• Journal of Forest and Environmental Science
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• v.35 no.3
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• pp.141-149
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• 2019

Nanocellulose, which can exist as either cellulose nanocrystals or cellulose nanofibrils, has been used as a biomaterial for drug delivery owing to its non-immunogenicity, biocompatibility, high specific area, good mechanical properties, and variability for chemical modification. Various water-soluble drugs can be bound to and released from nanocelluloses through electrostatic interactions. The high specific surface area of nanocellulose allows for high specific drug loading. Additionally, a broad spectrum of drugs can bind to nanocellulose after facile chemical modifications of its surface. Controlled release can be achieved for various pharmaceuticals when the nanocellulose surface is chemically modified or physically formulated in an adequate manner. This review summarizes the potential applications of nanocelluloses in drug delivery according to published studies on drug delivery systems.

• Progress in Medical Physics
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• v.32 no.1
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• pp.1-17
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• 2021

The evolution of X-ray computed tomography (CT) has been based on the discovery of X-rays, the inception of the Radon transform, and the development of X-ray digital data acquisition systems and computer technology. Unlike conventional X-ray imaging (general radiography), CT reconstructs cross-sectional anatomical images of the internal structures according to X-ray attenuation coefficients (approximate tissue density) for almost every region in the body. This article reviews the essential physical principles and technical aspects of the CT scanner, including several notable evolutions in CT technology that resulted in the emergence of helical, multidetector, cone beam, portable, dual-energy, and phase-contrast CT, in integrated imaging modalities, such as positron-emission-tomography-CT and single-photon-emission-computed-tomography-CT, and in clinical applications, including image acquisition parameters, CT angiography, image adjustment, versatile image visualizations, volumetric/surface rendering on a computer workstation, radiation treatment planning, and target localization in radiotherapy. The understanding of CT characteristics will provide more effective and accurate patient care in the fields of diagnostics and radiotherapy, and can lead to the improvement of image quality and the optimization of exposure doses.

• Biotechnology and Bioprocess Engineering:BBE
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• v.8 no.2
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• pp.64-75
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• 2003

Aptamers are functional nucleic acids that can specially bind to proteins, peptides, amino acids. nucleotides, drugs, vitamins and other organic and inorganic compounds. The aptamers are identified from random DNA or RNA libraries by a SELEX (systematic evolution of ligands by exponential amplification) process. As aptamers have the advantage, and potential ability to be released from the limitations of antibodies, they are attractive to a wide range of therapeutic and diagnostic applications. Aptamers, with a high-affinity and specificity, could fulfil molecular the recognition needs of various fields in biotechnology. In this work, we reviewed some aptamer Selection techniques, properties, medical applications of their molecules and their biotechnological applications, such as ELONA (enzyme linked oligonucleotide assay), flow cytometry, biosensors, electrophoresis, chromatography and microarrays.

• Journal of Sensor Science and Technology
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• v.27 no.5
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• pp.280-293
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• 2018

The conversion of an invisible thermal radiation pattern of an object into a visible image using infrared (IR) thermal technology is very useful to understand phenomena what we are interested in. Although IR thermal images were originally developed for military and space applications, they are currently employed to determine thermal properties and heat features in various applications, such as the non-destructive evaluation of industrial equipment, power plants, electricity, military or drive-assisted night vision, and medical applications to monitor heat generation or loss. Recently, IR imaging-based monitoring systems have been considered for application in agricultural, including crop care, plant-disease detection, bruise detection of fruits, and the evaluation of fruit maturity. This paper reviews recent progress in the development of IR thermal imaging techniques and suggests possible applications of thermal imaging techniques in agriculture.

