and nursing interventions according to the NIC system, and to link nursing interventions to nursing diagnoses. For this study, 101 home health care records of clients seen between September, 1994 and November, 1996 at Yonsei Medical Center, Seoul, were analyzed. The results of this study are summarized as follows : 1. The most frequent nursing diagnoses were ‘Risk for infection’ and ‘Altered nutrition : Less than body requirements’, then ‘Impaired skin intergrity’ and ‘Ineffective airway clearance’ in the Exchange pattern of NANDA nine human response patterns. 2. The most frequent nursing interventions were the interventions in the Physiological : Complex domain, there were 690(50.7%) interventions among a total 1347 interventions. This results corresponds to Yom, Young Hee(1995)’s research, both Korean and U.S. nurses used the interventions in the Physiological : Complex do main most often on a daily basis. And respiratory nursing interventions were most frequent because 32.7% of the subjects were respiratory patients. 3. The next step was to link the nursing interventions to nursing diagnoses. The most frequent nursing diagnosis was ‘Risk for infection’ and 19 interventions for ‘Risk for infection’ were used 267 times. Then 14 interventions for ‘Impaired skin integrity’ were used 258 times, 12 interventions for ‘Ineffrective airway clearance’ were used 193 times, 12 interventions for ‘Altered nutrition : Less than body requirements’ were used 122 times, 10 interventions for ‘Activity intolerance’ were used 75 times, and 11 interventions for ‘Knowledge deficit’ were used 52 times. 4. The use of standardized classification in the areas of nursing diagnoses and nursing interventions facilitates clinical decision making and prompt nursing activity, and so enhances the effectiveness of nursing care.

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Data Overlap Avoidance Algorithm Based on Traffic Scheduling (트래픽 스케줄링 기반 데이터 중복 회피 알고리즘)

  • Choi, Myeong Soo;Kim, Beom-Mu;Lee, Seong Ro
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39C no.9
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    • pp.841-851
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    • 2014
  • Wireless technologies sharing the same frequency band and operating in the same environment often interfere with each other, causing severe decrease in performance. In this paper, we propose a algorithm based on traffic scheduling techniques that mitigate interference between different wireless systems operating in the 2.4-GHz industrial, medical, and scientific band. In particular, we consider IEEE 802.11 wireless local area networks (WLANs) and Bluetooth data transfer, showing that the proposed algorithms can work when the two systems are able to exchange information as well as when they operate independently of one another. Results indicate that the proposed algorithm remarkably mitigate the interference between the WLAN and Bluetooth technologies at the expense of a small additional delay in the data transfer.

The Phenomenological Study of School health practice experience of Nursing Students (학교 보건 실습 경험에 관한 현상학적 연구)

  • Woo, Seon-Hye;Park, Young-Suk
    • Research in Community and Public Health Nursing
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    • v.6 no.2
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    • pp.161-172
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    • 1995
  • This study was conducted to have better understanding of the students' experience in field practice by school health practice experience. The study subjects were 40 nursing students working in department of nursing K Univ. in C city. This study was approached by phenomenological method. Collected data were analyzed by Colaizzi's method. The results were from the protocol 980 significant statements and organized into 240 formulated meanings. From formulated meaning 89 themes were identified, organized into 18 them clusters, and then into 16 categories. The nursing students took part in the practice with (expectation and readiness) different from those of the clinical practice, expressed wonder at the school which had progressed much more than their primary schools used to be. They said that they began to feel (Fatigue and stress), and that experienced tension for the lack of nursing knowledge and skill during the health education and clinical treatment activity. In addition, they experienced 'ambivalence of satisfaction and something wanted', that is to say, they could have done better by means of video education and health education. The 10-day-school health practice brought about the change in( the image of teacher) and (cognition about the nursing teacher's role), made the students have(love to the client) and (desire to be nursing teacher), and then turned out experience benefical enough to be expressed 'satisfaction' However, they pointed out many problems in (School Eniviroment), (Clinic), (Physical assessment), (Recording and reporting), so they had a chance to apply the school nursing process to the school. The professor should play the role of promoting the learning through the field practice and providing the stimulant of learning to help the learner get as much from the field situation as they could. Therefore, I suggest that the students always have a chance to exchange actual affairs and educational study, and that the concrete discussion and continuous cooperation be done. The professors should keep doing their best to find the way to professors should keep doing their best to find the way to promote the ability of thinking through the process the learners experienced themselves.