• Nutrition Research and Practice
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• v.1 no.1
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• pp.42-45
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• 2007

Rapid integration of information technology into health care systems has included the use of highly portable systems-in particular, personal digital assistants (PDAs). With their large built-in memories, fast processors, wireless connectivity, multimedia capacity, and large library of applications, PDAs have been widely adopted by physicians and nurses for patient tracking, disease management, medical references and drug information, enhancing quality of health care. Many health-related PDA applications are available to both dietetics professionals and clients. Dietetics professionals can effectively use PDAs for client tracking and support, accessing to hospital database or information, and providing better self-monitoring tools to clients. Internship programs for dietetics professionals should include training in the use of PDAs and their dietetics applications, so that new practitioners can stay abreast of this rapidly evolving technology. Several considerations to keep in mind in selecting a PDA and its applications are discussed.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.113.1-113.1
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• 2014

Surface-enhanced Raman scattering (SERS) has long been projected as a powerful analytical technique for chemical and biological sensing applications. Pairing with portable Raman spectrometers makes the technique extremely appealing as real-time sensors for field application. However, the lack of reliable, uniform, low cost and ease-of-use SERS enhancement structures has prevented the wide adoption of this technique for general applications. We have discovered a novel hybrid structure based on the high-density and uniform arrays of gold nanofingers over a large surface area for SERS applications. The nanofingers are flexible and their tips can be brought together to trap molecules to mimic the biological system. We report here a rapid, simple, low-cost, and sensitive method of detecting trace level of food contaminants by using nanofinger chips based on portable SERS technique. We also present here the characterization of surface reaction of target molecules with our gold nanofinger substrates and the effect of nanofinger closing towards SERS performance. This new type of nano-structures can potentially revolutionize the medical and biologic research by providing a novel way to capture, localize, manipulate, and interrogate biological molecules with unprecedented capabilities.

• Journal of the Korean Society of Systems Engineering
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• v.1 no.2
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• pp.5-11
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• 2005

Ubiquitous computing is an emerging technic for various areas such as public, private (individual), military, industrial, medical sectors. The applications of ubiquitous computing are expected to be prevailed from home to office. Unfortunately, it is not effective to apply existing system/software development methodologies into this emerging ubiquitous computing applications. In this paper, MBASE (Model-Based system Architecting and Software Engineering) is applied as a development method of ubiquitous computing applications. The advantage of MBASE is to identify mismatches of product, process, property, and success models and resolve them in developing the ubiquitous computing applications. A SmartView, a ubiquitous computing application, is presented as a case study o f MBASE.

• International Journal of Oral Biology
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• v.48 no.4
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• pp.45-49
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• 2023

Digital dentistry has witnessed significant advancements in recent years, driven by extensive research following the introduction of cutting-edge technologies such as CAD/CAM and 3D oral scanners. Until now, 2D images obtained via x-ray or CT scans were critical to detect anomalies and for decision-making. This review describes the main principles and applications of supervised, unsupervised, and reinforcement learning in medical applications. In this context, we present a diverse range of artificial intelligence networks with potential applications in dentistry, accompanied by existing results in the field.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4229-4233
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• 2012

With the advances in modern diagnostic expertise for cancer, certain approaches allowing scanning of the complete genome and the proteome are becoming very useful for researchers. These high throughput techniques have already proven power, over traditional detection methods, in differentiating disease sub-types and identifying specific genetic events during progression of cancer. This paper introduces major branches of omics-technology and their applications in the field of cancer. It also addresses current road blocks that need to be overcome and future possibilities of these methods in oncogenic detection.

• IEMEK Journal of Embedded Systems and Applications
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• v.7 no.5
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• pp.219-226
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• 2012

The rises of the life index quality together with the medical technology improvement lead to a longer life expectancy. Then a better health care program, especially for elderly, is needed. The common health problems facing those senior citizens are changed from acute diseases to chronic diseases, such as diabetes, hypertension. Then u-Health takes center stage in medical industry. Although u- Health medical device manufacturers have been improving their instruments, these instruments still rely on proprietary technologies without fixed platform. Even if the interface has been provided by the manufacturer, there is no widely-accepted uniform data model to access data of various u-Health devices. IEEE 11073 is a standard attempting to unify the interfaces of all medical devices. In this paper we have proposed a conversion software platform that assures interoperability among medical devices for ubiquitous sensor network. This module uses in order to develop a standard platform of medical system.