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A Study on the Improvement of Shared Space for Aging society (고령사회 주민공유공간의 발전방향에 관한 연구)

  • Kim, Hye-Jin;Lee, Yeun-Sook;Yoon, Hye-Gyoung
    • Proceedings of the Korean Institute of Interior Design Conference
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    • 2008.05a
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    • pp.214-219
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    • 2008
  • The aging of the population has been in process all over the world including most of advanced countries. With the improvement of living standards and medical technology due to the growth and development of the modern industrial society, the continuous Increase of the average lifespan has led to an abrupt growth in the population ratio of the aged. The senescence is the period where both physical and mental functions get dwindled, and due to a loss of roles in a society and a weakened social bond, the elderly people feel often neglected and isolated. Consequently, the elderly people spend a lot of time in their houses. As this means that the elderly gets higher possibility to stay within housing units and housing complex environment, residents' public space needs to be developed within the housing complex for them. Therefore, constructive programs and plans are required for the elderly who experience distance constraint because of corporal aging, for them to sustain community activities within their housing environment. Contrary to them in the 20th century, the elderly living in the nowadays informational society tend to enjoy their leisure times with arts and cultures and underscore the significance of social exchange under diverse possibility and sustainableness. Thus, it is important to preserve those circumstances to provide continuously them. Thus, the purpose of this paper is to grope a growth direction of residents' public space for the elderly to include them to their community through a socially integrated way by grasping present condition of apartment residents' public space's facilities and to be used practically as a basic housing environment data to raise quality of community life.

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Purification of Antithrombotic Material from Auricularia auricular-judae Extracts and Its Antithrombotic Activity (목이버섯 추출물로부터 항혈전물질의 정제와 항혈전효과)

  • Park, Young-Seo;Choi, Hyuk-Joon;Choi, Tae Hyun
    • Food Engineering Progress
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    • v.13 no.4
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    • pp.326-334
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    • 2009
  • Blood coagulation and aggregation of platelet are crucial events in the pathogenesis of various ischemic diseases. The substance which can prevent blood coagulation and platelet aggregation was extracted from wood ear mushroom (Auricularia auricular-judae) and its anticoagulation activity was investigated. The dried A. auricular-judae was extracted with 0.1 N NaOH and its supernatant was further extracted with methanol and ethanol followed by $H_{2}O$. The resulting methanol soluble fraction showed significant antithrombotic activity in activated partial thromboplastin time, thrombin time, and prothrombin time assays with values of 100, 124, and 54 sec, respectively. This active substance was purified with DEAE-Sepharose CL6B and Sephacryl 400-HR and was found to be polysaccharide with the average molecular weight of over 150 kDa. This polysaccharide was xyloglucomannan of which the main component was mannose, and its anticoagulant activity was mostly mediated by inhibition of thrombin activity.

Network Analysis of Readers' Countries of Korean Studies using Mendeley Co-readership Data (Mendeley co-readership 정보를 활용한 한국 관련 논문의 글로벌 독자 국가 네트워크 분석)

  • Cho, Jane;Park, Jong-Do
    • Journal of the Korean Society for information Management
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    • v.35 no.4
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    • pp.107-124
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    • 2018
  • Mendeley readership data could be used to understand how research outcome be spent outside of academia in multi way. So it could be utilized to understand unknown world which citation rate could not explain still now. This study, by conducting a country network analysis using Mendeley's co readership data about articles of Korea related research, clusters countries that share common academic interest. As a result, the US and other advanced countries in all fields showed high overall and regional centrality, indicating that they have overall cooperation and potential for exchange of Korea related studies. Some developing countries have shown high regional centrality and are linked to common academic interests. In the medical and social sciences, the OECD and developing countries have formed a separate group of readers, and the engineering sector has been characterized by emerging developing countries as a large community of readers. In addition, engineering science field has shown that network density is relatively high, so there might be high possibility of academic exchanges, knowledge dissemination and cooperation among countries.

Clinical effects of veno-venous extra-corporeal membrane oxygenation for acute myocardial infarction (급성심근경색 환자에게 적용된 정맥-정맥 체외막산화기의 임상 효과)

  • Kim, Su Wan;Seong, Gil Myeong;Lee, Jae-Geun
    • Journal of Medicine and Life Science
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    • v.15 no.2
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    • pp.108-111
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    • 2018
  • Extra-corporeal membrane oxygenation (ECMO) has the potential to rescue patients in cardiac arrest or respiratory failure. ECMO has two systems such as veno-arterial and veno-venous circulation. In cardiac arrest resulting from acute myocardial infarction, veno-arterial ECMO is mandatory for systemic circulation and oxygenation. A 75-year old female patient underwent primary coronary intervention for acute myocardial infarction. Despite successful revascularization, recurrent ventricular tachycardia and heart failure were progressing. We performed a veno-arterial ECMO through the femoral artery and vein, then the patient seemed to be stable clinically. However, laboratory studies, echocardiography, and vital signs indicated multi-organ failure and decreasing cardiac function. We found out an error that we performed veno-venous ECMO instead of veno-arterial ECMO. We added a femoral artery cannula and exchange the circuit system to veno-arterial ECMO. While the systemic circulation seemed to be recovered, the left ventricular function was decreased persistently. A hypovolemia resulting from pulmonary hemorrhage was occurred, which lead to ECMO failure. The patient died of cardiac arrest and multi-organ failure 23 hours after ECMO. Because the color of arterial and venous circuits represent the position and efficacy of ECMO, if unexpected or abnormal circuit colors are detected, prompt and aggressive evaluation for ECMO function is mandatory.

Factors Related to Emotional Leadership in Nurses Manager: Systematic Review and Meta-Analysis (간호관리자의 감성리더십 관련 변인: 체계적 문헌 고찰 및 메타분석)

  • Jang, Se Young;Park, Chan Mi;Yang, Eun Hee
    • Journal of Korean Academy of Nursing
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    • v.54 no.2
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    • pp.119-138
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    • 2024
  • Purpose: This study aimed to identify research trends related to emotional leadership among nurse managers by conducting a systematic literature review and meta-analysis. This study sought to derive insights that could contribute to improving emotional leadership in nursing practice. Methods: A systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) and Meta-Analysis Of Observational Studies in Epidemiology (MOOSE) guidelines. Databases including PubMed, Cumulative Index to Nursing and Allied Health Literature, Scopus, Web of Science, Research Information Sharing Service, Koreanstudies Information Service System, Korean Medical Database, KoreaMed, ScienceON, and DBpia were searched to obtain papers published in English and Korean. Literature searches and screenings were conducted for the period December 1, 2023 to December 17, 2023. The effect size correlation (ESr) was calculated for each variable and the meta-analysis was performed using the statistical software SPSS 29.0, R 4.3.1. Results: Twenty-five (four personal, six job, and fifteen organizational) relevant variables were identified through the systematic review. The results of the meta-analysis showed that the total overall effect size was ESr = .33. Job satisfaction (ESr = .40) and leader-member exchange (ESr = .75) had the largest effect size among the job and organizational-related factors. Conclusion: Emotional leadership helps promote positive changes within organizations, improves organizational effectiveness, and increases member engagement and satisfaction. Therefore, it is considered an important strategic factor in improving organizational performance.